Clara Gaff

Rapid acute care genomics: Challenges and opportunities for genetic counselors

Fiona Lynch, Amy Nisselle, Clara L Gaff, Belinda McClaren

Journal article  |  2020  |  Journal of Genetic Counseling

Genomic medicine in pediatric acute care is showing great promise, with rapid results from exome and genome sequencing returned wi..

Introducing Edna: A trainee chatbot designed to support communication about additional (secondary) genomic findings.

David Ireland, DanaKai Bradford, Emma Szepe, Ella Lynch, Melissa Martyn, David Hansen, Clara Gaff

Journal article  |  2020  |  Patient Education and Counseling

OBJECTIVE: To support informed decision-making about reanalysis of clinical genomic data for risk of preventable conditions ('addi..

Professional regulation for Australasian genetic counselors

Cass Hoskins, Clara Gaff, Alison McEwen, Ivan Macciocca, Amy Pearn, Carolyn Shalhoub, Hayley Salvemini, Jennifer Berkman, Kate E Riley, Rachel Williams, Michael Milward, Mary-Anne Young

Journal article  |  2020  |  Journal of Genetic Counseling

As a result of the ongoing global expansion of genetic counseling, the need to formalize a system of professional regulation for g..

Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

Iris Kramer, Maartje J Hooning, Nasim Mavaddat, Michael Hauptmann, Renske Keeman, Ewout W Steyerberg, Daniele Giardiello, Antonis C Antoniou, Paul DP Pharoah, Sander Canisius, Zumuruda Abu-Ful, Irene L Andrulis, Hoda Anton-Culver, Kristan J Aronson, Annelie Augustinsson, Heiko Becher, Matthias W Beckmann, Sabine Behrens, Javier Benitez, Marina Bermisheva, et al.

Journal article  |  2020  |  American Journal of Human Genetics

Previous research has shown that polygenic risk scores (PRSs) can be used to stratify women according to their risk of developing ..

EARLY GENOMIC SEQUENCING INCREASES DIAGNOSTIC YIELD AND IS COST EFFECTIVE IN CHILDREN

K Jayasinghe, E Wu, P Kerr, A Mallett, Z Stark, M Martyn, C Gaff, I Goranitis, C Quinlan

Conference Proceedings  |  2020  |  NEPHROLOGY

"It's something I've committed to longer term": The impact of an immersion program for physicians on adoption of genomic medicine.

Melissa Martyn, Belinda McClaren, Monika Janinski, Elly Lynch, Fiona Cunningham, Clara Gaff

Journal article  |  2020  |  Patient Education and Counseling

OBJECTIVE: To foster implementation of genomic testing in medical care by providing a cadre of physicians with 'hands on' experien..

Clinical impact of genomic testing in patients with suspected monogenic kidney disease

Kushani Jayasinghe, Zornitza Stark, Peter G Kerr, Clara Gaff, Melissa Martyn, John Whitlam, Belinda Creighton, Elizabeth Donaldson, Matthew Hunter, Anna Jarmolowicz, Lilian Johnstone, Emma Krzesinski, Sebastian Lunke, Elly Lynch, Kathleen Nicholls, Chirag Patel, Yael Prawer, Jessica Ryan, Emily J See, Andrew Talbot, et al.

Journal article  |  2020  |  Genetics in Medicine

PURPOSE: To determine the diagnostic yield and clinical impact of exome sequencing (ES) in patients with suspected monogenic kidne..

A cost-effectiveness analysis of genomic sequencing in a prospective versus historical cohort of complex pediatric patients

Alison Yeung, Natalie B Tan, Tiong Y Tan, Zornitza Stark, Natasha Brown, Matthew F Hunter, Martin Delatycki, Chloe Stutterd, Ravi Savarirayan, George Mcgillivray, Rachel Stapleton, Smitha Kumble, Lilian Downie, Matthew Regan, Sebastian Lunke, Belinda Chong, Dean Phelan, Gemma R Brett, Anna Jarmolowicz, Yael Prawer, et al.

Journal article  |  2020  |  Genetics in Medicine

PURPOSE: Cost-effectiveness evaluations of first-line genomic sequencing (GS) in the diagnosis of children with genetic conditions..

Editorial: Educating Health Professionals in Genomic Medicine: Evidence-Based Strategies and Approaches

Sylvia A Metcalfe, Michael J Dougherty, Clara L Gaff

Journal article  |  2020  |  Frontiers in Genetics

Evaluating barriers to uptake of comprehensive genomic profiling (CGP) in advanced cancer patients (pts).

Kortnye Maureen Smith, Sophie O Haire, Anh Khuong-Quang Dong, Ben Markman, Hui Kong Gan, Paul G Ekert, Kenneth John O'Byrne, Michael Millward, Benjamin J Solomon, Ben Tran, Clare L Scott, Damien Kee, Grant A McArthur, Andrew Fellowes, Rona Weerasuriya, Elly Lynch, Melissa Martyn, Clara Gaff, Stephen B Fox, Jayesh Desai

Conference Proceedings  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY