Leslie Roberts

An intronic GAA repeat expansion in FGF14 causes the autosomal-dominant adult-onset ataxia SCA50/ATX-FGF14.

Haloom Rafehi, Justin Read, David J Szmulewicz, Kayli C Davies, Penny Snell, Liam G Fearnley, Liam Scott, Mirja Thomsen, Greta Gillies, Kate Pope, Mark F Bennett, Jacob E Munro, Kathie J Ngo, Luke Chen, Mathew J Wallis, Ernest G Butler, Kishore R Kumar, Kathy Hc Wu, Susan E Tomlinson, Stephen Tisch, et al.

Journal article  |  2023  |  Am J Hum Genet

Adult-onset cerebellar ataxias are a group of neurodegenerative conditions that challenge both genetic discovery and molecular dia..

The Electrophysiological Findings in Spinocerebellar Ataxia Type 6: Evidence From 24 Patients.

WenWen Zhang, Mahi Jasinarachchi, Linda Seiderer, David J Szmulewicz, Leslie J Roberts

Journal article  |  2023  |  J Clin Neurophysiol

PURPOSE: Peripheral neuropathy has been reported commonly in several spinocerebellar ataxia (SCA) types. To date, there is a lack ..

Overview of the Clinical Approach to Individuals With Cerebellar Ataxia and Neuropathy

Leslie J Roberts, Michael McVeigh, Linda Seiderer, Ian H Harding, Louise A Corben, Martin Delatycki, David J Szmulewicz

Journal article  |  2022  |  NEUROLOGY-GENETICS

Increasingly, cerebellar syndromes are recognized as affecting multiple systems. Extracerebellar features include peripheral neuro..

The Presence and Significance of A-Waves-A Retrospective Review of 679 Patients.

WenWen Zhang, Leslie Roberts

Journal article  |  2022  |  J Clin Neurophysiol

PURPOSE: A-waves are late responses that have been reported in healthy individuals and patients with neurologic conditions. The me..

Detecting subtle yet fast skeletal muscle contractions with ultrasoft and durable graphene-based cellular materials

Zijun He, Zheng Qi, Huichao Liu, Kangyan Wang, Leslie Roberts, Jefferson Z Liu, Yilun Liu, Stephen J Wang, Mark J Cook, George P Simon, Ling Qiu, Dan Li

Journal article  |  2022  |  NATIONAL SCIENCE REVIEW

Human bodily movements are primarily controlled by the contractions of skeletal muscles. Unlike joint or skeletal movements that a..

Investigating the Neuroprotective Effect of Oral Omega-3 Fatty Acid Supplementation in Type 1 Diabetes (nPROOFS1): A Randomized Placebo-Controlled Trial

Alexis Ceecee Britten-Jones, Jordan T Kamel, Leslie J Roberts, Sabine Braat, Jennifer P Craig, Richard J MacIsaac, Laura E Downie

Journal article  |  2021  |  DIABETES

This randomized, double-masked, placebo-controlled trial evaluated the effects of oral omega-3 (n-3) fatty acid supplementation on..

Placebo effect in chronic inflammatory demyelinating polyneuropathy: ThePATHstudy and a systematic review

Richard A Lewis, David R Cornblath, Hans-Peter Hartung, Gens Sobue, John-Philip Lawo, Orell Mielke, Billie L Durn, Vera Bril, Ingemar SJ Merkies, Paul Bassett, Alexa Cleasby, Ivo N van Schaik

Journal article  |  2020  |  JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

The Polyneuropathy And Treatment with Hizentra (PATH) study required subjects with chronic inflammatory demyelinating polyneuropat..

Omega-3 polyunsaturated fatty acid oral supplements for improving peripheral nerve health: a systematic review and meta-analysis

Alexis Ceecee Zhang, Manikkuwadura Eranda Harshan De Silva, Richard J MacIsaac, Leslie Roberts, Jordan Kamel, Jennifer P Craig, Ljoudmila Busija, Laura E Downie

Journal article  |  2020  |  NUTRITION REVIEWS

CONTEXT: Peripheral nerve damage can occur in a variety of systemic conditions and can have a profound impact on functional and ps..

Reducing glucose variability with continuous subcutaneous insulin infusion is associated with reversal of axonal dysfunction in type 1 diabetes mellitus

Jordan Kamel, Margaret Loh, Mark Cook, Richard J MacIsaac, Leslie J Roberts

Journal article  |  2020  |  MUSCLE & NERVE

INTRODUCTION: We assess whether improvement in control of type 1 diabetes mellitus (T1DM) with continuous subcutaneous insulin inf..

Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies

Ingemar SJ Merkies, Ivo N van Schaik, Jean-Marc Leger, Vera Bril, Nan van Geloven, Hans-Peter Hartung, Richard A Lewis, Gen Sobue, John-Philip Lawo, Billie L Durn, David R Cornblath, Jan L De Bleecker, Claudia Sommer, Wim Robberecht, Mika Saarela, Jerzy Kamienowski, Zbigniew Stelmasiak, Bjoern Tackenberg, Orell Mielke, A Sabet, et al.

Journal article  |  2019  |  JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Intravenous immunoglobulin (IVIG) is a potential therapy for chronic inflammatory demyelinating polyneuropathy (CIDP). To investig..