Anushi Rajapaksa

Pulmonary Deposition of Radionucleotide-Labeled Palivizumab: Proof-of-Concept Study

Anushi E Rajapaksa, Lien Anh Ha Do, Darren Suryawijaya Ong, Magdy Sourial, Duncan Veysey, Richard Beare, William Hughes, William Yang, Robert J Bischof, Amarin McDonnell, Peter Eu, Leslie Y Yeo, Paul V Licciardi, Edward K Mulholland

Journal article  |  2020  |  Frontiers in Pharmacology

Objective: Current prevention and/or treatment options for respiratory syncytial virus (RSV) infections are limited as no vaccine ..

Lung Recruitment Strategies During High Frequency Oscillatory Ventilation in Preterm Lambs

Martijn Miedema, Karen E McCall, Elizabeth J Perkins, Regina B Oakley, Prue M Pereira-Fantini, Anushi E Rajapaksa, Andreas D Waldmann, David G Tingay, Anton H van Kaam

Journal article  |  2019  |  Frontiers in Pediatrics

Background: High frequency oscillatory ventilation (HFOV) is considered a lung protective ventilation mode in preterm infants only..

Surgery and magnetic resonance imaging increase the risk of hypothermia in infants

Joel M Don Paul, Elizabeth J Perkins, Prue M Pereira-Fantini, Asha Suka, Olivia Farrell, Julia K Gunn, Anushi E Rajapaksa, David G Tingay

Journal article  |  2018  |  Journal of Paediatrics and Child Health

AIM: Maintaining normothermia is a tenet of neonatal care. However, neonatal thermal care guidelines applicable to intra-hospital ..

Time to lung aeration during a sustained inflation at birth is influenced by gestation in lambs

Karen E McCall, Andreas D Waldmann, Prue Pereira-Fantini, Regina Oakley, Martijn Miedema, Elizabeth J Perkins, Peter G Davis, Peter A Dargaville, Stephan H Bohm, Raffaele Dellaca, Magdy Sourial, Emanuela Zannin, Anushi E Rajapaksa, Andre Tan, Andy Adler, Inez Frerichs, David G Tingay

Journal article  |  2017  |  Pediatric Research

BackgroundCurrent sustained lung inflation (SI) approaches use uniform pressures and durations. We hypothesized that gestational-a..

Supraglottic Atomization of Surfactant in Spontaneously Breathing Lambs Receiving Continuous Positive Airway Pressure

Ilaria Milesi, David G Tingay, Anna Lavizzari, Federico Bianco, Emanuela Zannin, Paolo Tagliabue, Fabio Mosca, Maria Luisa Ventura, Anushi Rajapaksa, Elizabeth J Perkins, Don Black, Marco Di Castri, Magdy Sourial, Gerhard Pohlmann, Raffaele L Dellaca

Journal article  |  2017  |  Pediatric Critical Care Medicine

OBJECTIVES: To determine the short-term tolerance, efficacy, and lung deposition of supraglottic atomized surfactant in spontaneou..

Tidal Volume Delivery during the Anesthetic Management of Neonates Is Variable

Thanaa Abouzeid, Elizabeth J Perkins, Prue M Pereira-Fantini, Anushi Rajapaksa, Asha Suka, David G Tingay

Journal article  |  2017  |  The Journal of Pediatrics

OBJECTIVES: To describe expiratory tidal volume (VT) during routine anesthetic management of neonates at a single tertiary neonata..

Effectiveness of individualized lung recruitment strategies at birth: an experimental study in preterm lambs

David G Tingay, Anushi Rajapaksa, Emanuela Zannin, Prue M Pereira-Fantini, Raffaele L Dellaca, Elizabeth J Perkins, Cornelis EE Zonneveld, Andy Adler, Don Black, Inez Frerichs, Anna Lavizzari, Magdy Sourial, Bartlomiej Grychtol, Fabio Mosca, Peter G Davis

Journal article  |  2017  |  American Journal of Physiology - Lung Cellular and Molecular Physiology

Respiratory transition at birth involves rapidly clearing fetal lung liquid and preventing efflux back into the lung while aeratio..

The interrelationship of recruitment maneuver at birth, antenatal steroids, and exogenous surfactant on compliance and oxygenation in preterm lambs

David G Tingay, Anushi Rajapaksa, Karen McCall, Cornelis EE Zonneveld, Don Black, Elizabeth Perkins, Magdy Sourial, Anna Lavizzari, Peter G Davis

Journal article  |  2016  |  Pediatric Research

BACKGROUND: To describe the interrelationship between antenatal steroids, exogenous surfactant, and two approaches to lung recruit..

Selection of Reference Genes for Gene Expression Studies related to lung injury in a preterm lamb model

Prue M Pereira-Fantini, Anushi E Rajapaksa, Regina Oakley, David G Tingay

Journal article  |  2016  |  Scientific Reports

Preterm newborns often require invasive support, however even brief periods of supported ventilation applied inappropriately to th..

Spatiotemporal Aeration and Lung Injury Patterns Are Influenced by the First Inflation Strategy at Birth

David G Tingay, Anushi Rajapaksa, C Elroy Zonneveld, Don Black, Elizabeth J Perkins, Andy Adler, Bartlomiej Grychtol, Anna Lavizzari, Inez Frerichs, Valerie A Zahra, Peter G Davis

Journal article  |  2016  |  American Journal of Respiratory Cell and Molecular Biology

Ineffective aeration during the first inflations at birth creates regional aeration and ventilation defects, initiating injurious ..