Liam Fearnley

An interaction map of circulating metabolites, immune gene networks, and their genetic regulation

Artika P Nath, Scott C Ritchie, Sean G Byars, Liam G Fearnley, Aki S Havulinna, Anni Joensuu, Antti J Kangas, Pasi Soininen, Annika Wennerstrom, Lili Milani, Andres Metspalu, Satu Mannisto, Peter Wurtz, Johannes Kettunen, Emma Raitoharju, Mika Kahonen, Markus Juonala, Aarno Palotie, Mika Ala-Korpela, Samuli Ripatti, et al.

Journal article  |  2017  |  GENOME BIOLOGY

BACKGROUND: Immunometabolism plays a central role in many cardiometabolic diseases. However, a robust map of immune-related gene n..

Metabolomics in epidemiology: from metabolite concentrations to integrative reaction networks

Liam G Fearnley, Michael Inouye

Journal article  |  2016  |  INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Metabolomics is becoming feasible for population-scale studies of human disease. In this review, we survey epidemiological studies..

A Scalable Permutation Approach Reveals Replication and Preservation Patterns of Network Modules in Large Datasets

Scott C Ritchie, Stephen Watts, Liam G Fearnley, Kathryn E Holt, Gad Abraham, Michael Inouye

Journal article  |  2016  |  CELL SYSTEMS

Network modules-topologically distinct groups of edges and nodes-that are preserved across datasets can reveal common features of ..

The Biomarker GlycA Is Associated with Chronic Inflammation and Predicts Long-Term Risk of Severe Infection

Scott C Ritchie, Peter Wurtz, Artika P Nath, Gad Abraham, Aki S Havulinna, Liam G Fearnley, Antti-Pekka Sarin, Antti J Kangas, Pasi Soininen, Kristiina Aalto, Ilkka Seppala, Emma Raitoharju, Marko Salmi, Mikael Maksimow, Satu Mannisto, Mika Kahonen, Markus Juonala, Samuli Ripatti, Terho Lehtimaki, Sirpa Jalkanen, et al.

Journal article  |  2015  |  CELL SYSTEMS

The biomarker glycoprotein acetylation (GlycA) has been shown to predict risk of cardiovascular disease and all-cause mortality. H..

Extracting reaction networks from databases-opening Pandora's box

Liam G Feamley, Melissa J Davis, Mark A Ragan, Lars K Nielsen

Journal article  |  2014  |  BRIEFINGS IN BIOINFORMATICS

Large quantities of information describing the mechanisms of biological pathways continue to be collected in publicly available da..

Honey Production and Compositional Parameters

L FEARNLEY

Book Chapter  |  2014

This book presents information key to understanding how antioxidants change during production of a wide variety of food products, ..

Towards a Large Integrated Model of Signal Transduction and Gene Regulation Events in Mammalian Cells

Liam G Fearnley, Mark A Ragan, Lars K Nielsen

Conference Proceedings  |  2014  |  BIOINFORMATICS 2014: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON BIOINFORMATICS MODELS, METHODS AND ALGORITHMS

PATHLOGIC-S: A Scalable Boolean Framework for Modelling Cellular Signalling

Liam G Fearnley, Lars K Nielsen

Journal article  |  2012  |  PLOS ONE

Curated databases of signal transduction have grown to describe several thousand reactions, and efficient use of these data requir..

Compositional analysis of manuka honeys by high-resolution mass spectrometry: Identification of a manuka-enriched archetypal molecule

Liam Fearnley, David R Greenwood, Michael Schmitz, Jonathan M Stephens, Ralf C Schlothauer, Kerry M Loomes

Journal article  |  2012  |  Food Chemistry

Phenolic compounds and methylglyoxal in some New Zealand manuka and kanuka honeys

Jonathan M Stephens, Ralf C Schlothauer, Bruce D Morris, Derek Yang, Liam Fearnley, David R Greenwood, Kerry M Loomes

Journal article  |  2010  |  Food Chemistry