Daniel Buchanan

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis.

Nikos Papadimitriou, Niki Dimou, Konstantinos K Tsilidis, Barbara Banbury, Richard M Martin, Sarah J Lewis, Nabila Kazmi, Timothy M Robinson, Demetrius Albanes, Krasimira Aleksandrova, Sonja I Berndt, D Timothy Bishop, Hermann Brenner, Daniel D Buchanan, Bas Bueno-de-Mesquita, Peter T Campbell, Sergi Castellví-Bel, Andrew T Chan, Jenny Chang-Claude, Merete Ellingjord-Dale, et al.

Journal article  |  2020  |  Nature Communications

Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it is ..

Overall lack of replication of associations between dietary intake of folate and vitamin B-12 and DNA methylation in peripheral blood

Pierre-Antoine Dugue, James A Chamberlain, Julie K Bassett, Allison M Hodge, Maree T Brinkman, JiHoon E Joo, Chol-Hee Jung, Ee Ming Wong, Enes Makalic, Daniel F Schmidt, John L Hopper, Daniel D Buchanan, Dallas R English, Roger L Milne, Melissa C Southey, Graham G Giles

Journal article  |  2020  |  The American Journal of Clinical Nutrition

Evaluating the utility of tumour mutational signatures for identifying hereditary colorectal cancer and polyposis syndrome carriers

Peter Georgeson, Bernard Pope, Christophe Rosty, Mark Clendenning, Romy Walker, Khalid Mahmood, Jihoon Joo, Ryan Hutchinson, Susan Preston, Julia Como, Sharelle Joseland, Aung Ko Win, Finlay Macrae, John Hopper, Mark Jenkins, Ingrid Winship, Daniel Buchanan

Journal article  |  2019

Objective: Germline pathogenic variants (PVs) in the DNA mismatch repair (MMR) genes and the base excision repair genes NTHL1 and ..

Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Zahra Montazeri, Xue Li, Christine Nyiraneza, Xiangyu Ma, Maria Timofeeva, Victoria Svinti, Xiangrui Meng, Yazhou He, Yacong Bo, Samuel Morgan, Sergi Castellví-Bel, Clara Ruiz-Ponte, Ceres Fernández-Rozadilla, Ángel Carracedo, Antoni Castells, Timothy Bishop, Daniel Buchanan, Mark A Jenkins, Temitope O Keku, Annika Lindblom, et al.

Journal article  |  2019  |  Gut

OBJECTIVE: To provide an understanding of the role of common genetic variations in colorectal cancer (CRC) risk, we report an upda..

Type 2 diabetes mellitus, blood cholesterol, triglyceride and colorectal cancer risk in Lynch syndrome

S Ghazaleh Dashti, Wing Yan Li, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Sheetal Hardikar, Xinwei Hua, Stephen N Thibodeau, Jane C Figueiredo, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Noralane M Lindor, John L Hopper, et al.

Journal article  |  2019  |  British Journal of Cancer

BACKGROUND: Type 2 diabetes mellitus and high total cholesterol and triglycerides are known to be associated with increased colore..

Ability of known susceptibility SNPs to predict colorectal cancer risk for persons with and without a family history.

Mark A Jenkins, Aung K Win, James G Dowty, Robert J MacInnis, Enes Makalic, Daniel F Schmidt, Gillian S Dite, Mirosl Kapuscinski, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Jon D Emery, Sibel Saya, Finlay A Macrae, Dennis J Ahnen, David Duggan, Jane C Figueiredo, Noralane M Lindor, Robert W Haile, John D Potter, et al.

Journal article  |  2019  |  Familial Cancer

Before SNP-based risk can be incorporated in colorectal cancer (CRC) screening, the ability of these SNPs to estimate CRC risk for..

Hi-Plex2: a simple and robust approach to targeted sequencing-based genetic screening

Fleur Hammet, Khalid Mahmood, Thomas R Green, Nguyen-Dumont Tu, Melissa C Southey, Daniel D Buchanan, Andrew Lonie, Katherine L Nathanson, Fergus J Couch, Bernard J Pope, Daniel J Park

Journal article  |  2019  |  BioTechniques

We have previously reported Hi-Plex, a multiplex PCR methodology for building targeted DNA sequencing libraries that offers a low-..

Risks of Colorectal Cancer and Cancer-Related Mortality in Familial Colorectal Cancer Type X and Lynch Syndrome Families

Yun-Hee Choi, Lajmi Lakhal-Chaieb, Agnieszka Krol, Bing Yu, Daniel Buchanan, Dennis Ahnen, Loic Le Marchand, Polly A Newcomb, Aung Ko Win, Mark Jenkins, Noralane M Lindor, Laurent Briollais

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Background: The risk of cancers is well characterized in Lynch syndrome (LS) families but has been less studied in familial colore..

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer (vol 138, pg 307, 2019)

Stephanie A Bien, Yu-Ru Su, David V Conti, Tabitha A Harrison, Conghui Qu, Xingyi Guo, Yingchang Lu, Demetrius Albanes, Paul L Auer, Barbara L Banbury, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Andrew T Chan, Jenny Chang-Claude, Sai Chen, et al.

Journal article  |  2019  |  Human Genetics

Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome

Peter Georgeson, Michael D Walsh, Mark Clendenning, Simin Daneshvar, Bernard J Pope, Khalid Mahmood, Jihoon E Joo, Harindra Jayasekara, Mark A Jenkins, Ingrid M Winship, Daniel D Buchanan

Journal article  |  2019  |  Molecular Genetics & Genomic Medicine

Phenotypic confirmation of oligodontia, colorectal polyposis and cancer in a family carrying an exon 7 nonsense variant in the AXIN2 gene

Catherine Beard, Rebecca Purvis, Ingrid M Winship, Finlay A Macrae, Daniel D Buchanan

Journal article  |  2019  |  Familial Cancer

Mendelian randomization analysis of C-reactive protein on colorectal cancer risk

Xiaoliang Wang, James Y Dai, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Katja Butterbach, Bette Caan, Graham Casey, Peter T Campbell, Andrew T Chan, Zhengyi Chen, Jenny Chang-Claude, Michelle Cotterchio, Douglas F Easton, Graham G Giles, Edward Giovannucci, William M Grady, et al.

Journal article  |  2019  |  International Journal of Epidemiology

Background: Chronic inflammation is a risk factor for colorectal cancer (CRC). Circulating C-reactive protein (CRP) is also modera..

Association analyses identify 31 new risk loci for colorectal cancer susceptibility

Philip J Law, Maria Timofeeva, Ceres Fernandez-Rozadilla, Aria Timofeeva, Peter Broderick, James Studd, Juan Fernandez-Tajes, Susan Farrington, Victoria Svinti, Claire Palles, Giulia Orlando, Amit Sud, Amy Holroyd, Steven Penegar, Evropi Theodoratou, Peter Vaughan-Shaw, Harry Campbell, Lina Zgaga, Caroline Hayward, Archie Campbell, et al.

Journal article  |  2019  |  Nature Communications

Clinico-pathological predictors of mismatch repair deficiency in sebaceous neoplasia: A large case series from a single Australian private pathology service

Michael D Walsh, Harindra Jayasekara, Alvin Huang, Ingrid M Winship, Daniel D Buchanan

Journal article  |  2019  |  Australasian Journal of Dermatology

Circulating 25-Hydroxyvitamin D Concentration and Risk of Breast, Prostate, and Colorectal Cancers: The Melbourne Collaborative Cohort Study

Alicia K Heath, Allison M Hodge, Peter R Ebeling, Darryl W Eyles, David Kvaskoff, Daniel D Buchanan, Graham G Giles, Elizabeth J Williamson, Dallas R English

Journal article  |  2019  |  Cancer Epidemiology Biomarkers & Prevention

BACKGROUND: The role of vitamin D in cancer risk remains controversial, and limited data exist on associations between vitamin D a..

Assessing the ProMCol classifier as a prognostic marker for non-metastatic colorectal cancer within the Melbourne Collaborative Cohort Study

Jihoon E Joo, Harindra Jayasekara, Ee Ming Wong, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Mark A Jenkins, John L Hopper, Dallas R English, Roger L Milne, Graham G Giles, Melissa C Southey, Daniel D Buchanan

Journal article  |  2019  |  Gut

Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer

Stephanie A Bien, Yu-Ru Su, David V Conti, Tabitha A Harrison, Conghui Qu, Xingyi Guo, Yingchang Lu, Demetrius Albanes, Paul L Auer, Barbara L Banbury, Sonja I Berndt, Stephane Bezieau, Hermann Brenner, Daniel D Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Andrew T Chan, Jenny Chang-Claude, Sai Chen, et al.

Journal article  |  2019  |  Human Genetics

Cancer Risks for PMS2-Associated Lynch Syndrome (vol 29, pg 2961, 2018)

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, Liselotte van Hest, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, et al.

Journal article  |  2019  |  Journal of Clinical Oncology

Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype

Judith E Grolleman, Richarda M de Voer, Fadwa A Elsayed, Maartje Nielsen, Robbert DA Weren, Claire Palles, Marjolijn JL Ligtenberg, Janet R Vos, Sanne W ten Broeke, Noel FCC de Miranda, Renske A Kuiper, Eveline J Kamping, Erik AM Jansen, M Elisa Vink-Borger, Isabell Popp, Alois Lang, Isabel Spier, Robert Hueneburg, Paul A James, Na Li, et al.

Journal article  |  2019  |  Cancer Cell

Novel Common Genetic Susceptibility Loci for Colorectal Cancer

Stephanie L Schmit, Christopher K Edlund, Fredrick R Schumacher, Jian Gong, Tabitha A Harrison, Jeroen R Huyghe, Chenxu Qu, Marilena Melas, David J Van den Berg, Hansong Wang, Stephanie Tring, Sarah J Plummer, Demetrius Albanes, M Henar Alonso, Christopher I Amos, Kristen Anton, Aaron K Aragaki, Volker Arndt, Elizabeth L Barry, Sonja I Berndt, et al.

Journal article  |  2019  |  JNCI: Journal of the National Cancer Institute

Shared heritability and functional enrichment across six solid cancers

Xia Jiang, Hilary K Finucane, Fredrick R Schumacher, Stephanie L Schmit, Jonathan P Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline B Kuchenbaecker, Joe Dennis, David V Conti, Graham Casey, Mia M Gaudet, Jeroen R Huyghe, Demetrius Albanes, Melinda C Aldrich, Angeline S Andrew, Irene L Andrulis, Hoda Anton-Culver, Antonis C Antoniou, et al.

Journal article  |  2019  |  Nature Communications

Discovery of common and rare genetic risk variants for colorectal cancer

Jeroen R Huyghe, Stephanie A Bien, Tabitha A Harrison, Hyun Min Kang, Sai Chen, Stephanie L Schmit, David V Conti, Conghui Qu, Jihyoun Jeon, Christopher K Edlund, Peyton Greenside, Michael Wainberg, Fredrick R Schumacher, Joshua D Smith, David M Levine, Sarah C Nelson, Nasa A Sinnott-Armstrong, Demetrius Albanes, M Henar Alonso, Kristin Anderson, et al.

Journal article  |  2019  |  Nature Genetics

Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers

Lyon Mascarenhas, Susan Shanley, Gillian Mitchell, Amanda B Spurdle, Finlay Macrae, Nicholas Pachter, Daniel D Buchanan, Robyn L Ward, Stephen Fox, Elaine Duxbury, Rebecca Driessen, Alex Boussioutas

Journal article  |  2018  |  Asia-Pacific Journal of Clinical Oncology

Risk and prognostic factors for endometrial carcinoma after diagnosis of breast or Lynch-associated cancers-A population-based analysis

Sharon E Johnatty, Colin JR Stewart, Deborah Smith, Daniel Buchanan, Yee Leung, Martin K Oehler, Alison Brand, Penelope M Webb, Amanda B Spurdle

Journal article  |  2018  |  Cancer Medicine

Utility of immunohistochemistry for mismatch repair proteins on colorectal polyps in the familial cancer clinic

Eryn Dow, Daniel D Buchanan, Ingrid M Winship

Journal article  |  2018  |  Internal Medicine Journal

The prognostic impact of consensus molecular subtypes (CMS) and its predictive effects for bevacizumab benefit in metastatic colorectal cancer: molecular analysis of the AGITG MAX clinical trial

JK Mooi, P Wirapati, R Asher, CK Lee, P Savas, TJ Price, A Townsend, J Hardingham, D Buchanan, D Williams, S Tejpar, JM Mariadason, NC Tebbutt

Journal article  |  2018  |  Annals of Oncology

Physical activity and the risk of colorectal cancer in Lynch syndrome

S Ghazaleh Dashti, Aung Ko Win, Sheetal S Hardikar, Stephen E Glombicki, Sheila Mallenahalli, Selvi Thirumurthi, Susan K Peterson, Y Nancy You, Daniel D Buchanan, Jane C Figueiredo, Peter T Campbell, Steven Gallinger, Polly A Newcomb, John D Potter, Noralane M Lindor, Loic Le Marchand, Robert W Haile, John L Hopper, Mark A Jenkins, Karen M Basen-Engquist, et al.

Journal article  |  2018  |  International Journal of Cancer

Cancer Risks for PMS2-Associated Lynch Syndrome

Sanne W ten Broeke, Heleen M van der Klift, Carli MJ Tops, Stefan Aretz, Inge Bernstein, Daniel D Buchanan, Albert de la Chapelle, Gabriel Capella, Mark Clendenning, Christoph Engel, Steven Gallinger, Encarna Gomez Garcia, Jane C Figueiredo, Robert Haile, Heather L Hampel, John L Hopper, Nicoline Hoogerbrugge, Magnus von Knebel Doeberitz, Loic Le Marchand, Tom GW Letteboer, et al.

Journal article  |  2018  |  Journal of Clinical Oncology

Costs and outcomes of Lynch syndrome screening in the Australian colorectal cancer population

Dayna R Cenin, Steffie K Naber, Iris Lansdorp-Vogelaar, Mark A Jenkins, Daniel D Buchanan, David B Preen, Hooi C Ee, Peter O'Leary

Journal article  |  2018  |  Journal of Gastroenterology and Hepatology

DNA mismatch repair protein deficient non-neoplastic colonic crypts: a novel indicator of Lynch syndrome

Rish K Pai, Beth Dudley, Eve Karloski, Randall E Brand, Neil O'Callaghan, Christophe Rosty, Daniel D Buchanan, Mark A Jenkins, Stephen N Thibodeau, Amy J French, Noralane M Lindor, Reetesh K Pai

Journal article  |  2018  |  Modern Pathology

Dietary intake of one-carbon metabolism nutrients and DNA methylation in peripheral blood

James A Chamberlain, Pierre-Antoine Dugue, Julie K Bassett, Allison M Hodge, Maree T Brinkman, JiHoon E Joo, Chol-Hee Jung, Enes Makalic, Daniel F Schmidt, John L Hopper, Daniel D Buchanan, Dallas R English, Melissa C Southey, Graham G Giles, Roger L Milne

Journal article  |  2018  |  The American Journal of Clinical Nutrition

Identification of nine new susceptibility loci for endometrial cancer

Tracy A O'Mara, Dylan M Glubb, Frederic Amant, Daniela Annibali, Katie Ashton, John Attia, Paul L Auer, Matthias W Beckmann, Amanda Black, Manjeet K Bolla, Hiltrud Brauch, Hermann Brenner, Louise Brinton, Daniel D Buchanan, Barbara Burwinkel, Jenny Chang-Claude, Stephen J Chanock, Chu Chen, Maxine M Chen, Timothy HT Cheng, et al.

Journal article  |  2018  |  Nature Communications

Family history-based colorectal cancer screening in Australia: A modelling study of the costs, benefits, and harms of different participation scenarios

Mary Dillon, Louisa Flander, Daniel D Buchanan, Finlay A Macrae, Jon D Emery, Ingrid M Winship, Alex Boussioutas, Graham G Giles, John L Hopper, Mark A Jenkins, Driss Ait Ouakrim

Journal article  |  2018  |  PLOS Medicine

Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1

Daniel D Buchanan, Jenna R Stewart, Mark Clendenning, Christophe Rosty, Khalid Mahmood, Bernard J Pope, Mark A Jenkins, John L Hopper, Melissa C Southey, Finlay A Macrae, Ingrid M Winship, Aung Ko Win

Journal article  |  2018  |  Genet Med

Update on Hereditary Colorectal Cancer: Improving the Clinical Utility of Multigene Panel Testing

Marie Lorans, Eryn Dow, Finlay A Macrae, Ingrid M Winship, Daniel D Buchanan

Journal article  |  2018  |  Clinical Colorectal Cancer

Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors

Jihyoun Jeon, Mengmeng Du, Robert E Schoen, Michael Hoffmeister, Polly A Newcomb, Sonja I Berndt, Bette Caan, Peter T Campbell, Andrew T Chan, Jenny Chang-Claude, Graham G Giles, Jian Gong, Tabitha A Harrison, Jeroen R Huyghe, Eric J Jacobs, Li Li, Yi Lin, Loic Le Marchand, John D Potter, Conghui Qu, et al.

Journal article  |  2018  |  Gastroenterology

Mendelian randomisation study of age at menarche and age at menopause and the risk of colorectal cancer

Sonja Neumeyer, Barbara L Banbury, Volker Arndt, Sonja I Berndt, Stephane Bezieau, Stephanie A Bien, Dan D Buchanan, Katja Butterbach, Bette J Caan, Peter T Campbell, Graham Casey, Andrew T Chan, Stephen J Chanock, James Y Dai, Steven Gallinger, Edward L Giovannucci, Graham G Giles, William M Grady, Jochen Hampe, Michael Hoffmeister, et al.

Journal article  |  2018  |  British Journal of Cancer

Endometrial cancer risk and survival by tumor MMR status

Christina M Nagle, Tracy A O'Mara, Yen Tan, Daniel D Buchanan, Andreas Obermair, Penny Blomfield, Michael A Quinn, Penelope M Webb, Amanda B Spurdle

Journal article  |  2018  |  Journal of Gynecologic Oncology

DNA methylation-based biological aging and cancer risk and survival: Pooled analysis of seven prospective studies

Pierre-Antoine Dugue, Julie K Bassett, JiHoon E Joo, Chol-Hee Jung, Ee Ming Wong, Margarita Moreno-Betancur, Daniel Schmidt, Enes Makalic, Shuai Li, Gianluca Severi, Allison M Hodge, Daniel D Buchanan, Dallas R English, John L Hopper, Melissa C Southey, Graham G Giles, Roger L Milne

Journal article  |  2018  |  International Journal of Cancer

Cohort Profile: The Colon Cancer Family Registry Cohort (CCFRC)

Mark A Jenkins, Aung Ko Win, Allyson S Templeton, Maggie S Angelakos, Daniel D Buchanan, Michelle Cotterchio, Jane C Figueiredo, Stephen N Thibodeau, John A Baron, John D Potter, John L Hopper, Graham Casey, Steven Gallinger, Loic Le Marchand, Noralane M Lindor, Polly A Newcomb, Robert W Haile

Journal article  |  2018  |  International Journal of Epidemiology

Novel associations between blood DNA methylation and body mass index in middle-aged and older adults

YM Geurts, P-A Dugue, JE Joo, E Makalic, C-H Jung, W Guan, S Nguyen, ML Grove, EM Wong, AM Hodge, JK Bassett, LM FitzGerald, H Tsimiklis, L Baglietto, G Severi, DF Schmidt, DD Buchanan, RJ MacInnis, JL Hopper, JS Pankow, et al.

Journal article  |  2018  |  International Journal of Obesity

MMR-deficient Normal Crypts in Patients with Lynch Syndrome

Rish Pai, Amy French, Neil O'Callaghan, Christophe Rosty, Steven Thibodeau, Daniel D Buchanan, Noralane M Lindor, Reetesh Pai

Conference Proceedings  |  2018  |  LABORATORY INVESTIGATION

MMR-deficient Normal Crypts in Patients with Lynch Syndrome

Rish Pai, Amy French, Neil O'Callaghan, Christophe Rosty, Steven Thibodeau, Daniel D Buchanan, Noralane M Lindor, Reetesh Pai

Conference Proceedings  |  2018  |  MODERN PATHOLOGY

Association of DNA Methylation-Based Biological Age With Health Risk Factors and Overall and Cause-Specific Mortality

Pierre-Antoine Dugue, Julie K Bassett, JiHoon E Joo, Laura Baglietto, Chol-Hee Jung, Ee Ming Wong, Giovanni Fiorito, Daniel Schmidt, Enes Makalic, Shuai Li, Margarita Moreno-Betancur, Daniel D Buchanan, Paolo Vineis, Dallas R English, John L Hopper, Gianluca Severi, Melissa C Southey, Graham G Giles, Roger L Milne

Journal article  |  2018  |  American Journal of Epidemiology

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci

Tomas Tanskanen, Linda van den Berg, Niko Valimaki, Mervi Aavikko, Eivind Ness-Jensen, Kristian Hveem, Yvonne Wettergren, Elinor Bexe Lindskog, Neeme Tonisson, Andres Metspalu, Kaisa Silander, Giulia Orlando, Philip J Law, Sari Tuupanen, Alexandra E Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Johanna Kondelin, Antti-Pekka Sarin, Eero Pukkala, et al.

Journal article  |  2018  |  International Journal of Cancer

DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis

Lars Togel, Rebecca Nightingale, Rui Wu, Anderly C Chueh, Sheren Al-Obaidi, Ian Luk, Mercedes Davalos-Salas, Fiona Chionh, Carmel Murone, Daniel D Buchanan, Zac Chatterton, Oliver M Sieber, Diego Arango, Niall C Tebbutt, David Williams, Amardeep S Dhillon, John M Mariadason

Journal article  |  2018  |  Scientific Reports

Genomic Characterization of Upper-Tract Urothelial Carcinoma in Patients With Lynch Syndrome

Timothy E Donahue, Aditya Bagrodia, Francois Audenet, Mark TA Donoghue, Eugene K Cha, John P Sfakianos, Dahlia Sperling, Hikmat Al-Ahmadie, Mark Clendenning, Christophe Rosty, Daniel D Buchanan, Mark Jenkins, John Hopper, Ingrid Winship, Allyson S Templeton, Michael F Walsh, Zsofia K Stadler, Gopa Iyer, Barry Taylor, Jonathan Coleman, et al.

Journal article  |  2018  |  JCO Precision Oncology

Associations of alcohol intake, smoking, physical activity and obesity with survival following colorectal cancer diagnosis by stage, anatomic site and tumor molecular subtype

Harindra Jayasekara, Dallas R English, Andrew Haydon, Allison M Hodge, Brigid M Lynch, Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Melissa C Southey, Mark A Jenkins, Robin Room, John L Hopper, Roger L Milne, Daniel D Buchanan, Graham G Giles, Robert J MacInnis

Journal article  |  2018  |  International Journal of Cancer

Somatic mutations of the coding microsatellites within the beta-2-microglobulin gene in mismatch repair-deficient colorectal cancers and adenomas

Mark Clendenning, Alvin Huang, Harindra Jayasekara, Marie Lorans, Susan Preston, Neil O'Callaghan, Bernard J Pope, Finlay A Macrae, Ingrid M Winship, Roger L Milne, Graham G Giles, Dallas R English, John L Hopper, Aung K Win, Mark A Jenkins, Melissa C Southey, Christophe Rosty, Daniel D Buchanan

Journal article  |  2018  |  Familial Cancer

RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers

Lochlan J Fennell, Mark Clendenning, Diane M McKeone, Saara H Jamieson, Samanthy Balachandran, Jennifer Borowsky, John Liu, Futoshi Kawamata, Catherine E Bond, Christophe Rosty, Matthew E Burge, Daniel D Buchanan, Barbara A Leggett, Vicki LJ Whitehall

Journal article  |  2018  |  Familial Cancer

Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort

Leon Raskin, Yan Guo, Liping Du, Mark Clendenning, Christophe Rosty, Noralane M Lindor, Stephen B Gruber, Daniel D Buchanan

Journal article  |  2017  |  Oncotarget

Family history of cancer predicts endometrial cancer risk independently of Lynch Syndrome: Implications for genetic counselling

Sharon E Johnatty, Yen Y Tan, Daniel D Buchanan, Michael Bowman, Rhiannon J Walters, Andreas Obermair, Michael A Quinn, Penelope B Blomfield, Alison Brand, Yee Leung, Martin K Oehler, Judy A Kirk, Tracy A O'Mara, Penelope M Webb, Amanda B Spurdle

Journal article  |  2017  |  Gynecologic Oncology

Pro-inflammatory fatty acid profile and colorectal cancer risk: A Mendelian randomisation analysis

Sebastian May-Wilson, Amit Sud, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2017  |  European Journal of Cancer

Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes

Melissa S DeRycke, Shanaka Gunawardena, Jessica R Balcom, Angela M Pickart, Lindsey A Waltman, Amy J French, Shannon McDonnell, Shaun M Riska, Zachary C Fogarty, Melissa C Larson, Sumit Middha, Bruce W Eckloff, Yan W Asmann, Matthew J Ferber, Robert W Haile, Steven Gallinger, Mark Clendenning, Christophe Rosty, Aung K Win, Daniel D Buchanan, et al.

Journal article  |  2017  |  Molecular Genetics & Genomic Medicine

Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer

Henry Rodriguez-Broadbent, Philip J Law, Amit Sud, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Samuli Ripatti, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Aarno Palotie, et al.

Journal article  |  2017  |  International Journal of Cancer

Lack of evidence for germline RNF43 mutations in patients with serrated polyposis syndrome from a large multinational study

Daniel D Buchanan, Mark Clendenning, Li Zhuoer, Jenna R Stewart, Sharelle Joseland, Sonja Woodall, Julie Arnold, Kara Semotiuk, Melyssa Aronson, Spring Holter, Steven Gallinger, Mark A Jenkins, Kevin Sweet, Finlay A Macrae, Ingrid M Winship, Susan Parry, Christophe Rosty

Journal article  |  2017  |  Gut

Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study.

R Dienstmann, MJ Mason, FA Sinicrope, AI Phipps, S Tejpar, A Nesbakken, SA Danielsen, A Sveen, DD Buchanan, M Clendenning, C Rosty, B Bot, SR Alberts, J Milburn Jessup, RA Lothe, M Delorenzi, PA Newcomb, D Sargent, J Guinney

Journal article  |  2017  |  Annals of oncology : official journal of the European Society for Medical Oncology

Background: TNM staging alone does not accurately predict outcome in colon cancer (CC) patients who may be eligible for adjuvant c..

Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study

R Dienstmann, MJ Mason, FA Sinicrope, AI Phipps, S Tejpar, A Nesbakken, SA Danielsen, A Sveen, DD Buchanan, M Clendenning, C Rosty, B Bot, SR Alberts, J Milburn Jessup, RA Lothe, M Delorenzi, PA Newcomb, D Sargent, J Guinney

Journal article  |  2017  |  Annals of Oncology

Lifetime alcohol intake is associated with an increased risk of KRAS plus and BRAF-/KRAS- but not BRAF plus colorectal cancer

Harindra Jayasekara, Robert J MacInnis, Elizabeth J Williamson, Allison M Hodge, Mark Clendenning, Christophe Rosty, Rhiannon Walters, Robin Room, Melissa C Southey, Mark A Jenkins, Roger L Milne, John L Hopper, Graham G Giles, Daniel D Buchanan, Dallas R English

Journal article  |  2017  |  International Journal of Cancer

Reducing the polyp burden in serrated polyposis by serial colonoscopy: the impact of nationally coordinated community surveillance

Susan Parry, Randall W Burt, Aung Ko Win, Ye Kyaw Aung, Sonja Woodall, Julie Arnold, Mark Clendenning, Daniel D Buchanan, Timothy J Price, Christophe Rosty, Joanne P Young

Journal article  |  2017  |  The New Zealand medical journal

Germline miRNA DNA Variants and the Risk of Colorectal Cancer by Subtype

Noralane M Lindor, Melissa C Larson, Melissa S DeRycke, Shannon K McDonnell, Saurabh Baheti, Zachary C Fogarty, Aung Ko Win, John D Potter, Daniel D Buchanan, Mark Clendenning, Polly A Newcomb, Graham Casey, Steven Gallinger, Loic Le Marchand, John L Hopper, Mark A Jenkins, Ellen L Goode, Stephen N Thibodeau

Journal article  |  2017  |  Genes, Chromosomes and Cancer

Modeling of Successive Cancer Risks in Lynch Syndrome Families in the Presence of Competing Risks Using Copulas

Yun-Hee Choi, Laurent Briollais, Aung K Win, John Hopper, Dan Buchanan, Mark Jenkins, Lajmi Lakhal-Chaieb

Journal article  |  2017  |  Biometrics

Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer

Aung Ko Win, Mark A Jenkins, James G Dowty, Antonis C Antoniou, Andrew Lee, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Dennis J Ahnen, Stephen N Thibodeau, Graham Casey, Steven Gallinger, Loic Le Marchand, Robert W Haile, John D Potter, Yingye Zheng, Noralane M Lindor, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Alcohol Consumption and the Risk of Colorectal Cancer for Mismatch Repair Gene Mutation Carriers

S Ghazaleh Dashti, Daniel D Buchanan, Harindra Jayasekara, Driss Ait Ouakrim, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Finlay A Macrae, Graham G Giles, Susan Parry, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, et al.

Journal article  |  2017  |  Cancer Epidemiology Biomarkers and Prevention

Tumor testing to identify lynch syndrome in two Australian colorectal cancer cohorts

Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Stine V Eriksen, Michael D Walsh, Rhiannon J Walters, Stephen N Thibodeau, Jenna Stewart, Susan Preston, Aung Ko Win, Louisa Flander, Driss Ait Ouakrim, Finlay A Macrae, Alex Boussioutas, Ingrid M Winship, Graham G Giles, John L Hopper, Melissa C Southey, Dallas English, Mark A Jenkins

Journal article  |  2017  |  Journal of Gastroenterology and Hepatology

Risk factors for metachronous colorectal cancer or polyp: A systematic review and meta-analysis

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Dennis J Ahnen, Susan Parry, Mark A Jenkins, Aung Ko Win

Journal article  |  2017  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

SNP rs16906252C > T Is an Expression and Methylation Quantitative Trait Locus Associated with an Increased Risk of Developing MGMT-Methylated Colorectal Cancer

Joice Kuroiwa-Trzmielina, Fan Wang, Robert W Rapkins, Robyn L Ward, Daniel D Buchanan, Aung Ko Win, Mark Clendenning, Christophe Rosty, Melissa C Southey, Ingrid M Winship, John L Hopper, Mark A Jenkins, Jake Olivier, Nicholas J Hawkins, Megan P Hitchins

Journal article  |  2016  |  Clinical Cancer Research

Methylation of Breast Cancer Predisposition Genes in Early-Onset Breast Cancer: Australian Breast Cancer Family Registry

Cameron M Scott, JiHoon Eric Joo, Neil O'Callaghan, Daniel D Buchanan, Mark Clendenning, Graham G Giles, John L Hopper, Ee Ming Wong, Melissa C Southey

Journal article  |  2016  |  PLOS ONE

Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH

Aung Ko Win, Jeanette C Reece, James G Dowty, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Melissa C Southey, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, Finlay A Macrae, Katherine M Tucker, John A Baron, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

Gordon Fehringer, Peter Kraft, Paul D Pharoah, Rosalind A Eeles, Nilanjan Chatterjee, Fredrick R Schumacher, Joellen M Schildkraut, Sara Lindstrom, Paul Brennan, Heike Bickeboller, Richard S Houlston, Maria Teresa Landi, Neil Caporaso, Angela Risch, Ali Amin Al Olama, Sonja I Berndt, Edward L Giovannucci, Henrik Gronberg, Zsofia Kote-Jarai, Jing Ma, et al.

Journal article  |  2016  |  Cancer Research

Risk factors for metachronous colorectal cancer following a primary colorectal cancer: A prospective cohort study

Harindra Jayasekara, Jeanette C Reece, Daniel D Buchanan, Christophe Rosty, S Ghazaleh Dashti, Driss Ait Ouakrim, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Graham G Giles, Dennis J Ahnen, Jan Lowery, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Susan Parry, et al.

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF CANCER

Cholecystectomy and the risk of colorectal cancer by tumor mismatch repair deficiency status

Jie Shang, Jeanette C Reece, Daniel D Buchanan, Graham G Giles, Jane C Figueiredo, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2016  |  International Journal of Colorectal Disease

Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer

David Jarvis, Jonathan S Mitchell, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, et al.

Journal article  |  2016  |  British Journal of Cancer

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease

Giulia Orlando, Philip J Law, Kimmo Palin, Sari Tuupanen, Alexandra Gylfe, Ulrika A Hanninen, Tatiana Cajuso, Tomas Tanskanen, Johanna Kondelin, Eevi Kaasinen, Antti-Pekka Sarin, Jaakko Kaprio, Johan G Eriksson, Harri Rissanen, Paul Knekt, Eero Pukkala, Pekka Jousilahti, Veikko Salomaa, Samuli Ripatti, Aarno Palotie, et al.

Journal article  |  2016  |  Human Molecular Genetics

Multivitamin, calcium and folic acid supplements and the risk of colorectal cancer in Lynch syndrome

Rowena Chau, Seyedeh Ghazaleh Dashti, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Finlay A Macrae, Alex Boussioutas, Susan Parry, Jane C Figueiredo, A Joan Levine, Dennis J Ahnen, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Stephen N Thibodeau, et al.

Journal article  |  2016  |  International Journal of Epidemiology

Determining the familial risk distribution of colorectal cancer: a data mining approach

Rowena Chau, Mark A Jenkins, Daniel D Buchanan, Driss Ait Ouakrim, Graham G Giles, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Polly A Newcomb, Noralane M Lindor, John L Hopper, Aung Ko Win

Journal article  |  2016  |  Familial Cancer

GWASeq: targeted re-sequencing follow up to GWAS

Matthew P Salomon, Wai Lok Sibon Li, Christopher K Edlund, John Morrison, Barbara K Fortini, Aung Ko Win, David V Conti, Duncan C Thomas, David Duggan, Daniel D Buchanan, Mark A Jenkins, John L Hopper, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, Graham Casey, Paul Marjoram

Journal article  |  2016  |  BMC Genomics

Promoter methylation of ITF2, but not APC, is associated with microsatellite instability in two populations of colorectal cancer patients

Andrea J Savio, Darshana Daftary, Elizabeth Dicks, Daniel D Buchanan, Patrick S Parfrey, Joanne P Young, Daniel Weisenberger, Roger C Green, Steven Gallinger, John R McLaughlin, Julia A Knight, Bharati Bapat

Journal article  |  2016  |  BMC Cancer

Comparison of Prediction Models for Lynch Syndrome Among Individuals With Colorectal Cancer

Fay Kastrinos, Rohit P Ojha, Celine Leenen, Carmelita Alvero, Rowena C Mercado, Judith Balmana, Irene Valenzuela, Francesc Balaguer, Roger Green, Noralane M Lindor, Stephen N Thibodeau, Polly Newcomb, Aung Ko Win, Mark Jenkins, Daniel D Buchanan, Lucio Bertario, Paola Sala, Heather Hampel, Sapna Syngal, Ewout W Steyerberg

Journal article  |  2016  |  JNCI: Journal of the National Cancer Institute

Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort

Christophe Rosty, Mark Clendenning, Michael D Walsh, Stine V Eriksen, Melissa C Southey, Ingrid M Winship, Finlay A Macrae, Alex Boussioutas, Nicola K Poplawski, Susan Parry, Julie Arnold, Joanne P Young, Graham Casey, Robert W Haile, Steven Gallinger, Loic Le Marchand, Polly A Newcomb, John D Potter, Melissa DeRycke, Noralane M Lindor, et al.

Journal article  |  2016  |  BMJ Open

Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening

Mark A Jenkins, Enes Makalic, James G Dowty, Daniel F Schmidt, Gillian S Dite, Robert J MacInnis, Driss Ait Ouakrim, Mark Clendenning, Louisa B Flander, Oliver K Stanesby, John L Hopper, Aung K Win, Daniel D Buchanan

Journal article  |  2016  |  Future Oncology

Clinicopathologic Risk Factor Distributions for MLH1 Promoter Region Methylation in CIMP-Positive Tumors

A Joan Levine, Amanda I Phipps, John A Baron, Daniel D Buchanan, Dennis J Ahnen, Stacey A Cohen, Noralane M Lindor, Polly A Newcomb, Christophe Rosty, Robert W Haile, Peter W Laird, Daniel J Weisenberger

Journal article  |  2016  |  Cancer Epidemiology Biomarkers & Prevention

Lynch syndrome and cervical cancer

Yoland C Antill, James G Dowty, Aung Ko Win, Tina Thompson, Michael D Walsh, Margaret C Cummings, Steven Gallinger, Noralane M Lindor, Loic Le Marchand, John L Hopper, Polly A Newcomb, Robert W Haile, James Church, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Ingrid M Winship, Mark A Jenkins

Journal article  |  2015  |  International Journal of Cancer

Childhood cancers in families with and without Lynch syndrome

John A Heath, Jeanette C Reece, Daniel D Buchanan, Graham Casey, Carol A Durno, Steven Gallinger, Robert W Haile, Polly A Newcomb, John D Potter, Stephen N Thibodeau, Loic Le Marchand, Noralane M Lindor, John L Hopper, Mark A Jenkins, Aung Ko Win

Journal article  |  2015  |  Familial Cancer

Risk of colorectal cancer for people with a mutation in both a MUTYH and a DNA mismatch repair gene

Aung Ko Win, Jeanette C Reece, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Sean P Cleary, Hyeja Kim, Michelle Cotterchio, James G Dowty, Robert J MacInnis, Katherine M Tucker, Ingrid M Winship, Finlay A Macrae, Terrilea Burnett, Loic Le Marchand, Graham Casey, Robert W Haile, Polly A Newcomb, Stephen N Thibodeau, Noralane M Lindor, et al.

Journal article  |  2015  |  Familial Cancer

Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1

Timothy HT Cheng, Deborah Thompson, Jodie Painter, Tracy O'Mara, Maggie Gorman, Lynn Martin, Claire Palles, Angela Jones, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, Polly A Newcomb, Steve Gallinger, David Conti, Fred Schumacher, Graham Casey, Graham G Giles, Paul Pharoah, et al.

Journal article  |  2015  |  Scientific Reports

Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.

Aung Ko Win, Mark Clendenning, William Crawford, Christophe Rosty, Susan G Preston, Melissa C Southey, Susan Parry, Graham G Giles, Finlay A Macrae, Ingrid M Winship, John A Baron, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2015  |  Genes & Cancer

Lynch syndrome is an inherited cancer-predisposing disorder caused by germline mutations in the DNA mismatch repair (MMR) genes bu..

Aspirin, Ibuprofen, and the Risk for Colorectal Cancer in Lynch Syndrome

Driss Ait Ouakrim, Seyedeh Ghazaleh Dashti, Rowena Chau, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Ingrid M Winship, Joanne P Young, Graham G Giles, Barbara Leggett, Finlay A Macrae, Dennis J Ahnen, Graham Casey, Steven Gallinger, Robert W Haile, Loic Le Marchand, Stephen N Thibodeau, Noralane M Lindor, Polly A Newcomb, John D Potter, et al.

Journal article  |  2015  |  Journal of the National Cancer Institute

Association between Body Mass Index and Mortality for Colorectal Cancer Survivors: Overall and by Tumor Molecular Phenotype

Peter T Campbell, Christina C Newton, Polly A Newcomb, Amanda I Phipps, Dennis J Ahnen, John A Baron, Daniel D Buchanan, Graham Casey, Sean P Cleary, Michelle Cotterchio, Alton B Farris, Jane C Figueiredo, Steven Gallinger, Roger C Green, Robert W Haile, John L Hopper, Mark A Jenkins, Loic Le Marchand, Karen W Makar, John R McLaughlin, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome

Seyedeh Ghazaleh Dashti, Rowena Chau, Driss Ait Ouakrim, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Ingrid M Winship, Julie Arnold, Dennis J Ahnen, Robert W Haile, Graham Casey, Steven Gallinger, Stephen N Thibodeau, Noralane M Lindor, Loic Le Marchand, Polly A Newcomb, John D Potter, John A Baron, John L Hopper, Mark A Jenkins, et al.

Journal article  |  2015  |  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prediagnostic Physical Activity and Colorectal Cancer Survival: Overall and Stratified by Tumor Characteristics

Sheetal Hardikar, Polly A Newcomb, Peter T Campbell, Aung Ko Win, Noralane M Lindor, Daniel D Buchanan, Karen W Makar, Mark A Jenkins, John D Potter, Amanda I Phipps

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Consequences of germline variation disrupting the constitutional translational initiation codon start sites of MLH1 and BRCA2: Use of potential alternative start sites and implications for predicting variant pathogenicity

Michael T Parsons, Phillip J Whiley, Jonathan Beesley, Mark Drost, Niels de Wind, Bryony A Thompson, Louise Marquart, John L Hopper, Mark A Jenkins, Melissa A Brown, Kathy Tucker, Linda Warwick, Daniel D Buchanan, Amanda B Spurdle

Journal article  |  2015  |  Molecular Carcinogenesis

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer (vol 5, 10442, 2015)

Nada A Al-Tassan, Nicola Whiffin, Fay J Hosking, Claire Palles, Susan M Farrington, Sara E Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F Meyer, Salma M Wakil, Ben Kinnersley, Harry Campbell, Lynn Martin, Christopher G Smith, Shelley Idziaszczyk, Ella Barclay, Timothy S Maughan, Richard Kaplan, Rachel Kerr, et al.

Journal article  |  2015  |  Scientific Reports

A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer

Nada A Al-Tassan, Nicola Whiffin, Fay J Hosking, Claire Palles, Susan M Farrington, Sara E Dobbins, Rebecca Harris, Maggie Gorman, Albert Tenesa, Brian F Meyer, Salma M Wakil, Ben Kinnersley, Harry Campbell, Lynn Martin, Christopher G Smith, Shelley Idziaszczyk, Ella Barclay, Timothy S Maughan, Richard Kaplan, Rachel Kerr, et al.

Journal article  |  2015  |  Scientific Reports

Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer in the Colon Cancer Family Registry

Matthew B Yurgelun, Serena Masciari, Victoria A Joshi, Rowena C Mercado, Noralane M Lindor, Steven Gallinger, John L Hopper, Mark A Jenkins, Daniel D Buchanan, Polly A Newcomb, John D Potter, Robert W Haile, Raju Kucherlapati, Sapna Syngal

Journal article  |  2015  |  JAMA Oncology

Association of the Colorectal CpG Island Methylator Phenotype with Molecular Features, Risk Factors, and Family History

Daniel J Weisenberger, A Joan Levine, Tiffany I Long, Daniel D Buchanan, Rhiannon Walters, Mark Clendenning, Christophe Rosty, Amit D Joshi, Mariana C Stern, Loic Le Marchand, Noralane M Lindor, Darshana Daftary, Steven Gallinger, Teresa Selander, Bharati Bapat, Polly A Newcomb, Peter T Campbell, Graham Casey, Dennis J Ahnen, John A Baron, et al.

Journal article  |  2015  |  Cancer Epidemiology Biomarkers & Prevention

Do serrated neoplasms of the small intestine represent a distinct entity? Pathological findings and molecular alterations in a series of 13 cases

Christophe Rosty, Catherine Campbell, Mark Clendenning, Mark Bettington, Daniel D Buchanan, Ian S Brown

Journal article  |  2015  |  Histopathology

Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives

Aung Ko Win, Daniel D Buchanan, Christophe Rosty, Robert J MacInnis, James G Dowty, Gillian S Dite, Graham G Giles, Melissa C Southey, Joanne P Young, Mark Clendenning, Michael D Walsh, Rhiannon J Walters, Alex Boussioutas, Thomas C Smyrk, Stephen N Thibodeau, John A Baron, John D Potter, Polly A Newcomb, Loic Le Marchand, Robert W Haile, et al.

Journal article  |  2015  |  Gut

Association Between Molecular Subtypes of Colorectal Cancer and Patient Survival

Amanda I Phipps, Paul J Limburg, John A Baron, Andrea N Burnett-Hartman, Daniel J Weisenberger, Peter W Laird, Frank A Sinicrope, Christophe Rosty, Daniel D Buchanan, John D Potter, Polly A Newcomb

Journal article  |  2015  |  Gastroenterology

High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry

Christophe Rosty, Michael D Walsh, Noralane M Lindor, Stephen N Thibodeau, Erin Mundt, Steven Gallinger, Melyssa Aronson, Aaron Pollett, John A Baron, Sally Pearson, Mark Clendenning, Rhiannon J Walters, Belinda N Nagler, William J Crawford, Joanne P Young, Ingrid Winship, Aung Ko Win, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2014  |  Familial Cancer

Tumour MLH1 promoter region methylation testing is an effective prescreen for Lynch Syndrome (HNPCC)

K Newton, NM Jorgensen, AJ Wallace, DD Buchanan, F Lalloo, RFT McMahon, J Hill, DG Evans

Journal article  |  2014  |  Journal of Medical Genetics

MISMATCH PROTEIN REPAIR (MMR) STATUS AND ENDOMETRIAL CANCER AETIOLOGY AND SURVIVAL

P Webb, Y Tan, CM Nagle, D Buchanan, AB Spurdle, A Obermair

Conference Proceedings  |  2014  |  INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

A novel colorectal cancer risk locus at 4q32.2 identified from an international genome-wide association study

Stephanie L Schmit, Fredrick R Schumacher, Christopher K Edlund, David V Conti, Leon Raskin, Flavio Lejbkowicz, Mila Pinchev, Hedy S Rennert, Mark A Jenkins, John L Hopper, Daniel D Buchanan, Noralane M Lindor, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, Shu-Chen Huang, Gad Rennert, Graham Casey, Stephen B Gruber

Journal article  |  2014  |  Carcinogenesis

Association between hypermethylation of DNA repetitive elements in white blood cell DNA and pancreatic cancer

Rachel E Neale, Paul J Clark, Jonathan Fawcett, Lin Fritschi, Belinda N Nagler, Harvey A Risch, Rhiannon J Walters, William J Crawford, Penelope M Webb, David C Whiteman, Daniel D Buchanan

Journal article  |  2014  |  Cancer Epidemiology

Should the grading of colorectal adenocarcinoma include microsatellite instability status?

Christophe Rosty, Elizabeth J Williamson, Mark Clendenning, Rhiannon J Walters, Aung K Win, Mark A Jenkins, John L Hopper, Ingrid M Winship, Melissa C Southey, Graham G Giles, Dallas R English, Daniel D Buchanan

Journal article  |  2014  |  Human Pathology

The Intestinal Epithelial Cell Differentiation Marker Intestinal Alkaline Phosphatase (ALPi) Is Selectively Induced by Histone Deacetylase Inhibitors (HDACi) in Colon Cancer Cells in a Kruppel-like Factor 5 (KLF5)-dependent Manner

Joongho Shin, Azadeh Carr, Georgia A Corner, Lars Toegel, Mercedes Davaos-Salas, Tran Hoanh, Anderly C Chueh, Sheren Al-Obaidi, Fiona Chionh, Naseem Ahmed, Daniel DY Buchanan, Joanne P Young, Madhu S Malo, Richard A Hodin, Diego Arango, Oliver M Sieber, Leonard H Augenlicht, Amardeep S Dhillon, Thomas K Weber, John M Mariadason

Journal article  |  2014  |  Journal of Biological Chemistry

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis

Nicola Whiffin, Fay J Hosking, Susan M Farrington, Claire Palles, Sara E Dobbins, Lina Zgaga, Amy Lloyd, Ben Kinnersley, Maggie Gorman, Albert Tenesa, Peter Broderick, Yufei Wang, Ella Barclay, Caroline Hayward, Lynn Martin, Daniel D Buchanan, Aung Ko Win, John Hopper, Mark Jenkins, Noralane M Lindor, et al.

Journal article  |  2014  |  Human Molecular Genetics

Re: Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication

Christophe Rosty, Elizabeth J Wiliamson, Mark Clendening, Rhianon J Walters, Michael D Walsh, Aung K Win, Mark A Jenkins, John L Hoper, Ingrid Winship, Melisa C Southey, Graham G Giles, Dalas R English, Daniel D Buchanan

Journal article  |  2014  |  JNCI Journal of the National Cancer Institute

Characterisation of Familial Colorectal Cancer Type X, Lynch syndrome, and non-familial colorectal cancer

S Shiovitz, WK Copeland, MN Passarelli, AN Burnett-Hartman, WM Grady, JD Potter, S Gallinger, DD Buchanan, C Rosty, AK Win, M Jenkins, SN Thibodeau, R Haile, JA Baron, LL Marchand, PA Newcomb, NM Lindor

Journal article  |  2014  |  British Journal of Cancer

Equality in Lynch Syndrome Screening: Why Should We Hold Patients With Endometrial Cancer to a Different Standard? Reply

Daniel D Buchanan, Yen Y Tan, Michael D Walsh, Mark Clendenning, Alexander M Metcalf, Kaltin Ferguson, Sven T Arnold, Bryony A Thompson, Felicity A Lose, Michael T Parsons, Rhiannon J Walters, Sally-Ann Pearson, Margaret Cummings, Martin K Oehler, Penelope B Blomfield, Michael A Quinn, Judy A Kirk, Colin J Stewart, Andreas Obermair, Joanne P Young, et al.

Journal article  |  2014  |  Journal of Clinical Oncology

Colorectal Cancer Cell Lines Are Representative Models of the Main Molecular Subtypes of Primary Cancer

Dmitri Mouradov, Clare Sloggett, Robert N Jorissen, Christopher G Love, Shan Li, Antony W Burgess, Diego Arango, Robert L Strausberg, Daniel Buchanan, Samuel Wormald, Liam O'Connor, Jennifer L Wilding, David Bicknell, Ian PM Tomlinson, Walter F Bodmer, John M Mariadason, Oliver M Sieber

Journal article  |  2014  |  Cancer Research

Risk of Colorectal Cancer for Carriers of Mutations in MUTYH, With and Without a Family History of Cancer

Aung Ko Win, James G Dowty, Sean P Cleary, Hyeja Kim, Daniel D Buchanan, Joanne P Young, Mark Clendenning, Christophe Rosty, Robert J MacInnis, Graham G Giles, Alex Boussioutas, Finlay A Macrae, Susan Parry, Jack Goldblatt, John A Baron, Terrilea Burnett, Loic Le Marchand, Polly A Newcomb, Robert W Haile, John L Hopper, et al.

Journal article  |  2014  |  Gastroenterology

The Association of Telomere Length with Colorectal Cancer Differs by the Age of Cancer Onset

Lisa A Boardman, Kristin Litzelman, Songwon Seo, Ruth A Johnson, Russell J Vanderboom, Grace W Kimmel, Julie M Cunningham, Ronald E Gangnon, Corinne D Engelman, Douglas L Riegert-Johnson, John Potter, Robert Haile, Daniel Buchanan, Mark A Jenkins, David N Rider, Stephen N Thibodeau, Gloria M Petersen, Halcyon G Skinner

Journal article  |  2014  |  Clinical and Translational Gastroenterology

Pooled analysis of iron-related genes in Parkinson's disease: Association with transferrin

Shannon L Rhodes, Daniel D Buchanan, Ismay Ahmed, Kent D Taylor, Marie-Anne Loriot, Janet S Sinsheimer, Jeff M Bronstein, Alexis Elbaz, George D Mellick, Jerome I Rotter, Beate Ritz

Journal article  |  2014  |  Neurobiology of Disease

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

Bryony A Thompson, Amanda B Spurdle, John-Paul Plazzer, Marc S Greenblatt, Kiwamu Akagi, Fahd Al-Mulla, Bharati Bapat, Inge Bernstein, Gabriel Capella, Johan T den Dunnen, Desiree du Sart, Aurelie Fabre, Michael P Farrell, Susan M Farrington, Ian M Frayling, Thierry Frebourg, David E Goldgar, Christopher D Heinen, Elke Holinski-Feder, Maija Kohonen-Corish, et al.

Journal article  |  2014  |  Nature Genetics

Molecular subtypes of colorectal cancer in relation to disease survival

Amanda I Phipps, Paul J Limburg, John A Baron, Andrea N Burnett-Hartman, Daniel J Weisenberger, Peter W Laird, Frank A Sinicrope, Christophe Rosty, Daniel D Buchanan, John D Potter, Polly A Newcomb

Conference Proceedings  |  2014  |  Journal of Clinical Oncology

Tumor Mismatch Repair Immunohistochemistry and DNA MLH1 Methylation Testing of Patients With Endometrial Cancer Diagnosed at Age Younger Than 60 Years Optimizes Triage for Population-Level Germline Mismatch Repair Gene Mutation Testing

Daniel D Buchanan, Yen Y Tan, Michael D Walsh, Mark Clendenning, Alexander M Metcalf, Kaltin Ferguson, Sven T Arnold, Bryony A Thompson, Felicity A Lose, Michael T Parsons, Rhiannon J Walters, Sally-Ann Pearson, Margaret Cummings, Martin K Oehler, Penelope B Blomfield, Michael A Quinn, Judy A Kirk, Colin J Stewart, Andreas Obermair, Joanne P Young, et al.

Journal article  |  2014  |  Journal of Clinical Oncology

Clinical problems of colorectal cancer and endometrial cancer cases with unknown cause of tumor mismatch repair deficiency (suspected Lynch syndrome).

Daniel D Buchanan, Christophe Rosty, Mark Clendenning, Amanda B Spurdle, Aung Ko Win

Journal article  |  2014  |  Application of Clinical Genetics

Carriers of a germline mutation in one of the DNA mismatch repair (MMR) genes have a high risk of developing numerous different ca..

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype

Michael D Walsh, Mark Clendenning, Elizabeth Williamson, Sally-Ann Pearson, Rhiannon J Walters, Belinda Nagler, David Packenas, Aung K Win, John L Hopper, Mark A Jenkins, Andrew M Haydon, Christophe Rosty, Dallas R English, Graham G Giles, Michael A McGuckin, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Telomere Length Varies By DNA Extraction Method: Implications for Epidemiologic Research

Julie M Cunningham, Ruth A Johnson, Kristin Litzelman, Halcyon G Skinner, Songwon Seo, Corinne D Engelman, Russell J Vanderboom, Grace W Kimmel, Ronald E Gangnon, Douglas L Riegert-Johnson, John A Baron, John D Potter, Robert Haile, Daniel D Buchanan, Mark A Jenkins, David N Rider, Stephen N Thibodeau, Gloria M Petersen, Lisa A Boardman

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

BRAFV600E Immunohistochemistry Facilitates Universal Screening of Colorectal Cancers for Lynch Syndrome

Christopher W Toon, Michael D Walsh, Angela Chou, David Capper, Adele Clarkson, Loretta Sioson, Stephen Clarke, Scott Mead, Rhiannon J Walters, Mark Clendenning, Christophe Rosty, Joanne P Young, Aung Ko Win, John L Hopper, Ashley Crook, Andreas von Deimling, Mark A Jenkins, Daniel D Buchanan, Anthony J Gill

Journal article  |  2013  |  American Journal of Surgical Pathology

Immunophenotypic analysis of ovarian endometrioid adenocarcinoma: correlation with KRAS mutation and the presence of endometriosis

Colin JR Stewart, Michael D Walsh, Charley A Budgeon, Maxine L Crook, Daniel B Buchanan

Journal article  |  2013  |  Pathology

Detection of large scale 3 ' deletions in the PMS2 gene amongst Colon-CFR participants: have we been missing anything?

Mark Clendenning, Michael D Walsh, Judith Balmana Gelpi, Stephen N Thibodeau, Noralane Lindor, John D Potter, Polly Newcomb, Loic LeMarchand, Robert Haile, Steve Gallinger, John L Hopper, Mark A Jenkins, Christophe Rosty, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Familial Cancer

Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer

Mohammad R Akbari, Laura N Anderson, Daniel D Buchanan, Mark Clendenning, Mark A Jenkins, Aung Ko Win, John L Hopper, Graham G Giles, Robert Nam, Steven Narod, Steven Gallinger, Sean P Cleary

Journal article  |  2013  |  Cancer Epidemiology

Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins

Michael D Walsh, Margaret C Cummings, Sally-Ann Pearson, Mark Clendenning, Rhiannon J Walters, Belinda Nagler, John L Hopper, Mark A Jenkins, Graeme K Suthers, Jack Goldblatt, Kathy Tucker, Michael R Gattas, Julie L Arnold, Susan Parry, Finlay A Macrae, Michael A McGuckin, Joanne P Young, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Association between hypermethylation of DNA repetitive elements in white blood cell DNA and early-onset colorectal cancer

Rhiannon J Walters, Elizabeth J Williamson, Dallas R English, Joanne P Young, Christophe Rosty, Mark Clendenning, Michael D Walsh, Susan Parry, Dennis J Ahnen, John A Baron, Aung Ko Win, Graham G Giles, John L Hopper, Mark A Jenkins, Daniel D Buchanan

Journal article  |  2013  |  Epigenetics

Identification of Novel Variants in Colorectal Cancer Families by High-Throughput Exome Sequencing

Melissa S DeRycke, Shanaka R Gunawardena, Sumit Middha, Yan W Asmann, Daniel J Schaid, Shannon K McDonnell, Shaun M Riska, Bruce W Eckloff, Julie M Cunningham, Brooke L Fridley, Daniel J Serie, William R Bamlet, Mine S Cicek, Mark A Jenkins, David J Duggan, Daniel Buchanan, Mark Clendenning, Robert W Haile, Michael O Woods, Steven N Gallinger, et al.

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome

Mark Clendenning, Joanne P Young, Michael D Walsh, Sonja Woodall, Julie Arnold, Mark Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Steven Gallinger, Christophe Rosty, Susan Parry, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

Improving identification of lynch syndrome patients: A comparison of research data with clinical records

Yen Y Tan, Julie McGaughran, Kaltin Ferguson, Michael D Walsh, Daniel D Buchanan, Joanne P Young, Penelope M Webb, Andreas Obermair, Amanda B Spurdle

Journal article  |  2013  |  International Journal of Cancer

PIK3CA Activating Mutation in Colorectal Carcinoma: Associations with Molecular Features and Survival

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Kristy Sanderson, Rhiannon J Walters, Susan Parry, Mark A Jenkins, Aung Ko Win, Melissa C Southey, John L Hopper, Graham G Giles, Elizabeth J Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  PLoS One

Risk of Metachronous Colon Cancer Following Surgery for Rectal Cancer in Mismatch Repair Gene Mutation Carriers

Aung Ko Win, Susan Parry, Bryan Parry, Matthew F Kalady, Finlay A Macrae, Dennis J Ahnen, Graeme P Young, Lara Lipton, Ingrid Winship, Alex Boussioutas, Joanne P Young, Daniel D Buchanan, Julie Arnold, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Noralane M Lindor, Steven Gallinger, John L Hopper, Mark A Jenkins

Journal article  |  2013  |  Annals of Surgical Oncology

Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features

Christophe Rosty, Joanne P Young, Michael D Walsh, Mark Clendenning, Rhiannon J Walters, Sally Pearson, Erika Pavluk, Belinda Nagler, David Pakenas, Jeremy R Jass, Mark A Jenkins, Aung Ko Win, Melissa C Southey, Susan Parry, John L Hopper, Graham G Giles, Elizabeth Williamson, Dallas R English, Daniel D Buchanan

Journal article  |  2013  |  Modern Pathology

Absence of PMS2 mutations in colon-CFR participants whose colorectal cancers demonstrate unexplained loss of MLH1 expression

M Clendenning, FA Macrae, MD Walsh, RJ Walters, SN Thibodeau, SR Gunawardena, JD Potter, RW Haile, S Gallinger, JL Hopper, MA Jenkins, C Rosty, JP Young, DD Buchanan

Journal article  |  2013  |  Clinical Genetics

Family History of Colorectal Cancer in BRAF p.V600E-Mutated Colorectal Cancer Cases

Daniel D Buchanan, Aung K Win, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Belinda Nagler, Sally-Ann Pearson, Finlay A Macrae, Susan Parry, Julie Arnold, Ingrid Winship, Graham G Giles, Noralane M Lindor, John D Potter, John L Hopper, Christophe Rosty, Joanne P Young, Mark A Jenkins

Journal article  |  2013  |  Cancer Epidemiology, Biomarkers & Prevention

Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

Aung Ko Win, John L Hopper, Daniel D Buchanan, Joanne P Young, Albert Tenesa, James G Dowty, Graham G Giles, Jack Goldblatt, Ingrid Winship, Alex Boussioutas, Graeme P Young, Susan Parry, John A Baron, David Duggan, Steven Gallinger, Polly A Newcomb, Robert W Haile, Loic Le Marchand, Noralane M Lindor, Mark A Jenkins

Journal article  |  2013  |  European Journal of Cancer

KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers

AI Phipps, DD Buchanan, KW Makar, AK Win, JA Baron, NM Lindor, JD Potter, PA Newcomb

Journal article  |  2013  |  British Journal of Cancer

DNA mismatch repair deficiency in sebaceous skin tumors: a large case series from a single pathology practice

Michael D Walsh, Rhonda J Edwards, Kevin J Whitehead, Michael R Gattas, Daniel D Buchanan

Conference Proceedings  |  2013  |  Epidemiology

Multiplicity and Molecular Heterogeneity of Colorectal Carcinomas in Individuals With Serrated Polyposis

Christophe Rosty, Michael D Walsh, Rhiannon J Walters, Mark Clendenning, Sally-Ann Pearson, Mark A Jenkins, Aung Ko Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Kathy Tucker, Sian Greening, Michael R Gattas, Sonja Woodall, Julie Arnold, Neal I Walker, Susan Parry, et al.

Journal article  |  2013  |  American Journal of Surgical Pathology

Cancer Risks for MLH1 and MSH2 Mutation Carriers

James G Dowty, Aung K Win, Daniel D Buchanan, Noralane M Lindor, Finlay A Macrae, Mark Clendenning, Yoland C Antill, Stephen N Thibodeau, Graham Casey, Steve Gallinger, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Graeme P Young, Paul A James, Graham G Giles, Shanaka R Gunawardena, Barbara A Leggett, Michael Gattas, Alex Boussioutas, et al.

Journal article  |  2013  |  Human Mutation

Risks of Colorectal and Other Cancers After Endometrial Cancer for Women With Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Ingrid Winship, Katherine M Tucker, Daniel D Buchanan, Joanne P Young, Christophe Rosty, Barbara Leggett, Graham G Giles, Jack Goldblatt, Finlay A Macrae, Susan Parry, Matthew F Kalady, John A Baron, Dennis J Ahnen, Loic Le Marchand, Steven Gallinger, Robert W Haile, Polly A Newcomb, John L Hopper, et al.

Journal article  |  2013  |  Journal of the National Cancer Institute

A Multifactorial Likelihood Model for MMR Gene Variant Classification Incorporating Probabilities Based on Sequence Bioinformatics and Tumor Characteristics: A Report from the Colon Cancer Family Registry

Bryony A Thompson, David E Goldgar, Carol Paterson, Mark Clendenning, Rhiannon Walters, Sven Arnold, Michael T Parsons, Michael D Walsh, Steven Gallinger, Robert W Haile, John L Hopper, Mark A Jenkins, Loic LeMarchand, Noralane M Lindor, Polly A Newcomb, Stephen N Thibodeau, Joanne P Young, Daniel D Buchanan, Sean V Tavtigian, Amanda B Spurdle

Journal article  |  2013  |  Human Mutation

Genome-Wide Search for Gene-Gene Interactions in Colorectal Cancer

Shuo Jiao, Li Hsu, Sonja Berndt, Stephane Bezieau, Hermann Brenner, Daniel Buchanan, Bette J Caan, Peter T Campbell, Christopher S Carlson, Graham Casey, Andrew T Chan, Jenny Chang-Claude, Stephen Chanock, David V Conti, Keith R Curtis, David Duggan, Steven Gallinger, Stephen B Gruber, Tabitha A Harrison, Richard B Hayes, et al.

Journal article  |  2012  |  PLoS One

Identification of Lynch Syndrome Among Patients With Colorectal Cancer

Leticia Moreira, Francesc Balaguer, Noralane Lindor, Albert de la Chapelle, Heather Hampel, Lauri A Aaltonen, John L Hopper, Loic Le Marchand, Steven Gallinger, Polly A Newcomb, Robert Haile, Stephen N Thibodeau, Shanaka Gunawardena, Mark A Jenkins, Daniel D Buchanan, John D Potter, John A Baron, Dennis J Ahnen, Victor Moreno, Montserrat Andreu, et al.

Journal article  |  2012  |  JAMA: Journal of the American Medical Association

BRAF Mutation Status and Survival after Colorectal Cancer Diagnosis According to Patient and Tumor Characteristics

Amanda I Phipps, Daniel D Buchanan, Karen W Makar, Andrea N Burnett-Hartman, Anna E Coghill, Michael N Passarelli, John A Baron, Dennis J Ahnen, Aung Ko Win, John D Potter, Polly A Newcomb

Journal article  |  2012  |  Cancer Epidemiology, Biomarkers & Prevention

Risks of Primary Extracolonic Cancers Following Colorectal Cancer in Lynch Syndrome

Aung Ko Win, Noralane M Lindor, Joanne P Young, Finlay A Macrae, Graeme P Young, Elizabeth Williamson, Susan Parry, Jack Goldblatt, Lara Lipton, Ingrid Winship, Barbara Leggett, Katherine M Tucker, Graham G Giles, Daniel D Buchanan, Mark Clendenning, Christophe Rosty, Julie Arnold, A Joan Levine, Robert W Haile, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of the National Cancer Institute

KRAS mutations in ovarian low-grade endometrioid adenocarcinoma: association with concurrent endometriosis

Colin JR Stewart, Yee Leung, Michael D Walsh, Rhiannon J Walters, Joanne P Young, Daniel D Buchanan

Journal article  |  2012  |  Human Pathology

Body size and risk for colorectal cancers showing BRAF mutations or microsatellite instability: a pooled analysis

Laura AE Hughes, Elizabeth J Williamson, Manon van Engeland, Mark A Jenkins, Graham G Giles, John L Hopper, Melissa C Southey, Joanne P Young, Daniel D Buchanan, Michael D Walsh, Piet A van den Brandt, R Alexandra Goldbohm, Matty P Weijenberg, Dallas R English

Journal article  |  2012  |  International Journal of Epidemiology

Phenotype and Polyp Landscape in Serrated Polyposis Syndrome: A Series of 100 Patients From Genetics Clinics

Christophe Rosty, Daniel D Buchanan, Michael D Walsh, Sally-Ann Pearson, Erika Pavluk, Rhiannon J Walters, Mark Clendenning, Kevin J Spring, Mark A Jenkins, Aung K Win, John L Hopper, Kevin Sweet, Wendy L Frankel, Melyssa Aronson, Steve Gallinger, Jack Goldblatt, Sonja Woodall, Julie Arnold, Neal I Walker, Jeremy R Jass, et al.

Journal article  |  2012  |  American Journal of Surgical Pathology

Colorectal Cancer Linkage on Chromosomes 4q21, 8q13, 12q24, and 15q22

Mine S Cicek, Julie M Cunningham, Brooke L Fridley, Daniel J Serie, William R Bamlet, Brenda Diergaarde, Robert W Haile, Loic Le Marchand, Theodore G Krontiris, H Banfield Younghusband, Steven Gallinger, Polly A Newcomb, John L Hopper, Mark A Jenkins, Graham Casey, Fredrick Schumacher, Zhu Chen, Melissa S DeRycke, Allyson S Templeton, Ingrid Winship, et al.

Journal article  |  2012  |  PLoS One

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry

Michael D Walsh, Daniel D Buchanan, Sally-Ann Pearson, Mark Clendenning, Mark A Jenkins, Aung Ko Win, Rhiannon J Walters, Kevin J Spring, Belinda Nagler, Erika Pavluk, Sven T Arnold, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, John L Hopper, Jeremy R Jass, John A Baron, Dennis J Ahnen, Stephen N Thibodeau, et al.

Journal article  |  2012  |  Modern Pathology

Cancer Risks for Relatives of Patients With Serrated Polyposis

Aung Ko Win, Rhiannon J Walters, Daniel D Buchanan, Mark A Jenkins, Kevin Sweet, Wendy L Frankel, Albert de la Chapelle, Diane M McKeone, Michael D Walsh, Mark Clendenning, Sally-Ann Pearson, Erika Pavluk, Belinda Nagler, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, et al.

Journal article  |  2012  |  American Journal of Gastroenterology

Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study

Aung Ko Win, Joanne P Young, Noralane M Lindor, Katherine M Tucker, Dennis J Ahnen, Graeme P Young, Daniel D Buchanan, Mark Clendenning, Graham G Giles, Ingrid Winship, Finlay A Macrae, Jack Goldblatt, Melissa C Southey, Julie Arnold, Stephen N Thibodeau, Shanaka R Gunawardena, Bharati Bapat, John A Baron, Graham Casey, Steven Gallinger, et al.

Journal article  |  2012  |  Journal of Clinical Oncology

Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification

Michael T Parsons, Daniel D Buchanan, Bryony Thompson, Joanne P Young, Amanda B Spurdle

Journal article  |  2012  |  Journal of Medical Genetics

Cancer Risks for the Relatives of Colorectal Cancer Cases with a Methylated MLH1 Promoter Region: Data from the Colorectal Cancer Family Registry

A Joan Levine, Aung Ko Win, Daniel D Buchanan, Mark A Jenkins, John A Baron, Joanne P Young, Tiffany I Long, Daniel J Weisenberger, Peter W Laird, Rebecca L McCall, David J Duggan, Robert W Haile

Journal article  |  2012  |  Cancer prevention research

Using tumour pathology to identify people at high genetic risk of breast and colorectal cancers

JL Hopper, MA Jenkins, JG Dowty, GS Dite, C Apicella, L Keogh, AK Win, JP Young, D Buchanan, MD Walsh, C Rosty, L Baglietto, G Severi, KA Phillips, EM Wong, A Dobrovic, P Waring, I Winship, SJ Ramus, GG Giles, et al.

Journal article  |  2012  |  Pathology

Hyperplastic polyp of the duodenum: a report of 9 cases with immunohistochemical and molecular findings

Christophe Rosty, Daniel D Buchanan, Rhiannon J Walters, Norman J Carr, John W Bothman, Joanne P Young, Ian S Brown

Journal article  |  2011  |  Human Pathology

Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer

Aung Ko Win, Sean P Cleary, James G Dowty, John A Baron, Joanne P Young, Daniel D Buchanan, Melissa C Southey, Terrilea Burnett, Patrick S Parfrey, Roger C Green, Loic Le Marchand, Polly A Newcomb, Robert W Haile, Noralane M Lindor, John L Hopper, Steven Gallinger, Mark A Jenkins

Journal article  |  2011  |  International Journal of Cancer

Determining the frequency of de novo germline mutations in DNA mismatch repair genes

Aung Ko Win, Mark A Jenkins, Daniel D Buchanan, Mark Clendenning, Joanne P Young, Graham G Giles, Jack Goldblatt, Barbara A Leggett, John L Hopper, Stephen N Thibodeau, Noralane M Lindor

Journal article  |  2011  |  Journal of Medical Genetics

Body mass index in early adulthood and colorectal cancer risk for carriers and non-carriers of germline mutations in DNA mismatch repair genes

AK Win, JG Dowty, DR English, PT Campbell, JP Young, I Winship, FA Macrae, L Lipton, S Parry, GP Young, DD Buchanan, ME Martinez, ET Jacobs, DJ Ahnen, RW Haile, G Casey, JA Baron, NM Lindor, SN Thibodeau, PA Newcomb, et al.

Journal article  |  2011  |  British Journal of Cancer

Promoter methylation of Wnt5a is associated with microsatellite instability and BRAF V600E mutation in two large populations of colorectal cancer patients

JB Rawson, M Mrkonjic, D Daftary, E Dicks, DD Buchanan, HB Younghusband, PS Parfrey, JP Young, A Pollett, RC Green, S Gallinger, JR McLaughlin, JA Knight, B Bapat

Journal article  |  2011  |  British Journal of Cancer

Mutation deep within an intron of MSH2 causes Lynch syndrome

Mark Clendenning, Daniel D Buchanan, Michael D Walsh, Belinda Nagler, Christophe Rosty, Bryony Thompson, Amanda B Spurdle, John L Hopper, Mark A Jenkins, Joanne P Young

Journal article  |  2011  |  Familial Cancer

Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome)

Aedan Roberts, Derek Nancarrow, Mark Clendenning, Daniel D Buchanan, Mark A Jenkins, David Duggan, Darin Taverna, Diane McKeone, Rhiannon Walters, Michael D Walsh, Bruce W Young, Jeremy R Jass, Christophe Rosty, Michael Gattas, Elise Pelzer, John L Hopper, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, et al.

Journal article  |  2011  |  Familial Cancer

Quality Assessment and Correlation of Microsatellite Instability and Immunohistochemical Markers among Population- and Clinic-Based Colorectal Tumors Results from the Colon Cancer Family Registry

Mine S Cicek, Noralane M Lindor, Steven Gallinger, Bharati Bapat, John L Hopper, Mark A Jenkins, Joanne Young, Daniel Buchanan, Michael D Walsh, Loic Le Marchand, Terrilea Burnett, Polly A Newcomb, William M Grady, Robert W Haile, Graham Casey, Sarah J Plummer, Lisa A Krumroy, John A Baron, Stephen N Thibodeau

Journal article  |  2011  |  Journal of Molecular Diagnostics

Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients

James B Rawson, Michael Manno, Miralem Mrkonjic, Darshana Daftary, Elizabeth Dicks, Daniel D Buchanan, H Banfield Younghusband, Patrick S Parfrey, Joanne P Young, Aaron Pollett, Roger C Green, Steven Gallinger, John R McLaughlin, Julia A Knight, Bharati Bapat

Journal article  |  2011  |  Carcinogenesis

Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study (vol 25, pg 703, 2010)

Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Michael Gattas, Michael D Walsh, Mark Clendenning, Diane McKeone, Rhiannon Walters, Aedan Roberts, Alasdair Young, Heather Hampel, John L Hopper, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, Graeme P Young, Elizabeth Chow, et al.

Journal article  |  2010  |  International Journal of Colorectal Disease

Lynch syndrome-associated breast cancers: clinicopathological characteristics of a case series from the colon CFR

MD Walsh, MC Cummings, DD Buchanan, S Arnold, DM Mckeone, R Walters, JL Hopper, MA Jenkins, MA Mcguckin, J Young

Journal article  |  2010  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Origin of colorectal cancers in high-risk serrated neoplasia patients

MD Walsh, C Rosty, DD Buchanan, RJ Walters, A Roberts, M Clendenning, DM McKeone, NI Walker, S Parry, JP Young

Journal article  |  2010  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Linkage to chromosome 2q32.2-q35 in familial serrated neoplasia

A Roberts, D Nancarrow, M Clendenning, DD Buchanan, MA Jenkins, D Duggan, MD Walsh, S Parry, A Lindblom, JP Young

Conference Proceedings  |  2010  |  JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Risk Factors for Colorectal Cancer in Patients with Multiple Serrated Polyps: A Cross-Sectional Case Series from Genetics Clinics

Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Dallas R English, Michael D Walsh, Mark Clendenning, Diane M McKeone, Rhiannon J Walters, Aedan Roberts, Sally-Ann Pearson, Erika Pavluk, John L Hopper, Michael R Gattas, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry D Phillips, Sonja Woodall, et al.

Journal article  |  2010  |  PLoS One

Confirmation of Linkage to and Localization of Familial Colon Cancer Risk Haplotype on Chromosome 9q22

Courtney Gray-McGuire, Kishore Guda, Indra Adrianto, Chee Paul Lin, Leanna Natale, John D Potter, Polly Newcomb, Elizabeth M Poole, Cornelia M Ulrich, Noralane Lindor, Ellen L Goode, Brooke L Fridley, Robert Jenkins, Loic Le Marchand, Graham Casey, Robert Haile, John Hopper, Mark Jenkins, Joanne Young, Daniel Buchanan, et al.

Journal article  |  2010  |  Cancer Research

Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study

Daniel D Buchanan, Kevin Sweet, Musa Drini, Mark A Jenkins, Aung Ko Win, Michael Gattas, Michael D Walsh, Mark Clendenning, Diane McKeone, Rhiannon Walters, Aedan Roberts, Alasdair Young, Heather Hampel, John L Hopper, Jack Goldblatt, Jill George, Graeme K Suthers, Kerry Phillips, Graeme P Young, Elizabeth Chow, et al.

Journal article  |  2010  |  International Journal of Colorectal Disease

Lynch Syndrome-Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry

Michael D Walsh, Daniel D Buchanan, Margaret C Cummings, Sally-Ann Pearson, Sven T Arnold, Mark Clendenning, Rhiannon Walters, Diane M McKeone, Amanda B Spurdle, John L Hopper, Mark A Jenkins, Kerry D Phillips, Graeme K Suthers, Jill George, Jack Goldblatt, Amanda Muir, Kathy Tucker, Elise Pelzer, Michael R Gattas, Sonja Woodall, et al.

Journal article  |  2010  |  Clinical Cancer Research

Lynch syndrome-associated breast cancers: Clinicopathological characteristics of a case series from the Colon CFR

Christophe Rosty, Michael Walsh, Margaret Cummings, Daniel Buchanan, Sven Arnold, Diane McKeone, Rhiannon Walters, John Hopper, Mark Jenkins, Amanda Spurdle, Michael McGuckin, Sunil Lakhani, Joanne Young

Conference Proceedings  |  2010  |  Carcinogenesis

Lessons from Lynch syndrome: a tumor biology-based approach to familial colorectal cancer

Daniel D Buchanan, Aedan Roberts, Michael D Walsh, Susan Parry, Joanne P Young

Journal article  |  2010  |  Future Oncology

Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers

Laura Baglietto, Noralane M Lindor, James G Dowty, Darren M White, Anja Wagner, Encarna B Gomez Garcia, Annette HJT Vriends, Nicola R Cartwright, Rebecca A Barnetson, Susan M Farrington, Albert Tenesa, Heather Hampel, Daniel Buchanan, Sven Arnold, Joanne Young, Michael D Walsh, Jeremy Jass, Finlay Macrae, Yoland Antill, Ingrid M Winship, et al.

Journal article  |  2010  |  Journal of the National Cancer Institute

Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis

Michael D Walsh, Daniel D Buchanan, Rhiannon Walters, Aedan Roberts, Sven Arnold, Diane McKeone, Mark Clendenning, Andrew R Ruszkiewicz, Mark A Jenkins, John L Hopper, Jack Goldblatt, Jillian George, Graeme K Suthers, Kerry Phillips, Graeme P Young, Finlay Macrae, Musa Drini, Michael O Woods, Susan Parry, Jeremy R Jass, et al.

Journal article  |  2009  |  Familial Cancer

A Perspective on Bi-allelic MUTYH Mutations in Patients With Hyperplastic Polyposis Syndrome

Daniel Buchanan, Joanne Young

Journal article  |  2009  |  Gastroenterology

Classifying MLH1 and MSH2 Variants Using Bioinformatic Prediction, Splicing Assays, Segregation, and Tumor Characteristics

Sven Arnold, Daniel D Buchanan, Melissa Barker, Lesley Jaskowski, Michael D Walsh, Genevieve Birney, Michael O Woods, John L Hopper, Mark A Jenkins, Melissa A Brown, Sean V Tavtigian, David E Goldgar, Joanne P Young, Amanda B Spurdle

Journal article  |  2009  |  Human Mutation

Screening PARK genes for mutations in early-onset Parkinson's disease patients from Queensland, Australia

George D Mellick, Gerhard A Siebert, Manabu Funayama, Daniel D Buchanan, Yuanzhe Li, Yoko Imamichi, Hiroyo Yoshino, Peter A Silburn, Nobutaka Hattori

Journal article  |  2009  |  Parkinsonism and Related Disorders

Molecular Characterization of MSI-H Colorectal Cancer by MLH1 Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening

Jenny N Poynter, Kimberly D Siegmund, Daniel J Weisenberger, Tiffany I Long, Stephen N Thibodeau, Noralane Lindor, Joanne Young, Mark A Jenkins, John L Hopper, John A Baron, Dan Buchanan, Graham Casey, A Joan Levine, Loic Le Marchand, Steven Gallinger, Bharati Bapat, John D Potter, Polly A Newcomb, Robert W Haile, Peter W Laird

Journal article  |  2008  |  Cancer Epidemiology, Biomarkers & Prevention

DNA mismatch repair deficiency in breast cancers arising in breast/colon families

M Walsh, M Cummings, D Buchanan, S Arnold, D McKeone, R Walters, J Jass, J Hopper, M Jenkins, A Spurdle, M McGuckin, J Young

Conference Proceedings  |  2008  |  HISTOPATHOLOGY

Ethnicity and risk for colorectal cancers showing somatic BRAF V600E mutation or CpG island methylator phenotype

Dallas R English, Joanne P Young, Julie A Simpson, Mark A Jenkins, Melissa C Southey, Michael D Walsh, Daniel D Buchanan, Melissa A Barker, Andrew M Haydon, Simon G Royce, Aedan Roberts, Susan Parry, John L Hopper, Jeremy J Jass, Graham G Giles

Journal article  |  2008  |  Cancer Epidemiology, Biomarkers & Prevention

A frame-shift mutation of PMS2 is a widespread cause of Lynch syndrome

M Clendenning, L Senter, H Hampel, K Lagerstedt Robinson, S Sun, D Buchanan, MD Walsh, M Nilbert, J Green, J Potter, A Lindblom, A de la Chapelle

Journal article  |  2008  |  Journal of Medical Genetics

Molecular, pathologic, and clinical features of early-onset endometrial cancer: Identifying presumptive lynch syndrome patients

Michael D Walsh, Margaret C Cummings, Daniel D Buchanan, Wendy M Dambacher, Sven Arnold, Diane McKeone, Rebecca Byrnes, Melissa A Barker, Barbara A Leggett, Michael Gattas, Jeremy R Jass, Amanda B Spurdle, Joanne Young, Andreas Obermair

Journal article  |  2008  |  Clinical Cancer Research

Stability of BAT26 in Lynch syndrome colorectal tumours

Lesley Jaskowski, Joanne Young, Leigh Jackson, Sven Arnold, Melissa A Barker, Michael D Walsh, Daniel D Buchanan, Samantha Holman, Kara A Mensink, Mark A Jenkins, John L Hopper, Stephen N Thibodeau, Jeremy R Jass, Amanda B Spurdle

Journal article  |  2007  |  European Journal of Human Genetics

Association of APOE with Parkinson disease age-at-onset in women

Daniel D Buchanan, Peter A Silburn, Jonathan A Prince, George D Mellick

Journal article  |  2007  |  Neurosci. Lett.

Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?

Paul K Lovelock, Amanda B Spurdle, Myth TS Mok, Daniel J Farrugia, Sunil R Lakhani, Sue Healey, Stephen Arnold, Daniel Buchanan, Fergus J Couch, Beric R Henderson, David E Goldgar, Sean V Tavtigian, Georgia Chenevix-Trench, Melissa A Brown

Journal article  |  2007  |  Breast Cancer Res.

Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis

P Minoo, K Baker, R Goswami, G Chong, WD Foulkes, AR Ruszkiewicz, M Barker, D Buchanan, J Young, JR Jass

Journal article  |  2006  |  Gut

DNA mismatch repair deficiency in early-onset endometrial carcinomas

Michael Walsh, Joanne Young, Margaret Cummings, Daniel Buchanan, Melissa Barker, Michael Gattas, Barbara Leggett, Jass Jeremy, Amanda Spurdle, Andreas Obermair

Conference Proceedings  |  2006  |  MODERN PATHOLOGY

Advanced colorectal polyps with the molecular and morphological features of serrated polyps and adenomas: concept of a 'fusion' pathway to colorectal cancer

JR Jass, K Baker, I Zlobec, T Higuchi, M Barker, D Buchanan, J Young

Journal article  |  2006  |  Histopathology

Hyperplastic polyposis syndrome: Phenotypic presentations and the role of MBD4 and MYH

Elizabeth Chow, Lara Lipton, Elly Lynch, Rebecca D'Souza, Clelia Aragona, Lindy Hodgkin, Gregor Brown, Ingrid Winship, Melissa Barker, Daniel Buchanan, Shannon Cowie, Steve Nasioulas, Desiree du Sart, Joanne Young, Barbara Leggett, Jeremy Jass, Finlay Macrae

Journal article  |  2006  |  Gastroenterology

CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

Daniel J Weisenberger, Kimberly D Siegmund, Mihaela Campan, Joanne Young, Tiffany I Long, Mark A Faasse, Gyeong Hoon Kang, Martin Widschwendter, Deborah Weener, Daniel Buchanan, Hoey Koh, Lisa Simms, Melissa Barker, Barbara Leggett, Joan Levine, Myungjin Kim, Amy J French, Stephen N Thibodeau, Jeremy Jass, Robert Haile, et al.

Journal article  |  2006  |  Nat. Genet.

DNA methylation in normal mucosa and polyps in hyperplastic polyposis of colorectum

Parham Minoo, Kristi Baker, Rashmi Goswami, George Chong, William Foulkes, Andrew Ruszkiewicz, Melissa Barker, Daniel Buchanan, Joanne Young, Jeremy Jass

Conference Proceedings  |  2006  |  CANCER RESEARCH

GSK3B polymorphisms alter transcription and splicing in Parkinson's disease

JBJ Kwok, M Hallupp, CT Loy, DKY Chan, J Woo, GD Mellick, DD Buchanan, PA Silburn, GM Halliday, PR Schofield

Journal article  |  2005  |  Ann. Neurol.

Evidence for BRAF mutation and variable levels of microsatellite instability in a syndrome of familial colorectal cancer

J Young, MA Barker, LA Simms, MD Walsh, KG Biden, D Buchanan, R Buttenshaw, VLJ Whitehall, S Arnold, L Jackson, T Kambara, KJ Spring, MA Jenkins, GJ Walker, JL Hopper, BA Leggett, JR Jass

Journal article  |  2005  |  Clinical Gastroenterology and Hepatology

Sequence variation in the proximity of IDE may impact age at onset of both Parkinson disease and Alzheimer disease

MEL Blomqvist, PA Silburn, DD Buchanan, N Andreasen, K Blennow, NL Pedersen, AJ Brookes, GD Mellick, JA Prince

Journal article  |  2004  |  Neurogenetics

Tau haplotypes regulate transcription and are associated with Parkinson's disease

JBJ Kwok, ET Teber, C Loy, M Hallupp, G Nicholson, GD Mellick, DD Buchanan, PA Silburn, PR Schofield

Journal article  |  2004  |  Annals of Neurology

The Cys282Tyr polymorphism in the HFE gene in Australian Parkinson's disease patients

DD Buchanan, PA Silburn, JB Chalk, DG Le Couteur, GD Mellick

Journal article  |  2002  |  Neurosci. Lett.

Lack of association between CYP1A1 polymorphism and Parkinson's disease in a Chinese population

DKY Chan, GD Mellick, DD Buchanan, WT Hung, PW Ng, J Woo, R Kay

Journal article  |  2002  |  Journal of Neural Transmission

The parkin gene S/N167 polymorphism in Australian Parkinson's disease patients and controls

GD Mellick, DD Buchanan, N Hattori, AJ Brookes, Y Mizuno, DG Le Couteur, PA Silburn

Journal article  |  2001  |  Parkinsonism Relat. Disord.

The monoamine oxidase B gene GT repeat polymorphism and Parkinson's disease in a Chinese population

GD Mellick, DD Buchanan, PA Silburn, DKY Chan, DG Le Couteur, LK Law, J Woo, CP Pang

Journal article  |  2000  |  Journal of Neurology

Variations in the monoamine oxidase B (MAOB) gene are associated with Parkinson's disease

GD Mellick, DD Buchanan, SJ McCann, KM James, AG Johnson, DR Davis, N Liyou, D Chan, DG Le Couteur

Journal article  |  1999  |  Movement Disorders

The ACE deletion polymorphism is not associated with Parkinson's disease

GD Mellick, DD Buchanan, SJ McCann, DR Davis, DG Le Couteur, D Chan, AG Johnson

Journal article  |  1999  |  European Neurology