Roxanne Hastie

Aspirin use during pregnancy and the risk of bleeding complications: a Swedish population-based cohort study

Roxanne Hastie, Stephen Tong, Anna-Karin Wikstrom, Anna Sandstrom, Susanne Hesselman, Lina Bergman

Journal article  |  2021  |  American Journal of Obstetrics and Gynecology

BACKGROUND: Aspirin is offered to pregnant women to prevent preeclampsia, a severe obstetrical complication. Large studies of nonp..

Pravastatin, proton-pump inhibitors, metformin, micronutrients, and biologics: new horizons for the prevention or treatment of preeclampsia.

Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Roxanne Hastie, Fiona Brownfoot, Catherine Cluver, Natalie Hannan

Journal article  |  2020  |  American Journal of Obstetrics and Gynecology

There has been increasing research momentum to identify new therapeutic agents for the prevention or treatment of preeclampsia, dr..

Duration of labor among women with hypertensive disorders of pregnancy; A Swedish register cohort study.

Roxanne Hastie, Lina Bergman, Tansim Akhter, Anna Sandström, Anna-Karin Wikström, Susanne Hesselman

Journal article  |  2020  |  European Journal of Obstetrics & Gynecology and Reproductive Biology

OBJECTIVE: Preeclampsia is a severe obstetric complication affecting 2-8% of pregnancies. There is a common belief that women with..

Combining metformin and sulfasalazine additively reduces the secretion of antiangiogenic factors from the placenta: Implications for the treatment of preeclampsia

Fiona C Brownfoot, Roxanne Hastie, Natalie J Hannan, Ping Cannon, Tuong Nguyen, Laura Tuohey, Cathy Cluver, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2020  |  Placenta

INTRODUCTION: The antiangiogenic factors soluble fms-like tyrosine kinase-1 (sFlt-1) and soluble endoglin (sENG) are elevated in p..

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Tu'uhevaha J Kaitu'u-Lino, Teresa M MacDonald, Ping Cannon, Nguyen Tuong-Vi, Richard J Hiscock, Nick Haan, Jenny E Myers, Roxanne Hastie, Kirsten M Dane, Anna L Middleton, Intissar Bittar, Amanda N Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P Walker, Stephen Tong

Journal article  |  2020  |  Nature Communications

Placental insufficiency can cause fetal growth restriction and stillbirth. There are no reliable screening tests for placental ins..

Accuracy of clinical suspicion of growth restriction at term despite a normal growth ultrasound: A retrospective cohort study

Brittany Green, Lisa Hui, Roxanne Hastie, Stephen Tong, Fiona C Brownfoot

Journal article  |  2020  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

Acupuncture in pregnancy; primum non nocere

R Hastie, BW Mol, S Tong

Journal article  |  2020  |  BJOG An International Journal of Obstetrics & Gynaecology

It is thought that around 10% of pregnant women turn to acupuncture to alleviate troublesome pregnancy ailments: vomiting, pelvic,..

Combination methotrexate and gefitinib: A potential medical treatment for inoperable nontubal ectopic pregnancy

Stella Italiano, Stephen Tong, Emma Readman, Meredith Tassone, Roxanne Hastie, Natasha Pritchard

Conference Proceedings  |  2019  |  Journal of Obstetrics and Gynaecology Research

The incidence of hypertensive disorders of pregnancy following sperm donation in IVF: an Australian state-wide retrospective cohort study

Amber L Kennedy, Cathryn J Stern, Stephen Tong, Roxanne Hastie, Franca Agresta, Susan P Walker, Fiona C Brownfoot, Vivien MacLachlan, Beverley J Vollenhoven, Anthea C Lindquist

Journal article  |  2019  |  Human Reproduction

STUDY QUESTION: Does IVF using donor sperm increase the risk of hypertensive disorders of pregnancy and fetal growth restriction (..

Sulfasalazine decreases soluble fms-like tyrosine kinase-1 secretion potentially via inhibition of upstream placental epidermal growth factor receptor signalling

Roxanne Hastie, Fiona C Brownfoot, Ping Cannon, Nguyen Vi, Laura Tuohey, Natalie J Hannan, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2019  |  Placenta

OBJECTIVES: Preeclampsia is a hypertensive disorder of pregnancy with no available medical treatment. We recently reported sulfasa..