Francine Ke

Combined reduction in the expression of MCL-1 and BCL-2 reduces organismal size in mice

Francine Ke, Graeme Lancaster, Stephanie Grabow, Andrew J Murphy, Andreas Strasser

Journal article  |  2020  |  Cell Death and Disease

BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals

Rahul Srivastava, Zhipeng Cao, Christina Nedeva, Samara Naim, Daniel Bachmann, Tatiana Rabachini, Lahiru Gangoda, Sanjay Shahi, Jason Glab, Joseph Menassa, Laura Osellame, Tao Nelson, Yuniel Fernandez-Marrero, Fiona Brown, Andrew Wei, Francine Ke, Lorraine O'Reilly, Marcel Doerflinger, Cody Allison, Andrew Kueh, et al.

Journal article  |  2019  |  Proceedings of the National Academy of Sciences of USA

BCL-2 family proteins regulate the mitochondrial apoptotic pathway. BOK, a multidomain BCL-2 family protein, is generally believed..

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects

Alex RD Delbridge, Andrew J Kueh, Francine Ke, Natasha M Zamudio, Farrah El-Saafin, Natasha Jansz, Gao-Yuan Wang, Megan Iminitoff, Tamara Beck, Sue Haupt, Yifang Hu, Rose E May, Lachlan Whitehead, Lin Tai, William Chiang, Marco J Herold, Ygal Haupt, Gordon K Smyth, Tim Thomas, Marnie E Blewitt, et al.

Journal article  |  2019  |  Cell Reports

Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities

Stephanie Grabow, Andrew J Kueh, Francine Ke, Hannah K Vanyai, Bilal N Sheikh, Michael A Dengler, William Chiang, Samantha Eccles, Ian M Smyth, Lynelle K Jones, Frederic J de Sauvage, Mark Scott, Lachlan Whitehead, Anne K Voss, Andreas Strasser

Journal article  |  2018  |  Cell Reports

Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK

Francine FS Ke, Hannah K Vanyai, Angus D Cowan, Alex RD Delbridge, Lachlan Whitehead, Stephanie Grabow, Peter E Czabotar, Anne K Voss, Andreas Strasser

Journal article  |  2018  |  Cell

Is BOK required for apoptosis induced by endoplasmic reticulum stress?

Yuniel Fernandez-Marrero, Francine Ke, Nohemy Echeverry, Philippe Bouillet, Daniel Bachmann, Andreas Strasser, Thomas Kaufmann

Journal article  |  2016  |  Proceedings of the National Academy of Sciences of the United States of America

Impact of the combined loss of BOK, BAX and BAK on the hematopoietic system is slightly more severe than compound loss of BAX and BAK

F Ke, S Grabow, GL Kelly, A Lin, LA O'Reilly, A Strasser

Journal article  |  2015  |  Cell Death and Disease

Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

Ramanjaneyulu Allam, Kate E Lawlor, Eric Chi-Wang Yu, Alison L Mildenhall, Donia M Moujalled, Rowena S Lewis, Francine Ke, Kylie D Mason, Michael J White, Katryn J Stacey, Andreas Strasser, Lorraine A O'Reilly, Warren Alexander, Benjamin T Kile, David L Vaux, James E Vince

Journal article  |  2014  |  EMBO Reports

Consequences of the combined loss of BOK and BAK or BOK and BAX

F Ke, P Bouillet, T Kaufmann, A Strasser, J Kerr, AK Voss

Journal article  |  2013  |  Cell Death and Disease

Intracellular localization of the BCL-2 family member BOK and functional implications

N Echeverry, D Bachmann, F Ke, A Strasser, HU Simon, T Kaufmann

Journal article  |  2013  |  Cell Death & Differentiation