Mark Waltham

Human-specific RNA analysis shows uncoupled epithelial-mesenchymal plasticity in circulating and disseminated tumour cells from human breast cancer xenografts

Anthony Tachtsidis, Anh Viet-Phuong Le, Tony Blick, Devika Gunasinghe, Emma De Sousa, Mark Waltham, Alex Dobrovic, Erik W Thompson

Journal article  |  2019  |  Clinical & Experimental Metastasis

Interrogation of Phenotypic Plasticity between Epithelial and Mesenchymal States in Breast Cancer

Sugandha Bhatia, James Monkman, Tony Blick, Cletus Pinto, Mark Waltham, Shivashankar H Nagaraj, Erik W Thompson

Journal article  |  2019  |  Journal of Clinical Medicine

Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin

HJ Hugo, NPAD Gunasinghe, BG Hollier, T Tanaka, T Blick, A Toh, P Hill, C Gilles, M Waltham, EW Thompson

Journal article  |  2017  |  Breast Cancer Research

Mammographically dense human breast tissue stimulates MCF10DCIS.com progression to invasive lesions and metastasis

Cecilia W Huo, Mark Waltham, Christine Khoo, Stephen B Fox, Prue Hill, Shou Chen, Grace L Chew, John T Price, Chau H Nguyen, Elizabeth D Williams, Michael Henderson, Erik W Thompson, Kara L Britt

Journal article  |  2016  |  Breast Cancer Research

Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines

J Cursons, KJ Leuchowius, M Waltham, E Tomaskovic-Crook, M Foroutan, CP Bracken, A Redfern, EJ Crampin, I Street, MJ Davis, EW Thompson

Journal article  |  2015  |  Cell Communication and Signaling

Breast cancer stem cells and epithelial mesenchymal plasticity - Implications for chemoresistance

Cletus A Pinto, Edwin Widodo, Mark Waltham, Erik W Thompson

Journal article  |  2013  |  Cancer Letters

Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor

Theodora Fifis, Linh Nguyen, Cathy Malcontenti-Wilson, Lie Sam Chan, Patricia Luiza Nunes Costa, Jurstine Daruwalla, Mehrdad Nikfarjam, Vijayaragavan Muralidharan, Mark Waltham, Erik W Thompson, Christopher Christophi

Journal article  |  2013  |  Cancer Medicine

Structure of the N-terminal domain of human thioredoxin-interacting protein

Galina Polekhina, David Benjamin Ascher, Shie Foong Kok, Simone Beckham, Matthew Wilce, Mark Waltham

Journal article  |  2013  |  Acta Crystallographica Section D Biological Crystallography

An MMP13-Selective Inhibitor Delays Primary Tumor Growth and the Onset of Tumor-Associated Osteolytic Lesions in Experimental Models of Breast Cancer

Manisha Shah, Dexing Huang, Tony Blick, Andrea Connor, Lawrence A Reiter, Joel R Hardink, Conor C Lynch, Mark Waltham, Erik W Thompson

Journal article  |  2012  |  PLoS One

Crystallization and preliminary X-ray analysis of the N-terminal domain of human thioredoxin-interacting protein

Galina Polekhina, David Benjamin Ascher, Shie Foong Kok, Mark Waltham

Journal article  |  2011  |  Acta Crystallographica Section F Structural Biology and Crystallization Communications

Epithelial-to-Mesenchymal Transitions and Circulating Tumor Cells

Arnaud Bonnomet, Anne Brysse, Anthony Tachsidis, Mark Waltham, Erik W Thompson, Myriam Polette, Christine Gilles

Journal article  |  2010  |  Journal of Mammary Gland Biology and Neoplasia

Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44(hi/)CD24(lo/-) Stem Cell Phenotype in Human Breast Cancer

Tony Blick, Honor Hugo, Edwin Widodo, Mark Waltham, Cletus Pinto, Sendurai A Mani, Robert A Weinberg, Richard M Neve, Marc E Lenburg, Erik W Thompson

Journal article  |  2010  |  Journal of Mammary Gland Biology and Neoplasia

Epithelial mesenchymal transition traits in human breast cancer cell lines

T Blick, E Widodo, H Hugo, M Waltham, ME Lenburg, RM Neve, EW Thompson

Journal article  |  2008  |  Clinical and Experimental Metastasis

Advanced glycation end products decrease mesangial cell MMP-7: A role in matrix accumulation in diabetic nephropathy?

SV McLennan, DJ Kelly, M Schache, M Waltham, V Dy, RG Langham, DK Yue, RE Gilbert

Journal article  |  2007  |  Kidney International

Vimentin and epithelial-mesenchymal transition in human breast cancer - Observations in vitro and in vivo

Maria I Kokkinos, Razan Wafai, Meng Kang Wong, Donald F Newgreen, Erik W Thompson, Mark Waltham

Journal article  |  2007  |  Cells Tissues Organs

Anti sense-mediated suppression of hyaluronan synthase 2 inhibits the tumorigenesis and progression of breast cancer

L Udabage, GR Brownlee, M Waltham, T Blick, EC Walker, P Heldin, SK Nilsson, EW Thompson, TJ Brown

Journal article  |  2005  |  Cancer Research

The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line

JT Price, JMW Quinn, NA Sims, J Vieusseux, K Waldeck, SE Docherty, D Myers, A Nakamura, MC Waltham, MT Gillespie, EW Thompson

Journal article  |  2005  |  Cancer Research

Upregulation of matrix metalloproteinases (MMPs) in breast cancer xenografts: A major induction of stromal MMP-13

MA Lafleur, AF Drew, EL de Sousa, T Blick, M Bills, EC Walker, ED Williams, M Waltham, EW Thompson

Journal article  |  2005  |  International Journal of Cancer

Common origins of MDA-MB-435 cells from various sources with those shown to have melonoma properties

JM Rae, SJ Ramus, M Waltham, JE Armes, IG Campbell, R Clarke, RJ Barndt, MD Johnson, EW Thompson

Journal article  |  2004  |  Clinical and Experimental Metastasis

Transfection of MDA-MB-231 human breast carcinoma cells with bone sialoprotein (BSP) stimulates migration and invasion in vitro and growth of primary and secondary tumors in nude mice

JA Sharp, M Waltham, ED Williams, MA Henderson, EW Thompson

Journal article  |  2004  |  Clinical and Experimental Metastasis

LCC15-MB cells are MDA-MB-435: A review of misidentified breast and prostate cell lines

EW Thompson, M Waltham, SJ Ramus, AM Hutchins, JE Armes, IG Campbell, ED Williams, PR Thompson, JM Rae, MD Johnson, R Clarke

Journal article  |  2004  |  Clinical and Experimental Metastasis

Epidermal growth factor-induced epithelio-mesenchymal transition in human breast carcinoma cells

ML Ackland, DF Newgreen, M Fridman, MC Waltham, A Arvanitis, J Minichiello, JT Price, EW Thompson

Journal article  |  2003  |  Laboratory Investigation

Correlation between extent of osteolytic damage and metastatic burden of human breast cancer metastasis in nude mice: Real-time PCR quantitation

AM Tester, JA Sharp, N Dhanesuan, M Waltham, EW Thompson

Journal article  |  2002  |  Clinical and Experimental Metastasis