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Mark Walterfang

Niemann-Pick type C disease
science & technology
life sciences & biomedicine
neurosciences & neurology
Mark Walterfang's Profile Picture

Mark Walterfang

Medicine, Dentistry And Health Sciences
Primary Interest
Mark Walterfang's Profile Picture

Mark Walterfang


Dr Mark Walterfang graduated in medicine from University of Queensland with honours in 1993, and completed his Fellowship of the Royal Australian and New Zealand College of Psychiatrists in 2000. From 2001-2002 he worked as a consultant psychiatrist at the Adult Mental Health Rehabilitation Unit at Sunshine Hospital, treating patients with poor-outcome psychiatric disorders, and worked as the Academic Fellow at the University of Melbourne Department of Psychiatry.

From 2003-2005 he was appointed as Senior Research Fellow at the Mental Health Research Institute, involved in neuroimaging research as part of a Stanley Foundation Centre Grant, and from 2006 has been a research fellow at the Melbourne Neuropsychiatry Centre. Since 2003, he has worked as a consultant neuropsychiatrist at the Royal Melbourne Hospital, developing expertise in managing comorbid psychiatric and neurological disorders, neurodegenerative disorders, neurometabolic disorders and atypical dementias. He has also been involved in the unit's Deep Brain Stimulation Programme for treatment-resistant obsessive-compulsive disorder, and in the establishment of the Melbourne Young-Onset Dementia service. He manages a large cohort of adult patients with the rare neurometabolic disorder Niemann-Pick type C (NPC), and has undertaken the first group neuroimaging analyses in NPC adults that have shed light on the brain mechanisms underpinning their neurodegeneration, and provided promising in-vivo markers of illness progression and treatment response.Dr Walterfang has also been involved in the development in a number of clinical tools for use in psychiatric patients in the areas of cognition and behavioural observation, and their validation in a variety of medical, neurological and psychiatric settings since 2000. Dr Walterfang completed his PhD in the shape analysis of the corpus callosum in schizophrenia and related major psychiatric illness. He is undertaking further doctoral research involving the neuroimaging and neuropsychiatric investigation of rare metabolic disorders, and shape analysis of subcortical structures in a range of neurodegenerative disorders. He recently was invited to contribute a new chapter on the Neuropsychiatry of Neurometabolic and Neuroendocrine disorders to the world's most respected reference text in psychiatry, Kaplan and Sadock's "Comprehensive Textbook of Psychiatry", and has authored over 90 National Library of Medicine-indexed scientific papers. He has published in psychiatric journals such as Molecular Psychiatry, British Journal of Psychiatry, American Journal of Psychiatry, Schizophrenia Research and Psychiatric Research; neurological journals including Neurology, Movement Disorders and Cognitive and Behavioural Neurology; metabolic journals including the Journal of Inherited and Metabolic Disease, Molecular Genetics and Metabolism and Orphanet Journal of Rare Diseases, and imaging journals including Neuroimage and Human Brain Mapping. He also serves as an ad-hoc reviewer for the following journals: Archives of General Psychiatry, Brain, Cerebral Cortex, Biological Psychiatry, Movement Disorders, Neuroimage, Human Brain Mapping, International Psychogeriatrics, Journal of Inherited and Metabolic Disease, British Journal of Psychiatry, Schizophrenia Bulletin, Molecular Genetics and Metabolism, and the Journal of Neurology, Neurosurgery and Psychiatry, amongst others.

Scholarly Works

Displaying the 244 most recent scholarly works by Mark Walterfang.

Honours, Awards and Fellowships


Royal Melbourne Research Medal


Dean of Medicine's Prize for Excellence in the PhD Thesis, University of Melbourne


A/Prof Walterfang was awarded the Vice Chancellor's Prize for Excellence in the PhD Thesis, one of only 6 winners out of 542 theses submitted in 2010.

Vice Chancellor's Prize for Excellence in the PhD Thesis, University of Melbourne


FRANZCP - Fellow of the Royal Australian and New Zealand College of Psychiatrists







Member Of Sfn

Society for Neuroscience

Member Of Ans

Australian Neuroscience Society

Member Of Bpa

Biological Psychiatry Australia

International Society To Advance Alzheimer'S Research And Treatment



Section of Neuropsychiatry, RANZCP


International Neuropsychiatric Association


Australasian Society of Psychiatric Research


Doctor of Philosophy

University of Melbourne

Bachelor of Medicine & Bachelor of Surgery, Hons

The University of Queensland