Michael Souter

RIPK3 controls MAIT cell accumulation during development but not during infection

Timothy Patton, Zhe Zhao, Xin Yi Lim, Eleanor Eddy, Huimeng Wang, Adam G Nelson, Bronte Ennis, Sidonia BG Eckle, Michael NT Souter, Troi J Pediongco, Hui-Fern Koay, Jian-Guo Zhang, Tirta M Djajawi, Cynthia Louis, Najoua Lalaoui, Nicolas Jacquelot, Andrew M Lew, Daniel G Pellicci, James McCluskey, Yifan Zhan, et al.

Journal article  |  2023  |  CELL DEATH & DISEASE

Cell death mechanisms in T lymphocytes vary according to their developmental stage, cell subset and activation status. The cell de..

CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells

Michael NT Souter, Wael Awad, Shihan Li, Troi Pediongco, Bronwyn S Meehan, Lucy J Meehan, Zehua Tian, Zhe Zhao, Huimeng Wang, Adam Nelson, Jérôme Le Nours, Yogesh Khandokar, T Praveena, Jacinta Wubben, Jie Lin, Lucy C Sullivan, George Lovrecz, Jeffrey YW Mak, Ligong Liu, Lyudmila Kostenko, et al.

Journal article  |  2022  |  Journal of Experimental Medicine

Mucosal-associated invariant T (MAIT) cells detect microbial infection via recognition of riboflavin-based antigens presented by t..

Human mucosal V alpha 7.2( )CD161(hi) T cell distribution at physiologic state and in Helicobacter pylori infection

Norasate Boonpattanaporn, Thidarat Kongkaew, Panjana Sengprasert, Michael NT Souter, Narisorn Lakananurak, Rungsun Rerknimitr, Alexandra J Corbett, Rangsima Reantragoon

Journal article  |  2022  |  JOURNAL OF LEUKOCYTE BIOLOGY

Mucosal-associated invariant T (MAIT) cells are innate-like, unconventional T cells that are present in peripheral blood and mucos..

The balance of interleukin-12 and interleukin-23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection

Huimeng Wang, Adam G Nelson, Bingjie Wang, Zhe Zhao, Xin Yi Lim, Mai Shi, Lucy J Meehan, Xiaoxiao Jia, Katherine Kedzierska, Bronwyn S Meehan, Sidonia BG Eckle, Michael NT Souter, Troi J Pediongco, Jeffrey YW Mak, David P Fairlie, James McCluskey, Zhongfang Wang, Alexandra J Corbett, Zhenjun Chen

Journal article  |  2022  |  IMMUNOLOGY AND CELL BIOLOGY

Mucosal-associated invariant T (MAIT) cells are a major subset of innate-like T cells mediating protection against bacterial infec..

When it's good to have MAITs

Michael NT Souter, James McCluskey, Alexandra J Corbett

Journal article  |  2020  |  IMMUNOLOGY AND CELL BIOLOGY

This article discusses mucosal-associated invariant T-cell prophylactic and therapeutic vaccination schemes tested by Sakai et al...

Biased MAIT TCR Usage Poised for Limited Antigen Diversity?

Michael NT Souter, Sidonia BG Eckle

Journal article  |  2020  |  FRONTIERS IN IMMUNOLOGY

Mucosal-associated invariant T (MAIT) cells are a subset of unconventional T cells that recognize the evolutionarily conserved maj..

Hypersensitivities following allergen antigen recognition by unconventional T cells

Marcela de Lima Moreira, Michael NT Souter, Zhenjun Chen, Liyen Loh, James McCluskey, Daniel G Pellicci, Sidonia BG Eckle

Journal article  |  2020  |  ALLERGY

Conventional T cells recognise protein-derived antigens in the context of major histocompatibility complex (MHC) class Ia and clas..

A class of gamma delta T cell receptors recognize the underside of the antigen-presenting molecule MR1

Jerome Le Nours, Nicholas A Gherardin, Sri H Ramarathinam, Wael Awad, Florian Wiede, Benjamin S Gully, Yogesh Khandokar, T Praveena, Jacinta M Wubben, Jarrod J Sandow, Andrew I Webb, Anouk von Borstel, Michael T Rice, Samuel J Redmond, Rebecca Seneviratna, Maria L Sandoval-Romero, Shihan Li, Michael NT Souter, Sidonia BG Eckle, Alexandra J Corbett, et al.

Journal article  |  2019  |  SCIENCE

T cell receptors (TCRs) recognize antigens presented by major histocompatibility complex (MHC) and MHC class I-like molecules. We ..

Characterization of Human Mucosal-associated Invariant T (MAIT) Cells

Michael NT Souter, Liyen Loh, Shihan Li, Bronwyn S Meehan, Nicholas A Gherardin, Dale I Godfrey, Jamie Rossjohn, David P Fairlie, Katherine Kedzierska, Daniel G Pellicci, Zhenjun Chen, Lars Kjer-Nielsen, Alexandra J Corbett, James McCluskey, Sidonia BG Eckle

Journal article  |  2019  |  Current protocols in immunology

Mucosal‐associated invariant T (MAIT) cells are a subset of unconventional T cells restricted by the major histocompatibility comp..

CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells

Peter Reinink, Michael NT Souter, Tan-Yun Cheng, Tamara van Gorkom, Stefanie Lenz, Joanna Kubler-Kielb, Klemen Strle, Kristin Kremer, Steven FT Thijsen, Allen C Steere, Dale I Godfrey, Daniel G Pellicci, D Branch Moody, Ildiko Van Rhijn

Journal article  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Lyme disease is a common multisystem disease caused by infection with a tick-transmitted spirochete, Borrelia burgdorferi and rela..