Joe Byrne

High-Throughput Phenotypic Assay to Screen for Anthelmintic Activity on Haemonchus contortus.

Aya C Taki, Joseph J Byrne, Tao Wang, Brad E Sleebs, Nghi Nguyen, Ross S Hall, Pasi K Korhonen, Bill CH Chang, Paul Jackson, Abdul Jabbar, Robin B Gasser

Journal article  |  2021  |  Pharmaceuticals (Basel)

Parasitic worms cause very significant diseases in animals and humans worldwide, and their control is critical to enhance health, ..

Three Small Molecule Entities (MPK18, MPK334 and YAK308) with Activity against Haemonchus contortus In Vitro

Aya C Taki, Abdul Jabbar, Thomas Kurz, Beate Lungerich, Guangxu Ma, Joseph J Byrne, Marc Pflieger, Yodita Asfaha, Fabian Fischer, Bill CH Chang, Brad E Sleebs, Robin B Gasser

Journal article  |  2021  |  MOLECULES

Due to widespread multi-drug resistance in parasitic nematodes of livestock animals, there is an urgent need to discover new anthe..

Practical High-Throughput Method to Screen Compounds for Anthelmintic Activity against Caenorhabditis elegans

Aya C Taki, Joseph J Byrne, Peter R Boag, Abdul Jabbar, Robin B Gasser

Journal article  |  Molecules

In the present study, we established a practical and cost-effective high throughput screening assay, which relies on the measureme..