Vanessa Bryant

IL-17 production by tissue-resident MAIT cells is locally induced in children with pneumonia

Bingtai Lu, Ming Liu, Jun Wang, Huifeng Fan, Diyuan Yang, Li Zhang, Xiaoqiong Gu, Junli Nie, Zhenjun Chen, Alexandra J Corbett, Michael J Zhan, Shengbo Zhang, Vanessa L Bryant, Andrew M Lew, James McCluskey, Hai-bin Luo, Jun Cui, Yuxia Zhang, Yifan Zhan, Gen Lu

Journal article  |  2020  |  Mucosal Immunology

Community-acquired pneumonia (CAP) contributes substantially to morbidity and mortality in children under the age of 5 years. In e..

TCF-1 limits the formation of Tc17 cells via repression of the MAF-ROR gamma t axis

Lisa A Mielke, Yang Liao, Ella Bridie Clemens, Matthew A Firth, Brigette Duckworth, Qiutong Huang, Francisca F Almeida, Michael Chopin, Hui-Fern Koay, Carolyn A Bell, Soroor Hediyeh-Zadeh, Simone L Park, Dinesh Raghu, Jarny Choi, Tracy L Putoczki, Philip D Hodgkin, Ashley E Franks, Laura K Mackay, Dale Godfrey, Melissa J Davis, et al.

Journal article  |  2019  |  Journal of Experimental Medicine

Fatal Enteroviral Encephalitis in a Patient with Common Variable Immunodeficiency Harbouring a Novel Mutation in NFKB2

Charlotte A Slade, Catriona McLean, Thomas Scerri, Binh Giang Tran, Steven Megaloudis, Alexander Strathmore, Jessica C Tempany, Katherine Nicholls, Colleen D'Arcy, Melanie Bahlo, Philip D Hodgkin, Jo A Douglass, Vanessa L Bryant

Journal article  |  2019  |  Journal of Clinical Immunology

A Demonstration of the Diagnostic and Clinical Utility of Genomic Sequencing in Primary Immunodeficiency Diseases in Australia

Charlotte Slade, Fiona Moghaddas, Sebastian Lunke, Zornitza Stark, Ingrid Winship, Kirsty West, Alison Trainer, Samar Ojaimi, Matthew Hunter, Yael Prawer, Katherine Nicholls, Mittal Patel, Pricilla Auyeung, Kymble Spriggs, Jeremy McComish, Gary Unglik, Joseph De Luca, Samantha Chan, Giulia Valente, Anna Jarmolowicz, et al.

Conference Proceedings  |  2019  |  JOURNAL OF CLINICAL IMMUNOLOGY

Human IFN-gamma immunity to mycobacteria is governed by both IL-12 and IL-23

Ruben Martinez-Barricarte, Janet G Markle, Cindy S Ma, Elissa K Deenick, Noe Ramirez-Alejo, Federico Mele, Daniela Latorre, Seyed Alireza Mandaviani, Caner Aytekin, Davood Mansouri, Vanessa L Bryant, Fabienne Jabot-Hanin, Caroline Deswarte, Alejandro Nieto-Patlan, Laura Surace, Gaspard Kerner, Yuval Itan, Sandra Jovic, Danielle T Avery, Natalie Wong, et al.

Journal article  |  2018  |  Science Immunology

PITFALLS OF IMMUNOTHERAPY: LESSONS FROM A PATIENT WITH CTLA-4 HAPLOINSUFFICIENCY

Leisa R Watson, Charlotte A Slade, Samar Ojaimi, Sara Barnes, Pasquale Fedele, Prudence Smith, Justine Marum, Sebastian Lunke, Z Stark, Matthew F Hunter, Vanessa L Bryant, Michael SY Low

Conference Proceedings  |  2018  |  INTERNAL MEDICINE JOURNAL

Pitfalls of immunotherapy: lessons from a patient with CTLA-4 haploinsufficiency

Leisa Rebecca Watson, Charlotte A Slade, Samar Ojaimi, Sara Barnes, Pasquale Fedele, Prudence Smith, Justine Marum, Sebastian Lunke, Zornitza Stark, Matthew F Hunter, Vanessa L Bryant, Michael Sze Yuan Low

Journal article  |  2018  |  Allergy, Asthma & Clinical Immunology

The Rare Anaphylaxis-Associated Fc gamma RIIa3 Exhibits Distinct Characteristics From the Canonical Fc gamma RIIa1

Jessica C Anania, Halina M Trist, Catherine S Palmer, Peck Szee Tan, Betty P Kouskousis, Alicia M Chenoweth, Stephen J Kent, Graham A Mackay, Alberta Hoi, Rachel Koelmeyer, Charlotte Slade, Vanessa L Bryant, Philip D Hodgkin, Pei Mun Aui, Menno C van Zelm, Bruce D Wines, P Mark Hogarth

Journal article  |  2018  |  Frontiers in Immunology

Delayed Diagnosis and Complications of Predominantly Antibody Deficiencies in a Cohort of Australian Adults

Charlotte A Slade, Julian J Bosco, Tran Binh Giang, Elizabeth Kruse, Robert G Stirling, Paul U Cameron, Fiona Hore-Lacy, Michael F Sutherland, Sara L Barnes, Stephen Holdsworth, Samar Ojaimi, Gary A Unglik, Joseph De Luca, Mittal Patel, Jeremy McComish, Kymble Spriggs, Yang Tran, Priscilla Auyeung, Katherine Nicholls, Robyn E O'Hehir, et al.

Journal article  |  2018  |  Frontiers in Immunology

Review: Diagnosing Common Variable Immunodeficiency Disorder in the Era of Genome Sequencing

Rohan Ameratunga, Klaus Lehnert, See-Tarn Woon, David Gillis, Vanessa L Bryant, Charlotte A Slade, Richard Steele

Journal article  |  2018  |  Clinical Reviews in Allergy & Immunology

Superior properties of CellTrace Yellow (TM) as a division tracking dye for human and murine lymphocytes

Jessica C Tempany, Jie HS Zhou, Philip D Hodgkin, Vanessa L Bryant

Journal article  |  2018  |  Immunology and Cell Biology

Clinical Implications of Digenic Inheritance and Epistasis in Primary Immunodeficiency Disorders

Rohan Ameratunga, See-Tarn Woon, Vanessa L Bryant, Richard Steele, Charlotte Slade, Euphemia Yee Leung, Klaus Lehnert

Journal article  |  2018  |  Frontiers in Immunology

Epistatic interactions between mutations of TACI (TNFRSF13B) and TCF3 result in a severe primary immunodeficiency disorder and systemic lupus erythematosus

Rohan Ameratunga, Wikke Koopmans, See-Tarn Woon, Euphemia Leung, Klaus Lehnert, Charlotte A Slade, Jessica C Tempany, Anselm Enders, Richard Steele, Peter Browett, Philip D Hodgkin, Vanessa L Bryant

Journal article  |  2017  |  Clinical & Translational Immunology

IMMUNOLOGY Life, death, and antibodies

Vanessa L Bryant, Philip D Hodgkin

Journal article  |  2017  |  Science

Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation

Simona Infantino, Amanda Light, Kristy O'Donnell, Vanessa Bryant, Danielle T Avery, Michael Elliott, Stuart G Tangye, Gabrielle Belz, Fabienne Mackay, Stephane Richard, David Tarlinton

Journal article  |  2017  |  Nature Communications

The TNF Receptor Superfamily-NF-kappa B Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues

Ajithkumar Vasanthakumar, Yang Liao, Peggy Teh, Maria F Pascutti, Anna E Oja, Alexandra L Garnham, Renee Gloury, Jessica C Tempany, Tom Sidwell, Eloy Cuadrado, Paul Tuijnenburg, Taco W Kuijpers, Najoua Lalaoui, Lisa A Mielke, Vanessa L Bryant, Philip D Hodgkin, John Silke, Gordon K Smyth, Martijn A Nolte, Wei Shi, et al.

Journal article  |  2017  |  Cell Reports

The Expanding Spectrum of NFkB1 Deficiency

Vanessa L Bryant, Stuart G Tangye

Journal article  |  2016  |  Journal of Clinical Immunology

Haploinsufficiency of the NF-kappa B1 Subunit p50 in Common Variable Immunodeficiency

Manfred Fliegauf, Vanessa L Bryant, Natalie Frede, Charlotte Slade, See-Tarn Woon, Klaus Lehnert, Sandra Winzer, Alla Bulashevska, Thomas Scerri, Euphemia Leung, Anthony Jordan, Baerbel Keller, Esther de Vries, Hongzhi Cao, Fang Yang, Alejandro A Schaeffer, Klaus Warnatz, Peter Browett, Jo Douglass, Rohan V Ameratunga, et al.

Journal article  |  2015  |  The American Journal of Human Genetics

Chemokines, their receptors and human disease: the good, the bad and the itchy

Vanessa L Bryant, Charlotte A Slade

Journal article  |  2015  |  Immunology & Cell Biology

Simple diagnosis of STAT1 gain-of-function alleles in patients with chronic mucocutaneous candidiasis.

Yoko Mizoguchi, Miyuki Tsumura, Satoshi Okada, Osamu Hirata, Shizuko Minegishi, Kohsuke Imai, Nobuyuki Hyakuna, Hideki Muramatsu, Seiji Kojima, Yusuke Ozaki, Takehide Imai, Sachiyo Takeda, Tetsuya Okazaki, Tsuyoshi Ito, Shin'ichiro Yasunaga, Yoshihiro Takihara, Vanessa L Bryant, Xiao-Fei Kong, Sophie Cypowyj, Stéphanie Boisson-Dupuis, et al.

Journal article  |  2014  |  Journal of Leukocyte Biology

CMCD is a rare congenital disorder characterized by persistent or recurrent skin, nail, and mucosal membrane infections caused by ..

Partial IFN-γR2 deficiency is due to protein misfolding and can be rescued by inhibitors of glycosylation.

Marcela Moncada-Vélez, Rubén Martinez-Barricarte, Dusan Bogunovic, Xiao-Fei Kong, Lizbeth Blancas-Galicia, Cengiz Tirpan, Guzide Aksu, Quentin B Vincent, Bertrand Boisson, Yuval Itan, Noé Ramírez-Alejo, Satoshi Okada, Alexandra Y Kreins, Vanessa L Bryant, Jose Luis Franco, Mélanie Migaud, Sara Espinosa-Padilla, Marco Yamazaki-Nakashimada, Francisco Espinosa-Rosales, Necil Kutukculer, et al.

Journal article  |  2013  |  Blood

We report a molecular study of the two known patients with autosomal recessive, partial interferon-γ receptor (IFN-γR)2 deficiency..

Haploinsufficiency at the human IFNGR2 locus contributes to mycobacterial disease.

Xiao-Fei Kong, Guillaume Vogt, Yuval Itan, Anna Macura-Biegun, Anna Szaflarska, Danuta Kowalczyk, Ariane Chapgier, Avinash Abhyankar, Dieter Furthner, Claudia Djambas Khayat, Satoshi Okada, Vanessa L Bryant, Dusan Bogunovic, Alexandra Kreins, Marcela Moncada-Vélez, Mélanie Migaud, Sulaiman Al-Ajaji, Saleh Al-Muhsen, Steven M Holland, Laurent Abel, et al.

Journal article  |  2013  |  Human Molecular Genetics

Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare syndrome, the known genetic etiologies of which impair the pro..

A novel homozygous p.R1105X mutation of the AP4E1 gene in twins with hereditary spastic paraplegia and mycobacterial disease.

Xiao-Fei Kong, Aziz Bousfiha, Abdelfettah Rouissi, Yuval Itan, Avinash Abhyankar, Vanessa Bryant, Satoshi Okada, Fatima Ailal, Jacinta Bustamante, Jean-Laurent Casanova, Jennifer Hirst, Stéphanie Boisson-Dupuis

Journal article  |  2013  |  PLoS ONE

We report identical twins with intellectual disability, progressive spastic paraplegia and short stature, born to a consanguineous..

Mycobacterial disease and impaired IFN-γ immunity in humans with inherited ISG15 deficiency

D Bogunovic, M Byun, LA Durfee, A Abhyankar, O Sanal, D Mansouri, S Salem, I Radovanovic, AV Grant, P Adimi, N Mansouri, S Okada, VL Bryant, XF Kong, A Kreins, MM Velez, B Boisson, S Khalilzadeh, U Ozcelik, IA Darazam, et al.

Journal article  |  2012  |  Science

A novel form of human STAT1 deficiency impairing early but not late responses to interferons.

Xiao-Fei Kong, Michael Ciancanelli, Sami Al-Hajjar, Laia Alsina, Timothy Zumwalt, Jacinta Bustamante, Jacqueline Feinberg, Magali Audry, Carolina Prando, Vanessa Bryant, Alexandra Kreins, Dusan Bogunovic, Rabih Halwani, Xin-Xin Zhang, Laurent Abel, Damien Chaussabel, Saleh Al-Muhsen, Jean-Laurent Casanova, Stéphanie Boisson-Dupuis

Journal article  |  2010  |  Blood

Autosomal recessive STAT1 deficiency is associated with impaired cellular responses to interferons and susceptibility to intracell..

STAT3 is required for IL-21-induced secretion of IgE from human naive B cells.

Danielle T Avery, Cindy S Ma, Vanessa L Bryant, Brigitte Santner-Nanan, Ralph Nanan, Melanie Wong, David A Fulcher, Matthew C Cook, Stuart G Tangye

Journal article  |  2008  |  Blood

The production of immunoglobulin E (IgE) is tightly regulated. This is evidenced by the fact that it comprises less than 0.0001% o..

IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4.

Danielle T Avery, Vanessa L Bryant, Cindy S Ma, Rene de Waal Malefyt, Stuart G Tangye

Journal article  |  2008  |  The Journal of Immunology

Naive B cells can alter the effector function of their Ig molecule by isotype switching, thereby allowing them to secrete not only..

Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5( ) T follicular helper cells

Vanessa L Bryant, Cindy S Ma, Danielle T Avery, Ying Li, Kim L Good, Lynn M Corcoran, Rene de Waal Malefyt, Stuart G Tangye

Journal article  |  2007  |  The Journal of Immunology

Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.

Kim L Good, Vanessa L Bryant, Stuart G Tangye

Journal article  |  2006  |  The Journal of Immunology

Although recent studies indicated that IL-21 is an important regulator of human B cell activation, detailed comparison of the effe..

BAFF, APRIL and human B cell disorders.

Stuart G Tangye, Vanessa L Bryant, Amanda K Cuss, Kim L Good

Journal article  |  2006  |  Seminars in Immunology

B cells require signals from multiple sources for their development from precursor cells, and differentiation into effector cells...