Benjamin Solomon

Custom workflows to improve joint variant calling from multiple related tumour samples: FreeBayesSomatic and Strelka2Pass.

S Hollizeck, SQ Wong, B Solomon, D Chandranada, S-J Dawson

Journal article  |  2021  |  Bioinformatics

SUMMARY: This work describes two novel workflows for variant calling that extend the widely used algorithms of Strelka2 and FreeBa..

Current highlights in lung cancer in 2021.

KHJ Lim, BJ Solomon

Journal article  |  2021  |  ESMO Open

Lung cancer

Alesha A Thai, Benjamin J Solomon, Lecia Sequist, Justin F Gainor, Rebecca S Heist

Journal article  |  2021  |  LANCET

Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer-related deaths worldwide with an estim..

Alectinib induces marked red cell spheroacanthocytosis in a near-ubiquitous fashion and is associated with reduced eosin-5-maleimide binding

James A Kuzich, Sarah Heynemann, Niall Geoghegan, Cindy Evelyn, Susan O'Mahoney, Susan Wilson, Janine Campbell, Kelly Rogers, Benjamin Solomon, David Westerman, Sant-Rayn Pasricha

Journal article  |  2021  |  PATHOLOGY

We reviewed haematological investigations for 43 patients treated at a single centre with alectinib, an inhibitor of anaplastic ly..

Complete metabolic response following anaplastic lymphoma kinase (ALK) targeted therapy in a patient with adenocarcinoma of unknown primary with immunohistochemistry/fluorescence in situ hybridisation discordant ALK test results

Grace Chazan, Danielle Forbes, Anand Murugasu, Hui-Li Wong, Benjamin Solomon

Journal article  |  2021  |  INTERNAL MEDICINE JOURNAL

Functional and patient-reported changes in swallowing and voice after combined chemotherapy and radiotherapy for limited-stage small-cell lung cancer

Jacqui Frowen, Karla Gough, Rhys Hughes, Allison Drosdowsky, Mary Duffy, Nicole Kiss, Jo Phipps-Nelson, Shankar Siva, Benjamin Solomon, David Ball

Journal article  |  2021  |  JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY

INTRODUCTION: The purpose of this study was to describe the nature and impact of dysphagia and dysphonia in patients with limited-..

Impact of COVID-19 on cancer service delivery: a follow-up international survey of oncology clinicians.

G Chazan, F Franchini, M Alexander, S Banerjee, L Mileshkin, P Blinman, R Zielinski, D Karikios, N Pavlakis, S Peters, F Lordick, D Ball, G Wright, M IJzerman, BJ Solomon

Journal article  |  2021  |  ESMO Open

BACKGROUND: The COVID-19 pandemic has had a vast impact on cancer service delivery around the world. Previously reported results f..

Novel RET Fusion RET-SEPTIN9 Predicts Response to Selective RET Inhibition With Selpercatinib in Malignant Pheochromocytoma

Angela Mweempwa, Huiling Xu, Joseph HA Vissers, Richard W Tothill, Andrew D Pattison, Andrew P Fellowes, David M Thomas, Gary Richardson, Rodney J Hicks, Sean M Grimmond, Stephen B Fox, Stephen J Luen, Jayesh Desai, Benjamin J Solomon

Journal article  |  2021  |  JCO Precision Oncology

Efficacy of Lorlatinib in Treatment-Naive Patients (pts) With ALK-Positive Advanced Non-Small Cell Lung Cancer (NSCLC) in Relation to EML4-ALK Variant Type and ALK Mutations.

Alessandra Bearz, Jean-Francois Martini, Jacek Jassem, Sang-We Kim, Gee-Chen Chang, Alice Shaw, Deborah Shepard, Elisa Dall'O', Anna Polli, Holger Thurm, Gerard Zalcman, Maria Rosario Garcia Campelo, Konstantin Penkov, Hidetoshi Hayashi, Benjamin J Solomon

Conference Proceedings  |  2021  |  CANCER RESEARCH

Selpercatinib (LOXO-292) in patients (pts) with RET-altered thyroid cancer

Lori J Wirth, Eric J Sherman, Bruce Robinson, Benjamin Solomon, Hyunseok Kang, Jochen H Lorch, Francis Worden, Marcia S Brose, Sophie Leboulleux, Yann Godbert, Marie Meurer, John Morris, Taofeek K Owonikoko, Daniel Shao-Weng Tan, Oliver Gautschi, Jyoti Patel, Luxi Yang, Jennifer Kherani, Maria E Cabanillas, Manisha H Shah

Conference Proceedings  |  2021  |  ANNALS OF ONCOLOGY