Steven Bozinovski

Sensitive molecular testing methods can demonstrate NSCLC driver mutations in malignant pleural effusion despite nonmalignant cytology

Daniel P Steinfort, Sevastjan Kranz, Anthony Dowers, Leakhena Leas, Voula Dimitriadis, Kym Pham, Arthur Hsu, Steven Bozinovski, Louis B Irving, Paula Loveland, Michael Christie

Journal article  |  2019  |  Translational Lung Cancer Research

Novel multiplex droplet digital PCR assay for scoring PD-L1 in non-small cell lung cancer biopsy specimens

Amanda Vannitamby, Shona Hendry, Louis Irving, Daniel Steinfort, Steven Bozinovski

Journal article  |  2019  |  Lung Cancer

Excessive Reactive Oxygen Species Inhibit IL-17A( ) gamma delta T Cells and Innate Cellular Responses to Bacterial Lung Infection

Desiree Anthony, Angelica Papanicolaou, Hao Wang, Huei Jiunn Seow, Eunice E To, Selcuk Yatmaz, Gary P Anderson, Odilia Wijburg, Stavros Selemidis, Ross Vlahos, Steven Bozinovski

Journal article  |  2019  |  Antioxidants & Redox Signaling

In vivo imaging of brain muscarinic receptors with F-18 Flurobenzyl Dexetimide: First in human studies

Christopher Rowe, Brian Dean, Uwe Ackermann, Rachel Goh, Rodney Guzman, Richard Kanaan, Lee Chong, Vincent Dore, Svetlana Bozinovski, Colin Masters, Victor Villemagne

Conference Proceedings  |  2019  |  JOURNAL OF NUCLEAR MEDICINE

A Novel Approach to Detect Programed Death Ligand 1 (PD-L1) Status and Multiple Tumor Mutations Using a Single Non-Small-Cell Lung Cancer (NSCLC) Bronchoscopy Specimen

Amanda Vannitamby, Shona Hendry, Tanvi Makadia, Janine Danks, John Slavin, Louis Irving, Daniel Steinfort, Steven Bozinovski

Journal article  |  2019  |  The Journal of Molecular Diagnostics

CSF3R/CD114 mediates infection-dependent transition to severe asthma

Hao Wang, Meaghan FitzPatrick, Nicholas J Wilson, Desiree Anthony, Patrick C Reading, Catherine Satzke, Eileen M Dunne, Paul V Licciardi, Huei Jiunn Seow, Kristy Nichol, Ian M Adcock, Kian Fan Chung, Gary P Anderson, Ross Vlahos, Peter Wark, Steven Bozinovski

Journal article  |  2019  |  Journal of Allergy and Clinical Immunology

The transcriptomic response of Streptococcus pneumoniae following exposure to cigarette smoke extract

Sam Manna, Alicia Waring, Angelica Papanicolaou, Nathan E Hall, Steven Bozinovski, Eileen M Dunne, Catherine Satzke

Journal article  |  2018  |  Scientific Reports

Increased hypothalamic microglial activation after viral-induced pneumococcal lung infection is associated with excess serum amyloid A production.

Hao Wang, Melissa Blackall, Luba Sominsky, Sarah J Spencer, Ross Vlahos, Melissa Churchill, Steven Bozinovski

Journal article  |  2018  |  Journal of Neuroinflammation

BACKGROUND: It is well established that lung pathology and inflammation are more severe during respiratory infections complicated ..

ANTI G-CSFR ANTIBODY TREATMENT SUPPRESSES NEUTROPHILIC AND TYPE-2 LUNG INFLAMMATION IN AN ALLERGIC ASTHMA MODEL WORSENED BY NEONATAL CO-INFECTION

H Wang, M Fitzpatrick, D Anthony, P Reading, N Wilson, C Satzke, E Dunne, P Licciardi, G Anderson, R Vlahos, S Bozinovski

Conference Proceedings  |  2018  |  RESPIROLOGY

Protocols to Evaluate Cigarette Smoke-Induced Lung Inflammation and Pathology in Mice.

Ross Vlahos, Steven Bozinovski

Book Chapter  |  2018  |  Methods in Molecular Biology

Cigarette smoking is a major cause of chronic obstructive pulmonary disease (COPD). Inhalation of cigarette smoke causes inflammat..

Tumour-associated neutrophils and loss of epithelial PTEN can promote corticosteroid-insensitive MMP-9 expression in the chronically inflamed lung microenvironment

Amanda Vannitamby, Huei Jiunn Seow, Gary Anderson, Ross Vlahos, Michelle Thompson, Daniel Steinfort, Louis B Irving, Steven Bozinovski

Journal article  |  2017  |  Thorax

Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema

Saleela M Ruwanpura, Louise McLeod, Lovisa F Dousha, Huei J Seow, Sultan Alhayyani, Michelle D Tate, Virginie Deswaerte, Gavin D Brooks, Steven Bozinovski, Martin MacDonald, Christoph Garbers, Paul T King, Philip G Bardin, Ross Vlahos, Stefan Rose-John, Gary P Anderson, Brendan J Jenkins

Journal article  |  2016  |  American Journal of Respiratory and Critical Care Medicine

Emerging therapies for the treatment of skeletal muscle wasting in chronic obstructive pulmonary disease

Samantha L Passey, Michelle J Hansen, Steven Bozinovski, Christine F McDonald, Anne E Holland, Ross Vlahos

Journal article  |  2016  |  Pharmacology & Therapeutics

COPD and stroke: are systemic inflammation and oxidative stress the missing links?

Victoria Austin, Peter J Crack, Steven Bozinovski, Alyson A Miller, Ross Vlahos

Journal article  |  2016  |  Clinical Science

Neonatal pneumococcal colonisation caused by Influenza A infection alters lung function in adult mice

Meaghan FitzPatrick, Simon G Royce, Shenna Langenbach, Jonathan McQualter, Patrick C Reading, Odilia Wijburg, Gary P Anderson, Alastair Stewart, Jane Bourke, Steven Bozinovski

Journal article  |  2016  |  Scientific Reports

Apocynin and ebselen reduce influenza A virus-induced lung inflammation in cigarette smoke-exposed mice

LC Oostwoud, P Gunasinghe, HJ Seow, JM Ye, S Selemidis, S Bozinovski, R Vlahos

Journal article  |  2016  |  Scientific Reports

COPD and squamous cell lung cancer: aberrant inflammation and immunity is the common link

Steven Bozinovski, Ross Vlahos, Desiree Anthony, Jonathan McQualter, Gary Anderson, Louis Irving, Daniel Steinfort

Journal article  |  2016  |  British Journal of Pharmacology

Serum Amyloid A Induces Toll-Like Receptor 2-Dependent Inflammatory Cytokine Expression and Atrophy in C2C12 Skeletal Muscle Myotubes

Samantha L Passey, Steven Bozinovski, Ross Vlahos, Gary P Anderson, Michelle J Hansen

Journal article  |  2016  |  PLOS ONE

Do anti-viral neutrophil responses exacerbate lung inflammation in asthma?

Ross Vlahos, Steven Bozinovski

Journal article  |  2016  |  Respirology

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette-smoke-induced lung inflammation in mice

Steven Bozinovski, Huei Jiunn Seow, Sheau Pyng Jamie Chan, Desiree Anthony, Jonathan McQualter, Michelle Hansen, Brendan J Jenkins, Gary P Anderson, Ross Vlahos

Journal article  |  2015  |  Clinical Science

Targeting oxidant-dependent mechanisms for the treatment of COPD and its comorbidities

Ivan Bernardo, Steven Bozinovski, Ross Vlahos

Journal article  |  2015  |  Pharmacology & Therapeutics

Preclinical murine models of Chronic Obstructive Pulmonary Disease

Ross Vlahos, Steven Bozinovski

Journal article  |  2015  |  European Journal of Pharmacology

Multifaceted Role for 1L-17A in the Pathogenesis of Chronic Obstructive Pulmonary Disease

Steven Bozinovski, Ross Vlahos

Journal article  |  2015  |  American Journal of Respiratory and Critical Care Medicine

Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis

Gareth W Jones, Louise McLeod, Catherine L Kennedy, Steven Bozinovski, Meri Najdovska, Brendan J Jenkins

Journal article  |  2015  |  Atherosclerosis

HSP90 Inhibition Suppresses Lipopolysaccharide-Induced Lung Inflammation In Vivo

Andrew Lilja, Clare E Weeden, Kate McArthur, Nguyen Thao, Alastair Donald, Zi Xin Wong, Lovisa Dousha, Steve Bozinovski, Ross Vlahos, Christopher J Burns, Marie-Liesse Asselin-Labat, Gary P Anderson

Journal article  |  2015  |  PLOS ONE

IL-17A and Serum Amyloid A Are Elevated in a Cigarette Smoke Cessation Model Associated with the Persistence of Pigmented Macrophages, Neutrophils and Activated NK Cells

Michelle J Hansen, Sheau Pyng J Chan, Shenna Y Langenbach, Lovisa F Dousha, Jessica E Jones, Selcuk Yatmaz, Huei Jiunn Seow, Ross Vlahos, Gary P Anderson, Steven Bozinovski

Journal article  |  2014  |  PLoS ONE

Targeting pro-resolution pathways to combat chronic inflammation in COPD

Steven Bozinovski, Desiree Anthony, Ross Vlahos

Journal article  |  2014  |  Journal of Thoracic Disease

Harnessing the potential of lung stem cells for regenerative medicine

Jonathan L McQualter, Desiree Anthony, Steven Bozinovski, Cecilia M Prele, Geoffrey J Laurent

Journal article  |  2014  |  The International Journal of Biochemistry & Cell Biology

Role of alveolar macrophages in chronic obstructive pulmonary disease

Ross Vlahos, Steven Bozinovski

Journal article  |  2014  |  Frontiers in Immunology

SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling

Desiree Anthony, Jonathan L McQualter, Maria Bishara, Ee X Lim, Selcuk Yatmaz, Huei Jiunn Seow, Michelle Hansen, Michelle Thompson, John A Hamilton, Louis B Irving, Bruce D Levy, Ross Vlahos, Gary P Anderson, Steven Bozinovski

Journal article  |  2014  |  The FASEB Journal

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice

Saleela M Ruwanpura, Louise McLeod, Gavin D Brooks, Steven Bozinovski, Ross Vlahos, Anthony Longano, Philip G Bardin, Gary P Anderson, Brendan J Jenkins

Journal article  |  2014  |  Respirology

Recent advances in pre-clinical mouse models of COPD

Ross Vlahos, Steven Bozinovski

Journal article  |  2014  |  Clinical Science

Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways

Steven Bozinovski, Desiree Anthony, Gary P Anderson, Louis B Irving, Bruce D Levy, Ross Vlahos

Journal article  |  2013  |  Pharmacology and Therapeutics

TGF-beta signaling in stromal cells acts upstream of FGF-10 to regulate epithelial stem cell growth in the adult lung

Jonathan L McQualter, Rosa C McCarty, Joanne Van der Velden, Robert JJ O'Donoghu, Marie-Liesse Asselin-Labat, Steven Bozinovski, Ivan Bertoncello

Journal article  |  2013  |  Stem Cell Research

Non-Essential Role for TLR2 and Its Signaling Adaptor Mal/TIRAP in Preserving Normal Lung Architecture in Mice

Saleela M Ruwanpura, Louise McLeod, Andrew R Lilja, Gavin Brooks, Lovisa F Dousha, Huei J Seow, Steven Bozinovski, Ross Vlahos, Paul J Hertzog, Gary P Anderson, Brendan J Jenkins

Journal article  |  2013  |  PLoS One

Increase in Net Activity of Serine Proteinases but Not Gelatinases after Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects

Margaretha E Smith, Steven Bozinovski, Carina Malmhall, Margareta Sjostrand, Pernilla Glader, Per Venge, Pieter S Hiemstra, Gary P Anderson, Anders Linden, Ingemar Qvarfordt

Journal article  |  2013  |  PLoS One

Serum Amyloid A Promotes Lung Neutrophilia by Increasing IL-17A Levels in the Mucosa and gamma delta T Cells

Desiree Anthony, Huei Jiunn Seow, Mohib Uddin, Michelle Thompson, Lovisa Dousha, Ross Vlahos, Louis B Irving, Bruce D Levy, Gary P Anderson, Steven Bozinovski

Journal article  |  2013  |  American Journal of Respiratory and Critical Care Medicine

Glutathione peroxidase-1 as a novel therapeutic target for COPD

Ross Vlahos, Steven Bozinovski

Journal article  |  2013  |  Redox Report

Nox1 Oxidase Suppresses Influenza A Virus-Induced Lung Inflammation and Oxidative Stress

Stavros Selemidis, Huei Jiunn Seow, Brad RS Broughton, Antony Vinh, Steven Bozinovski, Christopher G Sobey, Grant R Drummond, Ross Vlahos

Journal article  |  2013  |  PLoS One

Glutathione Peroxidase-1 Reduces Influenza A Virus-Induced Lung Inflammation

Selcuk Yatmaz, Huei Jiunn Seow, Rosa C Gualano, Zi Xin Wong, John Stambas, Stavros Selemidis, Peter J Crack, Steven Bozinovski, Gary P Anderson, Ross Vlahos

Journal article  |  2013  |  American Journal of Respiratory Cell and Molecular Biology

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

Robert JJ O'Donoghue, Darryl A Knight, Carl D Richards, Cecilia M Prele, Hui Ling Lau, Andrew G Jarnicki, Jessica Jones, Steven Bozinovski, Ross Vlahos, Stefan Thiem, Brent S McKenzie, Bo Wang, Philip Stumbles, Geoffrey J Laurent, Robin J McAnulty, Stefan Rose-John, Hong Jian Zhu, Gary P Anderson, Matthias R Ernst, Steven E Mutsaers

Journal article  |  2012  |  EMBO Molecular Medicine

INHIBITION OF NOX1 OXIDASE EXACERBATES INFLUENZA A VIRUS-INDUCED LUNG INFLAMMATION.

Stavros Selemidis, Huei Juinn Seow, Brad Broughton, Steven Bozinovski, Antony Vinh, John Stambas, Christopher Sobey, Grant Drummond, Ross Vlahos

Conference Proceedings  |  2012  |  The FASEB JOURNAL

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice

Saleela M Ruwanpura, Louise McLeod, Alistair Miller, Jessica Jones, Ross Vlahos, Georg Ramm, Anthony Longano, Philip G Bardin, Steven Bozinovski, Gary P Anderson, Brendan J Jenkins

Journal article  |  2012  |  American Journal of Physiology - Lung Cellular and Molecular Physiology

Glucocorticosteroids Differentially Regulate MMP-9 and Neutrophil Elastase in COPD

Ross Vlahos, Peter AB Wark, Gary P Anderson, Steven Bozinovski

Journal article  |  2012  |  PLoS One

Glutathione Peroxidase-1 Primes Pro-Inflammatory Cytokine Production after LPS Challenge In Vivo

Steven Bozinovski, Huei Jiunn Seow, Peter J Crack, Gary P Anderson, Ross Vlahos

Journal article  |  2012  |  PLoS One

Serum amyloid A opposes lipoxin A(4) to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

Steven Bozinovski, Mohib Uddin, Ross Vlahos, Michelle Thompson, Jonathan L McQualter, Anne-Sophie Merritt, Peter AB Wark, Anastasia Hutchinson, Louis B Irving, Bruce D Levy, Gary P Anderson

Journal article  |  2012  |  Proceedings of the National Academy of Sciences of the United States of America

Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

S Bozinovski, undefined Uddin, RV Vlahos, undefined Thompson, JL Mcqualter, undefined Merritt, B Wark, undefined Hutchinson, LB Irving, GP Anderson

Journal article  |  2012  |  Proceedings of the National Academy of Sciences of the United States of America

Interleukin-6 Promotes Pulmonary Emphysema Associated with Apoptosis in Mice

Saleela M Ruwanpura, Louise McLeod, Alistair Miller, Jessica Jones, Steven Bozinovski, Ross Vlahos, Matthias Ernst, Jane Armes, Philip G Bardin, Gary P Anderson, Brendan J Jenkins

Journal article  |  2011  |  American Journal of Respiratory Cell and Molecular Biology

Carbonylation Caused by Cigarette Smoke Extract Is Associated with Defective Macrophage Immunity

Steven Bozinovski, Ross Vlahos, Yilin Zhang, Lin Chin Lah, Huei Jiunn Seow, Ashley Mansell, Gary P Anderson

Journal article  |  2011  |  American Journal of Respiratory Cell and Molecular Biology

Inhibition of Nox2 Oxidase Activity Ameliorates Influenza A Virus-Induced Lung Inflammation

Ross Vlahos, John Stambas, Steven Bozinovski, Brad RS Broughton, Grant R Drummond, Stavros Selemidis

Journal article  |  2011  |  PLoS Pathogens

Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice

Chi Duong, Huei Jiunn Seow, Steven Bozinovski, Peter J Crack, Gary P Anderson, Ross Vlahos

Journal article  |  2010  |  American Journal of Physiology - Lung Cellular and Molecular Physiology

Neutralizing Granulocyte/Macrophage Colony-Stimulating Factor Inhibits Cigarette Smoke-induced Lung Inflammation

Ross Vlahos, Steven Bozinovski, Sheau Pyng Jamie Chan, Stefan Ivanov, Anders Linden, John A Hamilton, Gary P Anderson

Journal article  |  2010  |  American Journal of Respiratory and Critical Care Medicine

Increased net gelatinase but not serine protease activity in bronchiolitis obliterans syndrome

Gerdt C Riise, Petrea Ericson, Steven Bozinovski, Shigemi Yoshihara, Gary P Anderson, Anders Linden

Journal article  |  2010  |  Journal of Heart and Lung Transplantation

Identifying viral infections in vaccinated Chronic Obstructive Pulmonary Disease (COPD) patients using clinical features and inflammatory markers

Anastasia F Hutchinson, Jim Black, Michelle A Thompson, Steven Bozinovski, Caroline A Brand, David M Smallwood, Louis B Irving, Gary P Anderson

Journal article  |  2010  |  Influenza and Other Respiratory Viruses

IL-17-producing T lymphocytes in lung tissue and in the bronchoalveolar space after exposure to endotoxin from Escherichia coli in vivo - effects of anti-inflammatory pharmacotherapy

Olof Prause, Apostolos Bossios, Elin Silverpil, Stefan Ivanov, Steven Bozinovski, Ross Vlahos, Margareta Sjostrand, Gary P Anderson, Anders Linden

Journal article  |  2009  |  Pulmonary Pharmacology and Therapeutics

Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

Connie HY Wong, Steven Bozinovski, Paul J Hertzog, Michael J Hickey, Peter J Crack

Journal article  |  2008  |  Journal of Neurochemistry

DNA vector augments inflammation in epithelial cells via EGFR-dependent regulation of TLR4 and TLR2

Kenneth Liu, Gary P Anderson, Steven Bozinovski

Journal article  |  2008  |  American Journal of Respiratory Cell and Molecular Biology

Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space

P Glader, B Eldh, S Bozinovski, K Andelid, M Sjostrand, C Malmhall, GP Anderson, GC Riise, I Qvarfordt, A Linden

Journal article  |  2008  |  European Respiratory Journal

Epidermal growth factor receptor signaling to Erk1/2 and STATs control the intensity of the epithelial inflammatory responses to rhinovirus infection

Kenneth Liu, Rosa C Gualano, Margaret L Hibbs, Gary P Anderson, Steven Bozinovski

Journal article  |  2008  |  Journal of Biological Chemistry

Serum amyloid A is a biomarker of acute exacerbations of chronic obstructive pulmonary disease

Steven Bozinovski, Anastasia Hutchinson, Michelle Thompson, Lochlan MacGregor, James Black, Eleni Giannakis, Anne-Sophie Karlsson, Roger Silvestrini, David Smallwood, Ross Vlahos, Louis B Irving, Gary P Anderson

Journal article  |  2008  |  American Journal of Respiratory and Critical Care Medicine

A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD

Anastasia F Hutchinson, Anil K Ghimire, Michelle A Thompson, Jim F Black, Caroline A Brand, Adrian J Lowe, David M Smallwood, Ross Vlahos, Steven Bozinovski, Graham V Brown, Gary P Anderson, Louis B Irving

Journal article  |  2007  |  Respiratory Medicine

Functional relevance of the IL-23-IL-17 axis in lungs in vivo

Stefan Ivanov, Steven Bozinovski, Apostolos Bossios, Hadi Valadi, Ross Vlahos, Carina Malmhall, Margareta Sjostrand, Jay K Kolls, Gary P Anderson, Anders Linden

Journal article  |  2007  |  American Journal of Respiratory Cell and Molecular Biology

Regulation of hypothalamic NPY by diet and smoking

Hui Chen, Michelle J Hansen, Jessica E Jones, Ross Vlahos, Steve Bozinovski, Gary P Anderson, Margaret J Morris

Journal article  |  2007  |  Peptides

Therapeutic potential of treating chronic obstructive pulmonary disease (COPD) by neutralising granulocyte macrophage-colony stimulating factor (GM-CSF)

R Vlahos, S Bozinovski, JA Hamilton, GP Anderson

Journal article  |  2006  |  Pharmacology and Therapeutics

Cigarette smoke exposure reprograms the hypothalamic neuropeptide Y axis to promote weight loss

Hui Chen, Michelle J Hansen, Jessica E Jones, Ross Vlahos, Steve Bozinovski, Gary P Anderson, Margaret J Morris

Journal article  |  2006  |  American Journal of Respiratory and Critical Care Medicine

Differential protease, innate immunity, and NF-kappa B induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice

R Vlahos, S Bozinovski, JE Jones, J Powell, J Gras, A Lilja, MJ Hansen, RC Gualano, L Irving, GP Anderson

Journal article  |  2006  |  American Journal of Physiology - Lung Cellular and Molecular Physiology

Modelling COPD in mice

R Vlahos, S Bozinovski, RC Gualano, M Ernst, GP Anderson

Journal article  |  2006  |  Pulmonary Pharmacology and Therapeutics

Therapeutic prospects to treat skeletal muscle wasting in COPD (chronic obstructive lung disease)

MJ Hansen, RC Gualano, S Bozinovski, R Vlahos, GP Anderson

Journal article  |  2006  |  Pharmacology and Therapeutics

Akt in the pathogenesis of COPD.

Steven Bozinovski, Ross Vlahos, Michelle Hansen, Ken Liu, Gary P Anderson

Journal article  |  2006  |  The International Journal of Chronic Obstructive Pulmonary Disease

In this review we consider the therapeutic potential of targeting Akt for the treatment of COPD. Akt is a serine/threonine protein..

Effect of short-term cigarette smoke exposure on body weight, appetite and brain neuropeptide Y in mice

H Chen, R Vlahos, S Bozinovski, J Jones, GP Anderson, MJ Morris

Journal article  |  2005  |  Neuropsychopharmacology

Unaltered TNF-alpha production by macrophages and monocytes in diet-induced obesity in the rat.

Sammy Bedoui, Elena Velkoska, Steve Bozinovski, Jessica E Jones, Gary P Anderson, Margaret J Morris

Journal article  |  2005  |  Journal of Inflammation

BACKGROUND: Recent findings have established an association between obesity and immune dysfunction. However, most of the studies i..

S100A8 chemotactic protein is abundantly increased, but only a minor contributor to LPS-induced, steroid resistant neutrophilic lung inflammation in vivo

S Bozinovski, M Cross, R Vlahos, JE Jones, K Hsuu, PA Tessier, EC Reynolds, DA Hume, JA Hamilton, CL Geczy, GP Anderson

Journal article  |  2005  |  Journal of Proteome Research

Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells

M Laan, S Bozinovski, GP Anderson

Journal article  |  2004  |  Journal of Immunology

Increased matrix metalloproteinase-9 concentration and activity after stimulation with interleukin-17 in mouse airways

O Prause, S Bozinovski, GP Anderson, A Linden

Journal article  |  2004  |  Thorax

Innate immune responses to LPS in mouse lung are suppressed and reversed by neutralization of GM-CSF via repression of TLR-4

S Bozinovski, J Jones, SJ Beavitt, AD Cook, JA Hamilton, GP Anderson

Journal article  |  2004  |  American Journal of Physiology - Lung Cellular and Molecular Physiology

Imbalanced gp130-dependent signaling in macrophages alters macrophage colony-stimulating factor responsiveness via regulation of c-fms expression

BJ Jenkins, D Grail, M Inglese, C Quilici, S Bozinovski, P Wong, M Ernst

Journal article  |  2004  |  Molecular and Cellular Biology

Acquired somatic mutations in the molecular pathogenesis of COPD

GP Anderson, S Bozinovski

Journal article  |  2003  |  Trends in Pharmacological Sciences

Granulocyte/macrophage-colony-stimulating factor (GM-CSF) regulates lung innate immunity to lipopolysaccharide through Akt/Erk activation of NF kappa B and AP-1 in vivo

S Bozinovski, JE Jones, R Vlahos, JA Hamilton, GP Anderson

Journal article  |  2002  |  Journal of Biological Chemistry

Constitutive activation of the Src family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response

M Ernst, M Inglese, GM Scholz, KW Harder, FJ Clay, S Bozinovski, P Waring, R Darwiche, T Kay, P Sly, R Collins, D Turner, ML Hibbs, GP Anderson, AR Dunn

Journal article  |  2002  |  Journal of Experimental Medicine