Frank Vajda

The outcome of altering antiepileptic drug therapy before pregnancy

FJE Vajda, TJ O'Brien, JE Graham, AA Hitchcock, CM Lander, MJ Eadie

Journal article  |  2020  |  Epilepsy & Behavior

A rat model of valproate teratogenicity from chronic oral treatment during pregnancy

Dana Jazayeri, Emma Braine, Stuart McDonald, Sebastian Dworkin, Kim L Powell, Karen Griggs, Frank JE Vajda, Terence J O'Brien, Nigel C Jones

Journal article  |  2020  |  Epilepsia

Pregnancy after valproate withdrawal-Fetal malformations and seizure control

Frank JE Vajda, Terence J O'Brien, Janet E Graham, Alison A Hitchcock, Cecilie M Lander, Mervyn J Eadie

Journal article  |  2020  |  Epilepsia

Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load

Piero Perucca, Alison Anderson, Dana Jazayeri, Alison Hitchcock, Janet Graham, Marian Todaro, Torbjorn Tomson, Dina Battino, Emilio Perucca, Meritxell Martinez Ferri, Anne Rochtus, Lieven Lagae, Maria Paola Canevini, Elena Zambrelli, Ellen Campbell, Bobby PC Koeleman, Ingrid E Scheffer, Samuel F Berkovic, Patrick Kwan, Sanjay M Sisodiya, et al.

Journal article  |  2020  |  Annals of Neurology

OBJECTIVE: The mechanisms by which antiepileptic drugs (AEDs) cause birth defects (BDs) are unknown. Data suggest that AED-induced..

Preexisting illness, fetal malformation, and seizure control rates in pregnant women with epilepsy

Frank John Emery Vajda, Terence John O'Brien, Janet Elizabeth Graham, Alison Anne Hitchcock, Cecilie Margaret Lander, Mervyn John Eadie

Journal article  |  2020  |  Epilepsy & Behavior

Data from 2182 pregnancies in the Australian Register of antiepileptic drugs in pregnancy that were followed to term, with 1965 fo..

Seizures in infancy in the offspring of women with epilepsy.

Frank JE Vajda, Terence J O'Brien, Janet E Graham, Alison A Hitchcock, Cecilie M Lander, Mervyn J Eadie

Journal article  |  2020  |  Acta Neurologica Scandinavica

OBJECTIVES: To assess (a) the incidence of seizures in the first year of life in infants born to mothers with epilepsy and (b) fac..

Valproate under threat

Frank J Vajda

Journal article  |  2019  |  Australian & New Zealand Journal of Psychiatry

Declining malformation rates with changed antiepileptic drug prescribing An observational study

Torbjorn Tomson, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Emilio Perucca, Anne Sabers, Sanjeev V Thomas, Frank Vajda

Journal article  |  2019  |  Neurology

OBJECTIVE: Changes in prescribing patterns of antiepileptic drugs (AEDs) in pregnant women with epilepsy would be expected to affe..

Antiepileptic drugs and foetal malformation: analysis of 20 years of data in a pregnancy register

FJE Vajda, JE Graham, AA Hitchcock, CM Lander, TJ O'Brien, MJ Eadie

Journal article  |  2019  |  Seizure

Valproate-associated foetal malformations-Rates of occurrence, risks in attempted avoidance

Frank JE Vajda, Terence J O'Brien, Janet E Graham, Alison A Hitchcock, Cecilie M Lander, Mervyn J Eadie

Journal article  |  2019  |  Acta Neurologica Scandinavica

Cesarean section in Australian women with epilepsy

Frank John Emery Vajda, Terence John O'Brien, Janet Elizabeth Graham, Alison Anne Hitchcock, Raphael John Paul Kuhn, Cecilie Margaret Lander, Mervyn John Eadie

Journal article  |  2018  |  Epilepsy & Behavior

Memory Dysfunction in School-Aged Children Exposed Prenatally to Antiepileptic Drugs

Sarah Barton, Caroline Nadebaum, Vicki A Anderson, Frank Vajda, David C Reutens, Amanda G Wood

Journal article  |  2018  |  Neuropsychology

The use of antidepressant drugs in pregnant women with epilepsy: A study from the Australian Pregnancy Register

Niveshan Sivathamboo, Alison Hitchcock, Janet Graham, Shobi Sivathamboo, Zhibin Chen, Terence J O'Brien, Frank JE Vajda

Journal article  |  2018  |  Epilepsia

EURAP registry: inadequate monitoring of prescribed drugs in pregnancy Reply

Torbjorn Tomson, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Emilio Perucca, Anne Sabers, Sanjeev V Thomas, Frank Vajda

Journal article  |  2018  |  The Lancet Neurology

Antiepileptic drug polytherapy in pregnant women with epilepsy

FJE Vajda, TJ O'Brien, JE Graham, AA Hitchcock, CM Lander, MJ Eadie

Journal article  |  2018  |  Acta Neurologica Scandinavica

The role of ethnicity on pregnancy outcomes in women with epilepsy: The need for specific research

Nanya Hao, Janet Graham, Alison Hitchcock, Terence J O'Brien, Frank JE Vajda

Journal article  |  2018  |  Epilepsia

Development of EpiRisk: An online clinical tool for estimating the risk of major congenital malformations in pregnant women treated for epilepsy.

Gabriel Davis Jones, Alison Hitchcock, Frank Vajda, John Craig, Terence J O'Brien, Arjune Sen

Journal article  |  2018  |  Epilepsia Open

Antiepileptic drugs (AEDs) are known to associate with an increased risk of major congenital malformations (MCMs) in children born..

Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry

Torbjorn Tomson, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Emilio Perucca, Anne Sabers, Sanjeev V Thomas, Frank Vajda

Journal article  |  2018  |  The Lancet Neurology

Outcomes of pregnancies in women taking antiepileptic drugs for non-epilepsy indications

Dana Jazayeri, Janet Graham, Alison Hitchcock, Terence J O'Brien, Frank JE Vajda

Journal article  |  2018  |  Seizure

Anti-epileptic drug exposure and risk of foetal death in utero

FJE Vajda, TJ O'Brien, J Graham, AA Hitchcock, CM Lander, MJ Eadie

Journal article  |  2018  |  Acta Neurologica Scandinavica

Predicting epileptic seizure control during pregnancy

Frank JE Vajda, TJ O'Brien, JE Graham, AA Hitchcock, CM Lander, MJ Eadie

Journal article  |  2018  |  Epilepsy & Behavior

Maternal and fetal outcomes associated with vagus nerve stimulation during pregnancy

Anne Sabers, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Emilio Perucca, Sanjeev V Thomas, Torbjorn Tomson, Frank Vajda

Journal article  |  2017  |  Epilepsy Research

Breastfeeding initiation, duration and exclusivity in mothers with epilepsy from South West China

Nanya Hao, Han Jiang, Mengqian Wu, Tianying Pan, Bo Yan, Jie Liu, Jie Mu, Wenyu Liu, Jinmei Li, Terence J O'Brien, Zhibin Chen, Frank Vajda, Dong Zhou

Journal article  |  2017  |  Epilepsy Research

Familial Mesial Temporal Lobe Epilepsy and the Borderland of Deja Vu

Piero Perucca, Douglas E Crompton, Susannah T Bellows, Anne M McIntosh, Tomas Kalincik, Mark R Newton, Frank JE Vajda, Ingrid E Scheffer, Patrick Kwan, Terence J O'Brien, K Meng Tan, Samuel F Berkovic

Journal article  |  2017  |  ANNALS OF NEUROLOGY

My profile in epilepsy

Frank Vajda

Journal article  |  2017  |  Epilepsy & Behavior

Antiepileptic drugs, foetal malformations and spontaneous abortions

FJE Vajda, TJ O'Brien, JE Graham, AA Hitchcock, CM Lander, MJ Eadie

Journal article  |  2017  |  Acta Neurologica Scandinavica

Withdrawal of valproic acid treatment during pregnancy and seizure outcome: Observations from EURAP

Torbjorn Tomson, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Emilio Perucca, Anne Sabers, Sanjeev V Thomas, Frank Vajda

Journal article  |  2016  |  Epilepsia

Antiepileptic drug combinations not involving valproate and the risk of fetal malformations

Frank JE Vajda, Terrence J O'Brien, Cecilie M Lander, Janet Graham, Mervyn J Eadie

Journal article  |  2016  |  Epilepsia

Does pregnancy per se make epilepsy worse?

FJE Vajda, TJ O'Brien, CM Lander, J Graham, MJ Eadie

Journal article  |  2016  |  Acta Neurologica Scandinavica

Ever advise against pregnancy?

M Sazgar, FJE Vajda, CL Harden

Book Chapter  |  2016

Is carbamazepine a human teratogen?

FJE Vajda, TJ O'Brien, J Graham, CM Lander, MJ Eadie

Journal article  |  2016  |  Journal of Clinical Neuroscience

Dose-dependent teratogenicity of valproate in mono- and polytherapy An observational study

Torbjorn Tomson, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Emilio Perucca, Anne Sabers, Sanjeev V Thomas, Frank Vajda

Journal article  |  2015  |  Neurology

Antiepileptic drugs and intrauterine death A prospective observational study from EURAP

Torbjoern Tomson, Dina Battino, Erminio Bonizzoni, John J Craig, Dick Lindhout, Emilio Perucca, Anne Sabers, Sanjeev V Thomas, Frank Vajda

Journal article  |  2015  |  Neurology

Antiepileptic drug therapy and fetal development

FJE Vajda

Book Chapter  |  2015

Valproate still has a place in women with epilepsy

Piero Perucca, Terence J O'Brien, Mervyn Eadie, Frank JE Vajda

Journal article  |  2015  |  Epilepsia

Prospective assessment of autism traits in children exposed to antiepileptic drugs during pregnancy

Amanda G Wood, Caroline Nadebaum, Vicki Anderson, David Reutens, Sarah Barton, Terence J O'Brien, Frank Vajda

Journal article  |  2015  |  Epilepsia

Names of infamy: Tainted eponyms

FJE Vajda, SM Davis, E Byrne

Journal article  |  2015  |  Journal of Clinical Neuroscience

The outcomes of pregnancy in women with untreated epilepsy

FJE Vajda, TJ O'Brien, J Graham, CM Lander, MJ Eadie

Journal article  |  2015  |  Seizure

The clinical pharmacology of traditional antiepileptic drugs

Frank JE Vajda, Mervyn J Eadie

Journal article  |  2014  |  Epileptic Disorders

The teratogenicity of the newer antiepileptic drugs - an update

FJE Vajda, TJ O'Brien, CM Lander, J Graham, MJ Eadie

Journal article  |  2014  |  Acta Neurologica Scandinavica

The Australian Register of Antiepileptic Drugs in Pregnancy: Changes over time in the epileptic population

FJE Vajda, TJ O'Brien, J Graham, CM Lander, MJ Eadie

Journal article  |  2014  |  Journal of Clinical Neuroscience

The efficacy of the newer antiepileptic drugs in controlling seizures in pregnancy

Frank JE Vajda, Terrence O'Brien, Cecilie Lander, Janet Graham, Mervyn Eadie

Journal article  |  2014  |  Epilepsia

Prediction of the hazard of foetal malformation in pregnant women with epilepsy

FJE Vajda, TJ O'Brien, J Graham, CM Lander, MJ Eadie

Journal article  |  2014  |  Epilepsy Research

Altered cortical thickness following prenatal sodium valproate exposure

Amanda G Wood, Jian Chen, Sarah Barton, Caroline Nadebaum, Vicki A Anderson, Cathy Catroppa, David C Reutens, Terence J O'Brien, Frank Vajda

Journal article  |  2014  |  Annals of Clinical and Translational Neurology

Effect of anti-epileptic drug therapy on the unborn child

Frank JE Vajda

Journal article  |  2014  |  Journal of Clinical Neuroscience

Effects of exposure to antiepileptic drugs during development

Frank Vajda

Journal article  |  2014  |  Nature Reviews Neurology

Associations between particular types of fetal malformation and antiepileptic drug exposure in utero

FJE Vajda, TJ O'Brien, J Graham, CM Lander, MJ Eadie

Journal article  |  2013  |  Acta Neurologica Scandinavica

Associations between particular types of fetal malformation and antiepileptic drug exposure in utero

FJE Vajda, TJ O'Brien, J Graham, CM Lander, MJ Eadie

Journal article  |  2013  |  Acta Neurologica Scandinavica

Dose dependence of fetal malformations associated with valproate

Frank J Vajda, Terence J O'Brien, Janet E Graham, Cecilie M Lander, Mervyn J Eadie

Journal article  |  2013  |  Neurology

Seizure control and treatment changes in pregnancy: Observations from the EURAP epilepsy pregnancy registry

Dina Battino, Torbjorn Tomson, Erminio Bonizzoni, John Craig, Dick Lindhout, Anne Sabers, Emilio Perucca, Frank Vajda

Journal article  |  2013  |  Epilepsia

RATIONALE AND PROGRESS OF AN AUSTRALIAN CLINICAL TRIALS NETWORK: NEUROSCIENCE TRIALS AUSTRALIA (NTA)

F Vajda, T Soulis, G Donnan, S Davis

Conference Proceedings  |  2013  |  EPILEPSIA

ASSOCIATION BETWEEN PARTICULAR FOETAL MALFORMATIONS AND ANTIEPILEPTIC DRUG EXPOSURE

F Vajda, T O'Brien, J Graham, C Lander, M Eadie

Conference Proceedings  |  2013  |  EPILEPSIA

Teratogenesis in repeated pregnancies in antiepileptic drug-treated women

Frank JE Vajda, Terence J O'Brien, Cecilie M Lander, Janet Graham, Annie Roten, Mervyn J Eadie

Journal article  |  2013  |  Epilepsia

Lamotrigine in epilepsy, pregnancy and psychiatry - a drug for all seasons?

Frank JE Vajda, Seetal Dodd, David Horgan

Journal article  |  2013  |  Journal of Clinical Neuroscience

Dose issues in antiepileptic therapy

F Vajda

Journal article  |  2012  |  Journal of Clinical Neuroscience

Teratogenesis in repeated pregnancies in antiepileptic drug-treated women

FJ Vajda, TJ O'Brien, C Lander, JE Graham, A Roten, MJ Eadie

Conference Proceedings  |  2012  |  EUROPEAN JOURNAL OF NEUROLOGY

The prescribing of antiepileptic drugs for pregnant Australian women

Frank JE Vajda, David Horgan, Samantha Hollingworth, Janet Graham, Alison A Hitchcock, Annie Roten, Terence J O'Brien, Cecile M Lander, Mervyn J Eadie

Journal article  |  2012  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

Clinical Study: Teratogenicity of the newer antiepileptic drugs – the Australian experience

FJ Vajda, J Graham, A Roten, CM Lander, TJ O'Brien, M Eadie

Journal article  |  2012  |  Journal of Clinical Neuroscience

Teratogenicity of the newer antiepileptic drugs - the Australian experience

FJE Vajda, J Graham, A Roten, CM Lander, TJ O'Brien, M Eadie

Journal article  |  2012  |  Journal of Clinical Neuroscience

Neurobehavioral Consequences of Prenatal Antiepileptic Drug Exposure

Caroline Nadebaum, Vicki Anderson, Frank Vajda, David Reutens, Amanda Wood

Journal article  |  2012  |  Developmental Neuropsychology

Dose Issues in Epilepsy

FJ Vajda

Journal article  |  2012  |  Journal of Clinical Neuroscience

SECOND GENERATION OF ANTIEPILEPTIC DRUGS (AEDS) DATA FROM THE AUSTRALIAN PREGNANCY REGISTER (APR)

F Vajda, J Graham, A Roten, C Lander, T O'Brien, M Eadie

Conference Proceedings  |  2011  |  EPILEPSIA

VALPROATE DOSE IS AN INDEPENDENT RISK FACTOR FOR AUTISM SPECTRUM DISORDER: EVIDENCE FROM PROSPECTIVE ASSESSMENTS IN THE AUSTRALIAN BRAIN, COGNITION AND ANTIEPILEPTIC DRUGS STUDY

AG Wood, C Nadebaum, VA Anderson, DC Reutens, S Barton, T O'Brien, FV Vajda

Conference Proceedings  |  2011  |  EPILEPSIA

ACADEMIC ACHIEVEMENT OF AUSTRALIAN CHILDREN PRENATALLY EXPOSED TO ANTIEPILEPTIC DRUGS

C Nadebaum, V Anderson, F Vajda, D Reutens, S Barton, A Wood

Conference Proceedings  |  2011  |  EPILEPSIA

The rationale for pregnancy registers for women with epilepsy

Frank JE Vajda, Terence J O'Brien, Cecilie M Lander, Mervyn J Eadie

Journal article  |  2011  |  Medical Journal of Australia

Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry

Torbjorn Tomson, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Anne Sabers, Emilio Perucca, Frank Vajda

Journal article  |  2011  |  The Lancet Neurology

Foetal malformations after exposure to antiepileptic drugs in utero assessed at birth and 12 months later: observations from the Australian pregnancy register

FJE Vajda, J Graham, AA Hitchcock, TJ O'Brien, CM Lander, MJ Eadie

Journal article  |  2011  |  Acta Neurologica Scandinavica

Language skills of school-aged children prenatally exposed to antiepileptic drugs

C Nadebaum, VA Anderson, F Vajda, DC Reutens, S Barton, AG Wood

Journal article  |  2011  |  Neurology

The Australian Brain and Cognition and Antiepileptic Drugs Study: IQ in School-Aged Children Exposed to Sodium Valproate and Polytherapy

Caroline Nadebaum, Vicki Anderson, Frank Vajda, David Reutens, Sarah Barton, Amanda Wood

Journal article  |  2011  |  Journal of the International Neuropsychological Society

The Australian Pregnancy Register of Anti-epileptic Drugs: 10 years of progress

FJE Vajda

Journal article  |  2010  |  Journal of Clinical Neuroscience

Is lamotrigine a significant human teratogen? Observations from the Australian Pregnancy Register

FJE Vajda, JE Graham, AA Hitchcock, TJ O'Brien, CM Lander, MJ Eadie

Journal article  |  2010  |  Seizure - European Journal of Epilepsy

Valproic Acid Use in Pregnancy and Congenital Malformations

Frank Vajda, Terence O'Brien

Journal article  |  2010  |  New England Journal of Medicine

Valproic Acid Use in Pregnancy and Congenital Malformations

Journal article  |  2010  |  New England Journal of Medicine

MALFORMATION RISKS AFTER MONOTHERAPY EXPOSURE TO ANTIEPILEPTIC DRUGS: FIRST REPORT FROM EURAP

D Battino, E Bonizzoni, J Craig, D Lindhout, E Perucca, A Sabers, T Tomson, F Vajda

Conference Proceedings  |  2010  |  EPILEPSIA

The teratogenic risk of antiepileptic drug polytherapy

Frank JE Vajda, Alison A Hitchcock, Janet Graham, Terence J O'Brien, Cecilie M Lander, Mervyn J Eadie

Journal article  |  2010  |  Epilepsia

Changing patterns of antiepileptic drug use in pregnant Australian women

FJE Vajda, S Hollingworth, J Graham, AA Hitchcock, TJ O'Brien, CM Lander, MJ Eadie

Journal article  |  2010  |  Acta Neurologica Scandinavica

The teratogenic risk of antiepileptic drug polytherapy

F VAJDA, A Hitchcock, J Graham, T O'BRIEN, CM Lander, MJ Eadie

Journal article  |  2010  |  Epilepsia

Introduction of intravenous formulations of the antiepileptic drugs levetiracetam and valproate to the Australian market

Frank JE Vajda

Journal article  |  2009  |  Journal of Clinical Neuroscience

Utilization of antiepileptic drugs during pregnancy: Comparative patterns in 38 countries based on data from the EURAP registry

D Battino, E Bonizzoni, J Craig, D Lindhout, E Perucca, A Sabers, T Tomson, F Vajda

Journal article  |  2009  |  Epilepsia

Treatment options for pregnant woman with epilepsy

FJE Vajda

Journal article  |  2008  |  Expert Opinion on Pharmacotherapy

Neurological complications of porphyria

C Solinas, FJE Vajda

Journal article  |  2008  |  Journal of Clinical Neuroscience

Monitoring antiepileptic drug therapy with serum level measurements

Frank JE Vajda

Journal article  |  2007  |  Medical Journal of Australia

Antiepileptic drug exposure and major congenital malformations: The role of pregnancy registries

Torbjorn Tomson, Dina Battino, Jacqueline French, Cynthia Harden, Lewis Holmes, Jim Morrow, Elisabeth Robert-Gnansia, Angela Scheuerle, Frank Vajda, Katarina Wide, Jacki Gordon

Journal article  |  2007  |  Epilepsy and Behavior

Pharmacotherapy of epilepsy: New armamentarium, new issues

Frank JE Vajda

Journal article  |  2007  |  Journal of Clinical Neuroscience

Epileptic seizure control in pregnancy

FJE Vajda, A Hitchcock, J Graham, CM Lander, TJ O'Brien, MJ Eadie

Conference Proceedings  |  2007  |  JOURNAL OF NEUROLOGY

Seizure control and treatment in pregnancy - Observations from the EURAP Epilepsy Pregnancy Registry

T Tomson

Journal article  |  2006  |  Neurology

The case for an Australian national neurosciences trial network

FJE Vajda

Journal article  |  2006  |  Journal of Clinical Neuroscience

Role of valproate across the ages. Treatment of epilepsy in adults

E Ben-Menachem, B Schmitz, T Tomson, F Vajda

Journal article  |  2006  |  Acta Neurologica Scandinavica

Status epilepticus in pregnancy

D Battino, E Bonizzoni, J Craig, D Lindhout, E Perucca, A Sabers, T Tomson, F Vajda

Conference Proceedings  |  2006  |  EPILEPSIA

Pregnancies in women with epilepsy

F VAJDA, T O'BRIEN, J Graham, A Hitchcock, C Lander, M Eadie

Journal article  |  2006  |  Journal of the Royal College of Physicians of Edinburgh

The case for lamotrigine monitoring in pregnancy

F Vajda, C Solinas, J Graham, A Hitchcock, M Eadie

Journal article  |  2006  |  Journal of Clinical Neuroscience

Five year report of the Australian pregnancy registry for women on antiepileptic medication

F Vajda, C Lander, A Hitchcock, J Graham, C Solinas, T O'Brien, D Reutens, M Eadie

Conference Proceedings  |  2005  |  JOURNAL OF THE NEUROLOGICAL SCIENCES

Current approaches to management of depression in Parkinson's Disease

FJE Vajda, C Solinas

Journal article  |  2005  |  Journal of Clinical Neuroscience

Maternal valproate dosage and foetal malformations

FJE Vajda, MJ Eadie

Journal article  |  2005  |  Acta Neurologica Scandinavica

Potential risks associated with high-dose valproate in pregnancy in psychiatric patients

FJE Vajda, C Solinas

Journal article  |  2005  |  Australian & New Zealand Journal of Psychiatry

Letter to the neurology editor

FJE Vajda

Journal article  |  2005  |  Journal of Clinical Neuroscience

Five year data from the Australian Pregnancy Registry for women on antiepileptic medication

FJ Vajda, C Lander, A Hitchcock, J Graham, C Solinas, TJ O'Brien, MJ Eadie

Conference Proceedings  |  2005  |  EPILEPSIA

Should valproate be taken during pregnancy: a reappraisal?

MJ EADIE, FJE VAJDA

Journal article  |  2005  |  Therapeutics and Clinical Risk Management

Anti-epileptics switching problem [4]

F Vajda, SF Berkovic

Journal article  |  2005  |  Australian Journal of Pharmacy

Efficacy and safety of levetiracetam 1000-3000 mg/day in patients with refractory partial-onset seizures: a multicenter, open-label single-arm study

RG Beran, SF Berkovic, AB Black, G Danta, R Hiersemenzel, GJ Schapel, FJE Vajda

Journal article  |  2005  |  Epilepsy Research

EURAP: An international registry of Antiepileptic drugs and pregnancy

T Tomson, D Battino, E Bonizzoni, J Craig, D Lindhout, E Perucca, A Sabers, F Vajda

Journal article  |  2004  |  Epilepsia

Australian pregnancy registry of women taking antiepileptic drugs

F Vajda, C Lander, T O'Brien, A Hitchcock, J Graham, C Solinas, M Eadie, M Cook

Journal article  |  2004  |  Epilepsia

Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy

FJ Vajda, TJ O'Brien, A Hitchcock, J Graham, M Cook, C Lander, MJ Eadie

Journal article  |  2004  |  Journal of Clinical Neuroscience

The influence of gender on the aggravation of absence seizures by carbarnazepine in the low-dose pentylenetetrazol rat model

KJ McLean, TJ O'Brien, MJ Cook, FJE Vajda

Journal article  |  2004  |  Seizure - European Journal of Epilepsy

Epilepsy and porphyria: new perspectives

C Solinas, FJ Vajda

Journal article  |  2004  |  Journal of Clinical Neuroscience

Australian pregnancy registry of women on antiepileptic drugs (AEDS): 5-year results

FJ Vajda, TJ O'Brien, A Hitchcock, J Graham, C Solinas, C Lander, M Eadie

Conference Proceedings  |  2004  |  EPILEPSIA

The Australian registry of anti-epileptic drugs in pregnancy: experience after 30 months

FJ Vajda, TJ O'Brien, A Hitchcock, J Graham, C Lander

Journal article  |  2003  |  Journal of Clinical Neuroscience

Neuroprotection and neurodegenerative disease

FJE VAJDA

Book Chapter  |  2003

Generics - Equal or not? [1] (multiple letters)

R Faull, MM Hendry, SF Berkovic, FJE Vajda

Journal article  |  2003  |  Australian Prescriber

Valproate and neuroprotection

FJE Vajda

Journal article  |  2002  |  Journal of Clinical Neuroscience

Prospective study of local cutaneous reactions in patients receiving IV phenytoin - Reply

TJ O'Brien, FJ Vajda

Journal article  |  2002  |  Neurology

Gabapentin: Chemistry, biotransformation, pharmacokinetics and interactions

FJE VAJDA

Book Chapter  |  2002

Neuroprotection and neurodegenerative disease

FJE Vajda

Journal article  |  2002  |  Journal of Clinical Neuroscience

Prospective study of local cutaneous reactions in patients receiving IV phenytoin

TJ O'Brien, FM Meara, H Matthews, FJ Vajda

Journal article  |  2001  |  Neurology

Epilepsy, depression and antidepressant drugs

MR Salzberg, FJE Vajda

Journal article  |  2001  |  JOURNAL OF CLINICAL NEUROSCIENCE

Monitoring plasma concentrations of anti-epileptic drugs. A change in perception.

FJE VAJDA

Journal article  |  2001  |  Current Therapeutics

Contemporary management of epilepsy in pregnancy

TJ O'Brien, FJ Vajda

Journal article  |  2000  |  The Australian and New Zealand Journal of Obstetrics and Gynaecology

Treatment of epilepsy

FJE Vajda

Journal article  |  2000  |  Current Therapeutics

New antiepileptic drugs.

FJ Vajda

Journal article  |  2000  |  Journal of Clinical Neuroscience

A double-blind, placebo-controlled trial of diclofenac misoprostol in Alzheimer's disease

S Scharf, A Mander, A Ugoni, F Vajda, N Christophidis

Journal article  |  1999  |  Neurology

Methotrexate polyglutamate levels in circulating erythrocytes and polymorphs correlate with clinical efficacy in rheumatoid arthritis.

P Angelis-Stoforidis, FJ Vajda, N Christophidis

Journal article  |  1999  |  Clinical and Experimental Rheumatology

OBJECTIVES: To measure MTX polyglutamates in circulating erythrocytes (E-MTX), mononuclear cells (MNC-MTX) and polymorphs (PMN-MTX..

Determination of lamotrigine in human plasma by high-performance liquid chromatography

P Angelis-Stoforidis, DJ Morgan, TJ O'Brien, FJE Vajda

Journal article  |  1999  |  Journal of Chromatography B: Biomedical Sciences and Applications

Double-blind, placebo-controlled, crossover study of lamotrigine in treatment-resistant generalised epilepsy

RG Beran, SF Berkovic, FM Dunagan, FJE Vajda, G Danta, AB Black, R Mackenzie

Journal article  |  1998  |  Epilepsia

Serum interleukin-6 and interleukin-6 soluble receptor in Alzheimer's disease.

P Angelis, S Scharf, A Mander, F Vajda, N Christophidis

Journal article  |  1998  |  Neuroscience Letters

Serum levels of interleukin-6 (IL-6) and interleukin-6 soluble receptor (IL-6sR) were measured in 41 patients (23 female and 18 ma..

A double-blind, placebo-controlled crossover study of vigabatrin 2 g/day and 3 g/day in uncontrolled partial seizures

RG Beran, SF Berkovic, N Buchanan, G Danta, R Mackenzie, G Schapel, G Sheean, F Vajda

Journal article  |  1996  |  Seizure

DOUBLE-BLIND, PLACEBO-CONTROLLED, CROSSOVER STUDY OF LAMOTRIGINE IN TREATMENT-RESISTANT PARTIAL SEIZURES

GJ SCHAPEL, RG BERAN, FJE VAJDA, SF BERKOVIC, ML MASHFORD, FM DUNAGAN, WC YUEN, G DAVIES

Journal article  |  1993  |  Journal of Neurology, Neurosurgery & Psychiatry

NEW ANTICONVULSANTS

FJE VAJDA

Journal article  |  1992  |  Current Opinion in Neurology and Neurosurgery

Weight reduction and epilepsy.

RG Beran, FJ Vajda

Journal article  |  1991  |  Medical Journal of Australia

EFFECTS OF THE NMDA RECEPTOR ANTAGONIST MK-801 AGAINST AMYGDALOID-KINDLED SEIZURES IN THE RAT

NA YOUNG, SJ LEWIS, FJE VAJDA, PM BEART

Journal article  |  1989  |  Experimental Neurology

RELATIONSHIP BETWEEN THE DOSE-RESPONSE EFFECTS OF DIAZEPAM AND CLOBAZAM ON ELECTROENCEPHALOGRAPHIC PARAMETERS AND ON KINDLED AMYGDALOID SEIZURE ACTIVITY IN RATS

QLG HARRIS, SJ LEWIS, NA YOUNG, FJE VAJDA, B JARROTT

Journal article  |  1988  |  Clinical and Experimental Pharmacology and Physiology

REGIONAL BRAIN CONCENTRATIONS OF CHOLECYSTOKININ IN THE RAT - THE EFFECTS OF KINDLED AND NON-KINDLED SEIZURES

QLG HARRIS, SJ LEWIS, A SHULKES, FJE VAJDA, B JARROTT

Journal article  |  1988  |  Neuropharmacology

DIFFERENCES IN THE DEVELOPMENT OF TOLERANCE OF 2 ANTICONVULSANT BENZODIAZEPINES IN THE AMYGDALOID KINDLED RAT

NA YOUNG, SJ LEWIS, QL HARRIS, B JARROTT, FJE VAJDA

Journal article  |  1988  |  Journal of Pharmacy and Pharmacology

REGIONAL BRAIN CONCENTRATIONS OF NEUROTENSIN FOLLOWING AMYGDALOID KINDLED AND CORTICAL SUPRATHRESHOLD STIMULATION-INDUCED SEIZURES IN THE RAT

A SHULKES, QLG HARRIS, SJ LEWIS, FJE VAJDA, B JARROTT

Journal article  |  1988  |  Neuropeptides

THE DEVELOPMENT OF TOLERANCE TO THE ANTICONVULSANT EFFECTS OF CLONAZEPAM, BUT NOT SODIUM VALPROATE, IN THE AMYGDALOID KINDLED RAT

NA YOUNG, SJ LEWIS, QLG HARRIS, B JARROTT, FJE VAJDA

Journal article  |  1987  |  Neuropharmacology

THE CURRENT STATUS OF MONOAMINE-OXIDASE AND ITS INHIBITORS

B JARROTT, FJE VAJDA

Journal article  |  1987  |  Medical Journal of Australia

MICROCOMPUTER ANALYSIS TECHNIQUES FOR EVALUATION OF BENZODIAZEPINE EFFECTS ON RAT ELECTROCORTICOGRAM

QLG HARRIS, SJ LEWIS, NA YOUNG, FJE VAJDA, B JARROTT

Journal article  |  1987  |  Electroencephalography and Clinical Neurophysiology

The neurochemical and clinical effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in small animals.

GA Donnan, SJ Kaczmarczyk, T Solopotias, P Rowe, RM Kalnins, FJ Vajda, FA Mendelsohn

Journal article  |  1986  |  Clinical and experimental neurology

The recent discovery that 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes a syndrome of Parkinsonism in man and monkey ..

Management of subarachnoid haemorrhage

FJE Vajda, GA Donnan, J Woodward

Journal article  |  1986  |  Australian Journal of Hospital Pharmacy

Clinical experience with clobazam: a new 1,5 benzodiazepine in the treatment of refractory epilepsy.

FJ Vajda, PF Bladin, BJ Parsons

Journal article  |  1985  |  Clinical and experimental neurology

A benzodiazepine drug, clobazam, was evaluated in 14 refractory epileptic patients, nine of whom received the drug double-blind. T..

Drug treatment of epilepsy.

FJ Vajda

Journal article  |  1984  |  Australian family physician

The most important factors in drug management of epilepsy are an accurate diagnosis of the type of seizures; the use of a first li..

Experience with continuous ambulatory EEG monitoring.

SF Berkovic, PF Bladin, MD Conneely, LA Gossat, GR Symington, FJ Vajda

Journal article  |  1984  |  Clinical and experimental neurology

The value of continuous ambulatory EEG monitoring in the management of patients with seizures was assessed. Eighty-seven patients ..

EFFECT OF CIMETIDINE AND RANITIDINE ON CARBAMAZEPINE AND SODIUM VALPROATE PHARMACOKINETICS

LK WEBSTER, GW MIHALY, DB JONES, RA SMALLWOOD, JA PHILLIPS, FJ VAJDA

Journal article  |  1984  |  European Journal of Clinical Pharmacology

EFFECT OF INCREASED BILE-FLOW AND BILE-ACID SECRETION ON THE HEPATIC ELIMINATION OF SODIUM VALPROATE IN THE CAT

AW MARSHALL, GW MIHALY, RA SMALLWOOD, RG HANSON, FJE VAJDA, J PHILLIPS, J BALDAS

Journal article  |  1984  |  Clinical and Experimental Pharmacology and Physiology

COMPARISON OF THE EFFECTS OF CIMETIDINE AND RANITIDINE ON THE PHARMACOKINETICS OF CARBAMAZEPINE AND SODIUM VALPROATE

LK WEBSTER, GW MIHALY, DB JONES, JA PHILLIPS, RA SMALLWOOD, FJ VAJDA

Journal article  |  1983  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE

REASSESSMENT OF THE CONCEPT OF A THERAPEUTIC RANGE OF ANTI-CONVULSANT PLASMA-LEVELS

FJE VAJDA, J AICARDI

Journal article  |  1983  |  Developmental Medicine & Child Neurology

MEASUREMENT OF PLASMA CLONAZEPAM LEVELS - A COMPARISON OF A RADIOIMMUNOASSAY (RIA) WITH GAS-LIQUID-CHROMATOGRAPHY (GLC)

FJE VAJDA, I ROZITIS, D RUTHERFORD, B JARROTT

Journal article  |  1983  |  CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Differentiating between organic and functional seizures: a common diagnostic problem.

FJ Vajda, BR Chambers

Journal article  |  1981  |  Australian Family Physician

The diagnosis of functional seizures is difficult and emotional factors may be important in the cause and triggering of seizures...

Another look at the management of epilepsy.

FJ Vajda

Journal article  |  1981  |  Australian Family Physician

HUMAN-BRAIN, PLASMA, AND CEREBROSPINAL-FLUID CONCENTRATION OF SODIUM VALPROATE AFTER 72 HOURS OF THERAPY

FJE VAJDA, GA DONNAN, J PHILLIPS, PF BLADIN

Journal article  |  1981  |  Neurology

Re: Rectal administration of sodium valproate in status epilepticus

FJE Vajda, GW Mihaly, JL Miles, GA Donnan, PF Bladin

Journal article  |  1980  |  Neurology

Hepatic elimination of sodium valproate (SV)

FJE Vajda, AW Marshall, GW Mihaly

Journal article  |  1980  |  Clinical and Experimental Pharmacology and Physiology

Pharmacokinetic studies of sodium valproate following acute and chronic administration in epileptic patients

GW Mihaly, J Miles, WJ Louis, FJE Vajda

Journal article  |  1979  |  Clinical and Experimental Pharmacology and Physiology

Some aspects of the clinical use of clonazepam in refractory epilepsy.

CM Lander, GA Donnan, PF Bladin, FJ Vajda

Journal article  |  1979  |  Clinical and experimental neurology

Sodium valproate and clonazepam were given in combination to 17 refractory epileptic patients and their progress was reviewed clin..

Comparison of liquid- and gas-liquid chromatographic assays of 5-fluorouracil in plasma.

N Christophidis, G Mihaly, F Vajda, W Louis

Journal article  |  1979  |  Clinical Chemistry

A liquid-chromatographic assay of 5-fluorouracil in plasma is described. Advantages of this procedure over gas chromatography are ..

Lacrimation and 5-fluorouracil.

N Christophidis, I Lucas, FJ Vajda, WJ Louis

Journal article  |  1978  |  Annals of Internal Medicine

Studies of intravenous cefoxitin (MK306).

N Christophidis, JK Dawborn, FJ Vajda

Journal article  |  1978  |  Medical Journal of Australia

The pharmacokinetics of cefoxitin, a new cephamycin antibiotic, were studied in six patients who were undergoing total hip replace..

Sodium valproate: dose-plasma level relationships and interdose fluctuations.

FJ Vajda, GW Mihaly, JL Miles, PM Morris, PF Bladin

Journal article  |  1978  |  Clinical and experimental neurology

Individual dose-plasma level relationships were studied in 14 chronically treated epileptics, 10 of whom were concomitantly receiv..

Patterns of response to levodopa in Parkinson's disease.

FJ Vajda, GA Donnan, PF Bladin

Journal article  |  1978  |  Clinical and experimental neurology

The broad results of the treatment of patients with idiopathic Parkinson's disease who have received levodopa or its variants are ..

Rectal valproate in intractable status epilepticus.

FJ Vajda, GR Symington, PF Bladin

Journal article  |  1977  |  The Lancet

Therapeutic problems related to tonic status epilepticus.

PF Bladin, FJ Vajda, GR Symington

Journal article  |  1977  |  Clinical and experimental neurology

Acute conduction velocity changes in guinea-pigs after administration of diphenylhydantoin.

PM Le Quesne, V Goldberg, F Vajda

Journal article  |  1976  |  Journal of Neurology, Neurosurgery & Psychiatry

Motor nerve conduction velocity was measured after dosing guinea-pigs with 200-400 μmol/kg diphenylhydantoin (DPH) daily for three..

Fluctuations of plasma phenytoin levels on single dose and twice daily dose regimes.

FJ Vajda, J Merory, PF Bladin

Journal article  |  1975  |  Proceedings of the Australian Association of Neurologists

Eight chronic refractory epileptics were studied with regard to frequency of administration of phenytoin. There were no excessive ..

Measurement of plasma concentrations of tolbutamide by simplified gas-liquid chromatography.

FJ Vajda, F Williams, DS Davies

Journal article  |  1974  |  Medical Journal of Australia

[Mammary infarct caused by venous thrombosis during anticoagulant treatment].

I Antohi, O Gheorghiu, F Vajda

Journal article  |  1974  |  CHIRURGIA

Prevalence and treatment of vitamin D deficiency in children on anticonvulsant drugs.

J Silver, TJ Davies, E Kupersmitt, M Orme, A Petrie, F Vajda

Journal article  |  1974  |  Archives of Disease in Childhood

Prophylactic use of antiarrhythmic drugs following myocardial infarction: observations over 12 months.

RR Lovell, RJ Prineas, F Vajda

Journal article  |  1973  |  Singapore Medical Journal

Interaction between phenytoin and the benzodiazepines.

FJ Vajda, RJ Prineas, RR Lovell

Journal article  |  1971  |  British medical journal

The value of phenytoin plasma levels in the treatment of epilepsy.

FJ Vajda

Journal article  |  1970  |  Medical Journal of Australia

Epileptics on phenytoin.

FJ Vajda, RJ Prineas

Journal article  |  1970  |  BMJ

Destruction of bovine parathyroid hormone labeled with 131-I by rat kidney tissue.

FJ Vajda, TJ Martin, RA Melick

Journal article  |  1969  |  Endocrinology