Michael Pan

Network Thermodynamical Modeling of Bioelectrical Systems: A Bond Graph Approach

Peter J Gawthrop, Michael Pan

Journal article  |  2021  |  Bioelectricity

A thermodynamic framework for modelling membrane transporters

Michael Pan, Peter J Gawthrop, Kenneth Tran, Joseph Cursons, Edmund J Crampin

Journal article  |  2019  |  Journal of Theoretical Biology

Membrane transporters contribute to the regulation of the internal environment of cells by translocating substrates across cell me..

A bond graph approach to integrative biophysical modelling

Michael Pan

Thesis / Dissertation  |  2019

A major goal of systems biology is to develop comprehensive, multi-scale mathematical models of physiological systems that integra..

Bond graph modelling of the cardiac action potential: implications for drift and non-unique steady states

Michael Pan, Peter J Gawthrop, Kenneth Tran, Joseph Cursons, Edmund J Crampin

Journal article  |  2018  |  Proceedings of the Royal Society A

When push comes to shove: Exclusion processes with nonlocal consequences

Axel A Almet, Michael Pan, Barry D Hughes, Kerry A Landman

Journal article  |  2015  |  PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS

Hierarchical semantic composition of biosimulation models using bond graphs

Niloofar Shahidi, Michael Pan, Soroush Safaei, Kenneth Tran, Edmund J Crampin, David P Nickerson

Journal article

AbstractSimulating complex biological and physiological systems and predicting their behaviours under different conditions remains..

Modular Dynamic Biomolecular Modelling: The Unification of Stoichiometry, Thermodynamics, Kinetics and Data

Peter J Gawthrop, Michael Pan, Edmund J Crampin

Journal article

AbstractRenewed interest in dynamic simulation models of biomolecular systems has arisen from advances in genome-wide measurement ..

Modelling cardiomyocyte energetics

Edmund J Crampin, Michael Pan, Kenneth Tran, Shourya Ghosh, Vijay Rajagopal

Book Chapter

The cardiac Na /K ATPase: An updated, thermodynamically consistent model

Michael Pan, Peter J Gawthrop, Joseph Cursons, Kenneth Tran, Edmund J Crampin

Journal article

The Na+/K+ATPase is an essential component of cardiac electrophysiology, maintaining physiological Na+ and K+ concentrations over ..

The cardiac Na /K ATPase: An updated, thermodynamically consistent model

Michael Pan, Peter J Gawthrop, Joseph Cursons, Kenneth Tran, Edmund J Crampin

Journal article

The Na+/K+ATPase is an essential component of cardiac electrophysiology, maintaining physiological Na+ and K+ concentrations over ..