Svenja Fritzlar

Downregulation of MHC Class I Expression by Influenza A and B Viruses

Marios Koutsakos, Hamish EG McWilliam, Turgut E Aktepe, Svenja Fritzlar, Patricia T Illing, Nicole A Mifsud, Anthony W Purcell, Steve Rockman, Patrick C Reading, Julian P Vivian, Jamie Rossjohn, Andrew G Brooks, Jason M Mackenzie, Justine D Mintern, Jose A Villadangos, Thi HO Nguyen, Katherine Kedzierska

Journal article  |  2019  |  FRONTIERS IN IMMUNOLOGY

Manipulation of the MHC-I presentation pathway, and thus limiting MHC-I cell surface expression, is used by many viruses to evade ..

Mouse Norovirus Infection Arrests Host Cell Translation Uncoupled from the Stress Granule-PKR-eIF2 alpha Axis

Svenja Fritzlar, Turgut E Aktepe, Yi-Wei Chao, Nathan D Kenney, Michael R McAllaster, Craig B Wilen, Peter A White, Jason M Mackenzie

Journal article  |  2019  |  MBIO

The integrated stress response (ISR) is a cellular response system activated upon different types of stresses, including viral inf..

The Microtubule-Associated Innate Immune Sensor GEF-H1 Does Not Influence Mouse Norovirus Replication in Murine Macrophages

Svenja Fritzlar, Peter A White, Jason M Mackenzie

Journal article  |  2019  |  VIRUSES-BASEL

Norovirus is an acute infection of the gastrointestinal tract causing rapid induction of vomiting and diarrhoea. The infection is ..

Mouse Norovirus Infection Reduces the Surface Expression of Major Histocompatibility Complex Class I Proteins and Inhibits CD8( ) T Cell Recognition and Activation

Svenja Fritzlar, Sinthujan Jegaskanda, Turgut Esad Aktepe, Julia Emiley Prier, Lauren Elise Holz, Peter A White, Jason M Mackenzie

Journal article  |  2018  |  JOURNAL OF VIROLOGY

Human noroviruses are highly infectious single-stranded RNA (ssRNA) viruses and the major cause of nonbacterial gastroenteritis wo..

Interaction of mouse norovirus (MNV) with the cellular immune response of host cells

Svenja Fritzlar

Thesis / Dissertation  |  2017

Human noroviruses (HuNoV) cause the majority of non-bacterial gastroenteritis cases worldwide and generate an economic burden of 6..

Norovirus Infection: Replication, Manipulation of Host, and Interaction with the Host Immune Response

Soroush T Sarvestani, Ben Cotton, Svenja Fritzlar, Tanya B O'Donnell, Jason M Mackenzie

Journal article  |  2016  |  JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Noroviruses (NoVs) belong to the Caliciviridae family of viruses and are responsible for causing the majority of gastroenteritis o..

Increased Survival in the Red Flour Beetle after Oral Priming with Bacteria-Conditioned Media

Barbara Milutinovic, Svenja Fritzlar, Joachim Kurtz

Journal article  |  2014  |  JOURNAL OF INNATE IMMUNITY

Immune priming is defined as enhanced protection upon secondary exposure to a pathogen. Such enhanced resistance after prior expos..