Yi Ju is a Research Fellow in Nanostructured Interfaces and Materials Science Group (https://chemical.eng.unimelb.edu.au/nano/) in the Department of Chemical and Biomolecular Engineering at the University of Melbourne. His research interest includes particle engineering, bio-nano science, bio-imaging and diagnostics, drug and protein delivery.
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Yi Ju's selected work
Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modu..
Self-assembling influenza nanoparticle vaccines drive extended germinal center activity an..
Modulating the Selectivity and Stealth Properties of Ellipsoidal Polymersomes through a Mu..
Displaying the most recent project by Yi Ju.
Displaying the 41 most recent scholarly works by Yi Ju.
Template-Mediated Assembly of DNA into Microcapsules for Immunological Modulation.
Yijiao Qu, Yi Ju, Christina Cortez-Jugo, Zhixing Lin, Shiyao Li, Jiajing Zhou, Yutian Ma, Agata Glab, Stephen J Kent, Francesca Cavalieri, Frank Caruso
Journal article | 2020 | Small
There is a need for effective vaccine delivery systems and vaccine adjuvants without extraneous excipients that can compromise or ..
Polyphenol-Mediated Assembly for Particle Engineering.
Jiajing Zhou, Zhixing Lin, Yi Ju, Md Arifur Rahim, Joseph J Richardson, Frank Caruso
Journal article | 2020 | Accounts of Chemical Research
ConspectusPolyphenols are naturally occurring compounds that are ubiquitous in plants and display a spectrum of physical, chemical..
Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies
Zachary H Houston, Jens Bunt, Kok-Siong Chen, Simon Puttick, Christopher B Howard, Nicholas L Fletcher, Adrian V Fuchs, Jiwei Cui, Yi Ju, Gary Cowin, Xin Song, Andrew W Boyd, Stephen M Mahler, Linda J Richards, Frank Caruso, Kristofer J Thurecht
Journal article | 2020 | ACS Central Science
Increasing accumulation and retention of nanomedicines within tumor tissue is a significant challenge, particularly in the case of..
Self-assembling influenza nanoparticle vaccines drive extended germinal center activity and memory B cell maturation.
Hannah G Kelly, Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Yi Ju, Wenbo Jiang, Verena C Wimmer, Brigette C Duckworth, Joanna R Groom, Frank Caruso, Masaru Kanekiyo, Stephen J Kent, Adam K Wheatley
Journal article | 2020 | JCI Insight
Protein-based, self-assembling nanoparticles elicit superior immunity compared with soluble protein vaccines, but the immune mecha..
Modulating the Selectivity and Stealth Properties of Ellipsoidal Polymersomes through a Multivalent Peptide Ligand Display
Kristel C Tjandra, Chelsea R Forest, Chin Ken Wong, Sheilajen Alcantara, Hannah G Kelly, Yi Ju, Martina H Stenzel, Joshua A McCarroll, Maria Kavallaris, Frank Caruso, Stephen J Kent, Pall Thordarson
Journal article | 2020 | Advanced Healthcare Materials
There is a need for improved nanomaterials to simultaneously target cancer cells and avoid non‐specific clearance by phagocytes. A..
Engineering of Nebulized Metal-Phenolic Capsules for Controlled Pulmonary Deposition
Yi Ju, Christina Cortez-Jugo, Jingqu Chen, Ting-Yi Wang, Andrew J Mitchell, Evelyn Tsantikos, Nadja Bertleff-Zieschang, Yu-Wei Lin, Jiaying Song, Yizhe Cheng, Srinivas Mettu, Md Arifur Rahim, Shuaijun Pan, Gyeongwon Yun, Margaret L Hibbs, Leslie Y Yeo, Christoph E Hagemeyer, Frank Caruso
Journal article | 2020 | Advanced Science
Particle-based pulmonary delivery has great potential for delivering inhalable therapeutics for local or systemic applications. Th..
Self-Assembly of a Metal-Phenolic Sorbent for Broad-Spectrum Metal Sequestration
Md Arifur Rahim, Gan Lin, Pietro Pacchin Tomanin, Yi Ju, Anders Barlow, Mattias Bjornmalm, Frank Caruso
Journal article | 2020 | ACS Applied Materials & Interfaces
Metal contamination of water bodies from industrial effluents presents a global threat to the aquatic ecosystem. To address this c..
Modular Assembly of Host-Guest Metal-Phenolic Networks Using Macrocyclic Building Blocks
Shuaijun Pan, Rui Guo, Nadja Bertleff-Zieschang, Shanshan Li, Quinn A Besford, Qi-Zhi Zhong, Gyeongwon Yun, Yunti Zhang, Francesca Cavalieri, Yi Ju, Eirini Goudeli, Joseph J Richardson, Frank Caruso
Journal article | 2020 | Angewandte Chemie International Edition
The manipulation of interfacial properties has broad implications for the development of high‐performance coatings. Metal–phenolic..
Expanding the Toolbox of Metal-Phenolic Networks via Enzyme-Mediated Assembly
Qi-Zhi Zhong, Joseph J Richardson, Shiyao Li, Wenjie Zhang, Yi Ju, Jianhua Li, Shuaijun Pan, Jingqu Chen, Frank Caruso
Journal article | 2020 | Angewandte Chemie International Edition
Functional coatings are of considerable interest because of their fundamental implications for interfacial assembly and promise fo..
Metal-Phenolic Coatings as a Platform to Trigger Endosomal Escape of Nanoparticles.
Jingqu Chen, Jianhua Li, Jiajing Zhou, Zhixing Lin, Francesca Cavalieri, Ewa Czuba-Wojnilowicz, Yingjie Hu, Agata Glab, Yi Ju, Joseph J Richardson, Frank Caruso
Journal article | 2019 | ACS Nano
The intracellular delivery of functional nanoparticles (NPs) and the release of therapeutic payloads at a target site are central ..
Cellular Targeting of Bispecific Antibody-Functionalized Poly(ethylene glycol) Capsules: Do Shape and Size Matter?
Danzi Song, Jiwei Cui, Yi Ju, Matthew Faria, Huanli Sun, Christopher B Howard, Kristofer J Thurecht, Frank Caruso
Journal article | 2019 | ACS Appl Mater Interfaces
In the present study, a capsule system that consists of a stealth carrier based on poly(ethylene glycol) (PEG) and functionalized ..
SupraCells: Living Mammalian Cells Protected within Functional Modular Nanoparticle-Based Exoskeletons
Wei Zhu, Jimin Guo, Shahrouz Amini, Yi Ju, Jacob Ongudi Agola, Andreas Zimpel, Jin Shang, Achraf Noureddine, Frank Caruso, Stefan Wuttke, Jonas G Croissant, C Jeffrey Brinker
Journal article | 2019 | ADVANCED MATERIALS
Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies
Jiwei Cui, Yi Ju, Zachary H Houston, Joshua J Class, Nicholas L Fletcher, Sheilajen Alcantara, Qiong Dai, Christopher B Howard, Stephen M Mahler, Adam K Wheatley, Robert De Rose, Paul T Brannon, Brett M Paterson, Paul S Donnelly, Kristoferj Thurecht, Frank Caruso, Stephen J Kent
Journal article | 2019 | ADVANCED HEALTHCARE MATERIALS
Modular Metal-Organic Polyhedra Superassembly: From Molecular-Level Design to Targeted Drug Delivery
Wei Zhu, Jimin Guo, Yi Ju, Rita E Serda, Jonas G Croissant, Jin Shang, Eric Coker, Jacob Ongudi Agola, Qi-Zhi Zhong, Yuan Ping, Frank Caruso, C Jeffrey Brinker
Journal article | 2019 | Advanced Materials
Targeted drug delivery remains at the forefront of biomedical research but remains a challenge to date. Herein, the first superass..
Metal-dependent inhibition of amyloid fibril formation: synergistic effects of cobalt-tannic acid networks
Wenjie Zhang, Andrew J Christofferson, Quinn A Besford, Joseph J Richardson, Junling Guo, Yi Ju, Kristian Kempe, Irene Yarovsky, Frank Caruso
Journal article | 2019 | NANOSCALE
Metal–phenolic networks (MPNs) have received widespread interest owing to their modular incorporation of functional metal ions and..
Quantitative Measurement of Cell-Nanoparticle Interactions Using Mass Cytometry.
Andrew J Mitchell, Angela Ivask, Yi Ju
Book Chapter | 2019 | Methods in Molecular Biology
Mass cytometry is a technique that uses inductively coupled plasma mass spectrometry (ICP-MS) to quantify the isotopic composition..
Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake.
Jiwei Cui, Karen Alt, Yi Ju, Sylvia T Gunawan, Julia A Braunger, Ting-Yi Wang, Yunlu Dai, Qiong Dai, Joseph J Richardson, Junling Guo, Mattias Björnmalm, Christoph E Hagemeyer, Frank Caruso
Journal article | 2019 | Biomacromolecules
Drug carriers typically require both stealth and targeting properties to minimize nonspecific interactions with healthy cells and ..
Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug Delivery
Yutian Ma, Mattias Bjoernmalm, Andrew K Wise, Christina Cortez-Jugo, Eve Revalor, Yi Ju, Orlagh M Feeney, Rachael T Richardson, Eric Hanssen, Robert K Shepherd, Christopher JH Porter, Frank Caruso
Journal article | 2018 | ACS APPLIED MATERIALS & INTERFACES
Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging
Thomas Bonnard, Anand Jayapadman, Jasmine A Putri, Jiwei Cui, Yi Ju, Catherine Carmichael, Thomas A Angelovich, Stephen H Cody, Shauna French, Karline Pascaud, Hannah A Pearce, Shweta Jagdale, Frank Caruso, Christoph E Hagemeyer
Journal article | 2018 | ACS NANO
Engineered Hydrogen-Bonded Glycopolymer Capsules and Their Interactions with Antigen Presenting Cells
Kristian Kempe, Sue D Xiang, Paul Wilson, Md Arifur Rahim, Yi Ju, Michael R Whittaker, David M Haddleton, Magdalena Plebanski, Frank Caruso, Thomas P Davis
Journal article | 2017 | ACS APPLIED MATERIALS & INTERFACES
Modular assembly of superstructures from polyphenol-functionalized building blocks
Junling Guo, Blaise L Tardy, Andrew J Christofferson, Yunlu Dai, Joseph J Richardson, Wei Zhu, Ming Hu, Yi Ju, Jiwei Cui, Raymond R Dagastine, Irene Yarovsky, Frank Caruso
Journal article | 2016 | NATURE NANOTECHNOLOGY
Surface-Confined Amorphous Films from Metal-Coordinated Simple Phenolic Ligands
Md Arifur Rahim, Kristian Kempe, Markus Muellner, Hirotaka Ejima, Yi Ju, Martin P van Koeverden, Tomoya Suma, Julia A Braunger, Michael G Leeming, Brendan F Abrahams, Frank Caruso
Journal article | 2015 | CHEMISTRY OF MATERIALS
Honours, Awards and Fellowships
Awarded the 2017 Reviewer Excellence Award from Chemistry of Materials for the outstanding contribution as a reviewer (top 1% reviewers).
Best Tutor Award
Best Biomedical Engineering Project
Research Fellow In Nanoengineered Materials
Doctor of Philosophy
University of Melbourne
Master of Engineering (Biomedical) with Distinction
University of Melbourne
Bachelor of Bioengineering
Tianjin University of Technology