Farzan Akbaridoust

A microfluidic method to investigate platelet mechanotransduction under extensional strain.

Nurul A Zainal Abidin, Mariia Timofeeva, Crispin Szydzik, Farzan Akbaridoust, Chitrarth Lav, Ivan Marusic, Arnan Mitchell, Justin R Hamilton, Andrew SH Ooi, Warwick S Nesbitt

Journal article  |  2023  |  Res Pract Thromb Haemost

BACKGROUND: Blood platelets have evolved a complex mechanotransduction machinery to rapidly respond to hemodynamic conditions. A v..

Ensembled Deep Learning for the Classification of Human Sperm Head Morphology

Lindsay Spencer, Jared Fernando, Farzan Akbaridoust, Klaus Ackermann, Reza Nosrati

Journal article  |  2022  |  Advanced Intelligent Systems

An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients

Nurul A Zainal Abidin, Eric KW Poon, Crispin Szydzik, Mariia Timofeeva, Farzan Akbaridoust, Rose J Brazilek, Francisco J Tovar Lopez, Xiao Ma, Chitrarth Lav, Ivan Marusic, Philip E Thompson, Arnan Mitchell, Andrew SH Ooi, Justin R Hamilton, Warwick S Nesbitt

Journal article  |  2022  |  BMC BIOLOGY

BACKGROUND: Supraphysiological hemodynamics are a recognized driver of platelet activation and thrombosis at high-grade stenosis a..

Are surgical masks manufactured from sterilisation wrap safe?

Sam E Grigg, Andrea Zampiron, Farzan Akbaridoust, Dileep Chandran, Natasha E Holmes, Paul DR Johnson, Ivan Marusic, Daryl Jones

Journal article  |  2021  |  INFECTION DISEASE & HEALTH

BACKGROUND: Due to regional shortages some health services have proposed using surgical masks manufactured from sterilisation wrap..

RESOLVING SPERM MOTILITY NEAR PILLARS USING μPIV

MS Abdul Halim, F Akbaridoust, R Nosrati

Conference Proceedings  |  2021  |  MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Experimental fluid dynamics characterization of a novel micropump-mixer

F Akbaridoust, CM de Silva, C Szydzik, A Mitchell, I Marusic, WS Nesbitt

Journal article  |  2020  |  Biomicrofluidics

The application of lab-on-a-chip systems to biomedical engineering and medical biology is rapidly growing. Reciprocating micropump..

Paper-Based Acoustofluidics for Separating Particles and Cells

Jason Zhou, Ruhollah Habibi, Farzan Akbaridoust, Adrian Neild, Reza Nosrati

Journal article  |  2020  |  Analytical Chemistry

Paper is emerging as a versatile platform for automated fluid handling with a broad range of applications in medical diagnostics a..

Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood

Crispin Szydzik, Rose J Brazilek, Farzan Akbaridoust, Charitha de Silva, Mitchell Moon, Ivan Marusic, Andrew SH Ooi, Harshal H Nandurkar, Justin R Hamilton, Arnan Mitchell, Warwick S Nesbitt

Journal article  |  2019  |  Analytical Chemistry

There is a need for scalable automated lab-on-chip systems incorporating precise hemodynamic control that can be applied to high-c..

Towards An Active Micropump-mixer for Rapid Anti-platelet Drug Screening in Whole Blood

Crispin Szydzik, Rose J Brazilek, Farzan Akbaridoust, Charitha de Silva, Mitchell Moon, Ivan Marusic, Harshal H Nandurkar, Justin R Hamilton, Arnan Mitchell, Warwick S Nesbitt

Conference Proceedings  |  2019  |  SPIE MICRO + NANO MATERIALS, DEVICES, AND APPLICATIONS 2019

This work reports on development and characterization of an on-chip microfluidic handling system for application in preclinical an..

Examining flow dynamics of platelet function in micro-contractions using micro-PIV

Farzan Akbaridoust, Charitha de Silva, Rose Brazilek, Xiao Chen, Francisco Tovar-Lopez, Eric King Wai Poon, Andrew Ooi, Arnan Mitchell, Warwick Nesbitt, Harshal Nandurkar, Ivan Marusic

Conference Proceedings  |  2018  |  Proceedings of the 21st Australasian Fluid Mechanics Conference

This study examines the flow field in the near-vicinity of microcontraction-expansion geometries in microfluidic devices designed ..