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Dr

Katharina Hochheiser

Senior Research Officer
Microbiology And Immunology
immunology
melanoma
autoimmunity
viral infections
skin disease
CRISPR/Cas9
T cells
animals
mice
Katharina Hochheiser's Profile Picture
Dr

Katharina Hochheiser

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
T cell mediated immune response in peripheral tissues
Katharina Hochheiser's Profile Picture
Dr

Katharina Hochheiser

 

My current research focuses on T-cell mediated immune responses in peripheral tissues, which I am highly interested in because knowledge about the molecular mechanisms might be translated into treatment of a great variety of diseases. I am especially interested in the development and function of Tissue Resident Memory T cells, which remain in tissues after infection and have been shown to play a major role in protective but also harmful immune responses.

My PhD was carried out under the supervision of Prof. Christian Kurts in Bonn, Germany, and focused on Dendritic Cells in the kidney.

I characterized DCs from different compartments of the kidney in the steady state and in different nephritis models and demonstrated the dependence of effector T cell responses on the presence of mature DCs.
In November 2014 I joined the lab of Assoc. Prof. Thomas Gebhardt at the University of Melbourne, who is an expert on memory T cells and shares my interest in immune cell functions in peripheral tissues. My research now focuses on T cell immunity in the skin. Using mouse models of skin infection, autoimmunity and melanoma in combination with gene editing techniques such as ectopic expression and CRISPR/Cas9 mediated knockout, I investigate the development and function of Tissue Resident Memory T cells and their role in different skin diseases.
In collaboration with Dr. David Gyorki, who is a surgeon at the Peter MacCallum Cancer Centre, we have recently started to work with human samples. Applying multiplex immunohistochemistry, we are investigating whether we can translate findings from our animal models into the clinic.

Projects

Displaying the most recent project by Katharina Hochheiser.

Scholarly Works

Displaying the 22 most recent scholarly works by Katharina Hochheiser.

Honours, Awards and Fellowships

2018

RJS Thomas Translational Research Prize

Peter MacCallum Cancer Centre, Cancer Surgery Research Committee

2018

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2014

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2010

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Awards

Credentials

Positions


Senior Research Officer

Microbiology And Immunology

Australasian Society For Immunology

Australasian Society for Immunology

German Society For Immunology

German Society for Immunology

Education


Dr. rer. nat.

University of Bonn