Toby Mansell

Age-dependent associations of human milk oligosaccharides with body size and composition up to 4 years of age.

Toby Mansell, Annalee Furst, Martin O'Hely, Melinda Chang, Anne-Louise Ponsonby, Peter Vuillermin, Mimi Lk Tang, David Burgner, Richard Saffery, Lars Bode, undefined Barwon Infant Study Investigator Group

Journal article  |  2023  |  Am J Clin Nutr

BACKGROUND: Human milk oligosaccharides (HMOs) are major components of human milk that may mediate its beneficial effects on infan..

Long-term cardiometabolic health in people born after assisted reproductive technology: a multi-cohort analysis

Ahmed Elhakeem, Amy E Taylor, Hazel M Inskip, Jonathan Y Huang, Toby Mansell, Carina Rodrigues, Federica Asta, Sophia M Blaauwendraad, Siri E Haberg, Jane Halliday, Margreet W Harskamp-van Ginkel, Jian-Rong He, Vincent WV Jaddoe, Sharon Lewis, Gillian M Maher, Yannis Manios, Fergus P McCarthy, Irwin KM Reiss, Franca Rusconi, Theodosia Salika, et al.

Journal article  |  2023  |  EUROPEAN HEART JOURNAL

AIMS: To examine associations of assisted reproductive technology (ART) conception (vs. natural conception: NC) with offspring car..

Effect of common pregnancy and perinatal complications on offspring metabolic traits across the life course: a multi-cohort study

Ahmed Elhakeem, Justiina Ronkainen, Toby Mansell, Katherine Lange, Tuija MM Mikkola, Binisha HH Mishra, Rama JJ Wahab, Tim Cadman, Tiffany Yang, David Burgner, Johan GG Eriksson, Marjo-Riitta Jaervelin, Romy Gaillard, Vincent WV Jaddoe, Terho Lehtimaeki, Olli TT Raitakari, Richard Saffery, Melissa Wake, John Wright, Sylvain Sebert, et al.

Journal article  |  2023  |  BMC MEDICINE

BACKGROUND: Common pregnancy and perinatal complications are associated with offspring cardiometabolic risk factors. These complic..

In-utero HIV exposure and cardiometabolic health among children 5-8 years: findings from a prospective birth cohort in South Africa.

Angela M Bengtson, Jennifer Pellowski, Stephen McGarvey, Rae McGinty, Maresa Botha, Tiffany Burd, David Burgner, Toby Mansell, Heather J Zar

Journal article  |  2023  |  AIDS

OBJECTIVE: To evaluate if in-utero HIV exposure is associated with adverse cardiometabolic health outcomes at 5-8 years of age. DE..

Increased maternal non-oxidative energy metabolism mediates association between prenatal di-(2-ethylhexyl) phthalate (DEHP) exposure and offspring autism spectrum disorder symptoms in early life: A birth cohort study

Sarah Thomson, Katherine Drummond, Martin O'Hely, Christos Symeonides, Chitra Chandran, Toby Mansell, Richard Saffery, Peter Sly, Jochen Mueller, Peter Vuillermin, Anne-Louise Ponsonby, Infant Study Investigator Group Barwon

Journal article  |  2022  |  ENVIRONMENT INTERNATIONAL

Prenatal phthalate exposure has previously been linked to the development of autism spectrum disorder (ASD). However, the underlyi..

Gender-affirming hormone therapy induces specific DNA methylation changes in blood

Rebecca Shepherd, Ingrid Bretherton, Ken Pang, Anna Czajko, Bowon Kim, Amanda Vlahos, Jeffrey D Zajac, Richard Saffery, Ada Cheung, Boris Novakovic, Toby Manse

Journal article  |  2022  |  CLINICAL EPIGENETICS

BACKGROUND: DNA methylation is an epigenetic mark that is influenced by underlying genetic profile, environment, and ageing. In ad..

A novel role of FoxO3a in the migration and invasion of trophoblast cells: from metabolic remodeling to transcriptional reprogramming

Hao Chen, Shi-Han Wang, Chang Chen, Xin-Yang Yu, Jia-Nan Zhu, Toby Mansell, Boris Novakovic, Richard Saffery, Philip N Baker, Ting-Li Han, Hua Zhang

Journal article  |  2022  |  MOLECULAR MEDICINE

BACKGROUND: The forkhead box O3a protein (FoxO3a) has been reported to be involved in the migration and invasion of trophoblast, b..

EARLY LIFE INFECTION IS ASSOCIATED WITH PROINFLAMMATORY, ATHEROGENIC, AND DIABETOGENIC METABOLOMIC AND LIPIDOMIC PROFILES AT 12 MONTHS OF AGE

D Burgner, T Mansell, R Saffery, S Burugupalli, A-L Ponsonby, M Tang, M O'Hely, S Bekkering, A Smith, R Rowland, S Ranganathan, P Sly, P Vuillermin, F Collier, P Meikle

Journal article  |  2022  |  ATHEROSCLEROSIS

GlycA but not CRP is an inflammatory biomarker of longitudinal changes in BMI and adiposity in adolescents with obesity

T Mansell, S Bekkering, CG Magnussen, A Vlahos, B Harcourt, Z Mccallum, K-T Kao, MA Sabin, M Juonala, R Saffery, D Burgner, C Saner

Journal article  |  2022  |  Atherosclerosis

Association of Assisted Reproductive Technology With Offspring Growth and Adiposity From Infancy to Early Adulthood

Ahmed Elhakeem, Amy E Taylor, Hazel M Inskip, Jonathan Huang, Muriel Tafflet, Johan L Vinther, Federica Asta, Jan S Erkamp, Luigi Gagliardi, Kathrin Guerlich, Jane Halliday, Margreet W Harskamp-van Ginkel, Jian-Rong He, Vincent WV Jaddoe, Sharon Lewis, Gillian M Maher, Yannis Manios, Toby Mansell, Fergus P McCarthy, Sheila W McDonald, et al.

Journal article  |  2022  |  JAMA NETWORK OPEN

IMPORTANCE: People conceived using assisted reproductive technology (ART) make up an increasing proportion of the world's populati..