Mo Haskali

Effective Preparation of [F-18]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor

Mohammad B Haskali, Peter D Roselt, Terence J O'Brien, Craig A Hutton, Idrish Ali, Lucy Vivash, Bianca Jupp

Journal article  |  2022  |  MOLECULES

(1) Background: [18F]Flumazenil 1 ([18F]FMZ) is an established positron emission tomography (PET) radiotracer for the imaging of t..

Investigation of Fluorine-18 Labelled Peptides for Binding to Cholecystokinin-2 Receptors with High Affinity

Naeem-Ul-Haq Khan, Alicia Corlett, Craig A Hutton, Mohammad B Haskali

Journal article  |  2022  |  INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS

Many cancers of neuroendocrine origin overexpress cholecystokinin-2 receptors (CCK-2R) including medullary thyroid cancer, small c..

Radiolabelled Peptides: Optimal Candidates for Theranostic Application in Oncology

Andrew J Hall, Mohammad B Haskali

Journal article  |  2021  |  AUSTRALIAN JOURNAL OF CHEMISTRY

Theranostics are drugs suitable for use in both diagnostic and therapeutic applications, and have played an important role in the ..

The Protein Landscape of Mucinous Ovarian Cancer: Towards a Theranostic

Arkan Youssef, Mohammad B Haskali, Kylie L Gorringe

Journal article  |  2021  |  CANCERS

MOC is a rare histotype of epithelial ovarian cancer, and current management options are inadequate for the treatment of late stag..

Development of [F-18]MIPS15692, a radiotracer with in vitro proof-of-concept for the imaging of MER tyrosine kinase (MERTK) in neuroinflammatory disease

Siu Wai Wong, Lucy Vivash, Ramesh Mudududdla, Nghi Nguyen, Stefan J Hermans, David M Shackleford, Judith Field, Lian Xue, Andrea Aprico, Nancy C Hancock, Mohammad Haskali, Michael A Stashko, Stephen Frye, Xiaodong Wang, Michele D Binder, Uwe Ackermann, Michael W Parker, Trevor J Kilpatrick, Jonathan B Baell

Journal article  |  2021  |  EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

MER tyrosine kinase (MERTK) upregulation is associated with M2 polarization of microglia, which plays a vital role in neuroregener..

Foldamers afford improved theranostics targeting cholecystokinin-2 receptor positive cancers

Alicia Corlett, Marc-Antoine Sani, Jessica Van Zuylekom, Craig Hutton, Mohammad Haskali

Conference Proceedings  |  2021  |  NUCLEAR MEDICINE AND BIOLOGY

Structure-activity relationship study of peptide Gastramide-01 (GA-01), a potent binder of cholecystokinin-2 (CCK-2) receptor and theranostic candidate

Marwa Rahimi, Alicia Corlett, Jessica Van Zuylekom, Benjamin Blyth, Philip Thompson, Mohammad Haskali

Conference Proceedings  |  2021  |  NUCLEAR MEDICINE AND BIOLOGY

Next generation therapeutic radiopharmaceuticals targeting cholecystokinin-2 receptor positive cancers

Alicia Corlett, Jessica Van Zuylekom, Benjamin Blyth, Mohammad Haskali

Conference Proceedings  |  2021  |  NUCLEAR MEDICINE AND BIOLOGY

F-18 labelled albumin binding synthons enabling PET imaging and enhanced target accumulation of biomolecules

Andrew Hall, Alicia Corlett, Mohammad Haskali

Conference Proceedings  |  2021  |  NUCLEAR MEDICINE AND BIOLOGY

A New Turn in Peptide-Based Imaging Agents: Foldamers Afford Improved Theranostics Targeting Cholecystokinin-2 Receptor-Positive Cancer

Alicia Corlett, Marc-Antoine Sani, Jessica Van Zuylekom, Ching-Seng Ang, Elisabeth von Guggenberg, Carleen Cullinane, Benjamin Blyth, Rodney J Hicks, Peter D Roselt, Philip E Thompson, Craig A Hutton, Mohammad B Haskali

Journal article  |  2021  |  JOURNAL OF MEDICINAL CHEMISTRY

Proteins adopt unique folded secondary and tertiary structures that are responsible for their remarkable biological properties. Th..