Benjamin Solomon

IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors

Lauren Giuffrida, Kevin Sek, Melissa A Henderson, Imran G House, Junyun Lai, Amanda XY Chen, Kirsten L Todd, Emma Petley, Sherly Mardiana, Izabela Todorovski, Emily Gruber, Madison J Kelly, Benjamin J Solomon, Stephin J Vervoort, Ricky W Johnstone, Ian A Parish, Paul J Neeson, Lev M Kats, Phillip K Darcy, Paul A Beavis

Journal article  |  2020  |  Molecular Therapy

Chimeric antigen receptor (CAR) T cell therapy has been highly successful in hematological malignancies leading to their US Food a..

Validation of local p16 testing for determination of human papilloma virus status eligibility on a low risk oropharyngeal cancer trial - A Trans-Tasman Radiation Oncology Group study

Richard J Young, Benjamin Solomon, June Corry, Christopher Angel, Lizbeth Kenny, Sandro Porceddu, Christopher Wratten, Andrew Macann, James E Jackson, Alan Herschtal, Danny Rischin

Journal article  |  2020  |  Oral Oncology

OBJECTIVE: Accurate determination of human papilloma virus (HPV) status is critical when identifying patients with oropharyngeal s..

Efficacy of Selpercatinib in RET-Altered Thyroid Cancers

LJ Wirth, E Sherman, B Robinson, B Solomon, H Kang, J Lorch, F Worden, M Brose, J Patel, S Leboulleux, Y Godbert, F Barlesi, JC Morris, TK Owonikoko, DSW Tan, O Gautschi, J Weiss, C de la Fouchardiere, ME Burkard, J Laskin, et al.

Journal article  |  2020  |  New England Journal of Medicine

BACKGROUND: RET mutations occur in 70% of medullary thyroid cancers, and RET fusions occur rarely in other thyroid cancers. In pat..

Efficacy of Selpercatinib in RET Fusion-Positive Non-Small-Cell Lung Cancer

A Drilon, GR Oxnard, DSW Tan, HHF Loong, M Johnson, J Gainor, CE McCoach, O Gautschi, B Besse, BC Cho, N Peled, J Weiss, Y-J Kim, Y Ohe, M Nishio, K Park, J Patel, T Seto, T Sakamoto, E Rosen, et al.

Journal article  |  2020  |  New England Journal of Medicine

BACKGROUND: RET fusions are oncogenic drivers in 1 to 2% of non-small-cell lung cancers (NSCLCs). In patients with RET fusion-posi..

Immunotherapy for Anaplastic Thyroid Carcinoma

Annette M Lim, Benjamin J Solomon

Journal article  |  2020  |  Journal of Clinical Oncology

Real world outcomes in KRAS G12C mutation positive non-small cell lung cancer

Wanyuan Cui, Fanny Franchini, Marliese Alexander, Ann Officer, Hui-Li Wong, Maarten IJzerman, Jayesh Desai, Benjamin J Solomon

Journal article  |  2020  |  Lung Cancer

BACKGROUND: KRAS mutations are found in 20-30 % of non-small cell lung cancers (NSCLC) and were traditionally considered undruggab..

Targeting platelets for improved outcome in KRAS-driven lung adenocarcinoma

Stephanie R Hyslop, Marliese Alexander, Alesha A Thai, Ariena Kersbergen, Andrew J Kueh, Marco J Herold, Jason Corbin, Pradnya Gangatirkar, Ashley P Ng, Benjamin J Solomon, Warren S Alexander, Kate D Sutherland, Emma C Josefsson

Journal article  |  2020  |  Oncogene

Elevated platelet count is associated with poor survival in certain solid cancers, including lung cancer. In addition, experimenta..

Reply to "Emergence of High Level of MET Amplification During Treatment With Selpercatinib in KIF5B-RET NSCLC"

Jessica J Lin, Benjamin J Solomon

Journal article  |  2020  |  Journal of Thoracic Oncology

Ophthalmological assessment of crizotinib in advanced non-small-cell lung cancer

Benjamin J Solomon, Elizabeth E Kim, Maria Winter, Katherine Monti, Yiyun Tang, Keith D Wilner, Sherry Wang, Sai-Hong Ignatius Ou

Journal article  |  2020  |  Lung Cancer

OBJECTIVES: During crizotinib clinical evaluation, visual disturbances, generally of grade 1 severity, were frequently reported ad..

Evaluation of an artificial intelligence clinical trial matching system in Australian lung cancer patients.

Marliese Alexander, Benjamin Solomon, David L Ball, Mimi Sheerin, Irene Dankwa-Mullan, Anita M Preininger, Gretchen Purcell Jackson, Dishan M Herath

Journal article  |  2020  |  JAMIA Open

Objective: The objective of this technical study was to evaluate the performance of an artificial intelligence (AI)-based system f..