Kim Mulholland

Does respiratory syncytial virus lower respiratory illness in early life cause recurrent wheeze of early childhood and asthma? Critical review of the evidence and guidance for future studies from a World Health Organization-sponsored meeting.

Amanda J Driscoll, S Hasan Arshad, Louis Bont, Steven M Brunwasser, Thomas Cherian, Janet A Englund, Deshayne B Fell, Laura L Hammitt, Tina V Hartert, Bruce L Innis, Ruth A Karron, Gayle E Langley, E Kim Mulholland, Patrick K Munywoki, Harish Nair, Justin R Ortiz, David A Savitz, Nienke M Scheltema, Eric AF Simões, Peter G Smith, et al.

Journal article  |  2020  |  Vaccine

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection (LRTI) and hospitalization in infants an..

State-of-the-art in the pneumococcal field: Proceedings of the 11(th) International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD-11)

Brenda Anna Kwambana-Adams, E Kim Mulholland, Catherine Satzke, Heidi Smith-Vaughan, Angela Brueggemann, Cynthia Whitney, Lea-Ann Kirkham, Raquel Sa-Leao, Jorge Vidal, Hamish Graham, David Murdoch, Glaucia Paranhos-Baccala, David Goldblatt, William S Pomat, Emma Best, Peter McIntyre, Jodie McVernon, Daniel Weinberger, Eileen Dunne, J Anthony Scott, et al.

Journal article  |  2020  |  Pneumonia

The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) is the premier global scientific symposium dedicated ..

Birth outcomes in Aboriginal mother-infant pairs from the Northern Territory, Australia, who received 23-valent polysaccharide pneumococcal vaccination during pregnancy, 2006-2011: The PneuMum randomised controlled trial.

Lisa McHugh, Michael Binks, Robert S Ware, Tom Snelling, Sandra Nelson, Jane Nelson, Melissa Dunbar, E Kim Mulholland, Ross M Andrews

Journal article  |  2020  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

BACKGROUND: Pregnant women and infants <6 months old have a high baseline risk for pneumococcal disease compared to the general po..

Associations between ethnicity, social contact, and pneumococcal carriage three years post-PCV10 in Fiji

Eleanor FG Neal, Stefan Flasche, Cattram D Nguyen, F Tupou Ratu, Eileen M Dunne, Lanieta Koyamaibole, Rita Reyburn, Eric Rafai, Mike Kama, Belinda D Ortika, Laura K Boelsen, Joseph Kado, Lisi Tikoduadua, Rachel Devi, Evelyn Tuivaga, Catherine Satzke, E Kim Mulholland, W John Edmunds, Fiona M Russell

Journal article  |  2020  |  Vaccine

BACKGROUND: Pneumococcal carriage is a prerequisite for pneumococcal disease. Little is known about whether social contact frequen..

Factors associated with pneumococcal carriage and density in children and adults in Fiji, using four cross-sectional surveys.

Eleanor FG Neal, Cattram D Nguyen, Felista T Ratu, Eileen M Dunne, Mike Kama, Belinda D Ortika, Laura K Boelsen, Joseph Kado, Lisi Tikoduadua, Rachel Devi, Evelyn Tuivaga, Rita C Reyburn, Catherine Satzke, Eric Rafai, E Kim Mulholland, Fiona M Russell

Journal article  |  2020  |  PLOS ONE

This study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji. We used data from four annual (2012-2..

Selective Persistence of HPV Cross-Neutralising Antibodies following Reduced-Dose HPV Vaccine Schedules

Zheng Quan Toh, Jennie Kosasih, Fiona M Russell, Rita Reyburn, James Fong, Evelyn Tuivaga, Felisita T Ratu, Cattram D Nguyen, Silivia Matanitobua, Lien Anh Ha Do, Trevelyan Menheniott, Ian H Frazer, Suzanne M Garland, Edward Kim Mulholland, Paul V Licciardi

Journal article  |  2019  |  Vaccines

The duration of cross-neutralising antibody responses (cross-NAb) following HPV immunisation is unknown. We compared cross-NAb res..

A Comparison of Pneumococcal Nasopharyngeal Carriage in Very Young Fijian Infants Born by Vaginal or Cesarean Delivery

Eleanor Frances Georgina Neal, Cattram Nguyen, Felista Tupou Ratu, Silivia Matanitobua, Eileen Margaret Dunne, Rita Reyburn, Mike Kama, Rachel Devi, Kylie M Jenkins, Lisi Tikoduadua, Joseph Kado, Eric Rafai, Catherine Satzke, Edward Kim Mulholland, Fiona Mary Russell

Journal article  |  2019  |  JAMA Network Open

Importance: Pneumococcal nasopharyngeal carriage is a prerequisite for pneumococcal disease. The main transmission route is from t..

Epidemiology of pneumonia in the pre-pneumococcal conjugate vaccine era in children 2-59 months of age, in Ulaanbaatar, Mongolia, 2015-2016

Claire von Mollendorf, Sophie La Vincente, Mukhchuluun Ulziibayar, Bujinlkham Suuri, Dashtseren Luvsantseren, Dorj Narangerel, John de Campo, Margaret de Campo, Cattram Nguyen, Sodbayar Demberelsuren, Tuya Mungun, E Kim Mulholland

Journal article  |  2019  |  PLOS ONE

BACKGROUND: Respiratory diseases, including pneumonia, are the second largest cause of under-five mortality in Mongolia and the mo..

Pneumococcal carriage, density, and co-colonization dynamics: A longitudinal study in Indonesian infants

Chrysanti Murad, Eileen M Dunne, Sunaryati Sudigdoadi, Eddy Fadlyana, Rodman Tarigan, Casey L Pell, Emma Watts, Cattram D Nguyen, Catherine Satzke, Jason Hinds, Mia Milanti Dewi, Meita Dhamayanti, Nanan Sekarwana, Kusnandi Rusmil, E Kim Mulholland, Cissy Kartasasmita

Journal article  |  2019  |  International Journal of Infectious Diseases

OBJECTIVES: Nasopharyngeal carriage of Streptococcus pneumoniae underpins disease development and transmission. This study was per..

The association between pneumococcal vaccination, ethnicity, and the nasopharyngeal microbiota of children in Fiji

Laura K Boelsen, Eileen M Dunne, Moana Mika, Stefanie Eggers, Cattram D Nguyen, F Tupou Ratu, Fiona M Russell, E Kim Mulholland, Markus Hilty, Catherine Satzke

Journal article  |  2019  |  Microbiome

BACKGROUND: Streptococcus pneumoniae is a significant global pathogen that colonises the nasopharynx of healthy children. Pneumoco..

Pneumococcal carriage in children in Ulaanbaatar, Mongolia before and one year after the introduction of the 13-valent pneumococcal conjugate vaccine

Claire von Mollendorf, Eileen M Dunne, Sophie La Vincente, Mukhchuluun Ulziibayar, Bujinlkham Suuri, Dashtseren Luvsantseren, Dorj Narangerel, Belinda D Ortika, Casey L Pell, Monica L Nation, Ahmed Alamrousi, Jason Hinds, Sodbayar Demberelsuren, Cattram Nguyen, Tuya Mungun, E Kim Mulholland, Catherine Satzke

Journal article  |  2019  |  Vaccine

BACKGROUND: Nasopharyngeal carriage of Streptococcus pneumoniae precedes disease, is the source of pneumococcal community spread, ..

Effect of a pneumococcal whole cell vaccine on influenza A-induced pneumococcal otitis media in infant mice

Jayne Manning, Eileen M Dunne, Nancy Wang, John S Pedersen, Jacqueline M Ogier, Rachel A Burt, E Kim Mulholland, Roy M Robins-Browne, Richard Malley, Odilia L Wijburg, Catherine Satzke

Journal article  |  2019  |  Vaccine

Immunogenicity and reactogenicity of ten-valent versus 13-valent pneumococcal conjugate vaccines among infants in Ho Chi Minh City, Vietnam: a randomised controlled trial

Beth Temple, Trong Toan Nguyen, Thi Trang Dai Vo, Kathryn Bright, Paul Vincent Licciardi, Rachel Ann Marimla, Cattram Duong Nguyen, Doan Y Uyen, Anne Balloch, Ngoc Huu Tran, Edward Kim Mulholland

Journal article  |  2019  |  The Lancet Infectious Diseases

Evaluation of a phased pneumococcal conjugate vaccine introduction in Mongolia using enhanced pneumonia surveillance and community carriage surveys: a study protocol for a prospective observational study and lessons learned

SF La Vincente, C von Mollendorf, M Ulziibayar, C Satzke, L Dashtseren, KK Fox, EM Dunne, CD Nguyen, J de Campo, M de Campo, H Thomson, G Surenkhand, S Demberelsuren, S Bujinlkham, LAH Do, D Narangerel, T Cherian, T Mungun, EK Mulholland

Journal article  |  2019  |  BMC Public Health

Pneumococcal vaccines in Nepal

Fiona M Russell, Kim Mulholland

Journal article  |  2019  |  The Lancet Infectious Diseases

Pneumococcal carriage in vaccine-eligible children and unvaccinated infants in Lao PDR two years following the introduction of the 13-valent pneumococcal conjugate vaccine

Catherine Satzke, Eileen M Dunne, Molina Choummanivong, Belinda D Ortika, Eleanor FG Neal, Casey L Pell, Monica L Nation, Kimberley K Fox, Cattram D Nguyen, Katherine A Gould, Jason Hinds, Anisone Chanthongthip, Anonh Xeuatvongsa, E Kim Mulholland, Vanphanom Sychareun, Fiona M Russell

Journal article  |  2019  |  Vaccine

Recombinant human papillomavirus nonavalent vaccine in the prevention of cancers caused by human papillomavirus

Zheng Quan Toh, Jennie Kosasih, Fiona M Russell, Suzanne M Garland, Edward K Mulholland, Paul Licciardi

Journal article  |  2019  |  Infection and Drug Resistance

Impact of the 23-valent pneumococcal polysaccharide vaccination in pregnancy against infant acute lower respiratory infections in the Northern Territory of Australia

Michael J Binks, Sarah A Moberley, Anne Balloch, Amanda J Leach, Sandra Nelson, Kim M Hare, Cate Wilson, Jane Nelson, Peter S Morris, Robert S Ware, Mimi LK Tang, Paul J Torzillo, Jonathan R Carapetis, Kim Mulholland, Ross M Andrews

Journal article  |  2018  |  Pneumonia

How long are children protected by influenza vaccination?

Anh Ha Do Lien, Kim Mulholland

Journal article  |  2018  |  The Lancet Respiratory Medicine

Effect of ten-valent pneumococcal conjugate vaccine introduction on pneumococcal carriage in Fiji: results from four annual cross-sectional carriage surveys

Eileen M Dunne, Catherine Satzke, Felisita T Ratu, Eleanor FG Neal, Laura K Boelsen, Silivia Matanitobua, Casey L Pell, Monica L Nation, Belinda D Ortika, Rita Reyburn, Kylie Jenkins, Cattram Nguyen, Katherine Gould, Jason Hinds, Lisi Tikoduadua, Joseph Kado, Eric Rafai, Mike Kama, E Kim Mulholland, Fiona M Russell

Journal article  |  2018  |  The Lancet Global Health

Discovery of a Streptococcus pneumoniae serotype 33F capsular polysaccharide locus that lacks wcjE and contains a wcyO pseudogene

Sam Manna, Eileen M Dunne, Belinda D Ortika, Casey L Pell, Mike Kama, Fiona M Russell, Tuya Mungun, E Kim Mulholland, Jason Hinds, Catherine Satzke

Journal article  |  2018  |  PLOS ONE

The clinical, immunological and microbiological impact of the 10-valent pneumococcal-Protein D conjugate vaccine in children with recurrent protracted bacterial bronchitis, chronic suppurative lung disease and bronchiectasis: A multi-centre, double-blind, randomised controlled trial

Kerry-Ann F O'Grady, Anne B Chang, Allan Cripps, Edward K Mulholland, Heidi Smith-Vaughan, Nicholas Wood, Margaret Danchin, Ruth Thornton, Andrew Wilson, Paul J Torzillo, Peter M Morris, Peter Richmond, Sheree Rablin, Daniel Arnold, Ann Connor, Vikas Goyal, Tanya Stoney, Kirsten Perrett, Keith Grimwood

Journal article  |  2018  |  Human Vaccines & Immunotherapeutics

Epidemiology of intussusception before and after rotavirus vaccine introduction in Fiji

Felisita Tupou Ratu, Rita Reyburn, Evelyn Tuivaga, Asena Tuiketei, Kylie Jenkins, Kim Mulholland, Adam Jenney, Fiona Russell

Journal article  |  2018  |  Scientific Reports

Cellular Immune Responses 6 Years Following 1, 2, or 3 Doses of Quadrivalent HPV Vaccine in Fijian Girls and Subsequent Responses to a Dose of Bivalent HPV Vaccine

Zheng Quan Toh, Kathleen Wen Bei Cheow, Fiona M Russell, Edwin Hoe, Rita Reyburn, James Fong, Evelyn Tuivaga, Felisita T Ratu, Cattram D Nguyen, Silivia Matanitobua, Andrea Reitsma, Sepehr N Tabrizi, Suzanne M Garland, Edward K Mulholland, Paul V Licciardi

Journal article  |  2018  |  Open Forum Infectious Diseases

Evaluation of different infant vaccination schedules incorporating pneumococcal vaccination (The Vietnam Pneumococcal Project): protocol of a randomised controlled trial

Beth Temple, Trong Toan Nguyen, Doan Y Uyen, Anne Balloch, Kathryn Bright, Yin Bun Cheung, Paul Licciardi, Duong Nguyen Cattram, Thi Minh Phuong Nguyen, Catherine Satzke, Heidi Smith-Vaughan, Que Huong Vu Thi, Ngoc Huu Tran, Edward Kim Mulhollan

Journal article  |  2018  |  BMJ Open

Epidemiology and risk factors for typhoid fever in Central Division, Fiji, 2014-2017: A case-control study

Namrata Prasad, Aaron P Jenkins, Lanieta Naucukidi, Varanisese Rosa, Aalisha Sahu-Khan, Mike Kama, Kylie M Jenkins, Adam WJ Jenney, Susan J Jack, Debasish Saha, Pierre Horwitz, Stacy D Jupiter, Richard A Strugnell, E Kim Mulholland, John A Crump

Journal article  |  2018  |  PLOS Neglected Tropical Diseases

Interlaboratory Comparison of the Pneumococcal Multiplex Opsonophagocytic Assays and Their Level of Agreement for Determination of Antibody Function in Pediatric Sera.

A Balloch, L Roalfe, N Ekstrom, CD Nguyen, L Spry, RA Marimla, PV Licciardi, D Goldblatt, EK Mulholland

Journal article  |  2018  |  mSphere

Opsonophagocytic assays are used to measure functional antibodies important in protection against pneumococcal capsular antigens. ..

Carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Indonesian children: A cross-sectional study

Eileen M Dunne, Chrysanti Murad, Sunaryati Sudigdoadi, Eddy Fadlyana, Rodman Tarigan, Sang Ayu Kompiyang Indriyani, Casey L Pell, Emma Watts, Catherine Satzke, Jason Hinds, Nurhandini Eka Dewi, Finny Fitry Yani, Kusnandi Rusmil, E Kim Mulholland, Cissy Kartasasmita

Journal article  |  2018  |  PLOS ONE

Problems with the WHO guidelines for management of childhood pneumonia

Kim Mulholland

Journal article  |  2018  |  The Lancet Global Health

Predicting the impact of pneumococcal conjugate vaccine programme options in Vietnam.

Olivier Le Polain De Waroux, W John Edmunds, Kensuke Takahashi, Koya Ariyoshi, E Kim Mulholland, David Goldblatt, Yoon Hong Choi, Dang Duc Anh, Lay Myint Yoshida, Stefan Flasche

Journal article  |  2018  |  Human Vaccines & Immunotherapeutics

Although catch-up campaigns (CCs) at the introduction of pneumococcal conjugate vaccines (PCVs) may accelerate their impact, suppl..

Cervical Cancer Prevention Through HPV Vaccination in Low- and Middle-Income Countries in Asia

Zheng Quan Toh, Paul V Licciardi, Fiona M Russell, Suzanne M Garland, Tsetsegsaikhan Batmunkh, Edward K Mulholland

Journal article  |  2017  |  Asian Pacific Journal of Cancer Prevention

Cervical cancer is ranked the first or second most common cancer in women of low- and middle-income countries (LMICs) in Asia. Cer..

A cross-sectional seroepidemiological survey of typhoid fever in Fiji.

Conall H Watson, Stephen Baker, Colleen L Lau, Kitione Rawalai, Mere Taufa, Jerimaia Coriakula, Nga Tran Vu Thieu, Tan Trinh Van, Dung Tran Thi Ngoc, Niel Hens, John H Lowry, Ruklanthi de Alwis, Jorge Cano, Kylie Jenkins, E Kim Mulholland, Eric J Nilles, Mike Kama, W John Edmunds

Journal article  |  2017  |  PLOS Neglected Tropical Diseases

Fiji, an upper-middle income state in the Pacific Ocean, has experienced an increase in confirmed case notifications of enteric fe..

Strongyloides seroprevalence before and after an ivermectin mass drug administration in a remote Australian Aboriginal community.

Therese M Kearns, Bart J Currie, Allen C Cheng, James McCarthy, Jonathan R Carapetis, Deborah C Holt, Wendy Page, Jennifer Shield, Roslyn Gundjirryirr, Eddie Mulholland, Linda Ward, Ross M Andrews

Journal article  |  2017  |  PLOS Neglected Tropical Diseases

BACKGROUND: Strongyloides seroprevalence is hyper-endemic in many Australian Aboriginal and Torres Strait Islander communities, ra..

Sustained Antibody Responses 6 Years Following 1, 2, or 3 Doses of Quadrivalent Human Papillomavirus (HPV) Vaccine in Adolescent Fijian Girls, and Subsequent Responses to a Single Dose of Bivalent HPV Vaccine: A Prospective Cohort Study

Zheng Quan Toh, Fiona M Russell, Rita Reyburn, James Fong, Evelyn Tuivaga, Tupou Ratu, Cattram D Nguyen, Rachel Devi, Mike Kama, Silivia Matanitobua, Sepehr N Tabrizi, Suzanne M Garland, Rohit Sinha, Ian Frazer, Lisi Tikoduadua, Joseph Kado, Eric Rafai, Edward K Mulholland, Paul V Licciardi

Journal article  |  2017  |  Clinical Infectious Diseases

Anti-Inflammatory Effects of Vitamin D on Human Immune Cells in the Context of Bacterial Infection

Edwin Hoe, Jordan Nathanielsz, Zheng Quan Toh, Leena Spry, Rachel Marimla, Anne Balloch, Kim Mulholland, Paul V Licciardi

Journal article  |  2016  |  Nutrients

An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

Vanessa K Wong, Stephen Baker, Thomas R Connor, Derek Pickard, Andrew J Page, Jayshree Dave, Niamh Murphy, Richard Holliman, Armine Sefton, Michael Millar, Zoe A Dyson, Gordon Dougan, Kathryn E Holt

Journal article  |  2016  |  Nature Communi

Investigation of Streptococcus salivarius-mediated inhibition of pneumococcal adherence to pharyngeal epithelial cells

Jayne Manning, Eileen M Dunne, Philip A Wescombe, John DF Hale, E Kim Mulholland, John R Tagg, Roy M Robins-Browne, Catherine Satzke

Journal article  |  2016  |  BMC Microbiology

Status of research and development of vaccines for Streptococcus pyogenes

Andrew C Steer, Jonathan R Carapetis, James B Dale, John D Fraser, Michael F Good, Luiza Guilherme, Nicole J Moreland, E Kim Mulholland, Florian Schodel, Pierre R Smeesters

Journal article  |  2016  |  Vaccine

No long-term evidence of hyporesponsiveness after use of pneumococcal conjugate vaccine in children previously immunized with pneumococcal polysaccharide vaccine

Paul V Licciardi, Zheng Quan Toh, Elizabeth A Clutterbuck, Anne Balloch, Rachel A Marimla, Leena Tikkanen, Karen E Lamb, Kathryn J Bright, Uraia Rabuatoka, Lisi Tikoduadua, Laura K Boelsen, Eileen M Dunne, Catherine Satzke, Yin Bun Cheung, Andrew J Pollard, Fiona M Russell, Edward K Mulholland

Journal article  |  2016  |  Journal of Allergy and Clinical Immunology

Implementation of a national school-based Human Papillomavirus (HPV) vaccine campaign in Fiji: knowledge, vaccine acceptability and information needs of parents

SF La Vincente, D Mielnik, K Jenkins, F Bingwor, L Volavola, H Marshall, P Druavesi, FM Russell, K Lokuge, EK Mulholland

Journal article  |  2015  |  BMC Public Health

PneuMum: Impact from a randomised controlled trial of maternal 23-valent pneumococcal polysaccharide vaccination on middle ear disease amongst Indigenous infants, Northern Territory, Australia

Michael J Binks, Sarah A Moberley, Anne Balloch, Amanda J Leach, Sandra Nelson, Kim M Hare, Cate Wilson, Peter S Morris, Jane Nelson, Mark D Chatfield, Mimi LK Tang, Paul Torzillo, Jonathan R Carapetis, E Kim Mulholland, Ross M Andrews

Journal article  |  2015  |  Vaccine

The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage in Vaccine Evaluation Studies

Catherine Satzke, Eileen M Dunne, Barbara D Porter, Keith P Klugman, E Kim Mulholland

Journal article  |  2015  |  PLOS Medicine

Long-term impact of pneumococcal polysaccharide vaccination on nasopharyngeal carriage in children previously vaccinated with various pneumococcal conjugate vaccine regimes

Laura K Boelsen, Eileen M Dunne, Karen E Lamb, Kathryn Bright, Yin Bun Cheung, Lisi Tikoduadua, Fiona M Russell, E Kim Mulholland, Paul V Licciardi, Catherine Satzke

Journal article  |  2015  |  Vaccine

Impact of an Ivermectin Mass Drug Administration on Scabies Prevalence in a Remote Australian Aboriginal Community

Therese M Kearns, Richard Speare, Allen C Cheng, James McCarthy, Jonathan R Carapetis, Deborah C Holt, Bart J Currie, Wendy Page, Jennifer Shield, Roslyn Gundjirryirr, Leanne Bundhala, Eddie Mulholland, Mark Chatfield, Ross M Andrews

Journal article  |  2015  |  PLOS Neglected Tropical Diseases

Reduced dose human papillomavirus vaccination: An update of the current state-of-the-art

Zheng Quan Toh, Paul V Licciardi, James Fong, Suzanne M Garland, Sepehr N Tabrizi, Fiona M Russell, Edward K Mulholland

Journal article  |  2015  |  Vaccine

Characterization of 19A-like 19F pneumococcal isolates from Papua New Guinea and Fiji.

EM Dunne, L Tikkanen, A Balloch, K Gould, M Yoannes, S Phuanukoonnon, PV Licciardi, FM Russell, EK Mulholland, C Satzke, J Hinds

Journal article  |  2015  |  New Microbes and New Infections

Molecular identification of Streptococcus pneumoniae serotype 19F is routinely performed by PCR targeting the wzy gene of the caps..

Reduced IL-17A Secretion Is Associated with High Levels of Pneumococcal Nasopharyngeal Carriage in Fijian Children

Edwin Hoe, Laura K Boelsen, Zheng Quan Toh, Guang Wen Sun, Ghee Chong Koo, Anne Balloch, Rachel Marimla, Eileen M Dunne, Lisi Tikoduadua, Fiona M Russell, Catherine Satzke, E Kim Mulholland, Paul V Licciardi

Journal article  |  2015  |  PLOS ONE

Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

Vanessa K Wong, Stephen Baker, Derek J Pickard, Julian Parkhill, Andrew J Page, Nicholas A Feasey, Robert A Kingsley, Nicholas R Thomson, Jacqueline A Keanel, Francois-Xavier Weill, David J Edwards, Jane Hawkey, Simon R Harris, Alison E Mather, Amy K Cain, James Hadfield, Peter J Hart, Tran Vu Thieu Nga, Elizabeth J Klemm, Dafni A Glinos, et al.

Journal article  |  2015  |  Nature Genetics

Antibiotic trials for community-acquired pneumonia--authors' reply.

Kim Mulholland, John Carlin, Trevor Duke, Martin Weber

Journal article  |  2015  |  The Lancet Respiratory Medicine

Pneumococcal conjugate vaccines PREVenar13 and SynflorIX in sequence or alone in high-risk Indigenous infants (PREV-IX_COMBO): protocol of a randomised controlled trial

Amanda Jane Leach, Edward Kim Mulholland, Mathu Santosham, Paul John Torzillo, Ngiare Joy Brown, Peter McIntyre, Heidi Smith-Vaughan, Sue Skull, Anne Balloch, Ross Andrews, Jonathan Carapetis, Joseph McDonnell, Vicki Krause, Peter Stanley Morris

Journal article  |  2015  |  BMJ Open

Early indication for a reduced burden of radiologically confirmed pneumonia in children following the introduction of routine vaccination against Haemophilus influenzae type b in Nha Trang, Vietnam.

Stefan Flasche, Kensuke Takahashi, Dinh Thiem Vu, Motoi Suzuki, Thi Hien-Anh Nguyen, HuuTho Le, Masahiro Hashizume, Duc Anh Dang, Karen Edmond, Koya Ariyoshi, E Kim Mulholland, W John Edmunds, Lay-Myint Yoshida

Journal article  |  2014  |  Vaccine

INTRODUCTION: Despite the global success of Hib vaccination in reducing disease and mortality, uncertainty about the disease burde..

The challenges of trials of antibiotics for pneumonia in low-income countries

Kim Mulholland, John B Carlin, Trevor Duke, Martin Weber

Journal article  |  2014  |  The Lancet Respiratory Medicine

Crusted scabies in remote Australia, a new way forward: lessons and outcomes from the East Arnhem Scabies Control Program.

Buddhi Lokuge, Alex Kopczynski, Angela Woltmann, Faye Alvoen, Christine Connors, Terrence Guyula, Eddie Mulholland, Samantha Cran, Tim Foster, Kamalini Lokuge, Tanya Burke, Sam Prince

Journal article  |  2014  |  Medical Journal of Australia

Crusted scabies is a highly infectious, debilitating and disfiguring disease, and remote Aboriginal communities of northern Austra..

Impaired serotype-specific immune function following pneumococcal vaccination in infants with prior carriage

Paul V Licciardi, Fiona M Russell, Anne Balloch, Robert L Burton, Moon H Nahm, Gwendolyn Gilbert, Mimi LK Tang, Edward K Mulholland

Journal article  |  2014  |  Vaccine

Comparison of Anti-pneumococcal Antibodies in Cord Blood From Australian Indigenous and Gambian Neonates and the Implications for Otitis Media

Anne Balloch, Paul V Licciardi, Andrew S Kemp, Amanda J Leach, E Kim Mulholland, Mimi LK Tang

Journal article  |  2014  |  Pediatric Infectious Disease Journal

Does a 10-valent pneumococcal-Haemophilus influenzae protein D conjugate vaccine prevent respiratory exacerbations in children with recurrent protracted bacterial bronchitis, chronic suppurative lung disease and bronchiectasis: protocol for a randomised controlled trial.

Kerry-Ann F O'Grady, Keith Grimwood, Allan Cripps, Edward K Mulholland, Peter Morris, Paul J Torzillo, Nicholas Wood, Heidi Smith-Vaughan, Amber Revell, Andrew Wilson, Peter Van Asperen, Peter Richmond, Ruth Thornton, Sheree Rablin, Anne B Chang

Journal article  |  2013  |  Trials

BACKGROUND: Recurrent protracted bacterial bronchitis (PBB), chronic suppurative lung disease (CSLD) and bronchiectasis are charac..

Nasopharyngeal microbial interactions in the era of pneumococcal conjugate vaccination

Eileen M Dunne, Heidi C Smith-Vaughan, Roy M Robins-Browne, E Kim Mulholland, Catherine Satzke

Journal article  |  2013  |  Vaccine

Group A streptococcal vaccines: Paving a path for accelerated development

James B Dale, Vincent A Fischetti, Jonathan R Carapetis, Andrew C Steer, Samba Sow, Rajesh Kumar, Bongani M Mayosi, Fran A Rubin, Kim Mulholland, Joachim Maria Hombach, Florian Schoedel, Ana Maria Henao-Restrepo

Journal article  |  2013  |  Vaccine

Inhibition of Streptococcus pneumoniae adherence to human epithelial cells in vitro by the probiotic Lactobacillus rhamnosus GG.

Sook-San Wong, Zheng Quan Toh, Eileen M Dunne, E Kim Mulholland, Mimi LK Tang, Roy M Robins-Browne, Paul V Licciardi, Catherine Satzke

Journal article  |  2013  |  BMC Research Notes

BACKGROUND: Colonization of the nasopharynx by Streptococcus pneumoniae is considered a prerequisite for pneumococcal infections s..

The high burden of cervical cancer in Fiji, 2004-07

Irwin Law, James J Fong, Eka M Buadromo, Josaia Samuela, Mahomed S Patel, Suzanne M Garland, E Kim Mulholland, Fiona M Russell

Journal article  |  2013  |  Sexual Health

Protecting against Pneumococcal Disease: Critical Interactions between Probiotics and the Airway Microbiome

Paul V Licciardi, Zheng Quan Toh, Eileen Dunne, Sook-San Wong, Edward K Mulholland, Mimi Tang, Roy M Robins-Browne, Catherine Satzke

Journal article  |  2012  |  PLoS Pathogens

Measles in the 21st Century

E Kim Mulholland, Ulla Kou Griffiths, Robin Biellik

Journal article  |  2012  |  New England Journal of Medicine

Meningitis in children in Fiji: etiology, epidemiology, and neurological sequelae

Viema Lewagalu Biaukula, Lisi Tikoduadua, Kristy Azzopardi, Anna Seduadua, Beth Temple, Peter Richmond, Roy Robins-Browne, Edward Kim Mulholland, Fiona Mary Russell

Journal article  |  2012  |  International Journal of Infectious Diseases

Effect of Pneumococcal Vaccination on Nasopharyngeal Carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Staphylococcus aureus in Fijian Children

Eileen M Dunne, Jayne Manning, Fiona M Russell, Roy M Robins-Browne, E Kim Mulholland, Catherine Satzke

Journal article  |  2012  |  Journal of Clinical Microbiology

Pneumococcal polysaccharide vaccine at 12 months of age produces functional immune responses

Paul V Licciardi, Anne Balloch, Fiona M Russell, Robert L Burton, Jisheng Lin, Moon H Nahm, Edward K Mulholland, Mimi LK Tang

Journal article  |  2012  |  Journal of Allergy and Clinical Immunology

The cost of outpatient pneumonia in children < 5 years of age in Fiji

Beth Temple, Ulla Kou Griffiths, Edward Kim Mulholland, Felisita Tupou Ratu, Lisi Tikoduadua, Fiona Mary Russell

Journal article  |  2012  |  Tropical Medicine & International Health

Multilocus Sequence Typing of Streptococcus pneumoniae by Use of Mass Spectrometry

Eileen M Dunne, Eng Kok Ong, Ralf J Moser, Peter M Siba, Suparat Phuanukoonnon, Andrew R Greenhill, Roy M Robins-Browne, E Kim Mulholland, Catherine Satzke

Journal article  |  2011  |  Journal of Clinical Microbiology

Serotype-specific avidity is achieved following a single dose of the 7-valent pneumococcal conjugate vaccine, and is enhanced by 23-valent pneumococcal polysaccharide booster at 12 months

FM Russell, A Balloch, PV Licciardi, JR Carapetis, L Tikoduadua, L Waqatakirewa, YB Cheung, EK Mulholland, MLK Tang

Journal article  |  2011  |  Vaccine

Age-and serotype-dependent antibody response to pneumococcal polysaccharides Reply

Anne Balloch, Paul V Licciardi, Fiona M Russell, Edward K Mulholland, Mimi LK Tang

Journal article  |  2011  |  Journal of Allergy and Clinical Immunology

Opsonophagocytic activity following a reduced dose 7-valent pneumococcal conjugate vaccine infant primary series and 23-valent pneumococcal polysaccharide vaccine at 12 months of age

FM Russell, JR Carapetis, RL Burton, J Lin, PV Licciardi, A Balloch, L Tikoduadua, L Waqatakirewa, YB Cheung, MLK Tang, MH Nahm, EK Mulholland

Journal article  |  2011  |  Vaccine

Human papillomavirus genotype prevalence in cervical biopsies from women diagnosed with cervical intraepithelial neoplasia or cervical cancer in Fiji

Sepehr N Tabrizi, Irwin Law, Eka Buadromo, Matthew P Stevens, James Fong, Josaia Samuela, Mahomed Patel, E Kim Mulholland, Fiona M Russell, Suzanne M Garland

Journal article  |  2011  |  Sexual Health

Pneumococcal Nasopharyngeal Carriage following Reduced Doses of a 7-Valent Pneumococcal Conjugate Vaccine and a 23-Valent Pneumococcal Polysaccharide Vaccine Booster

FM Russell, JR Carapetis, C Satzke, L Tikoduadua, L Waqatakirewa, R Chandra, A Seduadua, S Oftadeh, YB Cheung, GL Gilbert, EK Mulholland

Journal article  |  2010  |  Clinical and Vaccine Immunology

Molecular Epidemiology of Streptococcus pneumoniae Serogroup 6 Isolates from Fijian Children, Including Newly Identified Serotypes 6C and 6D

Catherine Satzke, Belinda D Ortika, Shahin Oftadeh, Fiona M Russell, Roy M Robins-Browne, E Kim Mulholland, Gwendolyn L Gilbert

Journal article  |  2010  |  Journal of Clinical Microbiology

Supporting new vaccine introduction decisions: lessons learned from the Hib Initiative experience.

RA Hajjeh, L Privor-Dumm, K Edmond, R O'Loughlin, S Shetty, UK Griffiths, AP Bear, AL Cohen, A Chandran, A Schuchat, EK Mulholland, M Santosham

Journal article  |  2010  |  Vaccine

The introduction of Haemophilus influenzae type b (Hib) vaccine in developing countries has suffered from a long delay. Between 20..

Comparison of Citrated Human Blood, Citrated Sheep Blood, and Defibrinated Sheep Blood Mueller-Hinton Agar Preparations for Antimicrobial Susceptibility Testing of Streptococcus pneumoniae Isolates

Catherine Satzke, Anna Seduadua, Reginald Chandra, Jonathan R Carapetis, E Kim Mulholland, Fiona M Russell

Journal article  |  2010  |  Journal of Clinical Microbiology

INVASIVE PNEUMOCOCCAL DISEASE IN FIJI CLINICAL SYNDROMES, EPIDEMIOLOGY, AND THE POTENTIAL IMPACT OF PNEUMOCOCCAL CONJUGATE VACCINE

Fiona Mary Russell, Jonathan Rhys Carapetis, Lisi Tikoduadua, Reginald Chandra, Anna Seduadua, Catherine Satzke, Jan Pryor, Eka Buadromo, Lepani Waqatakirewa, Edward Kim Mulholland

Journal article  |  2010  |  Pediatric Infectious Disease Journal

Erratum: Pneumonia research to reduce childhood mortality in the developing world (The Journal of Clinical Investigation (2008), 118, 4 (1291-1300) DOI: 10.1172/JCI33947)

JAG Scott, WA Brooks, JSM Peiris, D Holtzman, EK Mulholland

Journal article  |  2010  |  Journal of Clinical Investigation

Infants aged 12 months can mount adequate serotype-specific IgG responses to pneumococcal polysaccharide vaccine

Anne Balloch, Paul V Licciardi, Fiona M Russell, Edward K Mulholland, Mimi LK Tang

Journal article  |  2010  |  Journal of Allergy and Clinical Immunology

Confidence in vaccines in developing countries: social, cultural, economic and political influences.

K Mulholland, V Korczak, V Tangcharoensathien

Journal article  |  2010  |  Journal of Epidemiology & Community Health

Antibodies to serotype 9V exhibit novel serogroup cross-reactivity following infant pneumococcal immunization

PV Licciardi, A Balloch, FM Russell, EK Mulholland, MLK Tang

Journal article  |  2010  |  Vaccine

Hyporesponsiveness to re-challenge dose following pneumococcal polysaccharide vaccine at 12 months of age, a randomized controlled trial

FM Russell, JR Carapetis, A Balloch, PV Licciardi, AWJ Jenney, L Tikoduadua, L Waqatakirewa, J Pryor, J Nelson, GB Byrnes, YB Cheung, MLK Tang, EK Mulholland

Journal article  |  2010  |  Vaccine

Safety and immunogenicity of the 23-valent pneumococcal polysaccharide vaccine at 12 months of age, following one, two, or three doses of the 7-valent pneumococcal conjugate vaccine in infancy

FM Russell, PV Licciardi, A Balloch, V Biaukula, L Tikoduadua, JR Carapetis, J Nelson, AWJ Jenney, L Waqatakirewa, S Colquhoun, YB Cheung, MLK Tang, EK Mulholland

Journal article  |  2010  |  Vaccine

Increased Risk of Hospitalization for Acute Lower Respiratory Tract Infection among Australian Indigenous Infants 5-23 Months of Age Following Pneumococcal Vaccination: A Cohort Study

Kerry-Ann F O'Grady, Katherine J Lee, John B Carlin, Paul J Torzillo, Anne B Chang, E Kim Mulholland, Stephen B Lambert, Ross M Andrews

Journal article  |  2010  |  Clinical Infectious Diseases

Group A streptococcal vaccines: facts versus fantasy

Andrew C Steer, Michael R Batzloff, Kim Mulholland, Jonathan R Carapetis

Journal article  |  2009  |  Current Opinion in Infectious Diseases

The burden of hospitalised rotavirus infections in Fiji

Adam Jenney, Lisi Tikoduadua, Eka Buadromo, Graeme Barnes, Carl D Kirkwood, Karen Boniface, Julie Bines, Kim Mulholland, Fiona Russell

Journal article  |  2009  |  Vaccine

Immunogenicity following one, two, or three doses of the 7-valent pneumococcal conjugate vaccine

FM Russell, A Balloch, MLK Tang, JR Carapetis, P Licciardi, J Nelson, AWJ Jenney, L Tikoduadua, L Waqatakirewa, J Pryor, GB Byrnes, YB Cheung, EK Mulholland

Journal article  |  2009  |  Vaccine

Prospective Surveillance of Streptococcal Sore Throat in a Tropical Country

Andrew C Steer, Adam WJ Jenney, Joseph Kado, Michael F Good, Michael Batzloff, Graham Magor, Roselyn Ritika, Kim E Mulholland, Jonathan R Carapetis

Journal article  |  2009  |  Pediatric Infectious Disease Journal

High Burden of Impetigo and Scabies in a Tropical Country

Andrew C Steer, Adam WJ Jenney, Joseph Kado, Michael R Batzloff, Sophie La Vincente, Lepani Waqatakirewa, E Kim Mulholland, Jonathan R Carapetis

Journal article  |  2009  |  PLoS Neglected Tropical Diseases

Reduction of meningitis and impact on under-5 pneumonia after introducing the Hib vaccine in the Kingdom of Tonga

FM Russell, T Fakakovi, S Paasi, A Ika, EK Mulholland

Journal article  |  2009  |  Annals of Tropical Paediatrics

High Prevalence of Rheumatic Heart Disease by Clinical and Echocardiographic Screening among Children in Fiji

Andrew C Steer, Joseph Kado, Nigel Wilson, Timaima Tuiketei, Michael Batzloff, Lepani Waqatakirewa, E Kim Mulholland, Jonathan R Carapetis

Journal article  |  2009  |  Journal of Heart Valve Disease

Recommendations for treatment of childhood non-severe pneumonia

Gavin B Grant, Harry Campbell, Scott F Dowell, Stephen M Graham, Keith P Klugman, E Kim Mulholland, Mark Steinhoff, Martin W Weber, Shamim Qazi

Journal article  |  2009  |  The Lancet Infectious Diseases

Acute rheumatic fever and rheumatic heart disease in Fiji: prospective surveillance, 2005-2007

Andrew C Steer, Joseph Kado, Adam WJ Jenney, Michael Batzloff, Lepani Waqatakirewa, E Kim Mulholland, Jonathan R Carapetis

Journal article  |  2009  |  Medical Journal of Australia

Prospective Surveillance of Invasive Group A Streptococcal Disease, Fiji, 2005-2007

Andrew C Steer, Adam Jenney, Joseph Kado, Michael F Good, Michael Batzloff, Lepani Waqatakirewa, E Kim Mullholland, Jonathan R Carapetis

Journal article  |  2009  |  Emerging Infectious Diseases

Optimising the use of conjugate vaccines to prevent disease caused by Haemophilus influenzae type b, Neisseria meningitidis and Streptococcus pneumoniae

Caroline L Trotter, Jodie McVernon, Mary E Ramsay, Cynthia G Whitney, E Kim Mulholland, David Goldblatt, Joachim Hombach, Marie-Paule Kieny

Journal article  |  2008  |  Vaccine

Vaccine-preventable haemophilus influenza type B disease burden and cost-effectiveness of infant vaccination in Indonesia.

Bradford D Gessner, Endang R Sedyaningsih, Ulla K Griffiths, Agustinus Sutanto, Mary Linehan, Dave Mercer, Edward Kim Mulholland, Damian G Walker, Mark Steinhoff, Mardiati Nadjib

Journal article  |  2008  |  The Pediatric Infectious Disease Journal

BACKGROUND: Most of Asia, including Indonesia, does not use Haemophilus influenzae type b (Hib) conjugate vaccines. We estimated t..

Equity and child-survival strategies.

Ek Mulholland, L Smith, I Carneiro, H Becher, D Lehmann

Journal article  |  2008  |  Bulletin of the World Health Organization

Recent advances in child survival have often been at the expense of increasing inequity. Successive interventions are applied to t..

Pneumonia research to reduce childhood mortality in the developing world.

J Anthony G Scott, W Abdullah Brooks, JS Malik Peiris, Douglas Holtzman, E Kim Mulholland

Journal article  |  2008  |  Journal of Clinical Investigation

Pneumonia is an illness, usually caused by infection, in which the lungs become inflamed and congested, reducing oxygen exchange a..

Childhood pneumonia mortality - a permanent global emergency

Kim Mulholland

Journal article  |  2007  |  The Lancet

Childhood pneumonia - preventing the world's biggest killer of children

Brian M Greenwood, Martin W Weber, Kim Mulholland

Journal article  |  2007  |  Bulletin of the World Health Organization

New Zealand epidemic strain meningococcal B outer membrane vesicle vaccine in children aged 16-24 months

Sharon Wong, Diana Lennon, Catherine Jackson, Joanna Stewart, Stewart Reid, Sue Crengle, Sandrine Tilman, Ingeborg Aaberge, Jane O'Hallahan, Philipp Oster, Kim Mulholland, Diana Martin

Journal article  |  2007  |  Pediatric Infectious Disease Journal

Perspectives on the burden of pneumonia in children

Kim Mulholland

Journal article  |  2007  |  Vaccine

As a bacterial culture medium, citrated sheep blood agar is a practical alternative to citrated human blood agar in laboratories of developing countries

FM Russell, SSN Biribo, G Selvaraj, F Oppedisano, S Warren, A Seduadua, EK Mulholland, JR Carapetis

Journal article  |  2006  |  Journal of Clinical Microbiology

Pneumococcal nasopharyngeal carriage and patterns of penicillin resistance in young children in Fiji

FM Russell, JR Carapetis, S Ketaiwai, V Kunabuli, M Taoi, S Biribo, A Seduadua, EK Mulholland

Journal article  |  2006  |  Annals of Tropical Paediatrics

Measles in the United States, 2006.

E Kim Mulholland

Journal article  |  2006  |  New England Journal of Medicine

Validation of clinical case definition of acute intussusception in infants in Viet Nam and Australia

Julie E Bines, Nguyen Thanh Liem, Frances Justice, Tran Ngoc Son, John B Carlin, Margaret de Campo, Kris Jamsen, Kim Mulholland, Peter Barnett, Graeme L Barnes

Journal article  |  2006  |  Bulletin of the World Health Organization

The role of Chlamydia pneumoniae in acute respiratory tract infections in young children in The Gambia, West Africa.

Martin W Weber, Gowri Gopalakrishna, Agnes Awomoyi, Adam Cunningham, Richard A Adegbola, Adegoke G Falade, Olayinka O Ogunlesi, Hilton C Whittle, E Kim Mulholland

Journal article  |  2006  |  Annals of Tropical Paediatrics

BACKGROUND: Little is known about the role of Chlamydia pneumoniae in the aetiology of acute respiratory tract infections (ARI) in..

Safety and immunogenicity of New Zealand strain meningococcal serogroup BOMV vaccine in healthy adults: Beginning of epidemic control

V Thornton, D Lennon, K Rasanathan, J O'Hallahan, P Oster, J Stewart, S Tilman, I Aaberge, B Feiring, H Nokleby, E Rosenqvist, K White, S Reid, K Mulholland, MJ Wakefield, D Martin

Journal article  |  2006  |  Vaccine

The global burden of group A streptococcal diseases

JR Carapetis, AC Steer, EK Mulholland, M Weber

Journal article  |  2005  |  The Lancet Infectious Diseases

Reaching the unreached with measles vaccination

P Salama, J McFarland, K Mulholland

Journal article  |  2005  |  The Lancet

Prognostic/Clinical Prediction Models: Development of a Clinical Prediction Model for an Ordinal Outcome: The World Health Organization Multicentre Study of Clinical Signs and Etiological Agents of Pneumonia, Sepsis and Meningitis in Young Infants

FE Harrell, PA Margolis, S Gove, KE Mason, EK Mulholland, D Lehmann, L Muhe, S Gatchalian, HF Eichenwald

Book Chapter  |  2005

Editorial: The Gambian pneumococcal vaccine trial - implications for control of childhood pneumonia

K Mulholland

Journal article  |  2005  |  Tropical Medicine & International Health

Chest x-ray-confirmed pneumonia in children in Fiji

HC Magree, FM Russell, R Sa'aga, P Greenwood, L Tikoduadua, J Pryor, L Waqatakirewa, JR Carapetis, EK Mulholland

Journal article  |  2005  |  Bulletin of the World Health Organization

Isoniazid treatment of children: can genetics help guide treatment?

N Cranswick, K Mulholland

Journal article  |  2005  |  Archives of Disease in Childhood: Education and Practice Edition

Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies

T Cherian, EK Mulholland, JB Carlin, H Ostensen, R Amin, M de Campo, D Greenberg, R Lagos, M Lucero, SA Madhi, KL O'Brien, S Obaro, MC Steinhoff

Journal article  |  2005  |  Bulletin of the World Health Organization

Commentary: Comorbidity as a factor in child health and child survival in developing countries

K Mulholland

Journal article  |  2005  |  International Journal of Epidemiology

Evaluating the post-licensure effectiveness of a group B meningococcal vaccine in New Zealand: a multi-faceted strategy

S Ameratunga, A Macmillan, J Stewart, D Scott, K Mulholland, S Crengle

Journal article  |  2005  |  Vaccine

MeNZB (TM): a safe and highly immunogenic tailor-made vaccine against the New Zealand Neisseria meningitidis serogroup B disease epidemic strain

P Oster, D Lennon, J O'Hallahan, K Mulholland, S Reid, D Martin

Journal article  |  2005  |  Vaccine

From secondary prevention to primary prevention: a unique strategy that gives hope to a country ravaged by meningococcal disease

J O'Hallahan, D Lennon, P Oster, R Lane, S Reid, K Mulholland, J Stewart, L Penney, T Percival, D Martin

Journal article  |  2005  |  Vaccine

Bacterial infections - A major cause of death among children in Africa

EK Mulholland, RA Adegbola

Journal article  |  2005  |  New England Journal of Medicine

Immunisation at the crossroads: 9th National Immunisation/1st Asia-Pacific Vaccine Preventable Diseases Conference.

Peter B McIntyre, Heath A Kelly, E Kim Mulholland

Conference Proceedings  |  2005  |  Medical Journal of Australia

Recent advances in pneumococcal vaccination of children

FM Russell, EK Mulholland

Journal article  |  2004  |  Annals of Tropical Paediatrics

Clinical case definition for the diagnosis of acute intussusception

JE Bines, T Ivanoff, F Justice, K Mulholland

Journal article  |  2004  |  Journal of Pediatric Gastroenterology and Nutrition

Hospital-based case-control study of bronchiectasis in indigenous children in central Australia

PC Valery, PJ Torzillo, K Mulholland, NC Boyce, DM Purdie, AB Chang

Journal article  |  2004  |  Pediatric Infectious Disease Journal

Use of vaccine trials to estimate burden of disease.

E Kim Mulholland

Journal article  |  2004  |  Journal of Health, Population and Nutrition

Vaccine trials, the most informative way of determining the efficacy of a vaccine, can also provide valuable information about the..

The use of CRP for diagnosing infections in young infants < 3 months of age in developing countries

A Palmer, JB Carlin, J Freihorst, S Gatchalian, L Muhe, K Mulholland, MW Weber

Journal article  |  2004  |  Annals of Tropical Paediatrics

The New Zealand Meningococcal Vaccine Strategy: a tailor-made vaccine to combat a devastating epidemic.

Kerry Sexton, Diana Lennon, Philipp Oster, Sue Crengle, Diana Martin, Kim Mulholland, Teuila Percival, Stewart Reid, Joanna Stewart, Jane O'Hallahan

Journal article  |  2004  |  New Zealand Medical Journal

The New Zealand Meningococcal Vaccine Strategy aims to end the devastating 14-year epidemic of B:4:P1.7b,4 group B meningococcal d..

Haemophilus influenzae type b infection in children in Pacific countries.

JR Carapetis, FM Russell, O Mansoor, A Darcy, T Fakakovi, A Metai, NT Potoi, N Wilson, EK Mulholland

Journal article  |  2004  |  Pacific health dialog : a publication of the Pacific Basin Officers Training Program and the Fiji School of Medicine

The Haemophilus influenzae type b (Hib) disease burden among children under five years in four Pacific island countries (PIC was e..

Global control of rotavirus disease

EK Mulholland

Book Chapter  |  2004  |  Advances in Experimental Medicine and Biology

High incidence of Haemophilus influenzae type b infection in children in Pacific Island countries

FM Russell, JR Carapetis, O Mansoor, A Darcy, T Fakakovi, A Metai, NT Potoi, N Wilson, EK Mulholland

Journal article  |  2003  |  Clinical Infectious Diseases

Global burden of pediatric respiratory illness and the implications for management and prevention

HJ Zar, K Mulholland

Journal article  |  2003  |  Pediatric Pulmonology

Global burden of acute respiratory infections in children: Implications for interventions

K Mulholland

Journal article  |  2003  |  Pediatric Pulmonology

Predictors of neonatal sepsis in developing countries

MW Weber, JB Carlin, S Gatchalian, D Lehmann, L Muhe, EK Mulholland

Journal article  |  2003  |  Pediatric Infectious Disease Journal

Introduction of New Vaccines in the Healthcare System

EK Mulholland, B Bjorvatn

Book Chapter  |  2003

Evidence on the use of paracetamol in febrile children

FM Russell, F Shann, N Curtis, K Mulholland

Journal article  |  2003  |  Bulletin of the World Health Organization

Clinical predictors of bacterial meningitis in infants and young children in The Gambia

MW Weber, J Herman, S Jaffar, S Usen, A Oparaugo, C Omosigho, RA Adegbola, BM Greenwood, EK Mulholland

Journal article  |  2002  |  Tropical Medicine & International Health

Bronchiectasis in indigenous children in remote Australian communities.

Anne B Chang, Keith Grimwood, E Kim Mulholland, Paul J Torzillo, undefined Working Group on Indigenous Paediatric Respiratory Health

Journal article  |  2002  |  Medical Journal of Australia

The rates of bronchiectasis for Indigenous children from remote Australian communities are unacceptably high, with one study showi..

An epidemiological study of RSV infection in the Gambia

MW Weber, P Milligan, M Sanneh, A Awemoyi, ER Dakour, G Schneider, A Palmer, M Jallow, A Oparaogu, H Whittle, EK Mulholland, BM Greenwood

Journal article  |  2002  |  Bulletin of the World Health Organization

Bronchiectasis in Indigenous children in remote Australian communities

AB CHANG, KG GRIMWOOD, EK MULHOLLAND, PJ TORZILLO

Journal article  |  2002  |  Medical Journal of Australia

Prevention of otitis media by vaccination

F Russell, K Mulholland

Journal article  |  2002  |  Drugs

Respiratory rate as a predictor of positive lung aspirates in young Gambian children with lobar pneumonia

AG Falade, RA Adegbola, EK Mulholland, BM Greenwood

Journal article  |  2001  |  Annals of Tropical Paediatrics

Pneumococcal conjugate vaccine--relevance for developing countries.

K Mulholland

Journal article  |  2001  |  Indian Pediatrics

Routine vaccination and child survival in Guinea-Bissau - Lessons can be learnt from this study

K Mulholland, ML Barreto

Journal article  |  2001  |  British Medical Journal

Standardisation of interpretation of chest radiographs for the diagnosis of pneumonia in children

JB CARLIN, EK MULHOLLAND, TM NOLAN

Report  |  2001

Conjugate pneumococcal vaccines: an overview.

EK Mulholland

Journal article  |  2000  |  Medical Journal of Australia

A seven-valent conjugate pneumococcal vaccine has been shown to have dramatic efficacy against invasive pneumococcal disease and l..

Outcome of meningitis caused by Streptococcus pneumoniae and Haemophilus influenzae type b in children in The Gambia.

T Goetghebuer, TE West, V Wermenbol, AL Cadbury, P Milligan, N Lloyd-Evans, RA Adegbola, EK Mulholland, BM Greenwood, MW Weber

Journal article  |  2000  |  Tropical Medicine and International Health

In developing countries, endemic childhood meningitis is a severe disease caused most commonly by Streptococcus pneumoniae or Haem..

Chloramphenicol pharmacokinetics in infants less than three months of age in the Philippines and The Gambia.

MW Weber, SR Gatchalian, O Ogunlesi, A Smith, GH McCracken, S Qazi, AF Weber, K Olsen, EK Mulholland

Journal article  |  1999  |  The Pediatric Infectious Disease Journal

BACKGROUND: The broad antimicrobial spectrum and affordable price of chloramphenicol make it an attractive first line treatment op..

Clinical prediction of serious bacterial infections in young infants in developing countries. The WHO Young Infants Study Group.

Journal article  |  1999  |  The Pediatric Infectious Disease Journal

Etiology of pneumonia, sepsis and meningitis in infants younger than three months of age in Ethiopia.

L Muhe, M Tilahun, S Lulseged, S Kebede, D Enaro, S Ringertz, G Kronvall, S Gove, EK Mulholland

Journal article  |  1999  |  The Pediatric Infectious Disease Journal

METHODS: Within a multicenter study coordinated by WHO, an investigation of the etiologic agents of pneumonia, sepsis and meningit..

Etiology of serious infections in young Gambian infants.

EK Mulholland, OO Ogunlesi, RA Adegbola, M Weber, BE Sam, A Palmer, MJ Manary, O Secka, M Aidoo, D Hazlett, H Whittle, BM Greenwood

Journal article  |  1999  |  The Pediatric Infectious Disease Journal

BACKGROUND: Despite improvements in infant mortality rates in many developing countries including The Gambia, neonatal mortality r..

Risk factors for severe respiratory syncytial virus infection leading to hospital admission in children in the Western Region of The Gambia.

MW Weber, P Milligan, S Hilton, G Lahai, H Whittle, EK Mulholland, BM Greenwood

Journal article  |  1999  |  International Journal of Epidemiology

BACKGROUND: Acute lower respiratory tract infections (ALRI) are the major cause of mortality and morbidity in young children world..

An evaluation of the informed consent procedure used during a trial of a Haemophilus influenzae type B conjugate vaccine undertaken in The Gambia, West Africa.

A Leach, S Hilton, BM Greenwood, E Manneh, B Dibba, A Wilkins, EK Mulholland

Journal article  |  1999  |  Social Science & Medicine

It has recently been debated whether it is possible or desirable to have one internationally recognised standard of "informed cons..

Long-term morbidity and mortality following hypoxaemic lower respiratory tract infection in Gambian children.

TE West, T Goetghebuer, P Milligan, EK Mulholland, MW Weber

Journal article  |  1999  |  Bulletin of the World Health Organization

Acute lower respiratory infections (ALRI) are the main cause of death in young children worldwide. We report here the results of a..

Comparison of nasal prongs with nasal catheters in the delivery of oxygen to children with hypoxia.

L Muhe, H Degefu, B Worku, B Oljira, EK Mulholland

Journal article  |  1998  |  Journal of Tropical Pediatrics

Efficient, inexpensive, and safe methods of oxygen delivery are needed for children with severe pneumonia in developing countries...

The Gambian Haemophilus influenzae type b vaccine trial: what does it tell us about the burden of Haemophilus influenzae type b disease?

EK Mulholland, RA Adegbola

Conference Proceedings  |  1998  |  The Pediatric Infectious Disease Journal

The true burden of disease caused by Haemophilus influenzae type b (Hib) remains a mystery in many parts of the developing world. ..

Nutritional status of children admitted to hospital with different diseases and its relationship to outcome in The Gambia, West Africa.

WD Man, M Weber, A Palmer, G Schneider, R Wadda, S Jaffar, EK Mulholland, BM Greenwood

Journal article  |  1998  |  Tropical Medicine & International Health

Admission records from two paediatric units in The Gambia were used to explore the relationship between admission weight and diffe..

Pulse oximetry in developing countries.

MW Weber, EK Mulholland

Journal article  |  1998  |  The Lancet

Development of a clinical prediction model for an ordinal outcome: the World Health Organization Multicentre Study of Clinical Signs and Etiological agents of Pneumonia, Sepsis and Meningitis in Young Infants. WHO/ARI Young Infant Multicentre Study Group.

FE Harrell, PA Margolis, S Gove, KE Mason, EK Mulholland, D Lehmann, L Muhe, S Gatchalian, HF Eichenwald

Journal article  |  1998  |  Statistics in Medicine

This paper describes the methodologies used to develop a prediction model to assist health workers in developing countries in faci..

Respiratory syncytial virus infection in tropical and developing countries.

MW Weber, EK Mulholland, BM Greenwood

Journal article  |  1998  |  Tropical Medicine and International Health

Little is known about the epidemiology of respiratory syncytial virus (RSV) infection in tropical and developing countries; the da..

Autism, inflammatory bowel disease, and MMR vaccine.

D Black, H Prempeh, T Baxter

Journal article  |  1998  |  The Lancet

The clinical spectrum of respiratory syncytial virus disease in The Gambia.

MW Weber, R Dackour, S Usen, G Schneider, RA Adegbola, P Cane, S Jaffar, P Milligan, BM Greenwood, H Whittle, EK Mulholland

Journal article  |  1998  |  The Pediatric Infectious Disease Journal

BACKGROUND: Respiratory syncytial virus (RSV) is a well-recognized cause of lower respiratory tract infections in early childhood ..

Seroprevalence of antibodies to group B streptococcal polysaccharides in Gambian mothers and their newborns.

RO Suara, RA Adegbola, EK Mulholland, BM Greenwood, CJ Baker

Journal article  |  1998  |  Journal of the National Medical Association

In developing countries, little is known about the relationship between group B streptococcal (GBS) colonization in pregnant women..

Erratum: Nutritional status of children admitted to hospital with different diseases and its relationship to outcome in The Gambia, West Africa (Tropical Medicine and International Health (August 1998) 3:8 (678-686))

WDC Man, M Weber, A Palmer, G Schneider, R Wadda, S Jaffar, EK Mulholland, BM Greenwood

Journal article  |  1998  |  Tropical Medicine and International Health

Bacterial isolates from blood and lung aspirate cultures in Gambian children with lobar pneumonia.

AG Falade, EK Mulholland, RA Adegbola, BM Greenwood

Journal article  |  1997  |  Annals of Tropical Paediatrics

As part of a study of the aetiology of pneumonia in malnourished and well nourished children, 100 children aged between 3 and 58 m..

Oxygen administration to hypoxic children in Ethiopia: a randomized controlled study comparing complications in the use of nasal prongs with nasopharyngeal catheters.

L Muhe, H Degefu, B Worku, B Oljira, EK Mulholland

Journal article  |  1997  |  Annals of Tropical Paediatrics

Oxygen administration is one of the most important therapeutic interventions for a child with severe acute lower respiratory tract..

Data management for an efficacy trial of a vaccine in the Gambia.

GP Lahai, EK Mulholland, S Hilton, G Fegan, H Inskip, O Yuuni, JE Bangali, BM Greenwood

Journal article  |  1997  |  Methods of Information in Medicine

An individually randomised double-blind trial of PRP-T Hib conjugate vaccine was conducted in the Gambia between 1993 and 1995, in..

Predictors of hypoxaemia in hospital admissions with acute lower respiratory tract infection in a developing country

MW Weber, S Usen, A Palmer, S Jaffar, EK Mulholland

Journal article  |  1997  |  Archives of Disease in Childhood

Pallor as a clinical sign of severe anaemia in children: an investigation in the Gambia.

MW Weber, SD Kellingray, A Palmer, S Jaffar, EK Mulholland, BM Greenwood

Journal article  |  1997  |  Bulletin of the World Health Organization

Anaemia associated with malaria is a major public health problem in African countries. Since most primary health facilities have t..

Evaluation of an algorithm for the integrated management of childhood illness in an area with seasonal malaria in the Gambia.

MW Weber, EK Mulholland, S Jaffar, H Troedsson, S Gove, BM Greenwood

Journal article  |  1997  |  Bulletin of the World Health Organization

Most of the 12.4 million deaths occurring every year among under-5-year-olds in developing countries could be prevented by the app..

Humidification of oxygen with unheated humidifiers in tropical climates.

MW Weber, A Palmer, S Jaffar, EK Mulholland

Journal article  |  1996  |  Pediatric Pulmonology

In developing countries, oxygen therapy in hospitals is frequently humidified with unheated bubble-through humidifiers. We assesse..

Oxygen delivery: Nasopharyngeal catheter or nasal prongs?

F Shann

Journal article  |  1996  |  The Journal of Pediatrics

Prevalence of neutralizing antibody to respiratory syncytial virus in sera from mothers and newborns residing in the Gambia and in The United States.

RO Suara, PA Piedra, WP Glezen, RA Adegbola, M Weber, EK Mulholland, BM Greenwood, H Whittle

Journal article  |  1996  |  Clinical and Diagnostic Laboratory Immunology

The prevalence of maternal respiratory syncytial virus (RSV)-neutralizing antibodies has been documented in developed countries, b..

Haemophilus influenzae type b disease in the western region of The Gambia: background surveillance for a vaccine efficacy trial.

RA Adegbola, EK Mulholland, AG Falade, O Secka, R Sarge-Njai, T Corrah, A Palmer, G Schneider, BM Greenwood

Journal article  |  1996  |  Annals of Tropical Paediatrics

In preparation for a field trial of an Haemophilus influenzae type b conjugate vaccine in the Western Region of The Gambia, a 3-ye..

The use of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine mixed with diphtheria-tetanus-pertussis vaccine in Gambian infants.

EK Mulholland, A Hoestermann, JI Ward, N Maine, C Ethevenaux, BM Greenwood

Journal article  |  1996  |  Vaccine

In preparation for an efficacy trial of PRP-T Haemophilus influenzae type b conjugate vaccine, 251 Gambian infants were randomized..

A randomized trial of chloramphenicol vs. trimethoprim-sulfamethoxazole for the treatment of malnourished children with community-acquired pneumonia.

EK Mulholland, AG Falade, PT Corrah, C Omosigho, P N'Jai, B Giadom, RA Adegbola, H Tschäppeler, J Todd, BM Greenwood

Journal article  |  1995  |  The Pediatric Infectious Disease Journal

Children in developing countries who present with malnutrition often have infections, particularly pneumonia, at the time of prese..

Comparison of nasal prongs and nasopharyngeal catheter for the delivery of oxygen in children with hypoxemia because of a lower respiratory tract infection.

MW Weber, A Palmer, A Oparaugo, EK Mulholland

Journal article  |  1995  |  The Journal of Pediatrics

OBJECTIVE: To determine the best method of oxygen delivery for children in developing countries who have hypoxemia caused by acute..

Effect of azithromycin on pharyngeal microflora.

RA Adegbola, EK Mulholland, R Bailey, O Secka, T Sadiq, K Glasgow, D Mabey

Journal article  |  1995  |  The Pediatric Infectious Disease Journal

In reply

RA Adegbola, EK Mulholland, BM Greenwood

Journal article  |  1995  |  Pediatric Infectious Disease Journal

Use of simple clinical signs to predict pneumonia in young Gambian children: the influence of malnutrition.

AG Falade, H Tschäppeler, BM Greenwood, EK Mulholland

Journal article  |  1995  |  Bulletin of the World Health Organization

The current WHO recommendations for the case management of acute respiratory infections (ARI) in children aged 2 months to 5 years..

The etiology of pneumonia in malnourished and well-nourished Gambian children.

RA Adegbola, AG Falade, BE Sam, M Aidoo, I Baldeh, D Hazlett, H Whittle, BM Greenwood, EK Mulholland

Journal article  |  1994  |  The Pediatric Infectious Disease Journal

During a 2-year period 159 malnourished children ages 3 months to 5 years with radiologic evidence of pneumonia were investigated ..

Carriage of group B Streptococci in pregnant Gambian mothers and their infants.

RO Suara, RA Adegbola, CJ Baker, O Secka, EK Mulholland, BM Greenwood

Journal article  |  1994  |  Journal of Infectious Diseases

The prevalence of group B streptococcal (GBS) colonization was studied in 136 pregnant women and their newborn infants by collecti..

Haemophilus influenzae type b meningitis after three doses of vaccine.

EK Mulholland, A Hoestermann, RO Suara, RA Adegbola, G Siber, C Thompson, BM Greenwood

Journal article  |  1994  |  The Lancet

The immunogenicity and safety of Haemophilus influenzae type b-tetanus toxoid conjugate vaccine in Gambian infants.

EK Mulholland, P Byass, H Campbell, B Fritzell, AM Greenwood, J Todd, BM Greenwood

Journal article  |  1994  |  Annals of Tropical Paediatrics

In developing countries, Haemophilus influenzae type b is a major cause of meningitis and pneumonia in the 1st year of life. The s..

Safety and immunogenicity of Haemophilus influenzae type B-Neisseria meningitidis group B outer membrane protein complex conjugate vaccine mixed in the syringe with diphtheria-tetanus-pertussis vaccine in young Gambian infants.

EK Mulholland, VI Ahonkhai, AM Greenwood, LC Jonas, LJ Lukacs, CM Mink, JM Staub, J Todd, PP Vella, BM Greenwood

Journal article  |  1993  |  The Pediatric Infectious Disease Journal

To ensure compliance and to reduce costs it is important, especially in less developed countries, that programs of child immunizat..

Persistence of antibody at 18 months following vaccination of young Gambian infants with PRP-OMPC Haemophilus influenzae type b conjugate vaccine.

EK Mulholland, J Todd, M Rowe, H Campbell, P Byass, PP Vella, VI Ahonkhai, BM Greenwood

Journal article  |  1993  |  Annals of Tropical Paediatrics

The rate of decline in anti-PRP antibody levels was measured in two groups of Gambian children who had been given PRP-OMPC at 1 an..

Health screening of international adoptees. Evaluation of a hospital based clinic.

AJ Nicholson, BM Francis, EK Mulholland, AL Moulden, F Oberklaid

Conference Proceedings  |  1992  |  Medical Journal of Australia

OBJECTIVE: To report the findings of health screening of 100 international adoptees. DESIGN: Retrospective case review. SETTING AN..

Standardized diagnosis of pneumonia in developing countries.

EK Mulholland, EA Simoes, MO Costales, EJ McGrath, EM Manalac, S Gove

Journal article  |  1992  |  The Pediatric Infectious Disease Journal

The World Health Organization recommends the use of raised respiratory rate and chest wall indrawing to enable health workers in d..

WHO guidelines on detecting pneumonia in children.

Journal article  |  1991  |  The Lancet

Pertussis vaccine: a time-bomb?

EK Mulholland

Journal article  |  1990  |  The Lancet

CLINICAL FINDINGS AND SEVERITY OF ACUTE BRONCHIOLITIS

EK MULHOLLAND, A OLINSKY, FA SHANN

Journal article  |  1990  |  The Lancet

Childhood tuberculosis in Victoria, 1970-86.

EK Mulholland, GL Gilbert, RE Kempster

Journal article  |  1989  |  Journal of Paediatrics and Child Health

With the declining incidence of tuberculosis, childhood tuberculosis has become an uncommon disease in Australia. This study exami..