Steven Bozinovski

Novel Therapies for Pneumonia-Associated Severe Asthma Phenotypes

Angelica Papanicolaou, Hao Wang, Catherine Satzke, Ross Vlahos, Nick Wilson, Steven Bozinovski

Journal article  |  2020  |  TRENDS IN MOLECULAR MEDICINE

Distinct asthma phenotypes are emerging from well-defined cohort studies and appear to be associated with a history of pneumonia. ..

Influenza A virus causes maternal and fetal pathology via innate and adaptive vascular inflammation in mice.

Stella Liong, Osezua Oseghale, Eunice E To, Kurt Brassington, Jonathan R Erlich, Raymond Luong, Felicia Liong, Robert Brooks, Cara Martin, Sharon O'Toole, Antony Vinh, Luke AJ O'Neill, Steven Bozinovski, Ross Vlahos, Paris C Papagianis, John J O'Leary, Doug A Brooks, Stavros Selemidis

Journal article  |  2020  |  Proc Natl Acad Sci U S A

Influenza A virus (IAV) infection during pregnancy causes severe maternal and perinatal complications, despite a lack of vertical ..

Ambulatory Oxygen in Fibrotic Interstitial Lung Disease A Pilot, Randomized, Triple-Blinded, Sham-Controlled Trial

Yet H Khor, Anne E Holland, Nicole SL Goh, Belinda R Miller, Ross Vlahos, Steven Bozinovski, Aroub Lahham, Ian Glaspole, Christine F McDonald

Journal article  |  2020  |  Chest

Background Despite a lack of evidence, ambulatory oxygen therapy is frequently prescribed for patients with interstitial lung dise..

Increased MUC1 plus a larger quantity and complex size for MUC5AC in the peripheral airway lumen of long-term tobacco smokers.

Médea Padra, Anders Andersson, Bettina Levänen, Pushpa Premaratne, Helga Asgeirsdottir, Sara Tengvall, Karin Christenson, Marit Stockfelt, Steven Bozinovski, Shigemi Yoshihara, Ann-Sofie Lantz, Lena Palmberg, Barbro Dahlén, Kjell Larsson, Ingemar Qvarfordt, Sara K Lindén, Anders Lindén

Journal article  |  2020  |  Clin Sci (Lond)

There is little information on mucins versus potential regulatory factors in the peripheral airway lumen of long-term smokers with..

Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses

Eunice E To, John J O'Leary, Luke AJ O'Neill, Ross Vlahos, Steven Bozinovski, Christopher JH Porter, Robert D Brooks, Doug A Brooks, Stavros Selemidis

Journal article  |  2020  |  ANTIOXIDANTS & REDOX SIGNALING

Significance: Reactive oxygen species (ROS) are often considered to be undesirable toxic molecules that are generated under condit..

Cigarette Smoking Exacerbates Skeletal Muscle Injury without Compromising Its Regenerative Capacity.

Stanley MH Chan, Claudia Cerni, Samantha Passey, Huei Jiunn Seow, Ivan Bernardo, Chris van der Poel, Aleksandar Dobric, Kurt Brassington, Stavros Selemidis, Steven Bozinovski, Ross Vlahos

Journal article  |  2020  |  Am J Respir Cell Mol Biol

Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease negatively impacts quality of life and survival..

Novel multiplex droplet digital PCR assay for scoring PD-L1 in non-small cell lung cancer biopsy specimens

Amanda Vannitamby, Shona Hendry, Louis Irving, Daniel Steinfort, Steven Bozinovski

Journal article  |  2019  |  LUNG CANCER

OBJECTIVES: Immune checkpoint inhibitors have become integrated into the clinical management of non-small cell lung cancer (NSCLC)..

Sensitive molecular testing methods can demonstrate NSCLC driver mutations in malignant pleural effusion despite nonmalignant cytology

Daniel P Steinfort, Sevastjan Kranz, Anthony Dowers, Leakhena Leas, Voula Dimitriadis, Kym Pham, Arthur Hsu, Steven Bozinovski, Louis B Irving, Paula Loveland, Michael Christie

Journal article  |  2019  |  TRANSLATIONAL LUNG CANCER RESEARCH

Malignant pleural effusion (MPE) may be diagnosed by cytologic evaluation of pleural fluid, though false negative results can occu..

Excessive Reactive Oxygen Species Inhibit IL-17A( ) gamma delta T Cells and Innate Cellular Responses to Bacterial Lung Infection

Desiree Anthony, Angelica Papanicolaou, Hao Wang, Huei Jiunn Seow, Eunice E To, Selcuk Yatmaz, Gary P Anderson, Odilia Wijburg, Stavros Selemidis, Ross Vlahos, Steven Bozinovski

Journal article  |  2019  |  ANTIOXIDANTS & REDOX SIGNALING

Aims: Excessive reactive oxygen species (ROS) are detrimental to immune cellular functions that control pathogenic microbes; howev..

In vivo imaging of brain muscarinic receptors with F-18 Flurobenzyl Dexetimide: First in human studies

Christopher Rowe, Brian Dean, Uwe Ackermann, Rachel Goh, Rodney Guzman, Richard Kanaan, Lee Chong, Vincent Dore, Svetlana Bozinovski, Colin Masters, Victor Villemagne

Conference Proceedings  |  2019  |  JOURNAL OF NUCLEAR MEDICINE