Ying Zhang

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

Andre L Samson, Ying Zhang, Niall D Geoghegan, Xavier J Gavin, Katherine A Davies, Michael J Mlodzianoski, Lachlan W Whitehead, Daniel Frank, Sarah E Garnish, Cheree Fitzgibbon, Anne Hempel, Samuel N Young, Annette V Jacobsen, Wayne Cawthorne, Emma J Petrie, Maree C Faux, Kristy Shield-Artin, Najoua Lalaoui, Joanne M Hildebrand, John Silke, et al.

Journal article  |  2020  |  Nature Communications

Mixed lineage kinase domain-like (MLKL) is the terminal protein in the pro-inflammatory necroptotic cell death program. RIPK3-medi..

EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

Jaclyn S Pearson, Cristina Giogha, Sabrina Muhlen, Ueli Nachbur, Chi LL Pham, Ying Zhang, Joanne M Hildebrand, Clare V Oates, Tania Wong Fok Lung, Danielle Ingle, Laura F Dagley, Aleksandra Bankovacki, Emma J Petrie, Gunnar N Schroeder, Valerie F Crepin, Gad Frankel, Seth L Masters, James Vince, James M Murphy, Margaret Sunde, et al.

Journal article  |  2017  |  Nature Microbiology

Identification of a Distinct Substrate-binding Domain in the Bacterial Cysteine Methyltransferase Effectors NleE and OspZ

Ying Zhang, Sabrina Muehlen, Clare V Oates, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2016  |  Journal of Biological Chemistry

Mutagenesis and Functional Analysis of the Bacterial Arginine Glycosyltransferase Effector NleB1 from Enteropathogenic Escherichia coli

Tania Wong Fok Lung, Cristina Giogha, Kristina Creuzburg, Sze Ying Ong, Georgina L Pollock, Ying Zhang, Ka Yee Fung, Jaclyn S Pearson, Elizabeth L Hartland

Journal article  |  2016  |  Infection and Immunity

Post-modern pathogens: surprising activities of translocated effectors from E-coil and Legionella

Jaclyn S Pearson, Ying Zhang, Hayley J Newton, Elizabeth L Hartland

Journal article  |  2015  |  CURRENT OPINION IN MICROBIOLOGY