Vicki Lewis

PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity

Simote T Foliaki, Victoria Lewis, Abu MT Islam, Matteo Senesi, David Finkelstein, Laura J Ellett, Victoria A Lawson, Paul A Adlard, Blaine R Roberts, Steven J Collins

Journal article  |  2020  |  Biophysical Journal

Prion diseases are neurodegenerative disorders pathogenically linked to cellular prion protein (PrPC) misfolding into abnormal con..

The cellular prion protein beyond prion diseases.

Giorgia Manni, Victoria Lewis, Matteo Senesi, Giovanni Spagnolli, Francesca Fallarino, Steven J Collins, Sophie Mouillet-Richard, Emiliano Biasini

Journal article  |  2020  |  Swiss Medical Weekly

The cellular prion protein (PrPC), a cell surface glycoprotein originally identified for its central role in prion diseases (also ..

Creutzfeldt-Jakob disease surveillance in Australia: update to 31 December 2018

Christiane Stehmann, Matteo Senesi, Victoria Lewis, Mairin Ummi, Marion Simpson, Genevieve Klug, Catriona McLean, Colin Masters, Steven Collins

Journal article  |  2019  |  Communicable Diseases Intelligence

Creutzfeldt-Jakob disease surveillance in Australia: update to December 2017

Christiane Stehmann, Shannon Sarros, Matteo Senesi, Victoria Lewis, Marion Simpson, Catriona McLean, Colin Masters, Steven Collins

Journal article  |  2019  |  Communicable diseases intelligence (2018)

Creutzfeldt–Jakob disease surveillance in Australia: update to December 2017

Christiane Stehmann, Shannon Sarros, Matteo Senesi, Victoria Lewis, Marion Simpson, Catriona McLean, Colin Masters, Steven Collins

Journal article  |  2019  |  Communicable Diseases Intelligence

Nationwide surveillance of human prion diseases (also known as transmissible spongiform encephalopathies), the most common being C..

Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc

Simote Totauhelotu Foliaki, Victoria Lewis, Abu Mohammed Taufiqual Islam, Laura Jane Ellett, Matteo Senesi, David Isaac Finkelstein, Blaine Roberts, Victoria A Lawson, Paul Anthony Adlard, Steven John Collins

Journal article  |  2019  |  PLOS Pathogens

Secreted cellular prion protein binds doxorubicin and correlates with anthracycline resistance in breast cancer

Adrian P Wiegmans, Jodi M Saunus, Sunyoung Ham, Richard Lobb, Jamie R Kutasovic, Andrew J Dalley, Mariska Miranda, Caroline Atkinson, Simote T Foliaki, Kaltin Ferguson, Colleen Niland, Cameron N Johnstone, Victoria Lewis, Steven J Collins, Sunil R Lakhani, Fares Al-Ejeh, Andreas Moller

Journal article  |  2019  |  JCI Insight

Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species

Simote Totauhelotu Foliaki, Victoria Lewis, David Isaac Finkelstein, Victoria Lawson, Harold Arthur Coleman, Matteo Senesi, Abu Mohammed Taufiqual Islam, Feng Chen, Shannon Sarros, Blaine Roberts, Paul Anthony Adlard, Steven John Collins

Journal article  |  2018  |  PLOS Pathogens

Acute Neurotoxicity Models of Prion Disease

AMT Islam, PA Adlard, DI Finkelstein, V Lewis, S Biggi, E Biasini, SJ Collins

Journal article  |  2018  |  ACS Chemical Neuroscience

In vivo prion models and the disconnection between transmissibility and neurotoxicity

Matteo Senesi, Victoria Lewis, Jee H Kim, Paul A Adlard, David I Finkelstein, Steven J Collins

Journal article  |  2017  |  Ageing Research Reviews

Molecular Subtyping of PrPres in Human Sporadic CJD Brain Tissue

GM Klug, V Lewis, SJ Collins

Book Chapter  |  2017  |  Methods in Molecular Biology

Analysis of Cellular Prion Protein Endoproteolytic Processing

Victoria Lewis

Journal article  |  2017  |  Methods in molecular biology (Clifton, N.J.)

Prion protein "gamma-cleavage": characterizing a novel endoproteolytic processing event

Victoria Lewis, Vanessa A Johanssen, Peter J Crouch, Genevieve M Klug, Nigel M Hooper, Steven J Collins

Journal article  |  2016  |  CELLULAR AND MOLECULAR LIFE SCIENCES

A Genome Wide Association Study Links Glutamate Receptor Pathway to Sporadic Creutzfeldt-Jakob Disease Risk

Pascual Sanchez-Juan, Matthew T Bishop, Gabor G Kovacs, Miguel Calero, Yurii S Aulchenko, Anna Ladogana, Alison Boyd, Victoria Lewis, Claudia Ponto, Olga Calero, Anna Poleggi, Angel Carracedo, Sven J van der Lee, Thomas Stroebel, Fernando Rivadeneira, Albert Hofman, Stephane Haik, Onofre Combarros, Jose Berciano, Andre G Uitterlinden, et al.

Journal article  |  2015  |  PLOS ONE

The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro

Steven J Collins, Carolin Tumpach, Qiao-Xin Li, Victoria Lewis, Timothy M Ryan, Blaine Roberts, Simon C Drew, Victoria A Lawson, Cathryn L Haigh

Journal article  |  2015  |  STEM CELL RESEARCH & THERAPY

Unusual Clinical and Molecular-Pathological Profile of Gerstmann-Straussler-Scheinker Disease Associated With a Novel PRNP Mutation (V176G)

Marion Simpson, Vanessa Johanssen, Alison Boyd, Genevieve Klug, Colin L Masters, Qiao-Xin Li, Roger Pamphlett, Catriona McLean, Victoria Lewis, Steven J Collins

Journal article  |  2013  |  JAMA NEUROLOGY

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection

Layla Sinclair, Victoria Lewis, Steven J Collins, Cathryn L Haigh

Journal article  |  2013  |  DISEASE MODELS & MECHANISMS

Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity

Victoria Lewis, Cathryn L Haigh, Colin L Masters, Andrew F Hill, Victoria A Lawson, Steven J Collins

Journal article  |  2012  |  MOLECULAR NEURODEGENERATION

Examining C3 cleavage of the cellular prion protein

Victoria Lewis, Nigel Hooper, Steven Collins

Conference Proceedings  |  2012  |  PRION

Cellular Prion Protein Expression Is Not Regulated by the Alzheimer's Amyloid Precursor Protein Intracellular Domain

Victoria Lewis, Isobel J Whitehouse, Herbert Baybutt, Jean C Manson, Steven J Collins, Nigel M Hooper

Journal article  |  2012  |  PLOS ONE

Acute exposure to prion infection induces transient oxidative stress progressing to be cumulatively deleterious with chronic propagation in vitro

Cathryn L Haigh, Amelia R McGlade, Victoria Lewis, Colin L Masters, Victoria A Lawson, Steven J Collins

Journal article  |  2011  |  Free Radical Biology and Medicine

The role of lipid rafts in prion protein biology

V Lewis, NM Hooper

Journal article  |  2011  |  Frontiers in Bioscience

The role of lipid rafts in prion protein biology

Victoria Lewis, Nigel M Hooper

Journal article  |  2011  |  Frontiers in Bioscience

Proteolytic processing of the prion protein

V Lewis

Book Chapter  |  2011

The Cellular and Molecular Biology of Prion Disease

VA Lawson, SJ Collins, undefined Haigh, undefined Lewis, V Wall, MW Brazier, S Hawke, RA Bessen, JC Bartz, AE Kincaid, LJ Vella, R Cappai, AF Hill, L Gadtke, G Lutzny, C Krammer, R Bester, I Vorberg, M Bishop, JM Welton, et al.

Book  |  2011

No evidence for prion protein gene locus multiplication in Creutzfeldt-Jakob disease

Steven J Collins, Maaike Schuur, Alison Boyd, Victoria Lewis, Genevieve M Klug, Amelia McGlade, Andrew van Oosterhout, Guido Breedveld, Ben A Oostra, Colin Masters, Cornelia M Van Duijn

Journal article  |  2010  |  Neuroscience Letters

PrPC-related signal transduction is influenced by copper, membrane integrity and the alpha cleavage site

Cathryn L Haigh, Victoria A Lewis, Laura J Vella, Colin L Masters, Andrew F Hill, Victoria A Lawson, Steven J Collins

Journal article  |  2009  |  Cell Research

C-11-PiB PET studies in typical sporadic Creutzfeldt-Jakob disease

VL Villemagne, CA McLean, K Reardon, A Boyd, V Lewis, G Klug, G Jones, D Baxendale, CL Masters, CC Rowe, SJ Collins

Journal article  |  2009  |  Journal of Neurology, Neurosurgery and Psychiatry

Surveillance of Creutzfeldt-Jakob disease in Australia: 2009 update.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Amelia McGlade, Christiane Stehmann, Colin L Masters, Steven J Collins

Journal article  |  2009  |  Communicable Diseases Intelligence

In Australia, the occurrence of all human transmissible spongiform encephalopathies (TSEs) is surveyed by the Australian National ..

Surveillance of Creutzfeldt-Jakob disease in Australia: 2008.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Amelia R McGlade, Helene Roberts, Samantha L Douglass, Colin L Masters, Steven J Collins

Journal article  |  2008  |  Communicable Diseases Intelligence

Australia-wide surveillance of all human transmissible spongiform encephalopathies (TSEs) is performed by the Australian National ..

Analysis of endogenous PrPC processing in neuronal and non-neuronal cell lines.

Victoria Lewis, Steven J Collins

Book Chapter  |  2008  |  Methods in Molecular Biology

Numerous transmembrane and glycosylphosphatidylinositol (GPI)-anchored proteins, covering a vast range of structural and functiona..

Analysis of endogenous PrPC processing in neuronal and non-neuronal cell lines

V Lewis, SJ Collins

Journal article  |  2008  |  Methods in Molecular Biology

Molecular typing of PrPres in human sporadic CJD brain tissue

V Lewis, GM Klug, AF Hill, SJ Collins

Journal article  |  2008  |  Methods in Molecular Biology

Molecular typing of PrPres in human sporadic CJD brain tissue.

Victoria Lewis, Genevieve M Klug, Andrew F Hill, Steven J Collins

Book Chapter  |  2008  |  Methods in Molecular Biology

Within the spectrum of sporadic human transmissible spongiform encephalopathies (TSEs), there is considerable diversity of disease..

Creutzfeldt-Jakob disease: Australian surveillance update to March 2007.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Samantha L Douglass, Helene Roberts, Rebecca Argent, Colin L Masters, Steven J Collins

Journal article  |  2007  |  Communicable Diseases Intelligence

From October 1993, prospective, national surveillance of the rare class of neurodegenerative diseases known as transmissible spong..

Novel prion protein gene mutation presenting with subacute PSP-like syndrome

DB Rowe, V Lewis, M Needham, M Rodriguez, A Boyd, C McLean, H Roberts, CL Masters, SJ Collins

Journal article  |  2007  |  Neurology

Correlative studies support lipid peroxidation is linked to PrPres propagation as art early primary pathogenic event in prion disease

MW Brazier, V Lewis, GD Ciccotosto, GM Klub, VA Lawson, R Cappai, JW Ironside, CL Masters, AF Hill, AR White, S Collins

Journal article  |  2006  |  Brain Research Bulletin

Creutzfeldt-Jakob disease: Australian surveillance update to December 2005.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Samantha L Douglass, Rebecca Argent, James S Lee, Colin L Masters, Steven J Collins, undefined Australian National Creutzfeldt-Jakob Disease Registry

Journal article  |  2006  |  Communicable Diseases Intelligence

Australia-wide prospective surveillance of human transmissible spongiform encephalopathies (TSEs) has been conducted by the Austra..

Extended period of asymptomatic prion disease after low dose inoculation: Assessment of detection methods and implications for infection control

SJ Collins, V Lewis, MW Brazier, AF Hill, VA Lawson, GM Klug, CL Masters

Journal article  |  2005  |  Neurobiology of Disease

Australian sporadic CJD analysis supports endogenous determinants of molecular-clinical profiles

V Lewis, AF Hill, GM Klug, A Boyd, CL Masters, SJ Collins

Journal article  |  2005  |  Neurology

Creutzfeldt-Jakob disease: Australian surveillance update to 31 December 2004.

Genevieve M Klug, Alison Boyd, Victoria Lewis, Madga Kvasnicka, James S Lee, Colin L Masters, Steven J Collins

Journal article  |  2005  |  Communicable Diseases Intelligence

The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) was established in October 1993 after the identification of pr..

Biochemical analysis of peripheral tissue involvement in transmissible spongiform encephalopathies

VA Lawson, AF Hill, V Lewis, R Sharples, S Collins, CL Masters

Conference Proceedings  |  2005  |  Prions: Food and Drug Safety

Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies

M Pocchiari, M Puopolo, EA Croes, H Budka, E Gelpi, S Collins, V Lewis, T Sutcliffe, A Guilivi, N Delasnerie-Laupretre, JP Brandel, A Alperovitch, I Zerr, S Poser, HA Kretzschmar, A Ladogana, I Rietvald, E Mitrova, P Martinez-Martin, J de Pedro-Cuesta, et al.

Journal article  |  2004  |  Brain

Creutzfeldt-Jakob disease surveillance in Australia

GMJ KLUG, V LEWIS, A BOYD, JS LEE, CL MASTERS, SJ COLLINS

Journal article  |  2004  |  Communicable Diseases Intelligence

Novel prion protein insert mutation associated with prolonged neurodegenerative illness

V Lewis, S Collins, AF Hill, A Boyd, CA McLean, M Smith, CL Masters

Journal article  |  2003  |  Neurology

Apparently sporadic CJD and covert health-care transmissions

V Lewis, A Boyd, CL Masters, SJ Collins

Journal article  |  2002  |  The Lancet Neurology

Creutzfeldt-Jakob disease in Australia 1970-1999

S Collins, A Boyd, JS Lee, V Lewis, A Fletcher, CA McLean, M Law, J Kaldor, MJ Smith, CL Masters

Journal article  |  2002  |  Neurology

Incidence of human astrovirus in central Australia (1995 to 1998) and comparison of deduced serotypes detected from 1981 to 1998

RD Schnagl, K Belfrage, R Farrington, K Hutchinson, V Lewis, J Erlich, F Morey

Journal article  |  2002  |  Journal of Clinical Microbiology

Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model

SJ Collins, V Lewis, M Brazier, AF Hill, A Fletcher, CL Masters

Journal article  |  2002  |  Annals of Neurology

Transmissible spongiform encephalopathies in Australia.

A Boyd, A Fletcher, JS Lee, V Lewis, CL Masters, SJ Collins

Journal article  |  2001  |  Communicable Diseases Intelligence

The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) commenced surveillance in September 1993 as part of the Common..