Annette Fox Marsh

Within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children

Alvin X Han, Zandra C Felix Garza, Matthijs RA Welkers, Rene M Vigeveno, Duong Tran Nhu, Quynh Mai Le Thi, Pham Quang Thai, Thoang Dang Dinh, Ngoc Anh Tran Thi, Tuan Ha Manh, Hung Nguyen Thanh, Thinh Le Quoc, Hai Le Thanh, Bich Ngoc Hoang Thi, Kulkanya Chokephaibulkit, Pilaipan Puthavathana, Vinh Chau Nguyen Van, Ngoc Nghiem My, Kinh Nguyen Van, Trinh Dao Tuyet, et al.

Journal article  |  2021  |  ELIFE

The evolution of influenza viruses is fundamentally shaped by within-host processes. However, the within-host evolutionary dynamic..

Impact of prior vaccination on antibody response and influenza-like illness among Australian healthcare workers after influenza vaccination in 2016

Vivian KY Leung, Annette Fox, Louise A Carolan, Malet Aban, Karen L Laurie, Julian Druce, Yi-Mo Deng, Monica A Slavin, Caroline Marshall, Sheena G Sullivan

Journal article  |  2021  |  VACCINE

BACKGROUND: Epidemiological studies suggest that influenza vaccine effectiveness decreases with repeated administration. We examin..

Symptoms and laboratory manifestations of mild COVID-19 in a repatriated cruise ship cohort

CR Bailie, L Franklin, S Nicholson, F Mordant, C Alpren, T Stewart, C Barnes, A Fox, J Druce, K Subbarao, M Catton, A van Diemen, SG Sullivan

Journal article  |  2021  |  EPIDEMIOLOGY AND INFECTION

Much of our current understanding about novel coronavirus disease 2019 (COVID-19) comes from hospitalised patients. However, the s..

Influenza A(H1N1)pdm09 but not A(H3N2) virus infection induces durable sero-protection: results from the Ha Nam Cohort.

Le Nguyen Minh Hoa, Sheena G Sullivan, Le Quynh Mai, Arseniy Khvorov, Hoang Vu Mai Phuong, Nguyen Le Khanh Hang, Pham Quang Thai, Le Thi Thanh, Louise Carolan, Dang Duc Anh, Tran Nhu Duong, Juliet E Bryant, H Rogier van Doorn, Heiman FL Wertheim, Peter Horby, Annette Fox

Journal article  |  2020  |  J Infect Dis

BACKGROUND: The extent to which influenza recurrence depends upon waning immunity from prior-infection is undefined. We used antib..

Neuraminidase escape attempts

Annette Fox, Louise Carolan

Journal article  |  2019  |  NATURE MICROBIOLOGY

Recalling the Future: Immunological Memory Toward Unpredictable Influenza Viruses

Maria Auladell, Xiaoxiao Jia, Luca Hensen, Brandon Chua, Annette Fox, Thi HO Nguyen, Peter C Doherty, Katherine Kedzierska

Journal article  |  2019  |  FRONTIERS IN IMMUNOLOGY

Persistent and durable immunological memory forms the basis of any successful vaccination protocol. Generation of pre-existing mem..

Distinguishing naive- from memory-derived human B cells during acute responses

Maria Auladell, Ho Nguyen Thi, Beatriz Garcillan, Fabienne Mackay, Katherine Kedzierska, Annette Fox

Journal article  |  2019  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

Objectives: A fundamental question in influenza research is whether antibody titre decline upon successive exposure to variant str..

Limited Phenotypic and Functional Plasticity of Influenza Virus-Specific Memory CD8( ) T Cells during Activation in an Alternative Cytokine Environment

Kim L Harland, Annette Fox, Simone Nussing, Luca Hensen, Katherine Kedzierska, Stephen J Turner, Anne Kelso

Journal article  |  2018  |  JOURNAL OF IMMUNOLOGY

Naive CD8+ T cells show phenotypic, functional, and epigenetic plasticity, enabling differentiation into distinct cellular states...

Extending the Breadth of Influenza Vaccines: Status and Prospects for a Universal Vaccine

Annette Fox, Kylie M Quinn, Kanta Subbarao

Journal article  |  2018  |  DRUGS

Despite the widespread use of seasonal influenza vaccines, there is urgent need for a universal influenza vaccine to provide broad..

Age-Related Decline in Primary CD8( ) T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8( ) T Cells

Kylie M Quinn, Annette Fox, Kim L Harland, Brendan E Russ, Jasmine Li, Thi HO Nguyen, Liyen Loh, Moshe Olshanksy, Haroon Naeem, Kirill Tsyganov, Florian Wiede, Rosela Webster, Chantelle Blyth, Xavier YX Sng, Tony Tiganis, David Powell, Peter C Doherty, Stephen J Turner, Katherine Kedzierska, Nicole L La Gruta

Journal article  |  2018  |  CELL REPORTS

Age-associated decreases in primary CD8+ T cell responses occur, in part, due to direct effects on naive CD8+ T cells to reduce in..