Lauren Hyde

Bacterial membrane permeability of antimicrobial polymethacrylates: Evidence for a complex mechanism from super-resolution fluorescence imaging

Thomas D Michl, Ben Hibbs, Lauren Hyde, Almar Postma, Thuy Thi Tran Dung, Aigerim Zhalgasbaikyzy, Krasimir Vasilev, Laurence Meagher, Hans J Griesser, Katherine ES Locock

Journal article  |  2020  |  ACTA BIOMATERIALIA

Amphiphilic polymers bearing cationic moieties are an emerging alternative to traditional antibiotics given their broad-spectrum a..

High Throughput Techniques for the Investigation of Cell-Material Interactions

Lauren R Clements, Helmut Thissen, Nicolas H Voelcker

Journal article  |  2015  |  BIOINTERFACES: WHERE MATERIAL MEETS BIOLOGY

Screening rat mesenchymal stem cell attachment and differentiation on surface chemistries using plasma polymer gradients

Peng-Yuan Wang, Lauren R Clements, Helmut Thissen, Wei-Bor Tsai, Nicolas H Voelcker

Journal article  |  2015  |  ACTA BIOMATERIALIA

It is well known that the surface chemistry of biomaterials is important for both initial cell attachment and the downstream cell ..

High-throughput characterisation of osteogenic differentiation of human mesenchymal stem cells using pore size gradients on porous alumina

Peng-Yuan Wang, Lauren R Clements, Helmut Thissen, Wei-Bor Tsai, Nicolas H Voelcker

Journal article  |  2013  |  BIOMATERIALS SCIENCE

The ability to control the cellular response is of critical importance when designing advanced biomaterials for applications in ti..

Screening Mesenchymal Stem Cell Attachment and Differentiation on Porous Silicon Gradients

Peng-Yuan Wang, Lauren R Clements, Helmut Thissen, Andrew Jane, Wei-Bor Tsai, Nicolas H Voelcker

Journal article  |  2012  |  ADVANCED FUNCTIONAL MATERIALS

The profound effects that nanoscale surface topography exerts on cell behavior are highly relevant to the development of advanced ..

Assessing embryonic stem cell response to surface chemistry using plasma polymer gradients

Frances J Harding, Lauren R Clements, Robert D Short, Helmut Thissen, Nicolas H Voelcker

Journal article  |  2012  |  ACTA BIOMATERIALIA

The control of cell-material interactions is the key to a broad range of biomedical interactions. Gradient surfaces have recently ..

Gradient Technology for High-Throughput Screening of Interactions between Cells and Nanostructured Materials

Andrew Michelmore, Lauren Clements, David A Steele, Nicolas H Voelcker, Endre J Szili

Journal article  |  2012  |  JOURNAL OF NANOMATERIALS

We present a novel substrate suitable for the high-throughput analysis of cell response to variations in surface chemistry and nan..

Electrochemistry-enabled fabrication of orthogonal nanotopography and surface chemistry gradients for high-throughput screening

Lauren R Clements, Peng-Yuan Wang, Wei-Bor Tsai, Helmut Thissen, Nicolas H Voelcker

Journal article  |  2012  |  LAB ON A CHIP

Gradient surfaces are emerging tools for investigating mammalian cell-surface interactions in high throughput. We demonstrate the ..

Screening the attachment and spreading of bone marrow-derived and adipose-derived mesenchymal stem cells on porous silicon gradients

Peng-Yuan Wang, Lauren R Clements, Helmut Thissen, Shih-Chieh Hung, Nai-Chen Cheng, Wei-Bor Tsai, Nicolas H Voelcker

Journal article  |  2012  |  RSC ADVANCES

Nanoscale surface topography exerts profound effects on stem cell behaviour. Detailed knowledge of these effects is of key relevan..

Mesenchymal stem cell attachment to peptide density gradients on porous silicon generated by electrografting

Lauren R Clements, Peng-Yuan Wang, Frances Harding, Wei-Bor Tsai, Helmut Thissen, Nicolas H Voelcker

Journal article  |  2011  |  PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE

Chemical gradients of ethyl-6-bromohexanoate (EBH) were generated over porous silicon (pSi) substrates via electrochemical attachm..