Hong Nguyen

EGFRvIII Promotes Cell Survival during Endoplasmic Reticulum Stress through a Reticulocalbin 1-Dependent Mechanism

Juliana Gomez, Zammam Areeb, Sarah F Stuart, Hong PT Nguyen, Lucia Paradiso, Ahmad Zulkifli, Sonakshi Madan, Vijay Rajagopal, Magdalene K Montgomery, Hui K Gan, Andrew M Scott, Jordan Jones, Andrew H Kaye, Andrew P Morokoff, Rodney B Luwor

Journal article  |  2021  |  CANCERS

Reticulocalbin 1 (RCN1) is an endoplasmic reticulum (ER)-residing protein, involved in promoting cell survival during pathophysiol..

Circulating Biomarkers for Glioma: A Review

Jordan Jones, Hong Nguyen, Katharine Drummond, Andrew Morokoff

Journal article  |  2021  |  NEUROSURGERY

Accurate circulating biomarkers have potential clinical applications in population screening, tumor subclassification, monitoring ..

Reduced EGFR and increased miR-221 is associated with increased resistance to temozolomide and radiotherapy in glioblastoma

Zammam Areeb, Sarah F Stuart, Alice J West, Juliana Gomez, Hong PT Nguyen, Lucia Paradiso, Ahmad Zulkifli, Jordan Jones, Andrew H Kaye, Andrew P Morokoff, Rodney B Luwor

Journal article  |  2020  |  SCIENTIFIC REPORTS

Despite aggressive treatment with temozolomide and radiotherapy and extensive research into alternative therapies there has been l..

Serum microRNA is a biomarker for post-operative monitoring in glioma

Andrew Morokoff, Jordan Jones, Hong Nguyen, Chenkai Ma, Arian Lasocki, Frank Gaillard, Iwan Bennett, Rod Luwor, Stanley Stylli, Lucia Paradiso, Rachel Koldej, Iddo Paldor, Ramyar Molania, Terence P Speed, Andrew Webb, Guiseppe Infusini, Jason Li, Charles Malpas, Tomas Kalincik, Katharine Drummond, et al.

Journal article  |  2020  |  JOURNAL OF NEURO-ONCOLOGY

PURPOSE: A circulating biomarker has potential to provide more accurate information for glioma progression post treatment, however..

Human Endometrial Extracellular Vesicles Functionally Prepare Human Trophectoderm Model for Implantation: Understanding Bidirectional Maternal-Embryo Communication

Jemma Evans, Alin Rai, Hong PT Nguyen, Qi Hui Poh, Kirstin Elglass, Richard J Simpson, Lois A Salamonsen, David W Greening

Journal article  |  2019  |  PROTEOMICS

Embryo implantation into maternal endometrium is critical for initiation and establishment of pregnancy, requiring developmental s..

Targeting Glioma Stem Cells by Functional Inhibition of Dynamin 2: A Novel Treatment Strategy for Glioblastoma

Rodney Luwor, Andrew P Morokoff, Stephanie Amiridis, Giovanna D'Abaco, Lucia Paradiso, Stanley S Stylli, Hong PT Nguyen, Mark Tarleton, Kelly A Young, Terence J O'Brien, Phillip J Robinson, Megan Chircop, Adam McCluskey, Nigel C Jones

Journal article  |  2019  |  CANCER INVESTIGATION

Glioma stem cells (GSCs) play major roles in drug resistance, tumour maintenance and recurrence of glioblastoma. We investigated i..

Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs

Clarissa A Whitehead, Hong PT Nguyen, Andrew P Morokoff, Rodney B Luwor, Lucia Paradiso, Andrew H Kaye, Theo Mantamadiotis, Stanley S Stylli

Journal article  |  2018  |  TRANSLATIONAL ONCOLOGY

The most common primary central nervous system tumor in adults is the glioblastoma multiforme (GBM). The highly invasive nature of..

The role of interleukin-6-STAT3 signalling in glioblastoma

Alice J West, Vanessa Tsui, Stanley S Stylli, Hong PT Nguyen, Andrew P Morokoff, Andrew H Kaye, Rodney B Luwor

Journal article  |  2018  |  ONCOLOGY LETTERS

Glioblastoma is the most common type of malignant brain tumor among adults and is currently a non-curable disease due primarily to..

A comprehensive meta-analysis of circulation miRNAs in glioma as potential diagnostic biomarker

Chenkai Ma, Hong PT Nguyen, Rodney B Luwor, Stanley S Stylli, Andrew Gogos, Lucia Paradiso, Andrew H Kaye, Andrew P Morokoff

Journal article  |  2018  |  PLOS ONE

Glioma is the most common malignant intracranial tumour. Recently, several publications have suggested that miRNAs can be used as ..

Amnion Epithelial Cell-Derived Exosomes Restrict Lung Injury and Enhance Endogenous Lung Repair

Jean L Tan, Sin N Lau, Bryan Leaw, Hong PT Nguyen, Lois A Salamonsen, Mohamed I Saad, Siow T Chan, Dandan Zhu, Mirja Krause, Carla Kim, William Sievert, Euan M Wallace, Rebecca Lim

Journal article  |  2018  |  STEM CELLS TRANSLATIONAL MEDICINE

Idiopathic pulmonary fibrosis (IPF) is characterized by chronic inflammation, severe scarring, and stem cell senescence. Stem cell..