Sayali Shah

Synthesis of C-Mannosylated Glycopeptides Enabled by Ni-Catalyzed Photoreductive Cross-Coupling Reactions

Runyu Mao, Shiyi Xi, Sayali Shah, Michael J Roy, Alan John, James P Lingford, Gerd Gade, Nichollas E Scott, Ethan D Goddard-Borger

Journal article  |  2021  |  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The biological functions of tryptophan C-mannosylation are poorly understood, in part, due to a dearth of methods for preparing pu..

Yeast- and antibody-based tools for studying tryptophan C-mannosylation

Alan John, Michael A Jarva, Sayali Shah, Runyu Mao, Stephane Chappaz, Richard W Birkinshaw, Peter E Czabotar, Alvin W Lo, Nichollas E Scott, Ethan D Goddard-Borger

Journal article  |  2021  |  NATURE CHEMICAL BIOLOGY

Tryptophan C-mannosylation is an unusual co-translational protein modification performed by metazoans and apicomplexan protists. T..

alpha-Glucuronosyl and alpha-glucosyl diacylglycerides, natural killer T cell-activating lipids from bacteria and fungi

Satvika Burugupalli, Catarina F Almeida, Dylan GM Smith, Sayali Shah, Onisha Patel, Jamie Rossjohn, Adam P Uldrich, Dale I Godfrey, Spencer J Williams

Journal article  |  2020  |  CHEMICAL SCIENCE

Natural killer T cells express T cell receptors (TCRs) that recognize glycolipid antigens in association with the antigen-presenti..

Synthesis of carbohydrate lipids and their roles in innate immunity

Phillip van der Peet, Nguyen Tram, Satvika Burugupalli, Sayali Shah, Spencer Williams

Conference Proceedings  |  2019  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation

Alan Cartmell, Jose Munoz-Munoz, Jonathon A Briggs, Didier A Ndeh, Elisabeth C Lowe, Arnaud Basle, Nicolas Terrapon, Katherine Stott, Tiaan Heunis, Joe Gray, Li Yu, Paul Dupree, Pearl Z Fernandes, Sayali Shah, Spencer J Williams, Aurore Labourel, Matthias Trost, Bernard Henrissat, Harryj Gilbert

Journal article  |  2018  |  NATURE MICROBIOLOGY

Glycans are major nutrients for the human gut microbiota (HGM). Arabinogalactan proteins (AGPs) comprise a heterogenous group of p..

Investigation of benzoyloximes as benzoylating reagents: benzoyl-Oxyma as a selective benzoylating reagent

Satvika Burugupalli, Sayali Shah, Phillip L van der Peet, Seep Arora, Jonathan M White, Spencer J Williams

Journal article  |  2016  |  ORGANIC & BIOMOLECULAR CHEMISTRY

Hydroxybenzotriazole (HOBt) and HOBt-derived reagents have been classified as Class I explosives, with restrictions on their trans..

Total synthesis of a cyclopropane-fatty acid alpha-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle

Sayali Shah, Masahiro Nagata, Sho Yamasaki, Spencer J Williams

Journal article  |  2016  |  CHEMICAL COMMUNICATIONS

We report a concise synthesis of glycolipid GL1 from Lactobacillus plantarum commencing from methyl α-d-glucopyroside. A Jacobsen ..

Lipid structure influences the ability of glucose monocorynomycolate to signal through Mincle

Phillip L van der Peet, Masahiro Nagata, Sayali Shah, Jonathan M White, Sho Yamasaki, Spencer J Williams

Journal article  |  2016  |  ORGANIC & BIOMOLECULAR CHEMISTRY

Mincle (macrophage-inducible C-type lectin) is a C-type lectin receptor that provides the capacity for immune sensing of a range o..

Total syntheses of cis-cyclopropane fatty acids: dihydromalvalic acid, dihydrosterculic acid, lactobacillic acid, and 9,10-methylenehexadecanoic acid

Sayali Shah, Jonathan M White, Spencer J Williams

Journal article  |  2014  |  ORGANIC & BIOMOLECULAR CHEMISTRY

cis-Cyclopropane fatty acids (cis-CFAs) are widespread constituents of the seed oils of subtropical plants, membrane components of..