Catherine Butler has a background in microbiology and the molecular biology of bacteria. After initially working at the CSIRO Division of Animal Health on multivalent vaccines for cattle and sheep, she undertook her PhD through the University of Melbourne on the development of Mannheimia haemolytica, one of the causative agents of bovine shipping disease, as a live vaccine vector.
This work identified iron regulated outer membrane proteins as immunogenic targets for expression from the vaccine vector. Her interest in bacterial iron regulation and the bacterial requirement for iron in order to cause disease in the mammalian host, took her from working on pathogenic bacteria affecting animals to those affecting humans. She has worked in the Melbourne Dental School for several years, during which her research focus has shifted from elucidation of iron transport and genetic control mechanisms within the oral pathobiont Porphyromonas gingivalis, a causative agent of periodontal disease, to elucidation of the oral microbiome in states of health and disease. Her current research interests also include the role that oral bacteria play in chronic diseases such as Alzheimer’s disease and arthritis. Her research into oral bacteria was recognised by the Australian and New Zealand division of the International Association of Dental Research with the Oral Biology Award in 2016.
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Catherine Butler's highlights
Catherine Butler's selected work
A Polymicrobial Aetiology For Alzheimer'S Disease
Research Grant
Metabolic cooperativity betweenPorphyromonas gingivalisandTreponema denticola
Journal article
Characterisation Of The Regulation Of The Energy Production Pathways In Porphyromonas Ging..
Research Grant
The Role of Treponema denticola Motility in Synergistic Biofilm Formation With Porphyromon..
Journal article
Determination Of Iysine Acetylation Targets In Porphyromonas Gingivalis
Research Grant
The prebiotic effect of CPP-ACP sugar-free chewing gum
Journal article
Catherine Butler's selected work
Projects
Displaying the 4 most recent projects by Catherine Butler.
Project Types
4
Research Grant
Additional Information
Recipient of the F. A. Kernot Early to Mid-Career Research Grant 2019, for Identification of the fungal microbiota (mycobiome) associated with subgingival sites of non-resolving periodontitis and health.
Scholarly Works
Displaying the 24 most recent scholarly works by Catherine Butler.
Honours, Awards and Fellowships
Oral Biology Award
Credentials
Positions
Positions
Senior Research Fellow Microbiologist
Melbourne Dental School
Contributing
American Society of Microbiology
Member
International Association for Dental Research
Member
Australian Society for Microbiology
Education
Education
Doctor of Philosophy
University of Melbourne
Bachelor of Science (Honours)
University of Melbourne
Bachelor of Science
University of Melbourne