Ellen Menkhorst

Jagged1 regulates endometrial receptivity in both humans and mice

Wei Zhou, Ellen Menkhorst, Evdokia Dimitriadis

Journal article  |  2021  |  FASEB JOURNAL

The human endometrium undergoes cycle-dependent changes and is only receptive to an implanting blastocyst within a narrow window o..

Prednisolone Alters Endometrial Decidual Cells and Affects Decidual-Trophoblast Interactions

Eliza Grbac, Teresa So, Swati Varshney, Nicholas Williamson, Evdokia Dimitriadis, Ellen Menkhorst

Journal article  |  2021  |  FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

Poor pregnancy outcomes such as recurrent pregnancy loss (RPL) and preeclampsia are associated with impaired decidualization and a..

MAML1: a coregulator that alters endometrial epithelial cell adhesive capacity.

Sadaf Zafir, Wei Zhou, Ellen Menkhorst, Leilani Santos, Evdokia Dimitriadis

Journal article  |  2021  |  Fertil Res Pract

BACKGROUND: Abnormalities in endometrial receptivity has been identified as a major barrier to successful embryo implantation. End..

Recurrent pregnancy loss

Evdokia Dimitriadis, Ellen Menkhorst, Shigeru Saito, William H Kutteh, Jan J Brosens

Journal article  |  2020  |  NATURE REVIEWS DISEASE PRIMERS

Recurrent pregnancy loss is a distressing pregnancy disorder experienced by ~2.5% of women trying to conceive. Recurrent pregnancy..

Profilin-1 is dysregulated in endometroid (type I) endometrial cancer promoting cell proliferation and inhibiting pro-inflammatory cytokine production

Lisanne George, Amy Winship, Kelli Sorby, Evdokia Dimitriadis, Ellen Menkhorst

Journal article  |  2020  |  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endometrial cancer (EC) is the most common gynaecological malignancy. Alarmingly its incidence and mortality rate is increasing pa..

Galectin-7 Impairs Placentation and Causes Preeclampsia Features in Mice

Ellen Menkhorst, Wei Zhou, Leilani L Santos, Sarah Delforce, Teresa So, Kate Rainczuk, Hannah Loke, Argyro Syngelaki, Swati Varshney, Nicholas Williamson, Kirsty Pringle, Morag J Young, Kypros H Nicolaides, Yves St-Pierre, Eva Dimitriadis

Journal article  |  2020  |  Hypertension

Preeclampsia is a serious pregnancy-induced disorder unique to humans. The etiology of preeclampsia is poorly understood; however,..

Restoration of microRNA-29c in type I endometrioid cancer reduced endometrial cancer cell growth

Michelle Van Sinderen, Meaghan Griffiths, Ellen Menkhorst, Keith Niven, Evdokia Dimitriadis

Journal article  |  2019  |  ONCOLOGY LETTERS

Endometrial cancer is the most common gynaecological cancer worldwide, and the prognosis of patients with advanced disease remains..

Trophoblast function is altered by decidual factors in gestational-dependant manner

EM Menkhorst, M Van Sinderen, J Correia, E Dimitriadis

Journal article  |  2019  |  PLACENTA

Inadequate implantation and placentation is associated with miscarriage and placental insufficiency. The decidual environment is t..

Decidual-Secreted miRs: Essential Mediators of Maternal-Fetal Dialogue during Early Pregnancy.

Ellen Menkhorst, Kate Rainczuk, Eva Dimitriadis

Conference Proceedings  |  2019  |  REPRODUCTIVE SCIENCES

Galectin-7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration

Ellen Menkhorst, Meaghan Griffiths, Michelle Van Sinderen, Kate Rainczuk, Keith Niven, Evdokia Dimitriadis

Journal article  |  2018  |  ONCOLOGY LETTERS

Endometrial cancer (EC) is the most commonly diagnosed gynecological malignancy in Australian women. Notably, its incidence and mo..