Catherine Butler has a background in microbiology and the molecular biology of bacteria. After initially working at the CSIRO Division of Animal Health on multivalent vaccines for cattle and sheep, she undertook her PhD through the University of Melbourne on the development of Mannheimia haemolytica, one of the causative agents of bovine shipping disease, as a live vaccine vector.
This work identified iron regulated outer membrane proteins as immunogenic targets for expression from the vaccine vector. Her interest in bacterial iron regulation and the bacterial requirement for iron in order to cause disease in the mammalian host, took her from working on pathogenic bacteria affecting animals to those affecting humans. She has worked in the Melbourne Dental School for several years, during which her research focus has shifted from elucidation of iron transport and genetic control mechanisms within the oral pathobiont Porphyromonas gingivalis, a causative agent of periodontal disease, to elucidation of the oral microbiome in states of health and disease. Her current research interests also include the role that oral bacteria play in chronic diseases such as Alzheimer’s disease and arthritis. Her research into oral bacteria was recognised by the Australian and New Zealand division of the International Association of Dental Research with the Oral Biology Award in 2016.
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Catherine Butler's selected work
Characterisation Of The Regulation Of The Energy Production Pathways In Porphyromonas Ging..
The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromon..
Displaying the 3 most recent projects by Catherine Butler.
Displaying the 23 most recent scholarly works by Catherine Butler.
The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromonas gingivalis
Hong Min Ng, Nada Slakeski, Catherine A Butler, Paul D Veith, Yu-Yen Chen, Sze Wei Liu, Brigitte Hoffmann, Stuart G Dashper, Eric C Reynolds
Journal article | 2019 | Frontiers in Cellular and Infection Microbiology
The prebiotic effect of CPP-ACP sugar-free chewing gum
James R Fernando, Catherine A Butler, Geoffrey G Adams, Helen L Mitchell, Stuart G Dashper, Karen Escobar, Brigitte Hoffmann, Peiyan Shen, Glenn D Walker, Yi Yuan, Coralie Reynolds, Eric C Reynolds
Journal article | 2019 | Journal of Dentistry
OBJECTIVES: To determine if chewing gum containing casein phosphopeptide stabilised amorphous calcium phosphate (CPP-ACP) promoted..
PG1058 Is a Novel Multidomain Protein Component of the Bacterial Type IX Secretion System
Jacqueline E Heath, Christine A Seers, Paul D Veith, Catherine A Butler, Nor A Nor Muhammad, Yu-Yen Chen, Nada Slakeski, Benjamin Peng, Lianyi Zhang, Stuart G Dashper, Keith J Cross, Steven M Cleal, Caroline Moore, Eric C Reynolds
Journal article | 2016 | PLOS ONE
The Porphyromonas gingivalis Ferric Uptake Regulator Orthologue Binds Hemin and Regulates Hemin-Responsive Biofilm Development
Catherine A Butler, Stuart G Dashper, Lianyi Zhang, Christine A Seers, Helen L Mitchell, Deanne V Catmull, Michelle D Glew, Jacqueline E Heath, Yan Tan, Hasnah SG Khan, Eric C Reynolds
Journal article | 2014 | PLoS ONE
Porphyromonas gingivalis Peptidylarginine Deiminase, a Key Contributor in the Pathogenesis of Experimental Periodontal Disease and Experimental Arthritis
Neville Gully, Richard Bright, Victor Marino, Ceilidh Marchant, Melissa Cantley, David Haynes, Catherine Butler, Stuart Dashper, Eric Reynolds, Mark Bartold
Journal article | 2014 | PLoS One
FimR and FimS: Biofilm Formation and Gene Expression in Porphyromonas gingivalis
Alvin Lo, Christine Seers, Stuart Dashper, Catherine Butler, Glenn Walker, Katrina Walsh, Deanne Catmull, Brigitte Hoffmann, Steven Cleal, Patricia Lissel, John Boyce, Eric Reynolds
Journal article | 2010 | Journal of Bacteriology
Response of Porphyromonas gingivalis to Heme Limitation in Continuous Culture
Stuart G Dashper, Ching-Seng Ang, Paul D Veith, Helen L Mitchell, Alvin WH Lo, Christine A Seers, Katrina A Walsh, Nada Slakeski, Dina Chen, J Patricia Lissel, Catherine A Butler, Neil M O'Brien-Simpson, Ian G Barr, Eric C Reynolds
Journal article | 2009 | Journal of Bacteriology
Honours, Awards and Fellowships
Oral Biology Award
Senior Research Fellow Microbiologist
Melbourne Dental School
American Society of Microbiology
International Association for Dental Research
Australian Society for Microbiology
Doctor of Philosophy
University of Melbourne
Bachelor of Science (Honours)
University of Melbourne
Bachelor of Science
University of Melbourne