Abdel Belaidi

Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE ε4, sex and age.

Scott Ayton, Shorena Janelidze, Blaine Roberts, Sebastian Palmqvist, Pawel Kalinowski, Ibrahima Diouf, Abdel A Belaidi, Erik Stomrud, Ashley I Bush, Oskar Hansson

Journal article  |  2020  |  Progress in Neurobiology

It is unknown how neuroinflammation may feature in the etiology of Alzheimer's disease (AD). We profiled acute phase response (APR..

Cu-II(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease

Adam Southon, Kathryn Szostak, Karla M Acevedo, Krista A Dent, Irene Volitakis, Abdel A Belaidi, Kevin J Barnham, Peter J Crouch, Scott Ayton, Paul S Donnelly, Ashley Bush

Journal article  |  2020  |  British Journal of Pharmacology

BACKGROUND AND PURPOSE: Diacetyl-bis(4-methyl-3-thiosemicarbazonato)copperII (CuII (atsm)) ameliorates neurodegeneration and delay..

Cellular Senescence and Iron Dyshomeostasis in Alzheimer's Disease

Shashank Masaldan, Abdel Ali Belaidi, Scott Ayton, Ashley Bush

Journal article  |  2019  |  PHARMACEUTICALS

Iron dyshomeostasis is a feature of Alzheimer's disease (AD). The impact of iron on AD is attributed to its interactions with the ..

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice

Abdel A Belaidi, Adam P Gunn, Bruce X Wong, Scott Ayton, Ambili T Appukuttan, Blaine R Roberts, James A Duce, Ashley I Bush

Journal article  |  2018  |  Neurotherapeutics

S-sulfocysteine/NMDA receptor-dependent signaling underlies neurodegeneration in molybdenum cofactor deficiency

Avadh Kumar, Borislav Dejanovic, Florian Hetsch, Marcus Semtner, Debora Fusca, Sita Arjune, Jose Angel Santamaria-Araujo, Aline Winkelmann, Scott Ayton, Ashley I Bush, Peter Kloppenburg, Jochen C Meier, Guenter Schwarz, Abdel Ali Belaidi

Journal article  |  2017  |  JOURNAL OF CLINICAL INVESTIGATION

Targeting Transition Metals for Neuroprotection in Alzheimer's Disease

S Ayton, AA Belaidi, P Lei, AI Bush

Book Chapter  |  2017

The Complex Role of Apolipoprotein E in Alzheimer's Disease: an Overview and Update

Laura Mahoney-Sanchez, Abdel Ali Belaidi, Ashley I Bush, Scott Ayton

Journal article  |  2016  |  JOURNAL OF MOLECULAR NEUROSCIENCE

Efficacy and safety of cyclic pyranopterin monophosphate substitution in severe molybdenum cofactor deficiency type A: a prospective cohort study

Bernd C Schwahn, Francjan J Van Spronsen, Abdel A Belaidi, Stephen Bowhay, John Christodoulou, Terry G Derks, Julia B Hennermann, Elisabeth Jameson, Kai Koenig, Tracy L McGregor, Esperanza Font-Montgomery, Jose A Santamaria-Araujo, Saikat Santra, Mamta Vaidya, Anne Vierzig, Evangeline Wassmer, Ilona Weis, Flora Y Wong, Alex Veldman, Guenter Schwarz

Journal article  |  2015  |  The Lancet