Carl Kirkwood

Next-generation rotavirus vaccine developers meeting: Summary of a meeting sponsored by PATH and the bill & melinda gates foundation (19-20 June 2019, Geneva).

Alan Fix, Carl D Kirkwood, Duncan Steele, Jorge Flores

Conference Proceedings  |  2020  |  Vaccine

Despite the contribution of currently licensed live, oral rotavirus vaccines (LORVs) to alleviating the burden of severe disease a..

Whole genome in-silico analysis of south african G1P[8] rotavirus strains before and after vaccine introduction over a period of 14 years

PN Mwangi, MT Mogotsi, ML Seheri, MJ Mphahlele, I Peenze, MD Esona, B Kumwenda, AD Steele, CD Kirkwood, VN Ndze, FE Dennis, KC Jere, MM Nyaga

Journal article  |  2020  |  Vaccines

Rotavirus G1P[8] strains account for more than half of the group A rotavirus (RVA) infections in children under five years of age,..

The impact of the rotavirus vaccine on diarrhoea, five years following national introduction in Fiji

Adam WJ Jenney, Rita Reyburn, Felisita T Ratu, Evelyn Tuivaga, Cattram Nguyen, Sokoveti Covea, Sarah Thomas, Eric Rafai, Rachel Devi, Kathryn Bright, Kylie Jenkins, Beth Temple, Lisi Tikoduadua, Joe Kado, E Kim Mulholland, Carl D Kirkwood, Kimberley K Fox, Julie E Bines, Varja Grabovac, Aalisha Sahu Khan, et al.

Journal article  |  2020  |  The Lancet Regional Health - Western Pacific

Submitted

Rotavirus disease and genotype diversity in older children and adults in Australia.

Celeste M Donato, Susie Roczo-Farkas, Carl D Kirkwood, Graeme L Barnes, Julie E Bines

Journal article  |  2020  |  The Journal of Infectious Diseases

BACKGROUND: Rotavirus is a major cause of gastroenteritis in children <5 years of age. The disease burden in older children, adult..

Rotavirus specific maternal antibodies and immune response to RV3-BB rotavirus vaccine in central java and yogyakarta, Indonesia

Margie H Danchin, Julie E Bines, Emma Watts, Daniel Cowley, Daniel Pavlic, Katherine J Lee, Hamidul Huque, Carl Kirkwood, Hera Nirwati, Jarir At Thobari, Cahya Dewi Satria, Yati Soenarto, Vicka Oktaria

Journal article  |  2020  |  Vaccine

BACKGROUND: Placental or breast milk maternal antibodies can potentially reduce oral rotavirus vaccine efficacy in developing coun..

Human Neonatal Rotavirus Vaccine (RV3-BB) Produces Vaccine Take Irrespective of Histo-Blood Group Antigen Status

Karen Boniface, Sean G Byars, Daniel Cowley, Carl D Kirkwood, Julie E Bines

Journal article  |  2020  |  Journal of Infectious Diseases

BACKGROUND: VP4 [P] genotype binding specificities of rotaviruses and differential expression of histo-blood group antigens (HBGAs..

Gene-edited vero cells as rotavirus vaccine substrates

N Orr-Burks, J Murray, W Wu, CD Kirkwood, KV Todd, L Jones, A Bakre, H Wang, B Jiang, RA Tripp

Journal article  |  2019  |  Vaccine: X

Variation of Gut Mucosal Microbiome With Anti-Saccharomyces cerevisiae Antibody Status in Pediatric Crohn Disease.

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of pediatric gastroenterology and nutrition

OBJECTIVES: Crohn disease (CD) is a chronic relapsing condition possibly caused by a dysbiotic microbiome. Approximately 30% to 60..

Variation of Gut Mucosal Microbiome With Anti-Saccharomyces cerevisiae Antibody Status in Pediatric Crohn Disease

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of Pediatric Gastroenterology and Nutrition

OBJECTIVES: Crohn's Disease (CD) is a chronic relapsing condition possibly caused by a dysbiotic microbiome. About 30-60% of CD pa..

The rotavirus vaccine development pipeline.

Carl D Kirkwood, Lyou-Fu Ma, Megan E Carey, A Duncan Steele

Journal article  |  2019  |  Vaccine

Rotavirus disease is a leading global cause of mortality and morbidity in children under 5years of age. The effectiveness of the t..