Alexander Dobrovic

Donor-specific cell-free DNA as a biomarker in liver transplantation: A review.

Tess McClure, Su Kah Goh, Daniel Cox, Vijayaragavan Muralidharan, Alexander Dobrovic, Adam G Testro

Journal article  |  2020  |  World Journal of Transplantation

Due to advances in modern medicine, liver transplantation has revolutionised the prognosis of many previously incurable liver dise..

High Speed Centrifugation Before Frozen Storage of Plasma Is Critical for Quantitative Analysis of Mitochondrial-Derived Cell-Free DNA

Daniel RA Cox, Boris KL Wong, Luija Yang, Osamu Yoshino, Badam Testro, Vijayaragavan Muralidharan, Alexander Dobrovic

Journal article  |  2020  |  Clinical Chemistry

NTRK and ALK rearrangements in malignant pleural mesothelioma, pulmonary neuroendocrine tumours and non-small cell lung cancer

Jose Luis Leal, Geoffrey Peters, Marcin Szaumkessel, Trishe Leong, Khashayar Asadi, Gareth Rivalland, Hongdo Do, Clare Senko, Paul L Mitchell, Chai Zi Quing, Alexander Dobrovic, Bibhusal Thapa, Thomas John

Journal article  |  2020  |  Lung Cancer

OBJECTIVES: Gene rearrangements involving NTRK1, NTRK2, NTRK3, ROS1 and ALK have been identified in many types of cancer, includin..

DNA repair gene promoter methylation patterns adapt and influence PARP inhibitor response.

Kasenija Nesic, Rachel M Hurley, Cordelia McGehee, Olga Kondrashova, Maria I Harrell, Giada V Zapparoli, Ashan Musafer, Ming E Wong, John Weroha, Xiaonan Hou, Hu Li, Vivian Negron, Kevin Peterson, Paula Schneider, Elizabeth M Swisher, Melissa Southey, Alexander Dobrovic, Matthew Wakefield, Scott H Kaufmann, Clare L Scott

Conference Proceedings  |  2020  |  CLINICAL CANCER RESEARCH

Elevated Plasma Levels of Cell-Free DNA During Liver Transplantation Are Associated With Activation of Coagulation

Osamu Yoshino, Vijayaragavan Muralidharan, Alexander Dobrovic, Su Kah Goh

Journal article  |  2020  |  Liver Transplantation

Cell-free DNA (cfDNA) is emerging as an immuno-modulator in numerous medical conditions including in malignancy, chronic inflammat..

Publisher Correction: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.

Brett W Stringer, Bryan W Day, Rochelle CJ D'Souza, Paul R Jamieson, Kathleen S Ensbey, Zara C Bruce, Yi Chieh Lim, Kate Goasdoué, Carolin Offenhäuser, Seçkin Akgül, Suzanne Allan, Thomas Robertson, Peter Lucas, Gert Tollesson, Scott Campbell, Craig Winter, Hongdo Do, Alexander Dobrovic, Po-Ling Inglis, Rosalind L Jeffree, et al.

Journal article  |  2020  |  Scientific Reports

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Development and validation of a targeted gene sequencing panel for application to disparate cancers

Mark J McCabe, Marie-Emilie A Gauthier, Chia-Ling Chan, Tanya J Thompson, Sunita MC De Sousa, Clare Puttick, John P Grady, Velimir Gayevskiy, Jiang Tao, Kevin Ying, Arcadi Cipponi, Niantao Deng, Alex Swarbrick, Melissa L Thomas, undefined kConFab, Reginald V Lord, Amber L Johns, Maija Kohonen-Corish, Sandra A O'Toole, Jonathan Clark, et al.

Journal article  |  2019  |  Scientific Reports

Next generation sequencing has revolutionised genomic studies of cancer, having facilitated the development of precision oncology ..

The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

Gisella Figlioli, Massimo Bogliolo, Irene Catucci, Laura Caleca, Sandra Viz Lasheras, Roser Pujol, Johanna Kiiski, Taru A Muranen, Daniel R Barnes, Joe Dennis, Kyriaki Michailidou, Manjeet K Bolla, Goska Leslie, Cora M Aalfs, Muriel A Adank, Julian Adlard, Simona Agata, Karen Cadoo, Bjarni A Agnarsson, Thomas Ahearn, et al.

Journal article  |  2019  |  npj Breast Cancer

Breast cancer is a common disease partially caused by genetic risk factors. Germline pathogenic variants in DNA repair genes BRCA1..

Molecular Genomic Profiling of Melanocytic Nevi

Andrew J Colebatch, Peter Ferguson, Felicity Newell, Stephen H Kazakoff, Tom Witkowski, Alexander Dobrovic, Peter A Johansson, Robyn PM Saw, Jonathan R Stretch, Grant A McArthur, Georgina Long, John F Thompson, John Pearson, Graham J Mann, Nicholas K Hayward, Nicola Waddell, Richard A Scolyer, James S Wilmott

Journal article  |  2019  |  Journal of Investigative Dermatology

Human-specific RNA analysis shows uncoupled epithelial-mesenchymal plasticity in circulating and disseminated tumour cells from human breast cancer xenografts

Anthony Tachtsidis, Anh Viet-Phuong Le, Tony Blick, Devika Gunasinghe, Emma De Sousa, Mark Waltham, Alex Dobrovic, Erik W Thompson

Journal article  |  2019  |  Clinical & Experimental Metastasis