Tom Karagiannis

Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy

Nadia Mazarakis, Jitraporn Vongsvivut, Keith R Bambery, Katherine Ververis, Mark J Tobin, Simon G Royce, Chrishan S Samuel, Kenneth J Snibson, Paul V Licciardi, Tom C Karagiannis

Journal article  |  2020  |  Scientific Reports

The ovalbumin-induced (OVA) chronic allergic airways murine model is a well-established model for investigating pre-clinical thera..

Investigation of potential anti-pneumococcal effects of L-sulforaphane and metabolites: Insights from synchrotron-FTIR microspectroscopy and molecular docking studies

Julia Liang, Anita Mantelos, Zheng Quan Toh, Stephanie M Tortorella, Katherine Ververis, Jitraporn Vongsvivut, Keith R Bambery, Paul Licciardi, Andrew Hung, Tom C Karagiannis

Journal article  |  2020  |  Journal of Molecular Graphics and Modelling

Streptococcus pneumoniae infection can lead to pneumococcal disease, a major cause of mortality in children under the age of five ..

The potential use of L-sulforaphane for the treatment of chronic inflammatory diseases: A review of the clinical evidence

Nadia Mazarakis, Kenneth Snibson, Paul V Licciardi, Tom C Karagiannis

Journal article  |  2020  |  Clinical Nutrition

According to the World Health Organisation, 70% of all deaths globally can be attributed to chronic inflammatory diseases such as ..

Synchrotron-Fourier transform infrared maps of ovalbumin-induced murine chronic allergic airways disease: Correlation with conventional histology.

Nadia Mazarakis, Jitraporn Vongsvivut, Keith R Bambery, Kenneth J Snibson, Simon G Royce, Tom C Karagiannis

Journal article  |  2017  |  Hellenic journal of nuclear medicine

Asthma is a chronic respiratory disease characterised by airway inflammation, remodeling and hyperresponsiveness. The ability to r..

Systems approach to the pharmacological actions of HDAC inhibitors reveals EP300 activities and convergent mechanisms of regulation in diabetes

Haloom Rafehi, Antony Kaspi, Mark Ziemann, Jun Okabe, Tom C Karagiannis, Assam El-Osta

Journal article  |  2017  |  Epigenetics

Pharmacological Histone Deacetylation Distinguishes Transcriptional Regulators

Haloom Rafehi, Tom C Karagiannis, Assam El-Osta

Conference Proceedings  |  2017  |  Current Topics in Medicinal Chemistry

Strand breakage by decay of DNA-bound I-124 provides a basis for combined PET imaging and Auger endoradiotherapy

Pavel Lobachevsky, George R Clark, Patrycja D Pytel, Brenda Leung, Colin Skene, Laura Andrau, Jonathan M White, Tom Karagiannis, Carleen Cullinane, Boon Q Lee, Andrew Stuchbery, Tibor Kibedi, Rodney J Hicks, Roger F Martin

Journal article  |  2016  |  International Journal of Radiation Biology

Qualitative and Quantitative Analysis of Histone Deacetylases in Kidney Tissue Sections

Katherine Ververis, Selly Marzully, Chrishan S Samuel, Tim D Hewitson, Tom C Karagiannis

Book Chapter  |  2016  |  Methods in Molecular Biology

Exploration of mechanisms in nutriepigenomics: Identification of chromatin-modifying compounds from Olea Europaea

Natalie P Bonvino, Nancy B Ray, Vi T Luu, Julia Liang, Andrew Hung, Tom C Karagiannis

Journal article  |  2015  |  Hellenic journal of nuclear medicine

The Implication of Cancer Progenitor Cells and the Role of Epigenetics in the Development of Novel Therapeutic Strategies for Chronic Myeloid Leukemia

Stephanie M Tortorella, Andrew Hung, Tom C Karagiannis

Journal article  |  2015  |  Antioxidants & Redox Signaling