Shuai Li

Modifiable lifestyle factors and severe COVID-19 risk: a Mendelian randomisation study.

Shuai Li, Xinyang Hua

Journal article  |  2021  |  BMC Medical Genomics

BACKGROUND: Lifestyle factors including obesity and smoking are suggested to be correlated with increased risk of COVID-19 severe ..

Biological Aging Measures Based on Blood DNA Methylation and Risk of Cancer: A Prospective Study.

Pierre-Antoine Dugué, Julie K Bassett, Ee Ming Wong, JiHoon E Joo, Shuai Li, Chenglong Yu, Daniel F Schmidt, Enes Makalic, Nicole Wong Doo, Daniel D Buchanan, Allison M Hodge, Dallas R English, John L Hopper, Graham G Giles, Melissa C Southey, Roger L Milne

Journal article  |  2021  |  JNCI Cancer Spectrum

Background: We previously investigated the association between 5 "first-generation" measures of epigenetic aging and cancer risk i..

Novel mammogram-based measures improve breast cancer risk prediction beyond an established mammographic density measure

Tuong L Nguyen, Daniel F Schmidt, Enes Makalic, Gertraud Maskarinec, Shuai Li, Gillian S Dite, Ye K Aung, Christopher F Evans, Ho N Trinh, Laura Baglietto, Jennifer Stone, Yun-Mi Song, Joohon Sung, Robert J MacInnis, Pierre-Antoine Dugue, James G Dowty, Mark A Jenkins, Roger L Milne, Melissa C Southey, Graham G Giles, et al.

Journal article  |  2020  |  International Journal of Cancer

Mammograms contain information that predicts breast cancer risk. We developed two novel mammogram-based breast cancer risk measure..

Genetic and environmental causes of variation in epigenetic aging across the lifespan

Shuai Li, Tuong L Nguyen, Ee Ming Wong, Pierre-Antoine Dugue, Gillian S Dite, Nicola J Armstrong, Jeffrey M Craig, Karen A Mather, Perminder S Sachdev, Richard Saffery, Joohon Sung, Qihua Tan, Anbupalam Thalamuthu, Roger L Milne, Graham G Giles, Melissa C Southey, John L Hopper

Journal article  |  2020  |  Clinical Epigenetics

BACKGROUND: DNA methylation-based biological age (DNAm age) is an important biomarker for adult health. Studies in specific age ra..

Are the Relationships of Lean Mass and Fat Mass With Bone Microarchitecture Causal or Due to Familial Confounders? A Novel Study of Adult Female Twin Pairs.

Minh Bui, Roger Zebaze, Shuai Li, John L Hopper, Åshild Bjørnerem

Journal article  |  2020  |  JBMR Plus

It is not known whether the relationships of lean mass (LM) and fat mass (FM) with bone microarchitecture and geometry are causal ..

Inference about causation from examination of familial confounding (ICE FALCON): a model for assessing causation analogous to Mendelian randomization

Shuai Li, Minh Bui, John L Hopper

Journal article  |  2020  |  International Journal of Epidemiology

BACKGROUND: We developed a method to make Inference about Causation from Examination of FAmiliaL CONfounding (ICE FALCON) using ob..

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

Ben Brumpton, Eleanor Sanderson, Karl Heilbron, Fernando Pires Hartwig, Sean Harrison, Gunnhild Aberge Vie, Yoonsu Cho, Laura D Howe, Amanda Hughes, Dorret I Boomsma, Alexandra Havdahl, John Hopper, Michael Neale, Michel G Nivard, Nancy L Pedersen, Chandra A Reynolds, Elliot M Tucker-Drob, Andrew Grotzinger, Laurence Howe, Tim Morris, et al.

Journal article  |  2020  |  Nature Communications

Novel mammogram-based measures improve breast cancer risk prediction beyond an established mammographic density measure

Tuong Nguyen, Daniel Schmidt, Enes Makalic, Gertraud Maskarinec, Shuai Li, Gillian Dite, Ye Aung, Christopher Evans, Ho Trinh, Laura Baglietto, Jennifer Stone, Yun-Mi Song, Joohon Sung, Robert MacInnis, Pierre-Antoine Dugué, James Dowty, Mark Jenkins, Roger Milne, Melissa Southey, Graham Giles, et al.

Journal article  |  2020

ABSTRACT Mammograms contain information that predicts breast cancer risk. We developed two novel mammogram-based breast cancer ris..

Causes of variation in epigenetic aging across the lifespan

Shuai Li, Tuong Nguyen, Ee Ming Wong, Pierre-Antoine Dugué, Gillian Dite, Nicola Armstrong, Jeffrey Craig, Karen Mather, Perminder Sachdev, Richard Saffery, Joohon Sung, Qihua Tan, Anbupalam Thalamuthu, Roger Milne, Graham Giles, Melissa Southey, John Hopper

Journal article  |  2020

Background DNA methylation-based biological age (DNAm age) is potentially an important biomarker for adult health. Studies in spec..

Environmental temperature and human epigenetic modifications: A systematic review.

Rongbin Xu, Shuai Li, Shuaijun Guo, Qi Zhao, Michael J Abramson, Shanshan Li, Yuming Guo

Journal article  |  2020  |  Environmental Pollution

The knowledge about the effects of environmental temperature on human epigenome is a potential key to understand the health impact..