Rachel Koldej

Immune recovery in patients with mantle cell lymphoma receiving long-term ibrutinib and venetoclax combination therapy

Joanne E Davis, Sasanka M Handunnetti, Mandy Ludford-Menting, Chia Sharpe, Piers Blombery, Mary Ann Anderson, Andrew W Roberts, John F Seymour, Constantine S Tam, David S Ritchie, Rachel M Koldej

Journal article  |  2020  |  Blood Advances

Combination venetoclax plus ibrutinib for the treatment of mantle cell lymphoma (MCL) has demonstrated efficacy in the relapsed or..

Serum microRNA is a biomarker for post-operative monitoring in glioma

Andrew Morokoff, Jordan Jones, Hong Nguyen, Chenkai Ma, Arian Lasocki, Frank Gaillard, Iwan Bennett, Rod Luwor, Stanley Stylli, Lucia Paradiso, Rachel Koldej, Iddo Paldor, Ramyar Molania, Terence P Speed, Andrew Webb, Guiseppe Infusini, Jason Li, Charles Malpas, Tomas Kalincik, Katharine Drummond, et al.

Journal article  |  2020  |  Journal of Neuro-Oncology

PURPOSE: A circulating biomarker has potential to provide more accurate information for glioma progression post treatment, however..

Conventional Treatment for Multiple Myeloma Drives Premature Aging Phenotypes and Metabolic Dysfunction in T Cells

Rachel Elizabeth Cooke, Kylie Margaret Quinn, Hang Quach, Simon Harrison, Henry Miles Prince, Rachel Koldej, David Ritchie

Journal article  |  2020  |  Frontiers in Immunology

New diagnoses of multiple myeloma (MM) tend to occur after the age of 60, by which time thymic output is severely reduced. As a co..

Impact of age-, cancer-, and treatment-driven inflammation on T cell function and immunotherapy

Kylie M Quinn, Apriliana ER Kartikasari, Rachel E Cooke, Rachel M Koldej, David S Ritchie, Magdalena Plebanski

Journal article  |  2020  |  Journal of Leukocyte Biology

Many cancers are predominantly diagnosed in older individuals and chronic inflammation has a major impact on the overall health an..

Association between P2X7 Polymorphisms and Post-Transplant Outcomes in Allogeneic Haematopoietic Stem Cell Transplantation

Rachel M Koldej, Travis Perera, Jenny Collins, David S Ritchie

Journal article  |  2020  |  International Journal of Molecular Sciences

Allogeneic stem cell transplantation (alloSCT) is a highly effective treatment method for haematologic malignancies. However, infe..

Differential effects of BTK inhibitors ibrutinib and zanubrutinib on NK-cell effector function in patients with mantle cell lymphoma

Thijs WH Flinsenberg, Charnelle C Tromedjo, Nan Hu, Ye Liu, Yin Guo, Kevin YT Thia, Tahereh Noori, Xiaomin Song, Han X Aw Yeang, Daniela G Tantalo, Sasanka Handunnetti, John F Seymour, Andrew W Roberts, David Ritchie, Rachel Koldej, Paul J Neeson, Lai Wang, Joseph A Trapani, Constantine S Tam, Ilia Voskoboinik

Journal article  |  2020  |  Haematologica: the hematology journal

Three Year Update of the Phase II ABT-199 (Venetoclax) and Ibrutinib in Mantle Cell Lymphoma (AIM) Study

Sasanka M Handunnetti, Mary Ann Anderson, Kate Burbury, Rodney J Hicks, Besiat Birbirsa, Mathias Bressel, Juliana Di Iulio, David Alan Westerman, Stephen Lade, Rishu Agarwal, Mark A Dawson, Sarah-Jane Dawson, Rachel Koldej, David Ritchie, John F Seymour, Andrew W Roberts, Constantine S Tam

Conference Proceedings  |  2019  |  Blood

Nivolumab induces dynamic alterations in CD8 T-cell function and TIM-3 expression when used to treat relapsed acute myeloid leukemia after allogeneic stem cell transplantation

Eric Wong, Joanne Davis, Rachel Koldej, Jeff Szer, Andrew Grigg, David Ritchie

Journal article  |  2019  |  Leukemia & Lymphoma

Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes

Yuhao Jiao, Joanne E Davis, Jai Rautela, Emma M Carrington, Mandy J Ludford-Menting, Wilford Goh, Rebecca B Delconte, Fernando Souza-Fonseca-Guimaraes, Rachel Koldej, Daniel Gray, David Huang, Ben T Kile, Andrew M Lew, David S Ritchie, Nicholas D Huntington

Journal article  |  2019  |  Cell Death & Differentiation

Allogeneic hematopoietic stem cell transplantation (alloSCT) is used to treat over 15,000 patients with acute myeloid leukemia (AM..

Immunotherapeutics in Multiple Myeloma: How Can Translational Mouse Models Help?

Rachel E Cooke, Rachel Koldej, David Ritchie

Journal article  |  2019  |  Journal of Oncology