Annabell Bachem

Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

Marcel Doerflinger, Yexuan Deng, Paul Whitney, Ranja Salvamoser, Sven Engel, Andrew J Kueh, Lin Tai, Annabell Bachem, Elise Gressier, Niall D Geoghegan, Stephen Wilcox, Kelly L Rogers, Alexandra L Garnham, Michael A Dengler, Stefanie M Bader, Gregor Ebert, Jaclyn S Pearson, Dominic De Nardo, Nancy Wang, Chenying Yang, et al.

Journal article  |  2020  |  Immunity

Programmed cell death contributes to host defense against pathogens. To investigate the relative importance of pyroptosis, necropt..

Nuclear response to divergent mitochondrial DNA genotypes modulates the interferon immune response.

M Isabel G Lopez Sanchez, Mark Ziemann, Annabell Bachem, Rahul Makam, Jonathan G Crowston, Carl A Pinkert, Matthew McKenzie, Sammy Bedoui, Ian A Trounce

Journal article  |  2020  |  PLOS ONE

Mitochondrial OXPHOS generates most of the energy required for cellular function. OXPHOS biogenesis requires the coordinated expre..

Microbiota-Derived Short-Chain Fatty Acids Promote the Memory Potential of Antigen-Activated CD8( ) T Cells

Annabel Bachem, Christina Makhlouf, Katrina J Binger, David P de Souza, Deidra Tull, Katharina Hochheiser, Paul G Whitney, Daniel Fernandez-Ruiz, Sabrina Dahling, Wolfgang Kastemuller, Johanna Jonsson, Elise Gressier, Andrew M Lew, Carolina Perdomo, Andreas Kupz, William Figgett, Fabienne Mackay, Moshe Oleshansky, Brendan E Russ, Ian A Parish, et al.

Journal article  |  2019  |  Immunity

Interactions with the microbiota influence many aspects of immunity, including immune cell development, differentiation, and funct..

Effective Priming of Herpes Simplex Virus-Specific CD8( ) T Cells In Vivo Does Not Require Infected Dendritic Cells

Paul G Whitney, Christina Makhlouf, Beth MacLeod, Joel Z Ma, Elise Gressier, Marie Greyer, Katharina Hochheiser, Annabell Bachem, Ali Zaid, David Voehringer, William R Heath, Mayura V Wagle, Ian Parish, Tiffany A Russell, Stewart A Smith, David C Tscharke, Thomas Gebhardt, Sammy Bedoui

Journal article  |  2018  |  Journal of Virology

POSTTRANSLATIONAL MODIFICATION AS A CRITICAL DETERMINANT OF CYTOPLASMIC INNATE IMMUNE RECOGNITION

Paul J Baker, Dominic De Nardo, Fiona Moghaddas, Son Tran Le, Annabell Bachem, Nguyen Tan, Thomas Hayman, Hazel Tye, James E Vince, Sammy Bedoui, Richard L Ferrero, Seth L Masters

Journal article  |  2017  |  Physiological Reviews

Cooperation between Monocyte-Derived Cells and Lymphoid Cells in the Acute Response to a Bacterial Lung Pathogen

Andrew S Brown, Chao Yang, Ka Yee Fung, Annabell Bachem, Dorothee Bourges, Sammy Bedoui, Elizabeth L Hartland, Ian R van Driel

Journal article  |  2016  |  PLOS Pathogens

T Cell Help Amplifies Innate Signals in CD8( ) DCs for Optimal CD8( ) T Cell Priming

Marie Greyer, Paul G Whitney, Angus T Stock, Gayle M Davey, Christina Tebartz, Annabell Bachem, Justine D Mintern, Richard A Strugnell, Stephen J Turner, Thomas Gebhardt, Meredith O'Keeffe, William R Heath, Sammy Bedoui

Journal article  |  2016  |  Cell Reports

Induction of Potent CD8 T Cell Cytotoxicity by Specific Targeting of Antigen to Cross-Presenting Dendritic Cells In Vivo via Murine or Human XCR1

Evelyn Hartung, Martina Becker, Annabell Bachem, Nele Reeg, Anika Jaekel, Andreas Hutloff, Harald Weber, Christoph Weise, Claudia Giesecke, Volker Henn, Stephanie Gurka, Konstantinos Anastassiadis, Hans W Mages, Richard A Kroczek

Journal article  |  2015  |  The Journal of Immunology

Ontogenic, Phenotypic, and Functional Characterization of XCR1( ) Dendritic Cells Leads to a Consistent Classification of Intestinal Dendritic Cells Based on the Expression of XCR1 and SIRPα.

Martina Becker, Steffen Güttler, Annabell Bachem, Evelyn Hartung, Ahmed Mora, Anika Jäkel, Andreas Hutloff, Volker Henn, Hans Werner Mages, Stephanie Gurka, Richard A Kroczek

Journal article  |  2014  |  Frontiers in Immunology

In the past, lack of lineage markers confounded the classification of dendritic cells (DC) in the intestine and impeded a full und..

Expression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation

Annabell Bachem, Evelyn Hartung, Steffen Guettler, Ahmed Mora, Xuefei Zhou, Anika Hegemann, Maud Plantinga, Elisa Mazzini, Patrizia Stoitzner, Stephanie Gurka, Volker Henn, Hans W Mages, Richard A Kroczek

Journal article  |  2012  |  Frontiers in Immunology