Carl Kirkwood

Gene-edited vero cells as rotavirus vaccine substrates

N Orr-Burks, J Murray, W Wu, CD Kirkwood, KV Todd, L Jones, A Bakre, H Wang, B Jiang, RA Tripp

Journal article  |  2019  |  Vaccine: X

Variation of Gut Mucosal Microbiome With Anti-Saccharomyces cerevisiae Antibody Status in Pediatric Crohn Disease.

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of pediatric gastroenterology and nutrition

OBJECTIVES: Crohn disease (CD) is a chronic relapsing condition possibly caused by a dysbiotic microbiome. Approximately 30% to 60..

The rotavirus vaccine development pipeline.

Carl D Kirkwood, Lyou-Fu Ma, Megan E Carey, A Duncan Steele

Journal article  |  2019  |  Vaccine

Rotavirus disease is a leading global cause of mortality and morbidity in children under 5years of age. The effectiveness of the t..

Human Neonatal Rotavirus Vaccine (RV3-BB) Produces Vaccine Take Irrespective of Histo-Blood Group Antigen Status.

Karen Boniface, Sean G Byars, Daniel Cowley, Carl D Kirkwood, Julie E Bines

Journal article  |  2019  |  The Journal of Infectious Diseases

BACKGROUND: VP4 [P] genotype binding specificities of rotaviruses and differential expression of histo-blood group antigens (HBGAs..

Immunogenicity of four doses of oral poliovirus vaccine when co-administered with the human neonatal rotavirus vaccine (RV3-BB)

Daniel Cowley, Rini Mulia Sari, Amanda Handley, Emma Watts, Novilia S Bachtiar, Jarir At Thobari, Cahya Dewi Satria, Nada Bogdanovic-Sakran, Hera Nirwati, Francesca Orsini, Katherine J Lee, Carl D Kirkwood, Yati Soenarto, Julie E Bines

Journal article  |  2019  |  Vaccine

BACKGROUND: The RV3-BB human neonatal rotavirus vaccine was developed to provide protection from severe rotavirus disease from bir..

The ORVAC trial protocol: a phase IV, double-blind, randomised, placebo-controlled clinical trial of a third scheduled dose of Rotarix rotavirus vaccine in Australian Indigenous infants to improve protection against gastroenteritis.

Bianca Fleur Middleton, Mark A Jones, Claire S Waddington, Margaret Danchin, Carly McCallum, Sarah Gallagher, Amanda Jane Leach, Ross Andrews, Carl Kirkwood, Nigel Cunliffe, Jonathan Carapetis, Julie A Marsh, Tom Snelling

Journal article  |  2019  |  BMJ Open

INTRODUCTION: Rotavirus vaccines were introduced into the Australian National Immunisation Program in 2007. Despite this, Northern..

Current and new rotavirus vaccines.

Rachel M Burke, Jacqueline E Tate, Carl D Kirkwood, A Duncan Steele, Umesh D Parashar

Journal article  |  2019  |  Current Opinion in Infectious Diseases

PURPOSE OF REVIEW: As of 2019, four rotavirus vaccines have been prequalified by the WHO for use worldwide. This review highlights..

Variation of Gut Mucosal Microbiome with ASCA Status in Pediatric Crohn's Disease.

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of Pediatric Gastroenterology and Nutrition

OBJECTIVES: Crohn's Disease (CD) is a chronic relapsing condition possibly caused by a dysbiotic microbiome. About 30-60% of CD pa..

The Microbiome in Paediatric Crohn's Disease-A Longitudinal, Prospective, Single-Centre Study

Shivani Kansal, Anthony G Catto-Smith, Karen Boniface, Sarah Thomas, Donald J Cameron, Mark Oliver, George Alex, Carl D Kirkwood, Josef Wagner

Journal article  |  2019  |  Journal of Crohn's and Colitis

BACKGROUND AND AIMS: The gut mucosa is the principal site where Crohn's disease [CD] inflammation occurs. Limited information is a..

Higher Sun Exposure is Associated With Lower Risk of Pediatric Inflammatory Bowel Disease: A Matched Case-control Study

Elizabeth Ann Holmes, Anne-Louise Ponsonby, Angela Pezic, Justine A Ellis, Carl D Kirkwood, Robyn M Lucas

Journal article  |  2019  |  Journal of Pediatric Gastroenterology and Nutrition

OBJECTIVES: The incidence of pediatric inflammatory bowel disease (IBD) is increasing worldwide. Ecological studies show higher in..

Phylogenetic and immunoinformatic analysis of VP4, VP7, and NSP4 genes of rotavirus strains circulating in children with acute gastroenteritis in Indonesia

Hera Nirwati, Celeste M Donato, Aqsa Ikram, Abu T Aman, Tri Wibawa, Carl D Kirkwood, Yati Soenarto, Qiuwei Pan, Mohamad S Hakim

Journal article  |  2019  |  Journal of Medical Virology

Experiences with rotavirus vaccines: can we improve rotavirus vaccine impact in developing countries?

AD Steele, JC Victor, ME Carey, JE Tate, DE Atherly, C Pecenka, Z Diaz, UD Parashar, CD Kirkwood

Journal article  |  2019  |  Human Vaccines & Immunotherapeutics

Rotavirus vaccines have been introduced into over 95 countries globally and demonstrate substantial impact in reducing diarrheal m..

Hospital-based surveillance for rotavirus diarrhea in Ulaanbaatar, Mongolia, April 2009 through March 2016.

Altanchimeg Samdan, Sarangua Ganbold, Oyunchimeg Guntev, Solongo Orosoo, Narmandakh Javzandorj, Amar Gongor, Altansukh Enkhtuvshin, Sodbayar Demberelsuren, Wajid Abdul, Youngmee Jee, Varja Grabovac, Carl Kirkwood, Kimberley Fox, Batmunkh Nyambat

Journal article  |  2018  |  Vaccine

BACKGROUND: Diarrheal disease is one of the leading causes of illness and death in young children in the world, especially the dev..

Molecular characterization of rotavirus diarrhea among children aged under five years in the Philippines, 2013-2015

Joseph Bonifacio, Socorro Lupisan, Vito Roque, Maria Joyce Ducusin, Varja Grabovac, Nyambat Batmunkh, James D Heffelfinger, Kimberley Fox, Kohei Toda, Maricel de Quiroz Castro, Carl Kirkwood, Amado Tandoc

Journal article  |  2018  |  Vaccine

Update on vaccines for enteric pathogens.

MS Riddle, WH Chen, CD Kirkwood, CA MacLennan

Journal article  |  2018  |  Clinical Microbiology and Infection

BACKGROUND: Acute diarrhoeal disease caused by viral, bacterial and parasitic infections is a major global health problem; in low-..

Rotavirus Vaccination and the Global Burden of Rotavirus Diarrhea Among Children Younger Than 5 Years

Christopher Troeger, Ibrahim A Khalil, Puja C Rao, Shujin Cao, Brigette F Blacker, Tahmeed Ahmed, George Armah, Julie E Bines, Thomas G Brewer, Danny Colombara, Gagandeep Kang, Beth D Kirkpatrick, Carl D Kirkwood, Jason M Mwenda, Umesh D Parashar, William A Petri, Mark S Riddle, A Duncan Steele, Robert L Thompson, Judd L Walson, et al.

Journal article  |  2018  |  JAMA Pediatrics

Molecular characterisation of rotavirus strains detected during a clinical trial of the human neonatal rotavirus vaccine (RV3-BB) in Indonesia

Daniel Cowley, Hera Nirwati, Celeste M Donato, Nada Bogdanovic-Sakran, Karen Boniface, Carl D Kirkwood, Julie E Bines

Journal article  |  2018  |  Vaccine

The Impact of Rotavirus Vaccines on Genotype Diversity: A Comprehensive Analysis of 2 Decades of Australian Surveillance Data

Susie Roczo-Farkas, Carl D Kirkwood, Daniel Cowley, Graeme L Barnes, Ruth F Bishop, Nada Bogdanovic-Sakran, Karen Boniface, Celeste M Donato, Julie E Bines

Journal article  |  2018  |  The Journal of Infectious Diseases

Characterization of the fecal virome in dogs with chronic enteropathy

Paloma S Moreno, Josef Wagner, Carl D Kirkwood, James R Gilkerson, Caroline S Mansfield

Journal article  |  2018  |  Veterinary Microbiology

Gamma-irradiated rotavirus: A possible whole virus inactivated vaccine

Shabihah Shahrudin, Cheng Chen, Shannon C David, Eve V Singleton, Justin Davies, Carl D Kirkwood, Timothy R Hirst, Michael Beard, Mohammed Alsharifi

Journal article  |  2018  |  PLOS ONE

Estimated impact of rotavirus vaccine on hospitalizations and deaths from rotavirus diarrhea among children <5 in Asia.

Eleanor Burnett, Jacqueline E Tate, Carl D Kirkwood, E Anthony S Nelson, Mathuram Santosham, A Duncan Steele, Umesh D Parashar

Journal article  |  2018  |  Expert Review of Vaccines

BACKGROUND: Of the 215,000 global deaths from rotavirus estimated in 2013, 41% occur in Asian countries. However, despite a recomm..

Multivalent Rotavirus Vaccine and Wild-type Rotavirus Strain Shedding in Australian Infants: A Birth Cohort Study

Suifang Ye, David M Whiley, Robert S Ware, Carl D Kirkwood, Stephen B Lambert, Keith Grimwood

Journal article  |  2018  |  Clinical Infectious Diseases

Human Neonatal Rotavirus Vaccine (RV3-BB) to Target Rotavirus from Birth

JE Bines, J At Thobari, CD Satria, A Handley, E Watts, D Cowley, H Nirwati, J Ackland, J Standish, F Justice, G Byars, KJ Lee, GL Barnes, NS Bachtiar, A Viska Icanervilia, K Boniface, N Bogdanovic-Sakran, D Pavlic, RF Bishop, CD Kirkwood, et al.

Journal article  |  2018  |  New England Journal of Medicine

Serological responses to rotavirus NSP2 following administration of RV3-BB human neonatal rotavirus vaccine

Daniel Cowley, Daniel Pavlic, Nada Bogdanovic-Sakran, Karen Boniface, Carl D Kirkwood, Julie E Bines

Journal article  |  2018  |  Human Vaccines & Immunotherapeutics

Nutritional status, exclusive breastfeeding and management of acute respiratory illness and diarrhea in the first 6 months of life in infants from two regions of Indonesia

V Oktaria, KJ Lee, JE Bines, E Watts, CD Satria, J Atthobari, H Nirwati, CD Kirkwood, Y Soenarto, MH Danchin

Journal article  |  2017  |  BMC Pediatrics

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreaticinflammation

Yu Dou, Howard CH Yim, Carl D Kirkwood, Bryan RG Williams, Anthony J Sadler

Journal article  |  2017  |  The EMBO Journal

Etiology of Severe Acute Watery Diarrhea in Children in the Global Rotavirus Surveillance Network Using Quantitative Polymerase Chain Reaction

Darwin J Operario, James A Platts-Mills, Sandrama Nadan, Nicola Page, Mapaseka Seheri, Jeffrey Mphahlele, Ira Praharaj, Gagandeep Kang, Irene T Araujo, Jose Paulo G Leite, Daniel Cowley, Sarah Thomas, Carl D Kirkwood, Francis Dennis, George Armah, Jason M Mwenda, Pushpa Ranjan Wijesinghe, Gloria Rey, Varja Grabovac, Chipo Berejena, et al.

Journal article  |  2017  |  The Journal of Infectious Diseases

Characterisation of the canine faecal virome in healthy dogs and dogs with acute diarrhoea using shotgun metagenomics

Paloma S Moreno, Josef Wagner, Caroline S Mansfield, Matthew Stevens, James R Gilkerson, Carl D Kirkwood

Journal article  |  2017  |  PLOS ONE

Rotavirus vaccine will have an impact in Asia.

Carl D Kirkwood, A Duncan Steele

Journal article  |  2017  |  PLOS Medicine

Carl Kirkwood and Duncan Steele discuss the evidence supporting rotavirus vaccine deployment in Asian countries.

Detection of Viruses in Weekly Stool Specimens Collected During the First 2 Years of Life: A Pilot Study of Five Healthy Australian Infants in the Rotavirus Vaccine Era

Suifang Ye, David M Whiley, Robert S Ware, Theo P Sloots, Carl D Kirkwood, Keith Grimwood, Stephen B Lambert

Journal article  |  2017  |  Journal of Medical Virology

Protease-activated Receptor 1 Plays a Proinflammatory Role in Colitis by Promoting Th17-related Immunity

Muhammad A Saeed, Garrett Z Ng, Jan Dabritz, Josef Wagner, Louise Judd, Jia-Xi Han, Poshmaal Dhar, Carl D Kirkwood, Philip Sutton

Journal article  |  2017  |  Inflammatory Bowel Diseases

Microbial Factors Associated with Postoperative Crohn's Disease Recurrence

Emily K Wright, Michael A Kamm, Josef Wagner, Shu-Mei Teo, Peter De Cruz, Amy L Hamilton, Kathryn J Ritchie, Michael Inouye, Carl D Kirkwood

Journal article  |  2017  |  Journal of Crohn's and Colitis

Options for improving effectiveness of rotavirus vaccines in developing countries

Marion S Tissera, Daniel Cowley, Nada Bogdanovic-Sakran, Melanie L Hutton, Dena Lyras, Carl D Kirkwood, Jim P Buttery

Journal article  |  2017  |  Human Vaccines & Immunotherapeutics

Rotavirus specific maternal antibodies and immune response to RV3-BB neonatal rotavirus vaccine in New Zealand

Mee-Yew Chen, Carl D Kirkwood, Julie Bines, Daniel Cowley, Daniel Pavlic, Katherine J Lee, Francesca Orsini, Emma Watts, Graeme Barnes, Margaret Danchin

Journal article  |  2017  |  Human Vaccines & Immunotherapeutics

Rotavirus shedding following administration of RV3-BB human neonatal rotavirus vaccine

Daniel Cowley, Karen Boniface, Nada Bogdanovic-Sakran, Carl D Kirkwood, Julie E Bines

Journal article  |  2017  |  Human Vaccines & Immunotherapeutics

AUSTRALIAN ROTAVIRUS SURVEILLANCE PROGRAM ANNUAL REPORT, 2015

Susie Roczo-Farkas, Carl D Kirkwood, Julie E Bines

Journal article  |  2016  |  Communicable diseases intelligence quarterly report

Increased Rotavirus Prevalence in Diarrheal Outbreak Precipitated by Localized Flooding, Solomon Islands, 2014

Forrest K Jones, Albert I Ko, Chris Becha, Cynthia Joshua, Jennie Musto, Sarah Thomas, AxeIle Ronsse, Carl D Kirkwood, Alison Sio, Audrey Aumua, Eric J Nilles

Journal article  |  2016  |  Emerging Infectious Diseases

Emergence of a novel equine-like G3P[8] inter-genogroup reassortant rotavirus strain associated with gastroenteritis in Australian children

Daniel Cowley, Celeste M Donato, Susie Roczo-Farkas, Carl D Kirkwood

Journal article  |  2016  |  Journal of General Virology

Safety and immunogenicity of RV3-BB human neonatal rotavirus vaccine administered at birth or in infancy: a randomised, double-blind, placebo-controlled trial

Julie E Bines, Margaret Danchin, Pamela Jackson, Amanda Handley, Emma Watts, Katherine J Lee, Amanda West, Daniel Cowley, Mee-Yew Chen, Graeme L Barnes, Frances Justice, Jim P Buttery, John B Carlin, Ruth F Bishop, Barry Taylor, Carl D Kirkwood

Journal article  |  2015  |  The Lancet Infectious Diseases

Are identity badges and lanyards in pediatrics potentially contaminated with viral pathogens?

Chun Yi Ting, Daryl R Cheng, Despina Kotsanas, Carl D Kirkwood, Nada Bogdanovic-Sakran, Rhonda L Stuart, Jim P Buttery

Journal article  |  2015  |  American Journal of Infection Control

Genome-Wide Evolutionary Analyses of G1P[8] Strains Isolated Before and After Rotavirus Vaccine Introduction

Mark Zeller, Celeste Donato, Nidia Sequeira Trovao, Daniel Cowley, Elisabeth Heylen, Nicole C Donker, John K McAllen, Asmik Akopov, Ewen F Kirkness, Philippe Lemey, Marc Van Ranst, Jelle Matthijnssens, Carl D Kirkwood

Journal article  |  2015  |  Genome Biology and Evolution

Emerging OP354-Like P[8] Rotaviruses Have Rapidly Dispersed from Asia to Other Continents

Mark Zeller, Elisabeth Heylen, Susan Damanka, Corinna Pietsch, Celeste Donato, Tsutomu Tamura, Ruta Kulkarni, Ritu Arora, Nigel Cunliffe, Leena Maunula, Christiaan Potgieter, Sana Tamim, Sarah De Coster, Elena Zhirakovskaya, Salwa Bdour, Helen O'Shea, Carl D Kirkwood, Mapaseka Seheri, Martin Monene Nyaga, Jeffrey Mphahlele, et al.

Journal article  |  2015  |  Molecular Biology and Evolution

Recent Advances in Characterizing the Gastrointestinal Microbiome in Crohn's Disease: A Systematic Review

Emily K Wright, Michael A Kamm, Shu Mei Teo, Michael Inouye, Josef Wagner, Carl D Kirkwood

Journal article  |  2015  |  Inflammatory Bowel Diseases

Association between specific mucosa-associated microbiota in Crohn's disease at the time of resection and subsequent disease recurrence: A pilot study

Peter De Cruz, Seungha Kang, Josef Wagner, Michael Buckley, Winnie H Sim, Lani Prideaux, Trevor Lockett, Chris McSweeney, Mark Morrison, Carl D Kirkwood, Michael A Kamm

Journal article  |  2015  |  Journal of Gastroenterology and Hepatology

Conquering rotavirus: From discovery to global vaccine implementation

Julie E Bines, Carl D Kirkwood

Journal article  |  2015  |  Journal of Paediatrics and Child Health

Comparison of Test Specificities of Commercial Antigen-Based Assays and In-House PCR Methods for Detection of Rotavirus in Stool Specimens

S Ye, SB Lambert, K Grimwood, S Roczo-Farkas, GR Nimmo, TP Sloots, CD Kirkwood, DM Whiley

Journal article  |  2015  |  Journal of Clinical Microbiology

Novel porcine-like human G26P[19] rotavirus identified in hospitalized paediatric diarrhoea patients in Ho Chi Minh City, Vietnam

Vu Tra My Phan, Maia A Rabaa, Celeste Donato, Daniel Cowley, Vinh Phat Voong, Thi Ngoc Dung Iran, Hong Anh Pham, Vinh Ha, Juliet E Bryant, Paul Kellam, Guy Thwaites, Mark EJ Woolhouse, Carl D Kirkwood, Stephen Baker

Journal article  |  2014  |  Journal of General Virology

Characterization of G2P[4] rotavirus strains associated with increased detection in Australian states using the RotaTeq (R) vaccine during the 2010-2011 surveillance period

Celeste M Donato, Zheng Andrew Zhang, Nicole C Donker, Carl D Kirkwood

Journal article  |  2014  |  Infection, Genetics and Evolution

Characterization of G2P[4] rotavirus strains causing outbreaks of gastroenteritis in the Northern Territory, Australia, in 1999, 2004 and 2009

Celeste M Donato, Daniel Cowley, Nicole C Donker, Nada Bogdanovic-Sakran, Thomas L Snelling, Carl D Kirkwood

Journal article  |  2014  |  Infection, Genetics and Evolution

Intussusception is associated with the detection of adenovirus C, enterovirus B and rotavirus in a rotavirus vaccinated population

Cara A Minney-Smith, Avram Levy, Meredith Hodge, Peter Jacoby, Simon H Williams, Dale Carcione, Susie Roczo-Farkas, Carl D Kirkwood, David W Smith

Journal article  |  2014  |  Journal of Clinical Virology

Geographic variation in the eukaryotic virome of human diarrhea

Lori R Holtz, Song Cao, Guoyan Zhao, Irma K Bauer, Donna M Denno, Eileen J Klein, Martin Antonio, O Cohn Stine, Thomas L Snelling, Carl D Kirkwood, David Wang

Journal article  |  2014  |  Virology

Rotavirus Infection Induces Transient Pancreatic Involution and Hyperglycemia in Weanling Mice

Margo C Honeyman, David Laine, Yifan Zhan, Sarah Londrigan, Carl Kirkwood, Leonard C Harrison

Journal article  |  2014  |  PLoS ONE

What can rotavirus vaccines teach us about rotavirus?

Jim P Buttery, Carl D Kirkwood

Journal article  |  2014  |  The Lancet Infectious Diseases

SNP genotyping of animal and human derived isolates of Mycobacterium avium subsp paratuberculosis

James W Wynne, Christie Beller, Victoria Boyd, Barry Francis, Jacek Gwozdz, Marios Carajias, Hans G Heine, Josef Wagner, Carl D Kirkwood, Wojtek P Michalski

Journal article  |  2014  |  Veterinary Microbiology

Characterization of a G1P[8] rotavirus causing an outbreak of gastroenteritis in the Northern Territory, Australia, in the vaccine era

Celeste M Donato, Daniel Cowley, Thomas L Snelling, Asmik Akopov, Ewen F Kirkness, Carl D Kirkwood

Journal article  |  2014  |  Emerging Microbes & Infections

Genetic characterization of a novel G3P[14] rotavirus strain causing gastroenteritis in 12 year old Australian child

Celeste M Donato, Nicholas M Manuelpillai, Daniel Cowley, Susie Roczo-Farkas, Jim P Buttery, Nigel W Crawford, Carl D Kirkwood

Journal article  |  2014  |  Infection Genetics and Evolution

Identification and Characterization of Antibody-Binding Epitopes on the Norovirus GII.3 Capsid

Jackie E Mahar, Nicole C Donker, Karin Bok, Gert H Talbo, Kim Y Green, Carl D Kirkwood

Journal article  |  2014  |  Journal of Virology

Novel G10P[14] Rotavirus Strain, Northern Territory, Australia

Daniel Cowley, Celeste M Donato, Susie Roczo-Farkas, Carl D Kirkwood

Journal article  |  2013  |  Emerging Infectious Diseases

TLR4, IL10RA, and NOD2 mutation in paediatric Crohn's disease patients: an association with Mycobacterium avium subspecies paratuberculosis and TLR4 and IL10RA expression

Josef Wagner, Narelle A Skinner, Anthony G Catto-Smith, Donald JS Cameron, Wojtek P Michalski, Kumar Visvanathan, Carl D Kirkwood

Journal article  |  2013  |  Medical Microbiology and Immunology

Bacteriophages in Gut Samples From Pediatric Crohn's Disease Patients: Metagenomic Analysis Using 454 Pyrosequencing

Josef Wagner, Jovana Maksimovic, Gabriella Farries, Winnie H Sim, Ruth F Bishop, Donald J Cameron, Anthony G Catto-Smith, Carl D Kirkwood

Journal article  |  2013  |  Inflammatory Bowel Diseases

Phase I trial of RV3-BB rotavirus vaccine: A human neonatal rotavirus vaccine

M Danchin, CD Kirkwood, KJ Lee, RF Bishop, E Watts, FA Justice, V Clifford, D Cowley, JP Buttery, JE Bines

Journal article  |  2013  |  Vaccine

Evidence of false-positive results in a commercially available rotavirus assay in the vaccine era, Australia, 2011 to 2012

S Ye, S Roczo-Farkas, DM Whiley, SB Lambert, J Robson, C Heney, G Nimmo, K Grimwood, TP Sloots, CD Kirkwood

Journal article  |  2013  |  Eurosurveillance

Current knowledge and systematic review of viruses associated with Crohn's disease

Josef Wagner, Winnie H Sim, Katherine J Lee, Carl D Kirkwood

Journal article  |  2013  |  Reviews in Medical Virology

The Importance of Intergenic Recombination in Norovirus GII.3 Evolution

Jackie E Mahar, Karin Bok, Kim Y Green, Carl D Kirkwood

Journal article  |  2013  |  Journal of Virology

Pseudomonas Infection in Children with Early-onset Crohn's Disease: An Association with a Mutation Close to PSMG1

Josef Wagner, Anthony G Catto-Smith, Donald JS Cameron, Carl D Kirkwood

Journal article  |  2013  |  Inflammatory Bowel Diseases

Changes in the epidemiology of gastroenteritis in a paediatric short stay unit following the introduction of rotavirus immunisation

Jonathan D Akikusa, Sandy M Hopper, Julian J Kelly, Carl D Kirkwood, Jim P Buttery

Journal article  |  2013  |  Journal of Paediatrics and Child Health

Enteral Nutrition in Crohn's Disease: An Underused Therapy

S Kansal, J Wagner, CD Kirkwood, AG Catto-Smith

Journal article  |  2013  |  Gastroenterology Research and Practice

Short Report: Surveillance and Molecular Characterization of Group A Rotaviruses in Goroka, Papua New Guinea

Paul Francis Horwood, Dagwin Luang-Suarkia, Sauli Bebes, Karen Boniface, Siddhartha Sankar Datta, Peter Max Siba, Carl Dunn Kirkwood

Journal article  |  2012  |  American Journal of Tropical Medicine and Hygiene

Group A rotavirus universal mass vaccination: how and to what extent will selective pressure influence prevalence of rotavirus genotypes?

Jelle Matthijnssens, Osamu Nakagomi, Carl D Kirkwood, Max Ciarlet, Ulrich Desselberger, Marc Van Ranst

Journal article  |  2012  |  Expert Review of Vaccines

Selection and evolutionary analysis in the nonstructural protein NSP2 of rotavirus A

Nicole C Donker, Carl D Kirkwood

Journal article  |  2012  |  Infection Genetics and Evolution

Gut microbiota at the time of Crohn's resection predicts development of disease recurrence

Peter De Cruz, Seungha Kang, Winnie H Sim, Michael Buckley, Josef Wagner, Lani Prideaux, Mark Morrison, Chris Mcsweeney, Carl Kirkwood, Michael A Kamm

Conference Proceedings  |  2012  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Identification of Strains of RotaTeq Rotavirus Vaccine in Infants With Gastroenteritis Following Routine Vaccination

Celeste M Donato, Ling Sing Ch'ng, Karen F Boniface, Nigel W Crawford, Jim P Buttery, Michael Lyon, Ruth F Bishop, Carl D Kirkwood

Journal article  |  2012  |  Journal of Infectious Diseases

Expression profile of genes involved in pathogenesis of pediatric Crohn's disease

Winnie H Sim, Josef Wagner, Donald J Cameron, Anthony G Catto-Smith, Ruth F Bishop, Carl D Kirkwood

Journal article  |  2012  |  Journal of Gastroenterology and Hepatology

Characterisation of a G9P[8] rotavirus strain identified during a gastroenteritis outbreak in Alice Springs, Australia post Rotarix (TM) vaccine introduction

CM Donato, D Cannan, N Bogdanovic-Sakran, TL Snelling, CD Kirkwood

Journal article  |  2012  |  Vaccine

Characterization of the gastrointestinal microbiota in health and inflammatory bowel disease

Peter De Cruz, Lani Prideaux, Josef Wagner, Siew C Ng, Chris McSweeney, Carl Kirkwood, Mark Morrison, Michael A Kamm

Journal article  |  2012  |  Inflammatory Bowel Diseases

Identification of strains of rotavirus vaccine RotaTeq(R) in infants with gastroenteritis following routine vaccination

M Donato, undefined Ch'ng, F Boniface, NW Crawford, JP Buttery, undefined Lyon, RF Bishop, CD Kirkwood

Journal article  |  2012  |  Journal of Infectious Diseases

Rotavirus Cerebellitis: New Aspects to an Old Foe?

Melanie J Thompson, Peter J Gowdie, Carl D Kirkwood, Richard R Doherty, Michael Fahey

Journal article  |  2012  |  Pediatric Neurology

Characterization of Norovirus Strains in Australian Children From 2006 to 2008: Prevalence of Recombinant Strains

Jackie E Mahar, Carl D Kirkwood

Journal article  |  2011  |  Journal of Medical Virology

Recurrent intussusception in infants

Frances A Justice, T Nguyen Liem, N Tran Son, Carl D Kirkwood, Thi Thi Ngo, John B Carlin, Julie E Bines

Journal article  |  2011  |  Journal of Paediatrics and Child Health

Phylogenetic analysis of rotavirus A NSP2 gene sequences and evidence of intragenic recombination

Nicole C Donker, Karen Boniface, Carl D Kirkwood

Journal article  |  2011  |  Infection Genetics and Evolution

Identification of an antibody-binding epitope on the rotavirus A non-structural protein NSP2 using phage display analysis

Nicole C Donker, Michael Foley, Debra C Tamvakis, Ruth Bishop, Carl D Kirkwood

Journal article  |  2011  |  Journal of General Virology

Comparative Evolution of GII.3 and GII.4 Norovirus over a 31-Year Period

Denali Boon, Jackie E Mahar, Eugenio J Abente, Carl D Kirkwood, Robert H Purcell, Albert Z Kapikian, Kim Y Green, Karin Bok

Journal article  |  2011  |  Journal of Virology

Mycobacterium avium Subspecies paratuberculosis in Children with Early-onset Crohn's Disease: A Longitudinal Follow-up Study

Josef Wagner, Winnie Sim, Ruth F Bishop, Anthony G Catto-Smith, Donald JS Cameron, Carl D Kirkwood

Journal article  |  2011  |  Inflammatory Bowel Diseases

Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG)

Jelle Matthijnssens, Max Ciarlet, Sarah M McDonald, Houssam Attoui, Krisztian Banyai, J Rodney Brister, Javier Buesa, Mathew D Esona, Mary K Estes, Jon R Gentsch, Miren Iturriza-Gomara, Reimar Johne, Carl D Kirkwood, Vito Martella, Peter PC Mertens, Osamu Nakagomi, Viviana Parreno, Mustafizur Rahman, Franco M Ruggeri, Linda J Saif, et al.

Journal article  |  2011  |  Archives of Virology

Exploring the Zoonotic Potential of Mycobacterium avium Subspecies paratuberculosis through Comparative Genomics

James W Wynne, Tim J Bull, Torsten Seemann, Dieter M Bulach, Josef Wagner, Carl D Kirkwood, Wojtek P Michalski

Journal article  |  2011  |  PLoS One

Rare Rotavirus Strains in Children with Severe Diarrhea, Malaysia

Ling-Sing Ch'ng, Way S Lee, Carl D Kirkwood

Journal article  |  2011  |  Emerging Infectious Diseases

Maternal antibodies to rotavirus: Could they interfere with live rotavirus vaccines in developing countries?

J Chan, H Nirwati, R Triasih, N Bogdanovic-Sakran, Y Soenarto, M Hakimi, T Duke, JP Buttery, JE Bines, RF Bishop, CD Kirkwood, MD Danchin

Journal article  |  2011  |  Vaccine

Reduction in Rotavirus-associated Acute Gastroenteritis Following Introduction of Rotavirus Vaccine Into Australia's National Childhood Vaccine Schedule

Jim P Buttery, Stephen B Lambert, Keith Grimwood, Michael D Nissen, Emma J Field, Kristine K Macartney, Jonathan D Akikusa, Julian J Kelly, Carl D Kirkwood

Journal article  |  2011  |  Pediatric Infectious Disease Journal

Prospective Evaluation of the Mucosa-Associated Microbiota Using 454 Pyrosequencing at Crohn's Surgery and 6 Months Later Reveals Loss of Diversity and Specific Phyla Changes Associated With Disease Recurrence

P De Cruz, J Wagner, L Prideaux, CD Kirkwood, M Kamm

Journal article  |  2011  |  Gastroenterology

Distribution of Rotavirus Genotypes After Introduction of Rotavirus Vaccines, Rotarix (R) and RotaTeq (R), into the National Immunization Program of Australia

Carl D Kirkwood, Karen Boniface, Graeme L Barnes, Ruth F Bishop

Journal article  |  2011  |  Pediatric Infectious Disease Journal

Interaction of Crohn's Disease Susceptibility Genes in an Australian Paediatric Cohort

Josef Wagner, Winnie H Sim, Justine A Ellis, Eng K Ong, Anthony G Catto-Smith, Donald JS Cameron, Ruth F Bishop, Carl D Kirkwood

Journal article  |  2010  |  PLoS One

Genetic and Antigenic Diversity of Human Rotaviruses: Potential Impact on Vaccination Programs

Carl D Kirkwood

Journal article  |  2010  |  Journal of Infectious Diseases

An Outbreak of Necrotizing Enterocolitis Associated With Norovirus Genotype GII.3

Rhonda L Stuart, Kenneth Tan, Jackie E Mahar, Carl D Kirkwood, C Andrew Ramsden, Nick Andrianopoulos, Damien Jolley, Kaye Bawden, Richard Doherty, Despina Kotsanas, Jennifer Bradford, Jim P Buttery

Journal article  |  2010  |  Pediatric Infectious Disease Journal

Novel Burkholderiales 23S rRNA Genes Identified in Ileal Biopsy Samples from Children: Preliminary Evidence that a Subtype Is Associated with Perianal Crohn's Disease

WH Sim, J Wagner, DJ Cameron, AG Catto-Smith, RF Bishop, CD Kirkwood

Journal article  |  2010  |  Journal of Clinical Microbiology

Rapid and Sensitive Detection of Rotavirus Molecular Signatures Using Surface Enhanced Raman Spectroscopy

Jeremy D Driskell, Yu Zhu, Carl D Kirkwood, Yiping Zhao, Richard A Dluhy, Ralph A Tripp

Journal article  |  2010  |  PLoS One

Circulating Human Group A Rotavirus Genotypes in Malaysia

H Zuridah, CD Kirkwood, N Bogdanovic-Sakran, RF Bishop, KL Yap

Journal article  |  2010  |  Journal of Medical Virology

Characterisation of G8 human rotaviruses in Australian children with gastroenteritis

Dayna L Swiatek, Enzo A Palombo, Alvin Lee, Michael J Coventry, Margaret L Britz, Carl D Kirkwood

Journal article  |  2010  |  Virus Research

Detection and analysis of bovine rotavirus strains circulating in Australian calves during 2004 and 2005

DL Swiatek, EA Palombo, A Lee, MJ Coventry, ML Britz, CD Kirkwood

Journal article  |  2010  |  Veterinary Microbiology

Genotyping of rotavirus isolates collected from children less than 5 years of age admitted for diarrhoea at the Yangon Children's Hospital, Myanmar

Kyaw Moe, Hlaing Myat Thu, Win Mar Oo, Khin Mar Aye, Thin Thin Shwe, Win Mar, Carl D Kirkwood

Journal article  |  2009  |  Vaccine

Rotavirus strain surveillance-An Australian perspective of strains causing disease in hospitalised children from 1997 to 2007

Carl D Kirkwood, Karen Boniface, Nada Bogdanovic-Sakran, Paul Masendycz, Graeme L Barnes, Ruth F Bishop

Journal article  |  2009  |  Vaccine

The burden of hospitalised rotavirus infections in Fiji

Adam Jenney, Lisi Tikoduadua, Eka Buadromo, Graeme Barnes, Carl D Kirkwood, Karen Boniface, Julie Bines, Kim Mulholland, Fiona Russell

Journal article  |  2009  |  Vaccine

Mycobacterium avium Subspecies paratuberculosis in Children with Early-Onset Crohn's Disease

Carl D Kirkwood, Josef Wagner, Karen Boniface, Jill Vaughan, Wojtek P Michalski, Anthony G Catto-Smith, Don JS Cameron, Ruth F Bishop

Journal article  |  2009  |  Inflammatory Bowel Diseases

Calicivirus shedding in children after recovery from diarrhoeal disease

Carl D Kirkwood, Rick Streitberg

Journal article  |  2008  |  Journal of Clinical Virology

Identification and Characterisation of Pseudomonas 16S Ribosomal DNA from Ileal Biopsies of Children with Crohn's Disease

Josef Wagner, Kirsty Short, Anthony G Catto-Smith, Don JS Cameron, Ruth F Bishop, Carl D Kirkwood

Journal article  |  2008  |  PLoS One

New oligonucleotide primers for P-typing of rotavirus strains: Strategies for typing previously untypeable strains

Mirjam Kuehne Simmonds, George Armah, Richard Asmah, Indrani Banerjee, Susan Damanka, Mathew Esona, Jon R Gentsch, Jim J Gray, Carl Kirkwood, Nicola Page, Miren Iturriza-Gomara

Journal article  |  2008  |  Journal of Clinical Virology

Non-structural protein NSP2 induces heterotypic antibody responses during primary rotavirus infection and reinfection in children

Carl D Kirkwood, Karen Boniface, Simone Richardson, Zenobia F Taraporewala, John T Patton, Ruth F Bishop

Journal article  |  2008  |  Journal of Medical Virology

Risk factors for intussusception in infants in Vietnam and Australia: Adenovirus implicated, but not rotavirus

Julie E Bines, Nguyen Thanh Liem, Frances A Justice, Tran Ngoc Son, Carl D Kirkwood, Margaret De Campo, Peter Barnett, Ruth F Bishop, Roy Robins-Browne, John B Carlin

Journal article  |  2006  |  Journal of Pediatrics

Molecular epidemiology of adenovirus isolates from patients diagnosed with intussusception in Melbourne, Australia

Gowri Selvaraj, Carl Kirkwood, Julie Bines, Jim Buttery

Journal article  |  2006  |  Journal of Clinical Microbiology

Genetic variation of NSP1 and NSP4 genes among serotype G9 rotaviruses causing hospitalization of children in Melbourne, Australia, 1997-2002

Kiran Shah, Carl D Kirkwood, Mrinal Bhave, Enzo A Palombo

Journal article  |  2006  |  Journal of Medical Virology

Serotype diversity and reassortment between human and animal rotavirus strains: Implications for rotavirus vaccine programs

JR Gentsch, AR Laird, B Bielfelt, DD Griffin, K Banyai, M Ramachandran, V Jain, NA Cunliffe, O Nakagomi, CD Kirkwood, TK Fischer, UD Parashar, JS Bresee, B Jiang, RI Glass

Journal article  |  2005  |  Journal of Infectious Diseases

A 5-year study of the prevalence and genetic diversity of human caliciviruses associated with sporadic cases of acute gastroenteritis in young children admitted to hospital in Melbourne, Australia (1998-2002)

CD Kirkwood, R Clark, N Bogdanovic-Sakran, RF Bishop

Journal article  |  2005  |  Journal of Medical Virology

Rotavirus serotype G9P[8] and acute gastroenteritis outbreak in children, Northern Australia

C Kirkwood, N Bogdanovic-Sakran, G Barnes, R Bishop

Journal article  |  2004  |  Emerging Infectious Diseases

Viral gastroenteritis in Europe: a new norovirus variant?

C Kirkwood

Journal article  |  2004  |  The Lancet

Rotavirus antigenaemia and viraemia: a common event?

SE Blutt, CD Kirkwood, V Parreno, KL Warfield, M Ciarlet, MK Estes, K Bok, RF Bishop, ME Conner

Journal article  |  2003  |  The Lancet

Genetic and antigenic characterization of rotavirus serotype G9 strains isolated in Australia between 1997 and 2001

C Kirkwood, N Bogdanovic-Sakran, E Palombo, P Masendycz, H Bugg, G Barnes, R Bishop

Journal article  |  2003  |  Journal of Clinical Microbiology

Excretion of serotype G1 rotavirus strains by asymptomatic staff: A possible source of nosocomial infection

GL Barnes, SL Callaghan, CD Kirkwood, N Bogdanovic-Sakran, LJ Johnston, RF Bishop

Journal article  |  2003  |  Journal of Pediatrics

Rotavirus vaccines - an update

CD Kirkwood, J Buttery

Journal article  |  2003  |  Expert Opinion on Biological Therapy

Detection and characterization of rotaviruses in hospitalized neonates in Blantyre, Malawi

NA Cunliffe, S Rogerson, W Dove, BDM Thindwa, J Greensill, CD Kirkwood, RL Broadhead, CA Hart

Journal article  |  2002  |  Journal of Clinical Microbiology

Characterization of nontypeable rotavirus strains from the United States: Identification of a new rotavirus reassortant (P2A[6],G12) and rare P3[9] strains related to bovine rotaviruses

DD Griffin, T Nakagomi, Y Hoshino, O Nakagomi, CD Kirkwood, UD Parashar, RI Glass, JR Gentsch

Journal article  |  2002  |  Virology

Effect of concomitant HIV infection on presentation and outcome of rotavirus gastroenteritis in Malawian children

NA Cunliffe, JS Gondwe, CD Kirkwood, SM Graham, NM Nhlane, BDM Thindwa, W Dove, RL Broadhead, ME Molyneux, CA Hart

Journal article  |  2001  |  The Lancet

Report of the Australian Rotavirus Surveillance Program, 2000/2001.

P Masendycz, N Bogdanovic-Sakran, C Kirkwood, R Bishop, G Barnes

Journal article  |  2001  |  Communicable Diseases Intelligence

The National Rotavirus Reference Centre together with 15 collaborating laboratories Australia-wide conducted rotavirus surveillanc..

Molecular detection of human calicivirus in young children hospitalized with acute gastroenteritis in Melbourne, Australia, during 1999

CD Kirkwood, RF Bishop

Journal article  |  2001  |  Journal of Clinical Microbiology