Karen Day

Evolutionary analyses of the major variant surface antigen-encoding genes reveal population structure of Plasmodium falciparum within and between continents

Gerry Tonkin-Hill, Shazia Ruybal-Pesantez, Kathryn E Tiedje, Virginie Rougeron, Michael F Duffy, Sedigheh Zakeri, Tepanata Pumpaibool, Pongchai Harnyuttanakorn, OraLee H Branch, Lastenia Ruiz-Mesia, Thomas S Rask, Franck Prugnolle, Anthony T Papenfuss, Yao-ban Chan, Karen P Day

Journal article  |  2021  |  PLOS Genetics

Malaria remains a major public health problem in many countries. Unlike influenza and HIV, where diversity in immunodominant surfa..

Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences

Jingyi Tang, Scott A Chisholm, Lee M Yeoh, Paul R Gilson, Anthony T Papenfuss, Karen P Day, Michaela Petter, Michael F Duffy

Journal article  |  2020  |  Epigenetics and Chromatin

BACKGROUND: The malaria parasite Plasmodium falciparum has an unusually euchromatic genome with poorly conserved positioning of nu..

Evolution of Antimalarial Drug Resistance Markers in the Reservoir of Plasmodium falciparum Infections in the Upper East Region of Ghana

Charles A Narh, Anita Ghansah, Michael F Duffy, Shazia Ruybal-Pesantez, Christiana O Onwona, Abraham R Oduro, Kwadwo A Koram, Karen P Day, Kathryn E Tiedje

Journal article  |  2020  |  The Journal of Infectious Diseases

BACKGROUND: The majority of Plasmodium falciparum infections, constituting the reservoir in all ages, are asymptomatic in high-tra..

Competition for hosts modulates vast antigenic diversity to generate persistent strain structure in Plasmodium falciparum

Shai Pilosof, Qixin He, Kathryn E Tiedje, Shazia Ruybal-Pesantez, Karen P Day, Mercedes Pascual

Journal article  |  2019  |  PLoS Biology

GLOBAL STRUCTURE OF THE VAR GENES ENCODING THE MAJOR VARIANT SURFACE ANTIGEN OF PLASMODIUM FALCIPARUM

Gerry Tonkin-Hill, Shazia Ruybal-Pesantez, Kathryn E Tiedje, Virginie Rougeron, Sedigheh Zakeri, Tepanata Pumpaibool, Pingchai Harnyuttanakorn, OraLee H Branch, Lastenia Ruiz-Mesia, Michael F Duffy, Thomas S Rask, Franck Prugnolle, Yao-Ban Yao-Ban Chan, Anthony T Papenfuss, Karen P Day

Conference Proceedings  |  2019  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

EVOLUTION OF PLASMODIUM FALCIPARUM AFTER AN OUTBREAK FACILITATES LOW ENDEMICITY MALARIA TRANSMISSION IN ECUADOR

Shazia Ruybal-Pesantez, Fabian E Saenz, Claudia A Vera-Arias, Kathryn E Tiedje, Karen P Day

Conference Proceedings  |  2019  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Ghosts in the Machine: Identifying the Digital Health Information Workforce.

Kathleen Gray, Cecily Gilbert, Kerryn Butler-Henderson, Karen Day, Simone Pritchard

Journal article  |  2019  |  Stud Health Technol Inform

In descriptions of digital health the role of human agency and the work of managing and governing health information and communica..

Identifying functional groups among the diverse, recombining antigenic var genes of the malaria parasite Plasmodium falciparum from a local community in Ghana

Mary M Rorick, Edward B Baskerville, Thomas S Rask, Karen P Day, Mercedes Pascual

Journal article  |  2018  |  PLOS Computational Biology

Networks of genetic similarity reveal non-neutral processes shape strain structure in Plasmodium falciparum

Qixin He, Shai Pilosof, Kathryn E Tiedje, Shazia Ruybal-Pesantez, Yael Artzy-Randrup, Edward B Baskerville, Karen P Day, Mercedes Pascual

Journal article  |  2018  |  Nature Communications

Signatures of competition and strain structure within the major blood-stage antigen of Plasmodium falciparum in a local community in Ghana

Mary M Rorick, Yael Artzy-Randrup, Shazia Ruybal-Pesantez, Kathryn E Tiedje, Thomas S Rask, Abraham Oduro, Anita Ghansah, Kwadwo Koram, Karen P Day, Mercedes Pascual

Journal article  |  2018  |  Ecology and Evolution