Kirsten Fairfax

The role of BAFF in the biology of NK cells

PS Quah, K Fairfax, D Andrews, F Mackay

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans

Jarny Choi, Tracey M Baldwin, Mae Wong, Jessica E Bolden, Kirsten A Fairfax, Erin C Lucas, Rebecca Cole, Christine Biben, Clare Morgan, Kerry A Ramsay, Ashley P Ng, Maria Kauppi, Lynn M Corcoran, Wei Shi, Nick Wilson, Michael J Wilson, Warren S Alexander, Douglas J Hilton, Carolyn A de Graaf

Journal article  |  2019  |  NUCLEIC ACIDS RESEARCH

Fluorescent antibiotics, vomocytosis, vaccine candidates and the inflammasome

Rachel J Lundie, Karla J Helbig, Jaclyn S Pearson, Kirsten A Fairfax

Journal article  |  2019  |  Clinical & Translational Immunology

This article summarises recent advances reported at the 9th Lorne Infection and Immunity Conference. This exciting conference host..

Identification of a Siglec-F plus granulocyte-macrophage progenitor

Jessica E Bolden, Erin C Lucas, Geyu Zhou, Jeremy A O'Sullivan, Carolyn A de Graaf, Mark D McKenzie, Ladina Di Rago, Tracey M Baldwin, Jake Shortt, Warren S Alexander, Bruce S Bochner, Matthew E Ritchie, Douglas J Hilton, Kirsten A Fairfax

Journal article  |  2018  |  Journal of Leukocyte Biology

Transcriptional profiling of eosinophil subsets in interleukin-5 transgenic mice

Kirsten A Fairfax, Jessica E Bolden, Aaron J Robinson, Erin C Lucas, Tracey M Baldwin, Kerry A Ramsay, Rebecca Cole, Douglas J Hilton, Carolyn A de Graaf

Journal article  |  2018  |  Journal of Leukocyte Biology

Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer

Jing Liu, Stephen J Blake, Heidi Harjunpaa, Kirsten A Fairfax, Michelle CR Yong, Stacey Allen, Holbrook E Kohrt, Kazuyoshi Takeda, Mark J Smyth, Michele WL Teng

Journal article  |  2016  |  Cancer Research

Haemopedia: An Expression Atlas of Murine Hematopoietic Cells

Carolyn A De Graaf, Jarny Choi, Tracey M Baldwin, Jessica E Bolden, Kirsten A Fairfax, Aaron J Robinson, Christine Biben, Clare Morgan, Kerry Ramsay, Ashley P Ng, Maria Kauppi, Elizabeth A Kruse, Tobias J Sargeant, Nick Seidenman, Angela D'Amico, Marthe C D'Ombrain, Erin C Lucas, Sandra Koernig, Adriana Baz Morelli, Michael J Wilson, et al.

Journal article  |  2016  |  STEM CELL REPORTS

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia

Margherita Ghisi, Lev Kats, Frederick Masson, Jason Li, Tobias Kratina, Eva Vidacs, Omer Gilan, Maria A Doyle, Andrea Newbold, Jessica E Bolden, Kirsten A Fairfax, Carolyn A de Graaf, Matthew Firth, Johannes Zuber, Ross A Dickins, Lynn M Corcoran, Mark A Dawson, Gabrielle T Belz, Ricky W Johnstone

Journal article  |  2016  |  Cancer Cell

NF kappa B1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

Elisha de Valle, George Grigoriadis, Lorraine A O'Reilly, Simon N Willis, Mhairi J Maxwell, Lynn M Corcoran, Evelyn Tsantikos, Jasper KS Cornish, Kirsten A Fairfax, Ajithkumar Vasanthakumar, Mark A Febbraio, Margaret L Hibbs, Marc Pellegrini, Ashish Banerjee, Philip D Hodgkin, Axel Kallies, Fabienne Mackay, Andreas Strasser, Steve Gerondakis, Raffi Gugasyan

Journal article  |  2016  |  Journal of Experimental Medicine

BAFF-driven autoimmunity requires CD19 expression

Kirsten A Fairfax, Evelyn Tsantikos, William A Figgett, Fabien B Vincent, Pin Shie Quah, Melanie LePage, Margaret L Hibbs, Fabienne Mackay

Journal article  |  2015  |  Journal of Autoimmunity

Deleting the BAFF receptor TACI protects against systemic lupus erythematosus without extensive reduction of B cell numbers

William A Figgett, Devy Deliyanti, Kirsten A Fairfax, Pin Shie Quah, Jennifer L Wilkinson-Berka, Fabienne Mackay

Journal article  |  2015  |  Journal of Autoimmunity

The RNA-binding protein HuR is essential for the B cell antibody response

Manuel D Diaz-Munoz, Sarah E Bell, Kirsten Fairfax, Elisa Monzon-Casanova, Adam F Cunningham, Mar Gonzalez-Porta, Simon R Andrews, Victoria I Bunik, Kathi Zarnack, Tomaz Curk, Ward A Heggermont, Stephane Heymans, Gary E Gibson, Dimitris L Kontoyiannis, Jernej Ule, Martin Turner

Journal article  |  2015  |  Nature Immunology

IL-10 regulates Aicda expression through miR-155

Kirsten A Fairfax, Michael P Gantier, Fabienne Mackay, Bryan RG Williams, Claire E McCoy

Journal article  |  2015  |  Journal of Leukocyte Biology

CD19 differentially regulates BCR signalling through the recruitment of PI3K

Yuekang Xu, Kirsten Fairfax, Amanda Light, Nicholas D Huntington, David M Tarlinton

Journal article  |  2014  |  Autoimmunity

The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice

Simona Infantino, Sarah A Jones, Jennifer A Walker, Mhairi J Maxwell, Amanda Light, Kristy O'Donnell, Evelyn Tsantikos, Victor Peperzak, Toby Phesse, Matthias Ernst, Fabienne Mackay, Margaret L Hibbs, Kirsten A Fairfax, David M Tarlinton

Journal article  |  2014  |  Science Signaling

Gene Therapy Delivery of Myelin Oligodendrocyte Glycoprotein (MOG) via Hematopoietic Stem Cell Transfer Induces MOG-Specific B Cell Deletion

Jie-Yu Chung, William Figgett, Kirsten Fairfax, Claude Bernard, James Chan, Ban-Hock Toh, Fabienne Mackay, Frank Alderuccio

Journal article  |  2014  |  The Journal of Immunology

The BAFF/APRIL system: Emerging functions beyond B cell biology and autoimmunity

Fabien B Vincent, Damien Saulep-Easton, William A Figgett, Kirsten A Fairfax, Fabienne Mackay

Journal article  |  2013  |  Cytokine & Growth Factor Reviews

Mcl-1 is essential for the survival of plasma cells

Victor Peperzak, Ingela Vikstroem, Jennifer Walker, Stefan P Glaser, Melanie LePage, Christine M Coquery, Loren D Erickson, Kirsten Fairfax, Fabienne Mackay, Andreas Strasser, Stephen L Nutt, David M Tarlinton

Journal article  |  2013  |  Nature Immunology

BAFF/BLyS inhibitors: A new prospect for treatment of systemic lupus erythematosus

Kirsten Fairfax, Ian R Mackay, Fabienne Mackay

Journal article  |  2012  |  IUBMB Life

Targeting malignant B cells as antigen-presenting cells: TLR-9 agonist induces systemic regression of lymphoma

N Klein-González, U Holtick, K Fairfax, MR Weihrauch, MS Von Bergwelt-Baildon

Journal article  |  2011  |  Expert Review of Vaccines

Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development

PN Kelly, MJ White, MW Goschnick, KA Fairfax, DM Tarlinton, SA Kinkel, P Bouillet, JM Adams, BT Kile, A Strasser

Journal article  |  2010  |  Cell Death & Differentiation

Signaling pathways in T follicular helper cells.

Julia Rolf, Kirsten Fairfax, Martin Turner

Journal article  |  2010  |  The Journal of Immunology

Th cell functional subsets have unique transcriptional programs that form the molecular basis for T cell differentiation and funct..

Plasma cell development: From B-cell subsets to long-term survival niches

Kirsten A Fairfax, Axel Kallies, Stephen L Nutt, David M Tarlinton

Journal article  |  2008  |  Seminars in Immunology

BLIMP1 guides the fate of effector B and T cells

Stephen L Nutt, Kirsten A Fairfax, Axel Kallies

Journal article  |  2007  |  Nat. Rev. Immunol.

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1

Axel Kallies, Jhagvaral Hasbold, Kirsten Fairfax, Clare Pridans, Dianne Emslie, Brent S McKenzie, Andrew M Lew, Lynn M Corcoran, Philip D Hodgkin, David M Tarlinton, Stephen L Nutt

Journal article  |  2007  |  Immunity

NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation

Nicholas D Huntington, Hy Tabarias, Kirsten Fairfax, Jason Brady, Yoshihiro Hayakawa, Mariapia A Degli-Esposti, Mark J Smyth, David M Tarlinton, Stephen L Nutt

Journal article  |  2007  |  The Journal of Immunology

Different kinetics of Blimp-1 induction in B cell subsets revealed by reporter gene

Kirsten A Fairfax, Lynn M Corcoran, Clare Pridans, Nicholas D Huntington, Axel Kallies, Stephen L Nutt, David M Tarlinton

Journal article  |  2007  |  J. Immunol.

Fc gamma RIIb controls bone marrow plasma cell persistence and apoptosis

Zou Xiang, Antony J Cutler, Rebecca J Brownlie, Kirsten Fairfax, Kate E Lawlor, Eva Severinson, Elizabeth U Walker, Rudolf A Manz, David M Tarlinton, Kenneth GC Smith

Journal article  |  2007  |  Nature Immunology