Yi Ju

Template-Mediated Assembly of DNA into Microcapsules for Immunological Modulation.

Yijiao Qu, Yi Ju, Christina Cortez-Jugo, Zhixing Lin, Shiyao Li, Jiajing Zhou, Yutian Ma, Agata Glab, Stephen J Kent, Francesca Cavalieri, Frank Caruso

Journal article  |  2020  |  Small

There is a need for effective vaccine delivery systems and vaccine adjuvants without extraneous excipients that can compromise or ..

Polyphenol-Mediated Assembly for Particle Engineering.

Jiajing Zhou, Zhixing Lin, Yi Ju, Md Arifur Rahim, Joseph J Richardson, Frank Caruso

Journal article  |  2020  |  Accounts of Chemical Research

ConspectusPolyphenols are naturally occurring compounds that are ubiquitous in plants and display a spectrum of physical, chemical..

Understanding the Uptake of Nanomedicines at Different Stages of Brain Cancer Using a Modular Nanocarrier Platform and Precision Bispecific Antibodies

Zachary H Houston, Jens Bunt, Kok-Siong Chen, Simon Puttick, Christopher B Howard, Nicholas L Fletcher, Adrian V Fuchs, Jiwei Cui, Yi Ju, Gary Cowin, Xin Song, Andrew W Boyd, Stephen M Mahler, Linda J Richards, Frank Caruso, Kristofer J Thurecht

Journal article  |  2020  |  ACS Central Science

Increasing accumulation and retention of nanomedicines within tumor tissue is a significant challenge, particularly in the case of..

Self-assembling influenza nanoparticle vaccines drive extended germinal center activity and memory B cell maturation.

Hannah G Kelly, Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Yi Ju, Wenbo Jiang, Verena C Wimmer, Brigette C Duckworth, Joanna R Groom, Frank Caruso, Masaru Kanekiyo, Stephen J Kent, Adam K Wheatley

Journal article  |  2020  |  JCI Insight

Protein-based, self-assembling nanoparticles elicit superior immunity compared with soluble protein vaccines, but the immune mecha..

Modulating the Selectivity and Stealth Properties of Ellipsoidal Polymersomes through a Multivalent Peptide Ligand Display

Kristel C Tjandra, Chelsea R Forest, Chin Ken Wong, Sheilajen Alcantara, Hannah G Kelly, Yi Ju, Martina H Stenzel, Joshua A McCarroll, Maria Kavallaris, Frank Caruso, Stephen J Kent, Pall Thordarson

Journal article  |  2020  |  Advanced Healthcare Materials

There is a need for improved nanomaterials to simultaneously target cancer cells and avoid non‐specific clearance by phagocytes. A..

Engineering of Nebulized Metal-Phenolic Capsules for Controlled Pulmonary Deposition

Yi Ju, Christina Cortez-Jugo, Jingqu Chen, Ting-Yi Wang, Andrew J Mitchell, Evelyn Tsantikos, Nadja Bertleff-Zieschang, Yu-Wei Lin, Jiaying Song, Yizhe Cheng, Srinivas Mettu, Md Arifur Rahim, Shuaijun Pan, Gyeongwon Yun, Margaret L Hibbs, Leslie Y Yeo, Christoph E Hagemeyer, Frank Caruso

Journal article  |  2020  |  Advanced Science

Particle-based pulmonary delivery has great potential for delivering inhalable therapeutics for local or systemic applications. Th..

Self-Assembly of a Metal-Phenolic Sorbent for Broad-Spectrum Metal Sequestration

Md Arifur Rahim, Gan Lin, Pietro Pacchin Tomanin, Yi Ju, Anders Barlow, Mattias Bjornmalm, Frank Caruso

Journal article  |  2020  |  ACS Applied Materials & Interfaces

Metal contamination of water bodies from industrial effluents presents a global threat to the aquatic ecosystem. To address this c..

Modular Assembly of Host-Guest Metal-Phenolic Networks Using Macrocyclic Building Blocks

Shuaijun Pan, Rui Guo, Nadja Bertleff-Zieschang, Shanshan Li, Quinn A Besford, Qi-Zhi Zhong, Gyeongwon Yun, Yunti Zhang, Francesca Cavalieri, Yi Ju, Eirini Goudeli, Joseph J Richardson, Frank Caruso

Journal article  |  2020  |  Angewandte Chemie International Edition

The manipulation of interfacial properties has broad implications for the development of high‐performance coatings. Metal–phenolic..

Expanding the Toolbox of Metal-Phenolic Networks via Enzyme-Mediated Assembly

Qi-Zhi Zhong, Joseph J Richardson, Shiyao Li, Wenjie Zhang, Yi Ju, Jianhua Li, Shuaijun Pan, Jingqu Chen, Frank Caruso

Journal article  |  2020  |  Angewandte Chemie International Edition

Functional coatings are of considerable interest because of their fundamental implications for interfacial assembly and promise fo..

Metal-Phenolic Coatings as a Platform to Trigger Endosomal Escape of Nanoparticles.

Jingqu Chen, Jianhua Li, Jiajing Zhou, Zhixing Lin, Francesca Cavalieri, Ewa Czuba-Wojnilowicz, Yingjie Hu, Agata Glab, Yi Ju, Joseph J Richardson, Frank Caruso

Journal article  |  2019  |  ACS Nano

The intracellular delivery of functional nanoparticles (NPs) and the release of therapeutic payloads at a target site are central ..

Cellular Targeting of Bispecific Antibody-Functionalized Poly(ethylene glycol) Capsules: Do Shape and Size Matter?

Danzi Song, Jiwei Cui, Yi Ju, Matthew Faria, Huanli Sun, Christopher B Howard, Kristofer J Thurecht, Frank Caruso

Journal article  |  2019  |  ACS Appl Mater Interfaces

In the present study, a capsule system that consists of a stealth carrier based on poly(ethylene glycol) (PEG) and functionalized ..

SupraCells: Living Mammalian Cells Protected within Functional Modular Nanoparticle-Based Exoskeletons

Wei Zhu, Jimin Guo, Shahrouz Amini, Yi Ju, Jacob Ongudi Agola, Andreas Zimpel, Jin Shang, Achraf Noureddine, Frank Caruso, Stefan Wuttke, Jonas G Croissant, C Jeffrey Brinker

Journal article  |  2019  |  ADVANCED MATERIALS

Selective Metal-Phenolic Assembly from Complex Multicomponent Mixtures

Gan Lin, Md Arifur Rahim, Michael G Leeming, Christina Cortez-Jugo, Quinn A Besford, Yi Ju, Qi-Zhi Zhong, Stuart T Johnston, Jiajing Zhou, Frank Caruso

Journal article  |  2019  |  ACS APPLIED MATERIALS & INTERFACES

Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies

Jiwei Cui, Yi Ju, Zachary H Houston, Joshua J Class, Nicholas L Fletcher, Sheilajen Alcantara, Qiong Dai, Christopher B Howard, Stephen M Mahler, Adam K Wheatley, Robert De Rose, Paul T Brannon, Brett M Paterson, Paul S Donnelly, Kristoferj Thurecht, Frank Caruso, Stephen J Kent

Journal article  |  2019  |  ADVANCED HEALTHCARE MATERIALS

Nanoengineering of poly(ethylene glycol) particles for stealth and targeting

Frank Caruso

Journal article  |  2019  |  ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY

Modular Metal-Organic Polyhedra Superassembly: From Molecular-Level Design to Targeted Drug Delivery

Wei Zhu, Jimin Guo, Yi Ju, Rita E Serda, Jonas G Croissant, Jin Shang, Eric Coker, Jacob Ongudi Agola, Qi-Zhi Zhong, Yuan Ping, Frank Caruso, C Jeffrey Brinker

Journal article  |  2019  |  Advanced Materials

Targeted drug delivery remains at the forefront of biomedical research but remains a challenge to date. Herein, the first superass..

Metal-dependent inhibition of amyloid fibril formation: synergistic effects of cobalt-tannic acid networks

Wenjie Zhang, Andrew J Christofferson, Quinn A Besford, Joseph J Richardson, Junling Guo, Yi Ju, Kristian Kempe, Irene Yarovsky, Frank Caruso

Journal article  |  2019  |  NANOSCALE

Metal–phenolic networks (MPNs) have received widespread interest owing to their modular incorporation of functional metal ions and..

Quantitative Measurement of Cell-Nanoparticle Interactions Using Mass Cytometry.

Andrew J Mitchell, Angela Ivask, Yi Ju

Book Chapter  |  2019  |  Methods in Molecular Biology

Mass cytometry is a technique that uses inductively coupled plasma mass spectrometry (ICP-MS) to quantify the isotopic composition..

Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake.

Jiwei Cui, Karen Alt, Yi Ju, Sylvia T Gunawan, Julia A Braunger, Ting-Yi Wang, Yunlu Dai, Qiong Dai, Joseph J Richardson, Junling Guo, Mattias Björnmalm, Christoph E Hagemeyer, Frank Caruso

Journal article  |  2019  |  Biomacromolecules

Drug carriers typically require both stealth and targeting properties to minimize nonspecific interactions with healthy cells and ..

Spray Assembly of Metal-Phenolic Networks: Formation, Growth, and Applications

Qi-Zhi Zhong, Shuaijun Pan, Md Arifur Rahim, Gyeongwon Yun, Jianhua Li, Yi Ju, Zhixing Lin, Yiyuan Han, Yutian Ma, Joseph J Richardson, Frank Caruso

Journal article  |  2018  |  ACS APPLIED MATERIALS & INTERFACES

Self-Assembled Metal-Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles

Quinn A Besford, Yi Ju, Ting-Yi Wang, Gyeongwon Yun, PavelV Cherepanov, Christoph E Hagemeyer, Francesca Cavalieri, Frank Caruso

Journal article  |  2018  |  SMALL

Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug Delivery

Yutian Ma, Mattias Bjoernmalm, Andrew K Wise, Christina Cortez-Jugo, Eve Revalor, Yi Ju, Orlagh M Feeney, Rachael T Richardson, Eric Hanssen, Robert K Shepherd, Christopher JH Porter, Frank Caruso

Journal article  |  2018  |  ACS APPLIED MATERIALS & INTERFACES

Nanoengineering of Poly(ethylene glycol) Particles for Stealth and Targeting

Jiwei Cui, Mattias Bjornmalm, Yi Ju, Frank Caruso

Journal article  |  2018  |  LANGMUIR

Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging

Thomas Bonnard, Anand Jayapadman, Jasmine A Putri, Jiwei Cui, Yi Ju, Catherine Carmichael, Thomas A Angelovich, Stephen H Cody, Shauna French, Karline Pascaud, Hannah A Pearce, Shweta Jagdale, Frank Caruso, Christoph E Hagemeyer

Journal article  |  2018  |  ACS NANO

Supramolecular Metal-Phenolic Gels for the Crystallization of Active Pharmaceutical Ingredients

Md Arifur Rahim, Yuuki Hata, Mattias Bjornmalm, Yi Ju, Frank Caruso

Journal article  |  2018  |  SMALL

Multiligand Metal-Phenolic Assembly from Green Tea Infusions

Md Arifur Rahim, Mattias Bjornmalm, Nadja Bertleff-Zieschang, Yi Ju, Srinivas Mettu, Michael G Leeming, Frank Caruso

Journal article  |  2018  |  ACS APPLIED MATERIALS & INTERFACES

Acid-sensitive poly(beta-cyclodextrin)-based multifunctional supramolecular gene vector

Yunti Zhang, Qimin Jiang, Marcin Wojnilowicz, Shuaijun Pan, Yi Ju, Wenjie Zhang, Jia Liu, Renxi Zhuo, Xulin Jiang

Journal article  |  2018  |  Polymer Chemistry

Self-Assembled Nanoparticles from Phenolic Derivatives for Cancer Therapy

Yunlu Dai, Junling Guo, Ting-Yi Wang, Yi Ju, Andrew J Mitchell, Thomas Bonnard, Jiwei Cui, Joseph J Richardson, Christoph E Hagemeyer, Karen Alt, Frank Caruso

Journal article  |  2017  |  ADVANCED HEALTHCARE MATERIALS

An Enzyme-Coated Metal-Organic Framework Shell for Synthetically Adaptive Cell Survival

Kang Liang, Joseph J Richardson, Christian J Doonan, Xavier Mulet, Yi Ju, Jiwei Cui, Frank Caruso, Paolo Falcaro

Journal article  |  2017  |  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tuning the Properties of Polymer Capsules for Cellular Interactions

Huanli Sun, Jiwei Cui, Yi Ju, Xi Chen, Edgar HH Wong, Jenny Tran, Greg G Qiao, Frank Caruso

Journal article  |  2017  |  BIOCONJUGATE CHEMISTRY

Modulated Fragmentation of Proapoptotic Peptide Nanoparticles Regulates Cytotoxicity

Tomoya Suma, Jiwei Cui, Markus Muellner, Shiwei Fu, Jenny Tran, Ka Fung Noi, Yi Ju, Frank Caruso

Journal article  |  2017  |  JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineered Hydrogen-Bonded Glycopolymer Capsules and Their Interactions with Antigen Presenting Cells

Kristian Kempe, Sue D Xiang, Paul Wilson, Md Arifur Rahim, Yi Ju, Michael R Whittaker, David M Haddleton, Magdalena Plebanski, Frank Caruso, Thomas P Davis

Journal article  |  2017  |  ACS APPLIED MATERIALS & INTERFACES

Biofunctional metal-phenolic films from dietary flavonoids

Nadja Bertleff-Zieschang, Md Arifur Rahim, Yi Ju, Julia A Braunger, Tomoya Suma, Yunlu Dai, Shuaijun Pan, Francesca Cavalieri, Frank Caruso

Journal article  |  2017  |  CHEMICAL COMMUNICATIONS

Modular assembly of superstructures from polyphenol-functionalized building blocks

Junling Guo, Blaise L Tardy, Andrew J Christofferson, Yunlu Dai, Joseph J Richardson, Wei Zhu, Ming Hu, Yi Ju, Jiwei Cui, Raymond R Dagastine, Irene Yarovsky, Frank Caruso

Journal article  |  2016  |  NATURE NANOTECHNOLOGY

Metal-Phenolic Supramolecular Gelation

Md Arifur Rahim, Mattias Björnmalm, Tomoya Suma, Matthew Faria, Yi Ju, Kristian Kempe, Markus Müllner, Hirotaka Ejima, Anthony D Stickland, Frank Caruso

Journal article  |  2016  |  Angewandte Chemie

Metal-Phenolic Supramolecular Gelation

Md Arifur Rahim, Mattias Bjornmalm, Tomoya Suma, Matthew Faria, Yi Ju, Kristian Kempe, Markus Muellner, Hirotaka Ejima, Anthony D Stickland, Frank Caruso

Journal article  |  2016  |  ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Void Engineering in Metal-Organic Frameworks via Synergistic Etching and Surface Functionalization

Ming Hu, Yi Ju, Kang Liang, Tomoya Suma, Jiwei Cui, Frank Caruso

Journal article  |  2016  |  ADVANCED FUNCTIONAL MATERIALS

Engineered Metal-Phenolic Capsules Show Tunable Targeted Delivery to Cancer Cells

Yi Ju, Jiwei Cui, Huanli Sun, Markus Mullner, Yunlu Dai, Junling Guo, Nadja Bertleff-Zieschang, Tomoya Suma, Joseph J Richardson, Frank Caruso

Journal article  |  2016  |  BIOMACROMOLECULES

Surface-Confined Amorphous Films from Metal-Coordinated Simple Phenolic Ligands

Md Arifur Rahim, Kristian Kempe, Markus Muellner, Hirotaka Ejima, Yi Ju, Martin P van Koeverden, Tomoya Suma, Julia A Braunger, Michael G Leeming, Brendan F Abrahams, Frank Caruso

Journal article  |  2015  |  CHEMISTRY OF MATERIALS

Engineering Low-Fouling and pH-Degradable Capsules through the Assembly of Metal-Phenolic Networks

Yi Ju, Jiwei Cui, Markus Muellner, Tomoya Suma, Ming Hu, Frank Caruso

Journal article  |  2015  |  BIOMACROMOLECULES

Generalizable Strategy for Engineering Protein Particles with pH-Triggered Disassembly and Recoverable Protein Functionality

Tomoya Suma, Jiwei Cui, Markus Muellner, Yi Ju, Junling Guo, Ming Hu, Frank Caruso

Journal article  |  2015  |  ACS MACRO LETTERS