Dallas English

Factors explaining socio-economic inequalities in survival from colon cancer: a causal mediation analysis.

Nina Afshar, S Ghazaleh Dashti, Luc Te Marvelde, Tony Blakely, Andrew Haydon, Victoria M White, Jon D Emery, Rebecca J Bergin, Kathryn Whitfield, Robert Js Thomas, Graham G Giles, Roger L Milne, Dallas R English

Journal article  |  2021  |  Cancer Epidemiol Biomarkers Prev

BACKGROUND: Socio-economic inequalities in colon cancer survival exist in high-income countries, but the reasons are unclear. We a..

Genetic architectures of proximal and distal colorectal cancer are partly distinct

Jeroen R Huyghe, Tabitha A Harrison, Stephanie A Bien, Heather Hampel, Jane C Figueiredo, Stephanie L Schmit, David Conti, Sai Chen, Conghui Qu, Yi Lin, Richard Barfield, John A Baron, Amanda J Cross, Brenda Diergaarde, David Duggan, Sophia Harlid, Liher Imaz, Hyun Min Kang, David M Levine, Vittorio Perduca, et al.

Journal article  |  2021  |  GUT

OBJECTIVE: An understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision preventi..

Association of markers of inflammation, the kynurenine pathway and B vitamins with age and mortality, and a signature of inflammaging.

Pierre-Antoine Dugué, Allison M Hodge, Arve Ulvik, Per M Ueland, Øivind Midttun, Sabina Rinaldi, Robert J Macinnis, Sherly X Li, Klaus Meyer, Anne-Sophie Navionis, Leon Flicker, Gianluca Severi, Dallas R English, Paolo Vineis, Grethe S Tell, Melissa C Southey, Roger L Milne, Graham G Giles

Journal article  |  2021  |  J Gerontol A Biol Sci Med Sci

BACKGROUND: Inflammation is a key feature of aging. We aimed to i) investigate the association of 34 blood markers potentially inv..

Prospective Evaluation of the Addition of Polygenic Risk Scores to Breast Cancer Risk Models

Sherly X Li, Roger L Milne, Tu Nguyen-Dumont, Xiaochuan Wang, Dallas R English, Graham G Giles, Melissa C Southey, Antonis C Antoniou, Andrew Lee, Shuai Li, Ingrid Winship, John L Hopper, Mary Beth Terry, Robert J MacInnis

Journal article  |  2021  |  JNCI CANCER SPECTRUM

Background: The Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm and the International Breast Can..

DNA Methylation Signatures and the Contribution of Age-Associated Methylomic Drift to Carcinogenesis in Early-Onset Colorectal Cancer

Jihoon E Joo, Mark Clendenning, Ee Ming Wong, Christophe Rosty, Khalid Mahmood, Peter Georgeson, Ingrid M Winship, Susan G Preston, Aung Ko Win, Pierre-Antoine Dugue, Harindra Jayasekara, Dallas English, Finlay A Macrae, John L Hopper, Mark A Jenkins, Roger L Milne, Graham G Giles, Melissa C Southey, Daniel D Buchanan

Journal article  |  2021  |  CANCERS

We investigated aberrant DNA methylation (DNAm) changes and the contribution of ageing-associated methylomic drift and age acceler..

Prediagnosis alcohol intake and metachronous cancer risk in cancer survivors: A prospective cohort study

Harindra Jayasekara, Allison M Hodge, Andrew Haydon, Robin Room, John L Hopper, Dallas R English, Stephanie A Smith-Warner, Graham G Giles, Roger L Milne, Robert J MacInnis

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF CANCER

Alcohol consumption is a known cause of cancer, but its role in the etiology of second primary (metachronous) cancer is uncertain...

Predicting deseasonalised serum 25 hydroxy vitamin D concentrations in the D-Health Trial: An analysis using boosted regression trees.

Mary Waterhouse, Catherine Baxter, Briony Duarte Romero, Donald SA McLeod, Dallas R English, Bruce K Armstrong, Michael W Clarke, Peter R Ebeling, Gunter Hartel, Michael G Kimlin, Rachel L O'Connell, Hai Pham, Rachael M Rodney Harris, Jolieke C van der Pols, Alison J Venn, Penelope M Webb, David C Whiteman, Rachel E Neale

Journal article  |  2021  |  Contemp Clin Trials

BACKGROUND: The D-Health Trial aims to determine whether monthly high-dose vitamin D supplementation can reduce the mortality rate..

Smoking, alcohol consumption, body fatness, and risk of myelodysplastic syndromes: A prospective study.

Harindra Jayasekara, Robert J MacInnis, Surender Juneja, Julie K Bassett, Fiona Bruinsma, Brigid M Lynch, Allison M Hodge, John L Hopper, Dallas R English, Graham G Giles, Roger L Milne

Journal article  |  2021  |  Leuk Res

ASSOCIATION BETWEEN CIRCULATING 25-HYDROXYVITAMIN D CONCENTRATIONS AND HIP REPLACEMENT FOR OSTEOARTHRITIS: RESULTS FROM A PROSPECTIVE COHORT STUDY

S Hussain, Y Wang, AK Heath, GG Giles, DR English, DW Eyles, EJ Williamson, SE Graves, AE Wluka, FM Cicuttini

Journal article  |  2021  |  OSTEOARTHRITIS AND CARTILAGE

Epigenetic Drift Association with Cancer Risk and Survival, and Modification by Sex

Chenglong Yu, Ee Ming Wong, Jihoon Eric Joo, Allison M Hodge, Enes Makalic, Daniel Schmidt, Daniel D Buchanan, Gianluca Severi, John L Hopper, Dallas R English, Graham G Giles, Melissa C Southey, Pierre-Antoine Dugue

Journal article  |  2021  |  CANCERS

To investigate age- and sex-specific DNA methylation alterations related to cancer risk and survival, we used matched case-control..