Asif Noor

Assessment of the epi-pericardial fibrotic substrate by collagen-targeted probes

Martin Ezeani, Asif Noor, Paul S Donnelly, Be'eri Niego, Christoph E Hagemeyer

Journal article  |  2022  |  SCIENTIFIC REPORTS

The identification of the fibrotic arrhythmogenic substrate as a means of improving the diagnosis and prediction of atrial fibrill..

Collagen-Targeted Peptides for Molecular Imaging of Diffuse Cardiac Fibrosis

Martin Ezeani, Asif Noor, Karen Alt, Sean Lal, Paul S Donnelly, Christoph E Hagemeyer, Be'eri Niego

Journal article  |  2021  |  JOURNAL OF THE AMERICAN HEART ASSOCIATION

Background Cardiac fibrosis is the excessive deposition of extracellular matrix in the heart, triggered by a cardiac insult, aging..

Imaging Somatostatin Positive Tumors with Tyr(3)-Octreotate/Octreotide Conjugated to Desferrioxamine B Squaramide Radiolabeled with either Zirconium-89 or Gallium-68

Asif Noor, Jessica K Van Zuylekom, Stacey E Rudd, Peter D Roselt, Mohammad B Haskali, Eddie Yan, Michael Wheatcroft, Rodney J Hicks, Carleen Cullinane, Paul S Donnelly

Journal article  |  2021  |  BIOCONJUGATE CHEMISTRY

Radiolabeled derivatives of Tyr3-octreotide and Tyr3-octreotate, synthetic analogues of the peptide hormone somatostatin, can be u..

Bivalent Inhibitors of Prostate-Specific Membrane Antigen Conjugated to Desferrioxamine B Squaramide Labeled with Zirconium-89 or Gallium-68 for Diagnostic Imaging of Prostate Cancer

Asif Noor, Jessica K Van Zuylekom, Stacey E Rudd, Kelly Waldeck, Peter D Roselt, Mohammad B Haskali, Michael P Wheatcroft, Eddie Yan, Rodney J Hicks, Carleen Cullinane, Paul S Donnelly

Journal article  |  2020  |  JOURNAL OF MEDICINAL CHEMISTRY

Prostate-specific membrane antigen (PSMA) is a carboxypeptidase that is overexpressed in prostate cancer and is an excellent candi..

Copper Bis(thiosemicarbazonato)-stilbenyl Complexes That Bind to Amyloid-beta Plaques

Asif Noor, David J Hayne, SinChun Lim, Jessica K Van Zuylekom, Carleen Cullinane, Peter D Roselt, Catriona A McLean, Jonathan M White, Paul S Donnelly

Journal article  |  2020  |  INORGANIC CHEMISTRY

Alzheimer's disease is characterized by the presence of extracellular amyloid-β plaques. Positron emission tomography (PET) imagin..

Charge neutral rhenium tricarbonyl complexes of tridentate N-heterocyclic carbene ligands that bind to amyloid plaques of Alzheimer's disease

Nuchareenat Wiratpruk, Asif Noor, Catriona A McLean, Paul S Donnelly, Peter J Barnard

Journal article  |  2020  |  DALTON TRANSACTIONS

Two tridentate ligand systems bearing N-heterocyclic carbene (NHC), amine and carboxylate donor groups coupled to benzothiazole- o..

Potential Diagnostic Imaging of Alzheimer's Disease with Copper-64 Complexes That Bind to Amyloid-beta Plaques

Lachlan E McInnes, Asif Noor, Kai Kysenius, Carleen Cullinane, Peter Roselt, Catriona A McLean, Francis CK Chiu, Andrew K Powell, Peter J Crouch, Jonathan M White, Paul S Donnelly

Journal article  |  2019  |  INORGANIC CHEMISTRY

Amyloid-β plaques, consisting of aggregated amyloid-β peptides, are one of the pathological hallmarks of Alzheimer's disease. Copp..

Synthesis of Amidines by Palladium-Mediated CO2 Extrusion Followed by Insertion of Carbodiimides: Translating Mechanistic Studies to Develop a One-Pot Method

Yang Yang, Asif Noor, Allan J Canty, Alireza Ariafard, Paul S Donnelly, Richard AJ O'Hair

Journal article  |  2019  |  ORGANOMETALLICS

A palladium-mediated one-pot synthesis of amidines from aromatic carboxylic acids and carbodiimides (RNCNR) is reported as an isoe..

A Copper Complex of a Thiosemicarbazone-Pyridylhydrazone Ligand Containing a Vinylpyridine Functional Group as a Potential Imaging Agent for Amyloid-beta Plaques

Lachlan E McInnes, Asif Noor, Peter D Roselt, Catriona A McLean, Jonathan M White, Paul S Donnelly

Journal article  |  2019  |  AUSTRALIAN JOURNAL OF CHEMISTRY

Complexes containing positron-emitting radionuclides of copper have the potential to be of use for diagnostic imaging with positro..

Rhenium and technetium complexes of thioamide derivatives of pyridylhydrazine that bind to amyloid-beta plaques

Scott P Fletcher, Asif Noor, James L Hickey, Catriona A McLean, Jonathan M White, Paul S Donnelly

Journal article  |  2018  |  JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Age-associated deposition of amyloid-β in cerebral blood vessels, a condition referred to as cerebral amyloid angiopathy, can cont..