Ethan Goddard-Borger

A subfamily classification to choreograph the diverse activities within Glycoside Hydrolase family 31 (GH31).

Thimali Arumapperuma, Jinling Li, Bastian Hornung, Niccolay Madiedo Soler, Ethan D Goddard-Borger, Nicolas Terrapon, Spencer J Williams

Journal article  |  2023  |  J Biol Chem

The Carbohydrate-Active Enzyme classification groups enzymes that breakdown, assemble or decorate glycans into protein families ba..

Conservation, abundance, glycosylation profile, and localization of the TSP protein family in Cryptosporidium parvum.

Alan John, Stefanie M Bader, Niccolay Madiedo Soler, Kharizta Wiradiputri, Swapnil Tichkule, Sean T Smyth, Stuart A Ralph, Aaron R Jex, Nichollas E Scott, Christopher J Tonkin, Ethan D Goddard-Borger

Journal article  |  2023  |  J Biol Chem

Cryptosporidium parvum is a zoonotic apicomplexan parasite and a common cause of diarrheal disease worldwide. The development of v..

Structure, sequon recognition and mechanism of tryptophan C-mannosyltransferase

Joel S Bloch, Alan John, Runyu Mao, Somnath Mukherjee, Jeremy Boilevin, Rossitza N Irobalieva, Tamis Darbre, Nichollas E Scott, Jean-Louis Reymond, Anthony A Kossiakoff, Ethan D Goddard-Borger, Kaspar P Locher

Journal article  |  2023  |  NATURE CHEMICAL BIOLOGY

C-linked glycosylation is essential for the trafficking, folding and function of secretory and transmembrane proteins involved in ..

Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission (vol 13, 1400, 2022)

Sash Lopaticki, Robyn McConville, Alan John, Niall Geoghegan, Shihab Deen Mohamed, Lisa Verzier, Ryan WJ Steel, Cindy Evelyn, Matthew T O'Neill, Niccolay Madiedo Soler, Nichollas E Scott, Kelly L Rogers, Ethan D Goddard-Borger, Justin A Boddey

Journal article  |  2022  |  NATURE COMMUNICATIONS

The original version of this Article incorrectly cited reference 85 instead of reference 84 in the methods section ‘An. stephensi ..

Tryptophan C-mannosylation is critical for Plasmodium falciparum transmission

Sash Lopaticki, Robyn McConville, Alan John, Niall Geoghegan, Shihab Deen Mohamed, Lisa Verzier, Ryan WJ Steel, Cindy Evelyn, Matthew T O'Neill, Niccolay Madiedo Soler, Nichollas E Scott, Kelly L Rogers, Ethan D Goddard-Borger, Justin A Boddey

Journal article  |  2022  |  NATURE COMMUNICATIONS

Tryptophan C-mannosylation stabilizes proteins bearing a thrombospondin repeat (TSR) domain in metazoans. Here we show that Plasmo..

Chitin-Active Lytic Polysaccharide Monooxygenases Are Rare in Cellulomonas Species

James Li, Ethan D Goddard-Borger, Olanrewaju Raji, Hirak Saxena, Laleh Solhi, Yann Mathieu, Emma R Master, Warren W Wakarchuk, Harry Brumer

Journal article  |  2022  |  APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cellulomonas flavigena is a saprotrophic bacterium that encodes, within its genome, four predicted lytic polysaccharide monooxygen..

Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria

Mahima Sharma, James P Lingford, Marija Petricevic, Alexander JD Snow, Yunyang Zhang, Michael A Jarva, Janice W-Y Mui, Nichollas E Scott, Eleanor C Saunders, Ruwan Epa, Bruna M da Silva, Douglas EV Pires, David B Ascher, Malcolm J McConville, Gideon J Davies, Spencer J Williams, Ethan D Goddard-Borger

Journal article  |  2022  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catabolism of sulfoquinovose (SQ; 6-deoxy-6-sulfoglucose), the ubiquitous sulfosugar produced by photosynthetic organisms, is an i..

The sulfoquinovosyl glycerol binding protein SmoF binds and accommodates plant sulfolipids.

Alexander JD Snow, Mahima Sharma, James P Lingford, Yunyang Zhang, Janice W-Y Mui, Ruwan Epa, Ethan D Goddard-Borger, Spencer J Williams, Gideon J Davies

Journal article  |  2022  |  Curr Res Struct Biol

Sulfoquinovose (SQ) is the anionic headgroup of the ubiquitous plant sulfolipid, sulfoquinovosyl diacylglycerol (SQDG). SQDG can u..

Synthesis of C-Mannosylated Glycopeptides Enabled by Ni-Catalyzed Photoreductive Cross-Coupling Reactions

Runyu Mao, Shiyi Xi, Sayali Shah, Michael J Roy, Alan John, James P Lingford, Gerd Gade, Nichollas E Scott, Ethan D Goddard-Borger

Journal article  |  2021  |  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The biological functions of tryptophan C-mannosylation are poorly understood, in part, due to a dearth of methods for preparing pu..

NleB2 from enteropathogenic Escherichia coli is a novel arginine-glucose transferase effector

Cristina Giogha, Nichollas E Scott, Tania Wong Fok Lung, Georgina L Pollock, Marina Harper, Ethan D Goddard-Borger, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2021  |  PLOS PATHOGENS

During infection, enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli (EHEC) directly manipulate various aspec..