Robyn Esterbauer

Phenotypic and functional characterization of pharmacologically expanded Vγ9Vδ2 T cells in pigtail macaques

IM Barber-Axthelm, KM Wragg, R Esterbauer, TH Amarasena, VRB Barber-Axthelm, AK Wheatley, AM Gibbon, SJ Kent, JA Juno

Journal article  |  2023  |  iScience

While gaining interest as treatment for cancer and infectious disease, the clinical efficacy of Vγ9Vδ2 T cell-based immunotherapeu..

Cutting Edge: SARS-CoV-2 Infection Induces Robust Germinal Center Activity in the Human Tonsil

Hyon-Xhi Tan, Kathleen M Wragg, Hannah G Kelly, Robyn Esterbauer, Benjamin J Dixon, Jillian SY Lau, Katie L Flanagan, Carolien E van de Sandt, Katherine Kedzierska, James H McMahon, Adam K Wheatley, Jennifer A Juno, Stephen J Kent

Journal article  |  2022  |  JOURNAL OF IMMUNOLOGY

Understanding the generation of immunity to SARS-CoV-2 in lymphoid tissues draining the site of infection has implications for imm..

Establishment and recall of SARS-CoV-2 spike epitope-specific CD4( ) T cell memory

Kathleen M Wragg, Wen Shi Lee, Marios Koutsakos, Hyon-Xhi Tan, Thakshila Amarasena, Arnold Reynaldi, Grace Gare, Penny Konstandopoulos, Kirsty R Field, Robyn Esterbauer, Helen E Kent, Miles P Davenport, Adam K Wheatley, Stephen J Kent, Jennifer A Juno

Journal article  |  2022  |  NATURE IMMUNOLOGY

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination elicit CD4+ T cell responses to the spike p..

Lung-resident memory B cells established after pulmonary influenza infection display distinct transcriptional and phenotypic profiles

Hyon-Xhi Tan, Jennifer A Juno, Robyn Esterbauer, Hannah G Kelly, Kathleen M Wragg, Penny Konstandopoulos, Sheilajen Alcantara, Carolina Alvarado, Robert Jones, Graham Starkey, Boa Zhong Wang, Osamu Yoshino, Thomas Tiang, M Lindsay Grayson, Helen Opdam, Rohit D'Costa, Angela Vago, Laura K Mackay, Claire L Gordon, David Masopust, et al.

Journal article  |  2022  |  SCIENCE IMMUNOLOGY

Recent studies have established that memory B cells, largely thought to be circulatory in the blood, can take up long-term residen..

Poor protective potential of influenza nucleoprotein antibodies despite wide prevalence

Hillary A Vanderven, Robyn Esterbauer, Sinthujan Jegaskanda, Hyon-Xhi Tan, Adam K Wheatley, Stephen J Kent

Journal article  |  2021  |  IMMUNOLOGY AND CELL BIOLOGY

Humans are exposed to influenza virus through periodic infections. Due to these repeated exposures, human populations commonly hav..

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain

Adam K Wheatley, Phillip Pymm, Robyn Esterbauer, Melanie H Dietrich, Wen Shi Lee, Damien Drew, Hannah G Kelly, Li-Jin Chan, Francesca L Mordant, Katrina A Black, Amy Adair, Hyon-Xhi Tan, Jennifer A Juno, Kathleen M Wragg, Thakshila Amarasena, Ester Lopez, Kevin J Selva, Ebene R Haycroft, James P Cooney, Hariprasad Venugopal, et al.

Journal article  |  2021  |  CELL REPORTS

Potent neutralizing monoclonal antibodies are one of the few agents currently available to treat COVID-19. SARS-CoV-2 variants of ..

Protective efficacy of the anti-HIV broadly neutralizing antibody PGT121 in the context of semen exposure

Matthew S Parsons, Anne B Kristensen, Kevin J Selva, Wen Shi Lee, Thakshila Amarasena, Robyn Esterbauer, Adam K Wheatley, Benjamin R Bavinton, Anthony D Kelleher, Andrew E Grulich, Georges Khoury, Jennifer A Juno, Stephen J Kent

Journal article  |  2021  |  EBIOMEDICINE

BACKGROUND: HIV-1 infections occur following viral exposure at anogenital mucosal surfaces in the presence of semen. Semen contain..

Coformulation with Tattoo Ink for Immunological Assessment of Vaccine Immunogenicity in the Draining Lymph Node

Isaac M Barber-Axthelm, Hannah G Kelly, Robyn Esterbauer, Kathleen M Wragg, Anne M Gibbon, Wen Shi Lee, Adam K Wheatley, Stephen J Kent, Hyon-Xhi Tan, Jennifer A Juno

Journal article  |  2021  |  JOURNAL OF IMMUNOLOGY

Characterization of germinal center B and T cell responses yields critical insights into vaccine immunogenicity. Nonhuman primates..

Decay of Fc-dependent antibody functions after mild to moderate COVID-19

Wen Shi Lee, Kevin John Selva, Samantha K Davis, Bruce D Wines, Arnold Reynaldi, Robyn Esterbauer, Hannah G Kelly, Ebene R Haycroft, Hyon-Xhi Tan, Jennifer A Juno, Adam K Wheatley, P Mark Hogarth, Deborah Cromer, Miles P Davenport, Amy W Chung, Stephen J Kent

Journal article  |  2021  |  CELL REPORTS MEDICINE

The capacity of antibodies to engage with immune cells via the Fc region is important in preventing and controlling many infectiou..

Systems serology detects functionally distinct coronavirus antibody features in children and elderly

Kevin J Selva, Carolien E van de Sandt, Melissa M Lemke, Christina Y Lee, Suzanne K Shoffner, Brendon Y Chua, Samantha K Davis, Thi HO Nguyen, Louise C Rowntree, Luca Hensen, Marios Koutsakos, Chinn Yi Wong, Francesca Mordant, David C Jackson, Katie L Flanagan, Jane Crowe, Shidan Tosif, Melanie R Neeland, Philip Sutton, Paul Licciardi, et al.

Journal article  |  2021  |  NATURE COMMUNICATIONS

The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared to children. Examining baseline SARS-CoV-..