Ian Barr

Host-targeted nitazoxanide has a high barrier to resistance but does not reduce the emergence or proliferation of oseltamivir-resistant influenza viruses in vitro or in vivo when used in combination with oseltamivir.

Danielle Tilmanis, Paulina Koszalka, Ian G Barr, Jean-Francois Rossignol, Edin Mifsud, Aeron C Hurt

Journal article  |  2020  |  Antiviral Research

A major limitation of the currently available influenza antivirals is the potential development of drug resistance. The adamantane..

Comparative epidemiology, phylogenetics, and transmission patterns of severe influenza A/H3N2 in Australia from 2003 to 2017.

Jing Xia, Dillon C Adam, Aye Moa, Abrar A Chughtai, Ian G Barr, Naomi Komadina, C Raina MacIntyre

Journal article  |  2020  |  Influenza and Other Respiratory Viruses

BACKGROUND: Over the last two decades, Australia has experienced four severe influenza seasons caused by a predominance of influen..

The impact of climate and antigenic evolution on seasonal influenza virus epidemics in Australia

Edward KS Lam, Dylan H Morris, Aeron C Hurt, Ian G Barr, Colin A Russell

Journal article  |  2020  |  Nature Communications

Although seasonal influenza viruses circulate globally, prevention and treatment occur at the level of regions, cities, and commun..

SARS-CoV-2 does not replicate in embryonated hen's eggs or in MDCK cell lines.

Ian G Barr, Cleve Rynehart, Paul Whitney, Julian Druce

Journal article  |  2020  |  Eurosurveillance

The advent of COVID-19, has posed a risk that human respiratory samples containing human influenza viruses may also contain SARS-C..

Utilising animal models to evaluate oseltamivir efficacy against influenza A and B viruses with reduced in vitro susceptibility

Rubaiyea Farrukee, Celeste Ming-Kay Tai, Ding Yuan Oh, Danielle E Anderson, Vithiagaran Gunalan, Martin Hibberd, Gary Yuk-Fai Lau, Ian G Barr, Veronika von Messling, Sebastian Maurer-Stroh, Aeron C Hurt

Journal article  |  2020  |  PLOS Pathogens

The neuraminidase (NA) inhibitor (NAI) oseltamivir (OST) is the most widely used influenza antiviral drug. Several NA amino acid s..

Pandemic influenza vaccines: What did we learn from the 2009 pandemic and are we better prepared now?

S Rockman, K Laurie, I Barr

Journal article  |  2020  |  Vaccines

In 2009, a novel A(H1N1) influenza virus emerged with rapid human-to-human spread and caused the first pandemic of the 21st centur..

Immunogenicity of the inactivated influenza vaccine in children who have undergone allogeneic haematopoietic stem cell transplant

Anne L Ryan, Ushma D Wadia, Peter Jacoby, Laurence C Cheung, Fiona Kerr, Chris Fraser, Heather Tapp, Francoise Mechinaud, Louise A Carolan, Karen L Laurie, Ian G Barr, Christopher C Blyth, Nicholas G Gottardo, Peter C Richmond, Rishi S Kotecha

Journal article  |  2020  |  Bone Marrow Transplantation

Influenza vaccination is recommended for children following allogeneic haematopoietic stem cell transplant (HSCT), however there i..

Report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza in 2018

Olivia H Price, Natalie Spirason, Cleve Rynehart, Sook Kwan Brown, Angela Todd, Heidi Peck, Manisha Patel, Sally Soppe, Ian G Barr, Michelle K Chow

Journal article  |  2020  |  Communicable Diseases Intelligence

As part of its role in the World Health Organization's (WHO) Global Influenza Surveillance and Response System (GISRS), the WHO Co..

Human respiratory syncytial virus and influenza seasonality patterns-Early findings from the WHO global respiratory syncytial virus surveillance.

Mandeep Chadha, Siddhivinayak Hirve, Christina Bancej, Ian Barr, Elsa Baumeister, Braulia Caetano, Malinee Chittaganpitch, Badarch Darmaa, Joanna Ellis, Rodrigo Fasce, Herve Kadjo, Sandra Jackson, Vivian Leung, Maria Pisareva, Jocelyn Moyes, Amel Naguib, Almiro Tivane, Wenqing Zhang, undefined WHO RSV Surveillance Group

Journal article  |  2020  |  Influenza and Other Respiratory Viruses

BACKGROUND: Human respiratory syncytial virus (RSV) causes illnesses among all age groups and presents a burden to healthcare serv..

Fc functional antibody responses to adjuvanted versus unadjuvanted seasonal influenza vaccination in community-dwelling older adults

Hillary A Vanderven, Ian Barr, Arnold Reynaldi, Adam K Wheatley, Bruce D Wines, Miles P Davenport, P Mark Hogarth, Stephen J Kent

Journal article  |  2020  |  Vaccine

BACKGROUND: Seasonal influenza vaccination with a standard trivalent influenza vaccine (TIV) induces a modest, and cross-reactive,..

Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation

Su-Jhen Hung, Yin-Mei Hsu, Sheng-Wen Huang, Huey-Pin Tsai, Leo Yi Yang Lee, Aeron C Hurt, Ian G Barr, Shin-Ru Shih, Jen-Ren Wang

Journal article  |  2020  |  Journal of Biomedical Science

BACKGROUND: Influenza A viruses cause epidemics/severe pandemics that pose a great global health threat. Among eight viral RNA seg..

Locally Acquired Human Infection with Swine-Origin Influenza A(H3N2) Variant Virus, Australia, 2018

Yi-Mo Deng, Frank YK Wong, Natalie Spirason, Matthew Kaye, Rebecca Beazley, Miguel L Grau, Songhua Shan, Vittoria Stevens, Kanta Subbarao, Sheena Sullivan, Ian G Barr, Vijaykrishna Dhanasekaran

Journal article  |  2020  |  Emerging Infectious Diseases

In 2018, a 15-year-old female adolescent in Australia was infected with swine influenza A(H3N2) variant virus. The virus contained..

Immunogenicity of the inactivated influenza vaccine in children who have undergone autologous stem cell transplant.

Anne L Ryan, Ushma D Wadia, Peter Jacoby, Laurence C Cheung, Fiona Kerr, Chris Fraser, Heather Tapp, Louise A Carolan, Karen L Laurie, Ian G Barr, Christopher C Blyth, Nicholas G Gottardo, Peter C Richmond, Rishi S Kotecha

Journal article  |  2019  |  Bone Marrow Transplantation

The evolution and genetic diversity of avian influenza A(H9N2) viruses in Cambodia, 2015-2016

Annika Suttie, Songha Tok, Sokhoun Yann, Ponnarath Keo, Srey Viseth Horm, Merryn Roe, Matthew Kaye, San Sorn, Davun Holl, Sothyra Tum, Ian G Barr, Aeron C Hurt, Andrew R Greenhill, Erik A Karlsson, Dhanasekaran Vijaykrishna, Yi-Mo Deng, Philippe Dussart, Paul F Horwood

Journal article  |  2019  |  PLOS ONE

Low pathogenic A(H9N2) subtype avian influenza viruses (AIVs) were originally detected in Cambodian poultry in 2013, and now circu..

Diversity of A(H5N1) clade 2.3.2.1c avian influenza viruses with evidence of reassortment in Cambodia, 2014-2016

Annika Suttie, Songha Tok, Sokhoun Yann, Ponnarath Keo, Srey Viseth Horm, Merryn Roe, Matthew Kaye, San Sorn, Davun Holl, Sothyra Tum, Philippe Buchy, Ian Barr, Aeron Hurt, Andrew R Greenhill, Erik A Karlsson, Dhanasekaran Vijaykrishna, Yi-Mo Deng, Philippe Dussart, Paul F Horwood

Journal article  |  2019  |  PLOS ONE

In Cambodia, highly pathogenic avian influenza A(H5N1) subtype viruses circulate endemically causing poultry outbreaks and zoonoti..

Clinical characteristics, predictors, and performance of case definition-Interim results from the WHO global respiratory syncytial virus surveillance pilot.

Siddhivinayak Hirve, Nigel Crawford, Rakhee Palekar, Wenqing Zhang, undefined WHO RSV surveillance Group

Journal article  |  2019  |  Influenza and Other Respiratory Viruses

BACKGROUND: The lack of a uniform surveillance case definition poses a challenge to characterize the epidemiology, clinical featur..

Emergence of Influenza A(H7N4) Virus, Cambodia

Dhanasekaran Vijaykrishna, Yi-Mo Deng, Miguel L Grau, Matthew Kay, Annika Suttie, Paul F Horwood, Wantanee Kalpravidh, Filip Claes, Kristina Osbjer, Phillipe Dussart, Ian G Barr, Erik A Karlsson

Journal article  |  2019  |  Emerging Infectious Diseases

Avian influenza in the Greater Mekong Subregion, 2003-2018

Annika Suttie, Erik A Karlsson, Yi-Mo Deng, Aeron C Hurt, Andrew R Greenhill, Ian G Barr, Philippe Dussart, Paul F Horwood

Journal article  |  2019  |  Infection, Genetics and Evolution

The persistent circulation of avian influenza viruses (AIVs) is an ongoing problem for many countries in South East Asia, causing ..

Semiannual Versus Annual Influenza Vaccination in Older Adults in the Tropics: An Observer-blind, Active-comparator-controlled, Randomized Superiority Trial

Barnaby Young, Sapna Sadarangani, Sen Yew Haur, Chee Fu Yung, Ian Barr, John Connolly, Mark Chen, Annelies Wilder-Smith

Journal article  |  2019  |  Clinical Infectious Diseases

BACKGROUND: Antibody titres and vaccine effectiveness decline within 6 months after influenza vaccination in older adults. Biannua..

Circulation and characterization of seasonal influenza viruses in Cambodia, 2012-2015

Paul F Horwood, Erik A Karlsson, Srey Viseth Horm, Sovann Ly, Seng Heng, Savuth Chin, Chau Darapheak, David Saunders, Lon Chanthap, Sareth Rith, Y Phalla, Kim Lay Chea, Borann Sar, Amy Parry, Vanra Ieng, Reiko Tsuyouka, Yi-Mo Deng, Aeron C Hurt, Ian G Barr, Naomi Komadina, et al.

Journal article  |  2019  |  Influenza and Other Respiratory Viruses

Respiratory illness in a piggery associated with the first identified outbreak of swine influenza in Australia: Assessing the risk to human health and zoonotic potential

DW Smith, IG Barr, R Loh, A Levy, S Tempon, M O'Dea, J Watson, FYK Wong, PV Effler

Journal article  |  2019  |  Tropical Medicine and Infectious Disease

Australia was previously believed to be free of enzootic swine influenza viruses due strict quarantine practices and use of biosec..

Influenza A Virus Infection Induces Viral and Cellular Defective Ribosomal Products Encoded by Alternative Reading Frames

Damien J Zanker, Sara Oveissi, David C Tscharke, Mubing Duan, Siyuan Wan, Xiaomu Zhang, Kun Xiao, Nicole A Mifsud, James Gibbs, Lenny Izzard, Daniel Dlugolenski, Pierre Faou, Karen L Laurie, Nathalie Vigneron, Ian G Barr, John Stambas, Benoit J Van den Eynde, Jack R Bennink, Jonathan W Yewdell, Weisan Chen

Journal article  |  2019  |  The Journal of Immunology

A Tale of Two Mutations: Beginning to Understand the Problems with Egg-Based Influenza Vaccines?

Kanta Subbarao, Ian Barr

Journal article  |  2019  |  Cell Host & Microbe

Human CD8( ) T cell cross-reactivity across influenza A, B and C viruses

Marios Koutsakos, Patricia T Illing, Thi HO Nguyen, Nicole A Mifsud, Jeremy Chase Crawford, Simone Rizzetto, Auda A Eltahla, E Bridie Clemens, Sneha Sant, Brendon Y Chua, Chinn Yi Wong, E Kaitlynn Allen, Don Teng, Pradyot Dash, David F Boyd, Ludivine Grzelak, Weiguang Zeng, Aeron C Hurt, Ian Barr, Steve Rockman, et al.

Journal article  |  2019  |  Nature Immunology

Future pandemic influenza virus detection relies on the existing influenza surveillance systems: A perspective from Australia and New Zealand

LC Jennings, IG Barr

Journal article  |  2019  |  Tropical Medicine and Infectious Disease

The anniversary of the 1918–1919 influenza pandemic has allowed a refocusing on the global burden of influenza and the importance ..

Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness

Ian G Barr, Ruben O Donis, Jacqueline M Katz, John W McCauley, Takato Odagiri, Heidi Trusheim, Theodore F Tsai, David E Wentworth

Journal article  |  2018  |  npj Vaccines

Influenza A(H5N1) viruses with A(H9N2) single gene (matrix or PB1) reassortment isolated from Cambodian live bird markets

Annika Suttie, Erik A Karlsson, Yi-Mo Deng, Srey Viseth Horm, Sokhoun Yann, Songha Tok, San Sorn, Davun Holl, Sothyra Tum, Aeron C Hurt, Andrew R Greenhill, Ian G Barr, Paul F Horwood, Philippe Dussart

Journal article  |  2018  |  Virology

Safety, immunogenicity and protection of A(H3N2) live attenuated influenza vaccines containing wild-type nucleoprotein in a ferret model

Daniil A Korenkov, Karen L Laurie, Patrick C Reading, Louise A Carolan, Kok Fei Chan, Irina I Isakova-Sivak, Tatiana A Smolonogina, Kanta Subbarao, Ian G Barr, Julie Villanueva, Svetlana Shcherbik, Tatiana Bousse, Larisa G Rudenko

Journal article  |  2018  |  Infection, Genetics and Evolution

Divergent Human-Origin Influenza Viruses Detected in Australian Swine Populations

Frank YK Wong, Celeste Donato, Yi-Mo Deng, Don Teng, Naomi Komadina, Chantal Baas, Joyanta Modak, Mark O'Dea, David W Smith, Paul V Effler, Julie Cooke, Kelly R Davies, Aeron Hurt, Nina Kung, Avram Levy, Richmond Loh, Songhua Shan, Mustaghfira W Shinwari, Vittoria Stevens, Joanne Taylor, et al.

Journal article  |  2018  |  Journal of Virology

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection

Kok Fei Chan, Louise A Carolan, Daniil Korenkov, Julian Druce, James McCaw, Patrick C Reading, Ian G Barr, Karen L Laurie

Journal article  |  2018  |  The Journal of Infectious Diseases

Difficulties of predicting the timing, size and severity of influenza seasons

Ian G Barr, Allen C Cheng

Journal article  |  2018  |  Respirology

Detection of Low Pathogenicity Influenza A(H7N3) Virus during Duck Mortality Event, Cambodia, 2017

Annika Suttie, Sokhoun Yann, Y Phalla, Sothyra Tum, Yi-Mo Deng, Vibol Hul, Viseth Srey Horm, Ian Barr, Andrew Greenhill, Paul F Horwood, Kristina Osbjer, Erik A Karlsson, Philippe Dussart

Journal article  |  2018  |  Emerging Infectious Diseases

Ferrets as Models for Influenza Virus Transmission Studies and Pandemic Risk Assessments

Jessica A Belser, Wendy Barclay, Ian Barr, Ron AM Fouchier, Ryota Matsuyama, Hiroshi Nishiura, Malik Peiris, Charles J Russell, Kanta Subbarao, Huachen Zhu, Hui-Ling Yen

Journal article  |  2018  |  Emerging Infectious Diseases

Incidence of influenza A(H3N2) virus infections in Hong Kong in a longitudinal sero-epidemiological study, 2009-2015

Vivian WI Wei, Jessica YT Wong, Ranawaka APM Perera, Kin On Kwok, Vicky J Fang, Ian G Barr, JS Malik Peiris, Steven Riley, Benjamin J Cowling

Journal article  |  2018  |  PLOS ONE

Immune Responses to Twice-Annual Influenza Vaccination in Older Adults in Hong Kong

Yat Hung Tam, Sophie A Valkenburg, Ranawaka APM Perera, Jennifer HF Wong, Vicky J Fang, Tiffany WY Ng, Alfred SK Kwong, Wendy WS Tsui, Dennis KM Ip, Leo LM Poon, Chris KV Chau, Ian G Barr, Joseph S Malik Peiris, Benjamin J Cowling

Journal article  |  2018  |  Clinical Infectious Diseases

Evidence for Viral Interference and Cross-reactive Protective Immunity Between Influenza B Virus Lineages

Karen L Laurie, William Horman, Louise A Carolan, Kok Fei Chan, Daniel Layton, Andrew Bean, Dhanasekaran Vijaykrishna, Patrick C Reading, James M Mccaw, Ian G Barr

Journal article  |  2018  |  The Journal of Infectious Diseases

The cost-effectiveness of trivalent and quadrivalent influenza vaccination in communities in South Africa, Vietnam and Australia

Pieter T de Boer, Joel K Kelso, Nilimesh Haider, Nguyen Thi-Phuong-Lan, Jocelyn Moyes, Cheryl Cohen, Ian G Barr, Maarten J Postma, George J Milne

Journal article  |  2018  |  Vaccine

Pathogenesis, Humoral Immune Responses, and Transmission between Cohoused Animals in a Ferret Model of Human Respiratory Syncytial Virus Infection

Kok Fei Chan, Louise A Carolan, Julian Druce, Keith Chappell, Daniel Watterson, Paul Young, Daniil Korenkov, Kanta Subbarao, Ian G Barr, Karen L Laurie, Patrick C Reading

Journal article  |  2018  |  Journal of Virology

Influenza virus detection: driving change in public health laboratories in the Western Pacific Region

Raynal C Squires, Patrick C Reading, Sheena G Sullivan, Ian G Barr, Frank Konings

Journal article  |  2018  |  Western Pacific surveillance and response journal : WPSAR

Continental synchronicity of human influenza virus epidemics despite climactic variation

Jemma L Geoghegan, Aldo F Saavedra, Sebastian Duchene, Sheena Sullivan, Ian Barr, Edward C Holmes

Journal article  |  2018  |  PLOS Pathogens

The first external quality assessment of isolation and identification of influenza viruses in cell culture in the Asia Pacific region, 2016

Patrick C Reading, Vivian K Leung, Iwona Buettner, Leah Gillespie, Yi-Mo Deng, Robert Shaw, Natalie Spirason, Angela Todd, Aparna Singh Shah, Frank Konings, Ian G Barr

Journal article  |  2017  |  Journal of Clinical Virology

Epidemiology and Relative Severity of Influenza Subtypes in Singapore in the Post-Pandemic Period from 2009 to 2010

Ee Hui Goh, Lili Jiang, Jung Pu Hsu, Linda Wei Lin Tan, Wei Yen Lim, Meng Chee Phoon, Yee Sin Leo, Ian G Barr, Vincent Tak Kwong Chow, Vernon J Lee, Cui Lin, Raymond Lin, Sapna P Sadarangani, Barnaby Young, Mark I-Cheng Chen

Journal article  |  2017  |  Clinical Infectious Diseases

Multiplex Reverse Transcription-PCR for Simultaneous Surveillance of Influenza A and B Viruses

Bin Zhou, Yi-Mo Deng, John R Barnes, October M Sessions, Tsui-Wen Chou, Malania Wilson, Thomas J Stark, Michelle Volk, Natalie Spirason, Rebecca A Halpin, Uma Sangumathi Kamaraj, Tao Ding, Timothy B Stockwell, Mirella Salvatore, Elodie Ghedin, Ian G Barr, David E Wentworth

Journal article  |  2017  |  Journal of Clinical Microbiology

Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?

Aeron Hurt, Naomi Komadina, Yi-Mo Deng, Matthew Kaye, Sheena Sullivan, Kanta Subbarao, Ian Barr

Journal article  |  2017  |  Eurosurveillance

Antibody-dependent phagocytosis (ADP) responses following trivalent inactivated influenza vaccination of younger and older adults

Fernanda Ana-Sosa-Batiz, Angus PR Johnston, P Mark Hogarth, Bruce D Wines, Ian Barr, Adam K Wheatley, Stephen J Kent

Journal article  |  2017  |  Vaccine

Ibrutinib may impair serological responses to influenza vaccination

Abby P Douglas, Jason A Trubiano, Ian Barr, Vivian Leung, Monica A Slavin, Constantine S Tam

Journal article  |  2017  |  Haematologica

Rapid evolution of the PB1-F2 virulence protein expressed by human seasonal H3N2 influenza viruses reduces inflammatory responses to infection

Julie McAuley, Yi-Mo Deng, Brad Gilbertson, Charley Mackenzie-Kludas, Ian Barr, Lorena Brown

Journal article  |  2017  |  Virology Journal

Relative incidence and individual-level severity of seasonal influenza A H3N2 compared with 2009 pandemic H1N1

Kin On Kwok, Steven Riley, Ranawaka APM Perera, Vivian WI Wei, Peng Wu, Lan Wei, Daniel KW Chu, Ian G Barr, JS Malik Peiris, Benjamin J Cowling

Journal article  |  2017  |  BMC Infectious Diseases

Assessing the potential pandemic risk of recent avian influenza viruses

Ian G Barr

Journal article  |  2017  |  European Respiratory Journal

CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity

Judy P Hines, Aaron T Smith, Jose P Jacob, Gudrun S Lukat-Rodgers, Ian Barr, Kenton R Rodgers, Feng Guo, Judith N Burstyn

Journal article  |  2016  |  JBIC Journal of Biological Inorganic Chemistry

Influenza C infections in Western Australia and Victoria from 2008 to 2014

Lauren Jelley, Avram Levy, Yi-Mo Deng, Natalie Spirason, Jurissa Lang, Iwona Buettner, Julian Druce, Chris Blyth, Paul Effler, David Smith, Ian G Barr

Journal article  |  2016  |  Influenza and Other Respiratory Viruses

Avian influenza. Why the concern?

Ian G Barr, Frank YK Wong

Journal article  |  2016  |  Microbiology Australia

Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica

Aeron C Hurt, Yvonne CF Su, Malet Aban, Heidi Peck, Hilda Lau, Chantal Baas, Yi-Mo Deng, Natalie Spirason, Patrik Ellstrom, Jorge Hernandez, Bjorn Olsen, Ian G Barr, Dhanasekaran Vijaykrishna, Daniel Gonzalez-Acuna

Journal article  |  2016  |  Journal of Virology

Efficacy of a trivalent influenza vaccine against seasonal strains and against 2009 pandemic H1N1: A randomized, placebo-controlled trial

William JH Mcbride, Walter P Abhayaratna, Ian Barr, Robert Booy, Jonathan Carapetis, Simon Carson, Ferdinandus De Looze, Rod Ellis-Pegler, Leon Heron, Jeff Karraschi, Helen Marshall, Jodie Mcvernon, Terry Nolan, William Rawlinson, Jim Reid, Peter Richmond, Sepehr Shakib, Russell L Basser, Gunter F Hartel, Michael H Lai, et al.

Journal article  |  2016  |  Vaccine

Human Phase 1 trial of low-dose inactivated seasonal influenza vaccine formulated with Advax (TM) delta inulin adjuvant

David L Gordon, Dimitar Sajkov, Yoshikazu Honda-Okubo, Samuel H Wilks, Malet Aban, Ian G Barr, Nikolai Petrovsky

Journal article  |  2016  |  Vaccine

Trivalent and quadrivalent influenza vaccination effectiveness in Australia and South Africa: results from a modelling study

George J Milne, Nilimesh Halder, Joel K Kelso, Ian G Barr, Jocelyn Moyes, Kathleen Kahn, Rhian Twine, Cheryl Cohen

Journal article  |  2016  |  Influenza and Other Respiratory Viruses

What Lies Beneath: Antibody Dependent Natural Killer Cell Activation by Antibodies to Internal Influenza Virus Proteins

Hillary A Vanderven, Fernanda Ana-Sosa-Batiz, Sinthujan Jegaskanda, Steven Rockman, Karen Laurie, Ian Barr, Weisan Chen, Bruce Wines, P Mark Hogarth, Teresa Lambe, Sarah C Gilbert, Matthew S Parsons, Stephen J Kent

Journal article  |  2016  |  EBioMedicine

Influenza-Specific Antibody-Dependent Phagocytosis

Fernanda Ana-Sosa-Batiz, Hillary Vanderven, Sinthujan Jegaskanda, Angus Johnston, Steven Rockman, Karen Laurie, Ian Barr, Patrick Reading, Marit Lichtfuss, Stephen J Kent

Journal article  |  2016  |  PLOS ONE

Characterization of the Localized Immune Response in the Respiratory Tract of Ferrets following Infection with Influenza A and B Viruses

Louise A Carolan, Steve Rockman, Kathryn Borg, Teagan Guarnaccia, Patrick Reading, Jennifer Mosse, Anne Kelso, Ian Barr, Karen L Laurie

Journal article  |  2016  |  Journal of Virology

Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer

Rishi S Kotecha, Ushma D Wadia, Peter Jacoby, Anne L Ryan, Christopher C Blyth, Anthony D Keil, Nicholas G Gottardo, Catherine H Cole, Ian G Barr, Peter C Richmond

Journal article  |  2016  |  Cancer Medicine

Structural and functional characterisation of ferret interleukin-2

Bin Ren, William J McKinstry, Pham Tam, Janet Newman, Daniel S Layton, Andrew G Bean, Zhenjun Chen, Karen L Laurie, Kathryn Borg, Ian G Barr, Timothy E Adams

Journal article  |  2016  |  Developmental & Comparative Immunology

Differential age susceptibility to influenza B/Victoria lineage viruses in the 2015 Australian influenza season

IG Barr, D Vijaykrishna, SG Sullivan

Journal article  |  2016  |  Eurosurveillance

INFLUENZA VIRUSES RECEIVED AND TESTED BY THE MELBOURNE WHO COLLABORATING CENTRE FOR REFERENCE AND RESEARCH ON INFLUENZA ANNUAL REPORT, 2014

Sheena G Sullivan, Michelle K Chow, Ian G Barr, Anne Kelso

Journal article  |  2015  |  Communicable diseases intelligence quarterly report

Interval Between Infections and Viral Hierarchy Are Determinants of Viral Interference Following Influenza Virus Infection in a Ferret Model

Karen L Laurie, Teagan A Guarnaccia, Louise A Carolan, Ada WC Yan, Malet Aban, Stephen Petrie, Pengxing Cao, Jane M Heffernan, Jodie McVernon, Jennifer Mosse, Anne Kelso, James M Mccaw, Ian G Barr

Journal article  |  2015  |  JOURNAL OF INFECTIOUS DISEASES

Zanamivir-resistant influenza viruses with Q136K or Q136R neuraminidase residue mutations can arise during MDCK cell culture creating challenges for antiviral susceptibility monitoring

K Little, S Leang, J Butler, C Baas, B Harrower, J Mosse, IG Barr, AC Hurt

Journal article  |  2015  |  Eurosurveillance

Quantifying relative within-host replication fitness in influenza virus competition experiments

Stephen M Petrie, Jeff Butler, Ian G Barr, Jodie McVernon, Aeron C Hurt, James M McCaw

Journal article  |  2015  |  JOURNAL OF THEORETICAL BIOLOGY

Phylodynamics of H1N1/2009 influenza reveals the transition from host adaptation to immune-driven selection

Yvonne CF Su, Justin Bahl, Udayan Joseph, Ka Man Butt, Heidi A Peck, Evelyn SC Koay, Lynette LE Oon, Ian G Barr, Dhanasekaran Vijaykrishna, Gavin JD Smith

Journal article  |  2015  |  Nature Communications

Innate Immunity and the Inter-exposure Interval Determine the Dynamics of Secondary Influenza Virus Infection and Explain Observed Viral Hierarchies

Pengxing Cao, Ada WC Yan, Jane M Heffernan, Stephen Petrie, Robert G Moss, Louise A Carolan, Teagan A Guarnaccia, Anne Kelso, Ian G Barr, Jodie McVernon, Karen L Laurie, James M McCaw

Journal article  |  2015  |  PLOS COMPUTATIONAL BIOLOGY

Global circulation patterns of seasonal influenza viruses vary with antigenic drift

Trevor Bedford, Steven Riley, Ian G Barr, Shobha Broor, Mandeep Chadha, Nancy J Cox, Rodney S Daniels, C Palani Gunasekaran, Aeron C Hurt, Anne Kelso, Alexander Klimov, Nicola S Lewis, Xiyan Li, John W McCauley, Takato Odagiri, Varsha Potdar, Andrew Rambaut, Yuelong Shu, Eugene Skepner, Derek J Smith, et al.

Journal article  |  2015  |  Nature

A simplified Sanger sequencing method for full genome sequencing of multiple subtypes of human influenza A viruses

Yi-Mo Deng, Natalie Spirason, Pina Iannello, Lauren Jelley, Hilda Lau, Ian G Barr

Journal article  |  2015  |  Journal of Clinical Virology

Influenza viruses with B/Yamagata- and B/Victoria-like neuraminidases are differentially affected by mutations that alter antiviral susceptibility

Rubaiyea Farrukee, Sook-Kwan Leang, Jeff Butler, Raphael TC Lee, Sebastian Maurer-Stroh, Danielle Tilmanis, Sheena Sullivan, Jennifer Mosse, Ian G Barr, Aeron C Hurt

Journal article  |  2015  |  Journal of Antimicrobial Chemotherapy

Cobalt(III) Protoporphyrin Activates the DGCR8 Protein and Can Compensate microRNA Processing Deficiency

Ian Barr, Sara H Weitz, Talia Atkin, PeiKen Hsu, Maria Karayiorgou, Joseph A Gogos, Shimon Weiss, Feng Guo

Journal article  |  2015  |  Chemistry & Biology

Performance of case definitions for influenza surveillance.

L Jiang, VJ Lee, WY Lim, MI Chen, Y Chen, L Tan, RT Lin, YS Leo, I Barr, AR Cook

Journal article  |  2015  |  Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin

Influenza-like illness (ILI) case definitions, such as those from the European Centre for Disease Control and Prevention, World He..

Inter-Seasonal Influenza is Characterized by Extended Virus Transmission and Persistence

Zoe Patterson Ross, Naomi Komadina, Yi-Mo Deng, Natalie Spirason, Heath A Kelly, Sheena G Sullivan, Ian G Barr, Edward C Holmes

Journal article  |  2015  |  PLOS Pathogens

Oseltamivir reduces clinical illness in households in Bangladesh

Ian G Barr, Heath A Kelly

Journal article  |  2015  |  The Lancet Infectious Diseases

Targeting PI3K-p110 alpha Suppresses Influenza Virus Infection in Chronic Obstructive Pulmonary Disease

Alan Chen-Yu Hsu, Malcolm R Starkey, Irwan Hanish, Kristy Parsons, Tatt Jhong Haw, Linda J Howland, Ian Barr, James B Mahony, Paul S Foster, Darryl A Knight, Peter A Wark, Philip M Hansbro

Journal article  |  2015  |  American Journal of Respiratory and Critical Care Medicine

A Novel Video Tracking Method to Evaluate the Effect of Influenza Infection and Antiviral Treatment on Ferret Activity

Ding Yuan Oh, Ian G Barr, Aeron C Hurt

Journal article  |  2015  |  PLOS ONE

Mannan adjuvants intranasally administered inactivated influenza virus in mice rendering low doses inductive of strong serum IgG and IgA in the lung

Owen Proudfoot, Sandra Esparon, Choon-Kit Tang, Karen Laurie, Ian Barr, Geoffrey Pietersz

Journal article  |  2015  |  BMC Infectious Diseases

Hemagglutination inhibiting antibodies and protection against seasonal and pandemic influenza infection

Annette Fox, Quynh Mai Le, Thi Thanh Le, Marcel Wolbers, Le Khanh Hang Nguyen, Quang Thai Pham, Thi Thu Yen Nguyen, Nguyen Minh Hoa Le, Juliet E Bryant, Nhu Duong Tran, Dinh Thoang Dang, Ian G Barr, Heiman Wertheim, Jeremy Farrar, Tran Hien Nguyen, Peter Horby

Journal article  |  2015  |  Journal of Infection

The contrasting phylodynamics of human infuenza B viruses

Dhanasekaran Vijaykrishna, Edward C Holmes, Udayan Joseph, Mathieu Fourment, Yvonne CF Su, Rebecca Halpin, Raphael TC Lee, Yi-Mo Deng, Vithiagaran Gunalan, Xudong Lin, Timothy B Stockwell, Nadia B Fedorova, Bin Zhou, Natalie Spirason, Denise Kuehnert, Veronika Boskova, Tanja Stadler, Anna-Maria Costa, Dominic E Dwyer, Q Sue Huang, et al.

Journal article  |  2015  |  eLife

Performance of case definitions for influenza surveillance

L Jiang, VJ Lee, WY Lim, MI Chen, Y Chen, L Tan, RT Lin, YS Leo, I Barr, AR Cook

Journal article  |  2015  |  Eurosurveillance

Molecular Epidemiology of Influenza A(H1N1) pdm09 Virus among Humans and Swine, Sri Lanka

Harsha KK Perera, Dhanasekaran Vijaykrishna, Akuratiya G Premarathna, Chrishan JS Jayamaha, Geethani Wickramasinghe, Chung L Cheung, Ming F Yeung, Leo LM Poon, Aluthgama KC Perera, Ian G Barr, Yi Guan, Malik Peiris

Journal article  |  2014  |  Emerging Infectious Diseases

Antibody landscapes after influenza virus infection or vaccination

JM Fonville, SH Wilks, SL James, A Fox, M Ventresca, M Aban, L Xue, TC Jones, NMH Le, QT Pham, ND Tran, Y Wong, A Mosterin, LC Katzelnick, D Labonte, TT Le, G van der Net, E Skepner, CA Russell, TD Kaplan, et al.

Journal article  |  2014  |  Science

Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturing

Ruben O Donis, i-Mei Chen, C Todd Davis, Angie Foust, M Jaber Hossain, Adam Johnson, Alexander Klimov, Rosette Loughlin, Xiyan Xu, Theodore Tsai, Simone Blayer, Heidi Trusheim, Tony Colegate, John Fox, Beverly Taylor, Althaf Hussain, Ian Barr, Chantal Baas, Jaap Louwerens, Ed Geuns, et al.

Journal article  |  2014  |  Vaccine

Influenza Gain-of-Function Experiments: Their Role in Vaccine Virus Recommendation and Pandemic Preparedness

S Schultz-Cherry, RJ Webby, RG Webster, A Kelso, IG Barr, JW McCauley, RS Daniels, D Wang, Y Shu, E Nobusawa, S Itamura, M Tashiro, Y Harada, S Watanabe, T Odagiri, Z Ye, G Grohmann, R Harvey, O Engelhardt, D Smith, et al.

Journal article  |  2014  |  mBio

Epidemiological and Virological Characteristics of Influenza Viruses Circulating in Cambodia from 2009 to 2011

Srey Viseth Horm, Sek Mardy, Sareth Rith, Sovann Ly, Seng Heng, Sirenda Vong, Paul Kitsutani, Vannra Ieng, Arnaud Tarantola, Sowath Ly, Borann Sar, Nora Chea, Buth Sokhal, Ian Barr, Anne Kelso, Paul F Horwood, Ans Timmermans, Aeron Hurt, Chanthap Lon, David Saunders, et al.

Journal article  |  2014  |  PLOS ONE

Evaluation of oseltamivir prophylaxis regimens for reducing influenza virus infection, transmission and disease severity in a ferret model of household contact

Ding Yuan Oh, Sue Lowther, James M McCaw, Sheena G Sullivan, Sook-Kwan Leang, Jessica Haining, Rachel Arkinstall, Anne Kelso, Jodie Mcvernon, Ian G Barr, Deborah Middleton, Aeron C Hurt

Journal article  |  2014  |  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

TaqMan real time RT-PCR assays for detecting ferret innate and adaptive immune responses

Louise A Carolan, Jeff Butler, Steve Rockman, Teagan Guarnaccia, Aeron C Hurt, Patrick Reading, Anne Kelso, Ian Barr, Karen L Laurie

Journal article  |  2014  |  Journal of Virological Methods

WHO recommendations for the viruses used in the 2013-2014 Northern Hemisphere influenza vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from October 2012 to January 2013

Ian G Barr, Colin Russell, Terry G Besselaar, Nancy J Cox, Rod S Daniels, Ruben Donis, Othmar G Engelhardt, Gary Grohmann, Shigeyuki Itamura, Anne Kelso, John McCauley, Takato Odagiri, Stacey Schultz-Cherry, Yuelong Shu, Derek Smith, Masato Tashiro, Dayan Wang, Richard Webby, Xiyan Xu, Zhiping Ye, et al.

Journal article  |  2014  |  Vaccine

Rate of decline of antibody titers to pandemic influenza A (H1N1-2009) by hemagglutination inhibition and virus microneutralization assays in a cohort of seroconverting adults in Singapore

Jung Pu Hsu, Xiahong Zhao, Mark I-Cheng Chen, Alex R Cook, Vernon Lee, Wei Yen Lim, Linda Tan, Ian G Barr, Lili Jiang, Chyi Lin Tan, Meng Chee Phoon, Lin Cui, Raymond Lin, Yee Sin Leo, Vincent T Chow

Journal article  |  2014  |  BMC Infectious Diseases

Detection of Evolutionarily Distinct Avian Influenza A Viruses in Antarctica

Aeron C Hurt, Dhanasekaran Vijaykrishna, Jeffrey Butler, Chantal Baas, Sebastian Maurer-Stroh, M Carolina Silva-de-la-Fuente, Gonzalo Medina-Vogel, Bjorn Olsen, Anne Kelso, Ian G Barr, Daniel Gonzalez-Acuna

Journal article  |  2014  |  MBIO

Universal Influenza B Virus Genomic Amplification Facilitates Sequencing, Diagnostics, and Reverse Genetics

Bin Zhou, Xudong Lin, Wei Wang, Rebecca A Halpin, Jayati Bera, Timothy B Stockwell, Ian G Barr, David E Wentworth

Journal article  |  2014  |  Journal of Clinical Microbiology

Hospital capacity and management preparedness for pandemic influenza in Victoria

Ben Dewar, Ian Barr, Priscilla Robinson

Journal article  |  2014  |  Australian and New Zealand Journal of Public Health

Estimating the Fitness Advantage Conferred by Permissive Neuraminidase Mutations in Recent Oseltamivir-Resistant A(H1N1) pdm09 Influenza Viruses

Jeff Butler, Kathryn A Hooper, Stephen Petrie, Raphael Lee, Sebastian Maurer-Stroh, Lucia Reh, Teagan Guarnaccia, Chantal Baas, Lumin Xue, Sophie Vitesnik, Sook-Kwan Leang, Jodie McVernon, Anne Kelso, Ian G Barr, James M McCaw, Jesse D Bloom, Aeron C Hurt

Journal article  |  2014  |  PLOS PATHOGENS

Seroprevalence of antibody to influenza A(H1N1) pdm09 attributed to vaccination or infection, before and after the second (2010) pandemic wave in Australia

Jodie McVernon, Karen Laurie, Helen Faddy, David Irving, Terry Nolan, Ian Barr, Anne Kelso

Journal article  |  2014  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Peramivir and laninamivir susceptibility of circulating influenza A and B viruses

Sook-Kwan Leang, Simon Kwok, Sheena G Sullivan, Sebastian Maurer-Stroh, Anne Kelso, Ian G Barr, Aeron C Hurt

Journal article  |  2014  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Processing of microRNA primary transcripts requires heme in mammalian cells

Sara H Weitz, Ming Gong, Ian Barr, Shimon Weiss, Feng Guo

Journal article  |  2014  |  Proceedings of the National Academy of Sciences

Primary MicroRNA Processing Assay Reconstituted Using Recombinant Drosha and DGCR8

Ian Barr, Feng Guo

Journal article  |  2014  |  Methods in Molecular Biology

Primary microRNA processing assay reconstituted using recombinant Drosha and DGCR8.

Ian Barr, Feng Guo

Journal article  |  2014  |  Methods in Molecular Biology

In animals, the Microprocessor complex cleaves primary transcripts of microRNAs (pri-miRNAs) to produce precursor microRNAs in the..

Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution

Bjorn F Koel, David F Burke, Theo M Bestebroer, Stefan van der Vliet, Gerben CM Zondag, Gaby Vervaet, Eugene Skepner, Nicola S Lewis, Monique IJ Spronken, Colin A Russell, Mikhail Y Eropkin, Aeron C Hurt, Ian G Barr, Jan C de Jong, Guus F Rimmelzwaan, Albert DME Osterhaus, Ron AM Fouchier, Derek J Smith

Journal article  |  2013  |  Science

Factors influencing infection by pandemic influenza A (H1N1)pdm09 over three epidemic waves in Singapore

Mark IC Chen, Alex R Cook, Wei Yen Lim, Raymond Lin, Lin Cui, Ian G Barr, Anne Kelso, Vincent T Chow, Yee Sin Leo, Jung Pu Hsu, Rob Shaw, Serene Chew, Joe Kwan Yap, Meng Chee Phoon, Hiromi WL Koh, Huili Zheng, Linda Tan, Vernon J Lee

Journal article  |  2013  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Progressive emergence of an oseltamivir-resistant A (H3N2) virus over two courses of oseltamivir treatment in an immunocompromised paediatric patient

Aeron C Hurt, Sook Kwan Leang, Karin Tiedemann, Jeff Butler, Francoise Mechinaud, Anne Kelso, Peter Downie, Ian G Barr

Journal article  |  2013  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Age-Associated Cross-reactive Antibody-Dependent Cellular Cytotoxicity Toward 2009 Pandemic Influenza A Virus Subtype H1N1

Sinthujan Jegaskanda, Karen L Laurie, Thakshila H Amarasena, Wendy R Winnall, Marit Kramski, Robert De Rose, Ian G Barr, Andrew G Brooks, Patrick C Reading, Stephen J Kent

Journal article  |  2013  |  JOURNAL OF INFECTIOUS DISEASES

The Recent Establishment of North American H10 Lineage Influenza Viruses in Australian Wild Waterfowl and the Evolution of Australian Avian Influenza Viruses

Dhanasekaran Vijaykrishna, Yi-Mo Deng, Yvonne CF Su, Mathieu Fourment, Pina Iannello, George G Arzey, Philip M Hansbro, K Edla Arzey, Peter D Kirkland, Simone Warner, Kim O'Riley, Ian G Barr, Gavin JD Smith, Aeron C Hurt

Journal article  |  2013  |  Journal of Virology

The use of pyrosequencer-generated sequence-signatures to identify the influenza B-lineage and the subclade of the B/Yamataga-lineage viruses from currently circulating human influenza B viruses

Yi-Mo Deng, Pina Iannello, Natalie Caldwell, Lauren Jelley, Naomi Komadina, Chantal Baas, Anne Kelso, Ian G Barr

Journal article  |  2013  |  Journal of Clinical Virology

Seroprevalence of Seasonal and Pandemic Influenza A in Kuala Lumpur, Malaysia in 2008-2010

I-Ching Sam, Robert Shaw, Yoke-Fun Chan, Poh-Sim Hooi, Aeron C Hurt, Ian G Barr

Journal article  |  2013  |  Journal of Medical Virology

Double dose oseltamivir for severe influenza-does it help?

Ian G Barr, Aeron C Hurt

Journal article  |  2013  |  BMJ

A comparison of rapid point-of-care tests for the detection of avian influenza A(H7N9) virus, 2013

C Baas, IG Barr, RA Fouchier, A Kelso, AC Hurt

Journal article  |  2013  |  Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin

Antigenic Drift of the Pandemic 2009 A(H1N1) Influenza Virus in a Ferret Model

Teagan Guarnaccia, Louise A Carolan, Sebastian Maurer-Stroh, Raphael TC Lee, Emma Job, Patrick C Reading, Stephen Petrie, James M McCaw, Jodie McVernon, Aeron C Hurt, Anne Kelso, Jennifer Mosse, Ian G Barr, Karen L Laurie

Journal article  |  2013  |  PLOS PATHOGENS

Development of an enzyme-linked immunoassay for the quantitation of influenza haemagglutinin: an alternative method to single radial immunodiffusion

Jesse Bodle, Erin E Verity, Chi Ong, Kirsten Vandenberg, Robert Shaw, Ian G Barr, Steven Rockman

Journal article  |  2013  |  Influenza and Other Respiratory Viruses

Neuraminidase-Inhibiting Antibody Is a Correlate of Cross-Protection against Lethal H5N1 Influenza Virus in Ferrets Immunized with Seasonal Influenza Vaccine

Steven Rockman, Lorena E Brown, Ian G Barr, Brad Gilbertson, Sue Lowther, Anatoly Kachurin, Olga Kachurina, Jessica Klippel, Jesse Bodle, Martin Pearse, Deborah Middleton

Journal article  |  2013  |  Journal of Virology

Impaired dendritic cell maturation in response to pandemic H1N109 influenza virus

Ruth Chin, Linda Earnest-Silviera, Claire L Gordon, Karen Olsen, Ian Barr, Lorena E Brown, David C Jackson, Joseph Torresi

Journal article  |  2013  |  Journal of Clinical Virology

Influenza antiviral resistance in the Asia-Pacific region during 2011

Sook-Kwan Leang, Yi-Mo Deng, Robert Shaw, Natalie Caldwell, Pina Iannello, Naomi Komadina, Philippe Buchy, Malinee Chittaganpitch, Dominic E Dwyer, Peter Fagan, Ann-Claire Gourinat, Frances Hammill, Paul F Horwood, QS Huang, Peng Kei IP, Lance Jennings, Alison Kesson, Tuckweng Kok, Jacob L Kool, Avram Levy, et al.

Journal article  |  2013  |  Antiviral Research

Teacher led school-based surveillance can allow accurate tracking of emerging infectious diseases - evidence from serial cross-sectional surveys of febrile respiratory illness during the H1N1 2009 influenza pandemic in Singapore

Shu E Soh, Alex R Cook, Mark IC Chen, Vernon J Lee, Jeffery L Cutter, Vincent TK Chow, Nancy WS Tee, Raymond TP Lin, Wei-Yen Lim, Ian G Barr, Cui Lin, Meng Chee Phoon, Li Wei Ang, Sunil K Sethi, Chia Yin Chong, Lee Gan Goh, Denise LM Goh, Paul A Tambyah, Koh Cheng Thoon, Yee Sin Leo, et al.

Journal article  |  2012  |  BMC Infectious Diseases

Influenza antivirals and resistance: the next 10 years?

Aeron C Hurt, Jeff Butler, Anne Kelso, Ian G Barr

Journal article  |  2012  |  Expert Review of Anti-infective Therapy

WHO recommendations for the viruses to be used in the 2012 Southern Hemisphere Influenza Vaccine: Epidemiology, antigenic and genetic characteristics of influenza A(H1N1)pdm09, A(H3N2) and B influenza viruses collected from February to September 2011

Alexander I Klimov, Rebecca Garten, Colin Russell, Ian G Barr, Terry G Besselaar, Rod Daniels, Othmar G Engelhardt, Gary Grohmann, Shigeyuki Itamura, Anne Kelso, John McCauley, Takato Odagiri, Derek Smith, Masato Tashiro, Xiyan Xu, Richard Webby, Dayan Wang, Zhiping Ye, Yuelong Shu, Wenqing Zhang, et al.

Journal article  |  2012  |  Vaccine

Characteristics of a Widespread Community Cluster of H275Y Oseltamivir-Resistant A (H1N1)pdm09 Influenza in Australia

AC Hurt, K Hardie, NJ Wilson, YM Deng, M Osbourn, SK Leang, RTC Lee, P Iannello, N Gehrig, R Shaw, P Wark, N Caldwell, RC Givney, L Xue, S Maurer-Stroh, DE Dwyer, B Wang, DW Smith, A Levy, R Booy, et al.

Journal article  |  2012  |  The Journal of Infectious Diseases

Dimerization and Heme Binding Are Conserved in Amphibian and Starfish Homologues of the microRNA Processing Protein DGCR8

Rachel Senturia, Arthur Laganowsky, Ian Barr, Brooke D Scheidemantle, Feng Guo

Journal article  |  2012  |  PLoS ONE

Epidemiological and Virological Characteristics of Influenza in the Western Pacific Region of the World Health Organization, 2006-2010

Ian Barr, Aeron Hurt, Anne Kelso, Patrick Reading, Sovann Ly, Heng Seng, Philippe Buchy, Sam An Ung, Yuelong Shu, Cuiling Xu, Zhen Xu, Dayan Wang, Mike Kama, Prem Singh, Seiichiro Fujisaki, Takato Odagiri, Masato Tashiro, Sibounhom Archkhawongs, Bouaphanh Khamphaphongphanh, Phengta Vongphrachanh, et al.

Journal article  |  2012  |  PLoS ONE

Control of pandemic (H1N1) 2009 influenza virus infection of ferret lungs by non-adjuvant-containing pandemic and seasonal vaccines

Steven Rockman, Deborah J Middleton, Martin J Pearse, Ian G Barr, Sue Lowther, Lorena E Brown

Journal article  |  2012  |  Vaccine

Influenza Virus A (H10N7) in Chickens and Poultry Abattoir Workers, Australia

George G Arzey, Peter D Kirkland, K Edla Arzey, Melinda Frost, Patrick Maywood, Stephen Conaty, Aeron C Hurt, Yi-Mo Deng, Pina Iannello, Ian Barr, Dominic E Dwyer, Mala Ratnamohan, Kenneth McPhie, Paul Selleck

Journal article  |  2012  |  Emerging Infectious Diseases

Transmission of influenza A(H1N1) 2009 pandemic viruses in Australian swine

Yi-Mo Deng, Pina Iannello, Ina Smith, James Watson, Ian G Barr, Peter Daniels, Naomi Komadina, Bruce Harrower, Frank YK Wong

Journal article  |  2012  |  Influenza and Other Respiratory Viruses

Identification of a cis-acting element that localizes mRNA to synapses

Elliott J Meer, Dan Ohtan Wang, Sangmok Kim, Ian Barr, Feng Guo, Kelsey C Martin

Journal article  |  2012  |  Proceedings of the National Academy of Sciences

Critical Role of Constitutive Type I Interferon Response in Bronchial Epithelial Cell to Influenza Infection

Alan C-Y Hsu, Kristy Parsons, Ian Barr, Sue Lowther, Deborah Middleton, Philip M Hansbro, Peter AB Wark

Journal article  |  2012  |  PLoS ONE

Rapid generation of pandemic influenza virus vaccine candidate strains using synthetic DNA

Erin E Verity, Sarina Camuglia, Catherine T Agius, Chi Ong, Robert Shaw, Ian Barr, Deborah Middleton, Steven Rockman

Journal article  |  2012  |  Influenza and Other Respiratory Viruses

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

Ian Barr, Aaron T Smith, Yanqiu Chen, Rachel Senturia, Judith N Burstyn, Feng Guo

Journal article  |  2012  |  Proceedings of the National Academy of Sciences

The Coming Era of Quadrivalent Human Influenza Vaccines Who will Benefit?

Ian G Barr, Lauren L Jelley

Journal article  |  2012  |  Drugs

Mutations I117V and I117M and Oseltamivir Sensitivity of Pandemic (H1N1) 2009 Viruses

Aeron C Hurt, Sook Kwan Leang, David J Speers, Ian G Barr, Sebastian Maurer-Stroh

Journal article  |  2012  |  Emerging Infectious Diseases

No association between mannose-binding lectin deficiency and H1N1 2009 infection observed during the first season of this novel pandemic influenza virus

Damon P Eisen, Caroline Marshall, Melinda M Dean, Joe Sasadeusz, Michael Richards, Kirsty Buising, Allen Cheng, Paul DR Johnson, Ian G Barr, Emma S McBryde

Journal article  |  2011  |  Human Immunology

Rapid Detection and Subtyping of Human Influenza A Viruses and Reassortants by Pyrosequencing

Yi-Mo Deng, Natalie Caldwell, Ian G Barr

Journal article  |  2011  |  PLoS ONE

Comparability of Different Methods for Estimating Influenza Infection Rates Over a Single Epidemic Wave

Vernon J Lee, Mark I Chen, Jonathan Yap, Jocelyn Ong, Wei-Yen Lim, Raymond TP Lin, Ian Barr, Jimmy BS Ong, Tze Minn Mak, Lee Gan Goh, Yee Sin Leo, Paul M Kelly, Alex R Cook

Journal article  |  2011  |  American Journal of Epidemiology

Risk Factors for Pandemic (H1N1) 2009 Seroconversion among Adults, Singapore, 2009

Wei-Yen Lim, Cynthia HJ Chen, Yi Ma, Mark IC Chen, Vernon JM Lee, Alex R Cook, Linda WL Tan, Norberto Flores Tabo, Ian Barr, Lin Cui, Raymond TP Lin, Yee Sin Leo, Kee Seng Chia

Journal article  |  2011  |  Emerging Infectious Diseases

VereFlu (TM): an integrated multiplex RT-PCR and microarray assay for rapid detection and identification of human influenza A and B viruses using lab-on-chip technology

Jeanette Teo, Patrizia Di Pietro, Floriana San Biagio, Monica Capozzoli, Yi-Mo Deng, Ian Barr, Natalie Caldwell, Kian-Leong Ong, Mitsuharu Sato, Rosemary Tan, Raymond Lin

Journal article  |  2011  |  Archives of Virology

Rapid Detection of the H275Y Oseltamivir Resistance Mutation in Influenza A/H1N1 2009 by Single Base Pair RT-PCR and High-Resolution Melting

Steven YC Tong, Farshid Dakh, Aeron C Hurt, Yi-Mo Deng, Kevin Freeman, Peter K Fagan, Ian G Barr, Philip M Giffard

Journal article  |  2011  |  PLoS ONE

Increased detection in Australia and Singapore of a novel influenza A(H1N1) 2009 variant with reduced oseltamivir and zanamivir sensitivity due to a S247N neuraminidase mutation

AC Hurt, RT Lee, SK Leang, L Cui, YM Deng, SP Phuah, N Caldwell, K Freeman, N Komadina, D Smith, D Speers, A Kelso, RT Lin, S Maurer-Stroh, IG Barr

Journal article  |  2011  |  Eurosurveillance

Human Influenza Is More Effective than Avian Influenza at Antiviral Suppression in Airway Cells

Alan Chen-Yu Hsu, Ian Barr, Philip M Hansbro, Peter A Wark

Journal article  |  2011  |  American Journal of Respiratory Cell and Molecular Biology

Pandemic (H1N1) 2009 Risk for Frontline Health Care Workers

Caroline Marshall, Anne Kelso, Emma McBryde, Ian G Barr, Damon P Eisen, Joe Sasadeusz, Kirsty Buising, Allen C Cheng, Paul Johnson, Michael Richards

Journal article  |  2011  |  EMERGING INFECTIOUS DISEASES

DiGeorge Critical Region 8 (DGCR8) Is a Double-cysteine-ligated Heme Protein

Ian Barr, Aaron T Smith, Rachel Senturia, Yanqiu Chen, Brooke D Scheidemantle, Judith N Burstyn, Feng Guo

Journal article  |  2011  |  Journal of Biological Chemistry

Concurrent Influenza and Shigellosis Outbreaks, Papua New Guinea, 2009

Alexander Rosewell, Rosheila Dagina, Manoj Murhekar, Berry Ropa, Enoch Posanai, Samir Dutta, Ian Barr, Glen Mola, Anthony Zwi, C Raina MacIntyre

Journal article  |  2011  |  Emerging Infectious Diseases

A comparison of pyrosequencing and neuraminidase inhibition assays for the detection of oseltamivir-resistant pandemic influenza A(H1N1) 2009 viruses

Yi-Mo Deng, Natalie Caldwell, Aeron Hurt, Tim Shaw, Anne Kelso, Glenys Chidlow, Simon Williams, David Smith, Ian Barr

Journal article  |  2011  |  Antiviral Research

Oseltamivir-resistant influenza viruses circulating during the first year of the influenza A(H1N1)2009 pandemic in the Asia-Pacific region, March 2009 to March 2010

AC Hurt, YM Deng, J Ernest, N Caldwell, L Leang, P Iannello, N Komadina, R Shaw, D Smith, DE Dwyer, AR Tramontana, RT Lin, K Freeman, A Kelso, IG Barr

Journal article  |  2011  |  Eurosurveillance

Incidence of pandemic (H1N1) 2009 influenza infection in children and pregnant women during the 2009 influenza season in Western Australia - a seroprevalence study

Gary K Dowse, David W Smith, Heath Kelly, Ian Barr, Karen L Laurie, Anthony R Jones, Anthony D Keil, Paul Effler

Journal article  |  2011  |  Medical Journal of Australia

Limited novel influenza A (H1N1) 09 infection in travelling high-school tour group

Janine Mardani, Lester Calder, Karen Laurie, Ian Barr, Anne Kelso, Nicholas Jones

Journal article  |  2011  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Absence of cross-reactive antibodies to influenza A (H1N1) 2009 before and after vaccination with 2009 Southern Hemisphere seasonal trivalent influenza vaccine in children aged 6 months-9 years: a prospective study

Jodie McVernon, Karen Laurie, Ian Barr, Anne Kelso, Maryanne Skeljo, Terry Nolan

Journal article  |  2011  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Comparison of the incidence of influenza in relation to climate factors during 2000-2007 in five countries.

Julian W Tang, Florence YL Lai, P Nymadawa, Yi-Mo Deng, Mala Ratnamohan, Martin Petric, Tze Ping Loh, Nancy WS Tee, Dominic E Dwyer, Ian G Barr, Felix YW Wong

Journal article  |  2010  |  Journal of Medical Virology

Relatively few international comparisons of the incidence of influenza related to climate parameters have been performed, particul..

Effectiveness of Public Health Measures in Mitigating Pandemic Influenza Spread: A Prospective Sero-Epidemiological Cohort Study

Vernon J Lee, Jonathan Yap, Alex R Cook, Mark I Chen, Joshua K Tay, Ian Barr, Anne Kelso, Boon Huan Tan, Jin Phang Loh, Raymond Lin, Lin Cui, Paul M Kelly, Yee Sin Leo, Kee Seng Chia, Wee Lee Kang, Paul A Tambyah, Benjamin Seet

Journal article  |  2010  |  The Journal of Infectious Diseases

A new pandemic influenza A(H1N1) genetic variant predominated in the winter 2010 influenza season in Australia, New Zealand and Singapore.

IG Barr, L Cui, N Komadina, RT Lee, RT Lin, Y Deng, N Caldwell, R Shaw, S Maurer-Stroh

Journal article  |  2010  |  Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin

Pandemic H1N1 influenza virus is of global health concern and is currently the predominant influenza virus subtype circulating in ..

Seroprevalence of 2009 pandemic influenza A(H1N1) virus in Australian blood donors, October - December 2009

J McVernon, K Laurie, T Nolan, R Owen, D Irving, H Capper, C Hyland, H Faddy, L Carolan, I Barr, A Kelso

Journal article  |  2010  |  Eurosurveillance

Multiple Infections with Seasonal Influenza A Virus Induce Cross-Protective Immunity against A(H1N1) Pandemic Influenza Virus in a Ferret Model

Karen L Laurie, Louise A Carolan, Deborah Middleton, Sue Lowther, Anne Kelso, Ian G Barr

Journal article  |  2010  |  The Journal of Infectious Diseases

Risk factors for pandemic (H1N1) 2009 virus seroconversion among hospital staff, Singapore.

Mark IC Chen, Vernon JM Lee, Ian Barr, Cui Lin, Rachelle Goh, Caroline Lee, Baldev Singh, Jessie Tan, Wei Yen Lim, Alex R Cook, Brenda Ang, Angela Chow, Boon Huan Tan, Jimmy Loh, Robert Shaw, Kee Seng Chia, Raymond TP Lin, Yee Sin Leo

Journal article  |  2010  |  Emerging Infectious Diseases

We describe incidence and risk factors for pandemic (H1N1) 2009 virus infection in healthcare personnel during the June-September ..

Assessing the Viral Fitness of Oseltamivir-Resistant Influenza Viruses in Ferrets, Using a Competitive-Mixtures Model

Aeron C Hurt, Siti Sarah Nor'e, James M McCaw, Helen R Fryer, Jennifer Mosse, Angela R McLean, Ian G Barr

Journal article  |  2010  |  Journal of Virology

Assessing the development of oseltamivir and zanamivir resistance in A(H5N1) influenza viruses using a ferret model

Aeron C Hurt, Sue Lowther, Deborah Middleton, Ian G Barr

Journal article  |  2010  |  Antiviral Research

Australia's notifiable disease status, 2008: annual report of the National Notifiable Diseases Surveillance System.

undefined NNDSS Annual Report Writing Group, Leah Newman, Stefan Stirzaker, Dougald Knuckey, Kate Robinson, Jennie Hood, Katrina Knope, Gerard Fitzsimmons, Susan Barker, Nicolee Martin, Samantha Siripol, Indra Gajanayake, Marlena Kaczmarek, Ian Barr, Aurysia Hii, Ruth Foxwell, Rhonda Owen, Conan Liu, Phil Wright, Lance Sanders, et al.

Journal article  |  2010  |  Communicable diseases intelligence

In 2008, 65 communicable diseases and conditions were nationally notifiable in Australia. States and territories reported a total ..

Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study.

Mark I Chen, Ian G Barr, Gerald CH Koh, Vernon J Lee, Caroline PS Lee, Robert Shaw, Cui Lin, Jonathan Yap, Alex R Cook, Boon Huan Tan, Jin Phang Loh, Timothy Barkham, Vincent TK Chow, Raymond TP Lin, Yee-Sin Leo

Journal article  |  2010  |  PLoS ONE

BACKGROUND: We describe the serological response following H1N1-2009 influenza A infections confirmed by reverse-transcriptase pol..

A lower than expected adult Victorian community attack rate for pandemic (H1N1) 2009 (Australian and New Zealand Journal of Public Health (2010) 34 (228-231))

N Grills, LS Piers, I Barr, LM Vaughan, R Lester, DJ Magliano, JE Shaw, JA Carnie

Journal article  |  2010  |  Australian and New Zealand Journal of Public Health

Seroconversion and asymptomatic infections during oseltamivir prophylaxis against Influenza A H1N1 2009

Vernon J Lee, Jonathan Yap, Joshua K Tay, Ian Barr, Qiuhan Gao, Hanley J Ho, Boon Huan Tan, Paul M Kelly, Paul A Tambyah, Anne Kelso, Mark I Chen

Journal article  |  2010  |  BMC INFECTIOUS DISEASES

A lower than expected adult Victorian community attack rate for pandemic (H1N1) 2009

Nathan Grills, Leonard S Piers, Ian Barr, Loretta M Vaughan, Rosemary Lester, Dianna J Magliano, Jonathan E Shaw, John A Carnie

Journal article  |  2010  |  Australian and New Zealand Journal of Public Health

Transmission of pandemic A/H1N1 2009 influenza on passenger aircraft: retrospective cohort study

Michael G Baker, Craig N Thornley, Clair Mills, Sally Roberts, Shanika Perera, Julia Peters, Anne Kelso, Ian Barr, Nick Wilson

Journal article  |  2010  |  BMJ

Influenza Outbreaks during World Youth Day 2008 Mass Gathering

Christopher C Blyth, Hong Foo, Sebastiaan J van Hal, Aeron C Hurt, Ian G Barr, Kenneth McPhie, Paul K Armstrong, William D Rawlinson, Vicky Sheppeard, Stephen Conaty, Michael Staff, Dominic E Dwyer

Journal article  |  2010  |  Emerging Infectious Diseases

Cross-reactive antibodies to pandemic (H1N1) 2009 virus, Singapore.

Julian W Tang, Paul A Tambyah, Annelies Wilder-Smith, Kim Yoong Puong, Robert Shaw, Ian G Barr, Kwai Peng Chan

Journal article  |  2010  |  Emerging Infectious Diseases

2009 Influenza A(H1N1) Seroconversion Rates and Risk Factors Among Distinct Adult Cohorts in Singapore

Mark IC Chen, Vernon JM Lee, Wei-Yen Lim, Ian G Barr, Raymond TP Lin, Gerald CH Koh, Jonathan Yap, Lin Cui, Alex R Cook, Karen Laurie, Linda WL Tan, Boon Huan Tan, Jimmy Loh, Robert Shaw, Chris Durrant, Vincent TK Chow, Anne Kelso, Kee Seng Chia, Yee Sin Leo

Journal article  |  2010  |  JAMA

Development and comparison of molecular assays for the rapid detection of the pandemic influenza A (H1N1) 2009 virus.

Wai-Yip Lam, Ting-Fan Leung, Nelson Lee, Jo LK Cheung, Apple CM Yeung, Yolanda II Ho, Rickjason CW Chan, Kitty SC Fung, Ian G Barr, David SC Hui, Joseph JY Sung, Paul KS Chan

Journal article  |  2010  |  Journal of Medical Virology

Human infection with the novel pandemic influenza A (H1N1) virus was first identified in April 2009. Two months later, the World H..

Annual report of the National Influenza Surveillance Scheme, 2008.

Marlena Kaczmarek, Rhonda Owen, Ian G Barr

Journal article  |  2010  |  Communicable diseases intelligence

The 2008 influenza season was moderate overall, with fewer laboratory-confirmed cases and influenza-like illness (ILI) presentatio..

Epidemiological, antigenic and genetic characteristics of seasonal influenza A(H1N1), A(H3N2) and B influenza viruses: Basis for the WHO recommendation on the composition of influenza vaccines for use in the 2009-2010 Northern Hemisphere season

Ian G Barr, John McCauley, Nancy Cox, Rod Daniels, Othmar G Engelhardt, Keiji Fukuda, Gary Grohmann, Alan Hay, Anne Kelso, Alexander Klimov, Takato Odagiri, Derek Smith, Colin Russell, Masato Tashiro, Richard Webby, John Wood, Zhiping Ye, Wenqing Zhang

Journal article  |  2010  |  Vaccine

Large trials confirm immunogenicity of H1N1 vaccines.

Heath Kelly, Ian Barr

Journal article  |  2010  |  The Lancet

A new pandemic influenza A(H1N1) genetic variant predominated in the winter 2010 influenza season in Australia, New Zealand and Singapore

IG Barr, L Cui, N Komadina, RT Lee, RT Lin, Y Deng, N Caldwell, R Shaw, S Maurer-Stroh

Journal article  |  2010  |  Eurosurveillance

Seroprevalence of 2009 pandemic influenza a (H1N1) virus in Australian blood donors, October - December 2009

J Mcvernon, K Laurie, T Nolan, R Owen, D Irving, H Capper, C Hyland, H Faddy, L Carolan, I Barr, A Kelso

Journal article  |  2010  |  Eurosurveillance

Zanamivir-Resistant Influenza Viruses with a Novel Neuraminidase Mutation

Aeron C Hurt, Jessica K Holien, Michael Parker, Anne Kelso, Ian G Barr

Journal article  |  2009  |  Journal of Virology

In Vitro Generation of Neuraminidase Inhibitor Resistance in A(H5N1) Influenza Viruses

Aeron C Hurt, Jessica K Holien, Ian G Barr

Journal article  |  2009  |  Antimicrobial Agents and Chemotherapy

High proportion of influenza B characterises the 2008 influenza season in Victoria.

Kristina A Grant, Kylie Carville, James E Fielding, Ian G Barr, Michaela A Riddell, Thomas Tran, Heath A Kelly

Journal article  |  2009  |  Communicable diseases intelligence

The 2008 influenza season in Victoria was distinctive because of the increased proportion of influenza-like illness (ILI) cases du..

Evaluation of Vaccines for H5N1 Influenza Virus in Ferrets Reveals the Potential for Protective Single-Shot Immunization

Deborah Middleton, Steven Rockman, Martin Pearse, Ian Barr, Sue Lowther, Jessica Klippel, David Ryan, Lorena Brown

Journal article  |  2009  |  Journal of Virology

Performance of influenza rapid point-of-care tests in the detection of swine lineage A(H1N1) influenza viruses

Aeron C Hurt, Chantal Baas, Yi-Mo Deng, Sally Roberts, Anne Kelso, Ian G Barr

Journal article  |  2009  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa

Aeron C Hurt, Joanne Ernest, Yi-Mo Deng, Pina Iannello, Terry G Besselaar, Chris Birch, Philippe Buchy, Malinee Chittaganpitch, Shu-Chun Chiu, Dominic Dwyer, Aurelie Guigon, Bruce Harrower, Ip Peng Kei, Tuckweng Kok, Cui Lin, Ken McPhie, Apandi Mohd, Remigio Olveda, Tony Panayotou, William Rawlinson, et al.

Journal article  |  2009  |  Antiviral Research

Combined NKT cell activation and influenza virus vaccination boosts memory CTL generation and protective immunity

Carole Guillonneau, Justine D Mintern, Francois-Xavier Hubert, Aeron C Hurt, Gurdyal S Besra, Steven Porcelli, Ian G Barr, Peter C Doherty, Dale I Godfrey, Stephen J Turner

Journal article  |  2009  |  Proceedings of the National Academy of Sciences of the United States of America

Response of Porphyromonas gingivalis to Heme Limitation in Continuous Culture

Stuart G Dashper, Ching-Seng Ang, Paul D Veith, Helen L Mitchell, Alvin WH Lo, Christine A Seers, Katrina A Walsh, Nada Slakeski, Dina Chen, J Patricia Lissel, Catherine A Butler, Neil M O'Brien-Simpson, Ian G Barr, Eric C Reynolds

Journal article  |  2009  |  Journal of Bacteriology

Efficacy of Soap and Water and Alcohol-Based Hand-Rub Preparations against Live H1N1 Influenza Virus on the Hands of Human Volunteers

M Lindsay Grayson, Sharmila Melvani, Julian Druce, Ian G Barr, Susan A Ballard, Paul DR Johnson, Tasoula Mastorakos, Christopher Birch

Journal article  |  2009  |  Clinical Infectious Diseases

Estimation of influenza vaccine effectiveness from routine surveillance data.

Heath Kelly, Kylie Carville, Kristina Grant, Peter Jacoby, Thomas Tran, Ian Barr

Journal article  |  2009  |  PLoS ONE

BACKGROUND: Influenza vaccines are reviewed each year, and often changed, in an effort to maintain their effectiveness against dri..

Oseltamivir Resistance and the H274Y Neuraminidase Mutation in Seasonal, Pandemic and Highly Pathogenic Influenza Viruses

Aeron C Hurt, Jessica K Holien, Michael W Parker, Ian G Barr

Journal article  |  2009  |  Drugs

Evidence of a novel RNA secondary structure in the coding region of HIV-1 pol gene.

Qi Wang, Ian Barr, Feng Guo, Christopher Lee

Journal article  |  2008  |  RNA

RNA secondary structures play several important roles in the human immunodeficiency virus (HIV) life cycle. To assess whether RNA ..

Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries

IG Barr, YM Deng, P Iannello, AC Hurt, N Komadina

Journal article  |  2008  |  Antiviral Research

A commercial ELISA detects high levels of human H5 antibody but cross-reacts with influenza A antibodies.

Sacha Stelzer-Braid, Bruce Wong, Peter Robertson, Garry W Lynch, Karen Laurie, Robert Shaw, Ian Barr, Paul W Selleck, Cristina Baleriola, Ros Escott, Gregory Katsoulotos, William D Rawlinson

Journal article  |  2008  |  Journal of Clinical Virology

BACKGROUND AND OBJECTIVES: Commercial serological assays to determine influenza A H5N1 infection are available, although the accur..

Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses

Colin A Russell, Terry C Jones, Ian G Barr, Nancy J Cox, Rebecca J Garten, Vicky Gregory, Ian D Gust, Alan W Hampson, Alan J Hay, Aeron C Hurt, Jan C de Jong, Anne Kelso, Alexander I Klimov, Tsutomu Kageyama, Naomi Komadina, Alan S Lapedes, Yi P Lin, Ana Mosterin, Masatsugu Obuchi, Takato Odagiri, et al.

Journal article  |  2008  |  Vaccine

MDCK-SIAT1 cells show improved isolation rates for recent human influenza viruses compared to conventional MDCK cells.

Ding Yuan Oh, Ian G Barr, Jenny A Mosse, Karen L Laurie

Journal article  |  2008  |  Journal of Clinical Microbiology

The ability to isolate and propagate influenza virus is an essential tool for the yearly surveillance of circulating virus strains..

Heterosubtypic T-cell responses against avian influenza H5 haemagglutinin are frequently detected in individuals vaccinated against or previously infected with human subtypes of influenza.

Kylie Goy, Sally Von Bibra, Jenny Lewis, Karen Laurie, Ian Barr, David Anderson, Margaret Hellard, Rosemary Ffrench

Journal article  |  2008  |  Influenza and Other Respiratory Viruses

BACKGROUND: Cellula r immune responses play a critical role in providing help for the production of neutralizing antibodies to inf..

Annual report of the National Influenza Surveillance Scheme, 2007.

Rhonda Owen, Ian G Barr, Andrew Pengilley, Conan Liu, Bev Paterson, Marlena Kaczmarek, undefined National Influenza Surveillance Scheme

Journal article  |  2008  |  Communicable diseases intelligence

The year 2007 saw the most severe influenza season since national reporting of influenza began in 2001. Early in the season the Na..

Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1)

Nadezhda E Yun, Nathaniel S Linde, Michele A Zacks, Ian G Barr, Aeron C Hurt, Jeanon N Smith, Natallia Dziuba, Michael R Holbrook, Lifang Zhang, John M Kilpatrick, C Shane Arnold, Slobodan Paessler

Journal article  |  2008  |  Virology

The global circulation of seasonal influenza A (H3N2) viruses

Colin A Russell, Terry C Jones, Ian G Barr, Nancy J Cox, Rebecca J Garten, Vicky Gregory, Ian D Gust, Alan W Hampson, Alan J Hay, Aeron C Hurt, Jan C de Jong, Anne Kelso, Alexander I Klimov, Tsutomu Kageyama, Naomi Komadina, Alan S Lapedes, Yi P Lin, Ana Mosterin, Masatsugu Obuchi, Takato Odagiri, et al.

Journal article  |  2008  |  Science

Higher than expected seasonal influenza activity in Victoria, 2007.

Emma R Miller, James E Fielding, Kristina A Grant, Ian G Barr, Georgina Papadakis, Heath A Kelly

Journal article  |  2008  |  Communicable diseases intelligence

In 2007, the Victorian influenza season exceeded normal seasonal activity thresholds. The average rate of influenza-like illness (..

Influenza viruses with reduced sensitivity to the neuraminidase inhibitor drugs in untreated young children.

Aeron C Hurt, Ian G Barr

Journal article  |  2008  |  Communicable diseases intelligence

The neuraminidase inhibitors are a class of antiviral drugs used for both the prophylaxis and treatment of influenza infections. C..

Neuraminidase inhibitor drug susceptibility differs between influenza N1 and N2 neuraminidase following mutagenesis of two conserved residues

Hui-Ting Ho, Aeron C Hurt, Jenny Mosse, Ian Barr

Journal article  |  2007  |  Antiviral Research

Genetic analysis of two influenza A (H1) swine viruses isolated from humans in Thailand and the Philippines

N Komadina, V Roque, P Thawatsupha, J Rimando-Magalong, S Waicharoen, E Bomasang, P Sawanpanyalert, M Rivera, P Iannello, AC Hurt, IG Barr

Journal article  |  2007  |  Virus Genes

The emergence of adamantane resistance in influenza A(H1) viruses in Australia and regionally in 2006

IG Barr, AC Hurt, N Deed, P Iannello, C Tomasov, N Komadina

Journal article  |  2007  |  Antiviral Research

Annual report of the National Influenza Surveillance Scheme, 2006.

Kathleen O'Brien, Ian G Barr

Journal article  |  2007  |  Communicable diseases intelligence

Influenza surveillance in Australia is based on laboratory isolation of influenza viruses, sentinel general practitioner reports o..

Performance of six influenza rapid tests in detecting human influenza in clinical specimens

Aeron C Hurt, Robert Alexander, Jan Hibbert, Nicola Deed, Ian G Barr

Journal article  |  2007  |  Journal of Clinical Virology

Loop-mediated isothermal amplification for influenza A (H5N1) virus.

Shanthi Jayawardena, Chung Y Cheung, Ian Barr, Kwok H Chan, Honglin Chen, Yi Guan, JS Malik Peiris, Leo LM Poon

Journal article  |  2007  |  Emerging Infectious Diseases

We describe a 1-step reverse-transcription loop-mediated isothermal amplification assay for detection of highly pathogenic avian i..

Reliable universal RT-PCR assays for studying influenza polymerase subunit gene sequences from all 16 haemagglutinin subtypes.

Olive TW Li, Ian Barr, Connie YH Leung, Honglin Chen, Yi Guan, JS Malik Peiris, Leo LM Poon

Journal article  |  2007  |  Journal of Virological Methods

Realizable one-step RT-PCR assays specific for influenza PB2, PB1 and PA segments are described in this report. The designs of the..

Susceptibility of highly pathogenic A(H5N1) avian influenza viruses to the neuraminidase inhibitors and adamantanes

AC Hurt, P Selleck, N Komadina, R Shaw, L Brown, IG Barr

Journal article  |  2007  |  Antiviral Research

Increased adamantane resistance in influenza A(H3) viruses in Australia and neighbouring countries in 2005

IG Barr, AC Hurt, P Iannello, C Tomasov, N Deed, N Komadina

Journal article  |  2007  |  Antiviral Research

Laboratory diagnosis of human seasonal and pandemic influenza virus infection.

Dominic E Dwyer, David W Smith, Michael G Catton, Ian G Barr

Journal article  |  2006  |  Medical Journal of Australia

Laboratory diagnosis is important to distinguish influenza from other respiratory virus infections. It will be especially importan..

Identification of genetic diversity by cultivating influenza A(H3N2) virus in vitro in the presence of post-infection sera from small children.

LR Haaheim, CC Tomasov, IG Barr, AW Hampson, N Komadina

Journal article  |  2006  |  Vaccine

Antigenic variants probably arise in the field by escaping herd immunity. We have earlier found that sera from small children are ..

The rapid identification of human influenza neuraminidase N1 and N2 subtypes by ELISA.

IG Barr, M McCaig, C Durrant, R Shaw

Journal article  |  2006  |  Vaccine

An ELISA assay was developed to allow the rapid and accurate identification of human influenza A N1 and N2 neuraminidases. Initial..

Isolation of avian influenza viruses from two different transhemispheric migratory shorebird species in Australia

AC Hurt, PM Hansbro, P Selleck, B Olsen, C Minton, AW Hampson, IG Barr

Journal article  |  2006  |  Archives of Virology

Vaccination with recombinant adhesins from the RgpA-Kgp proteinase-adhesin complex protects against Porphyromonas gingivalis infection

Leanne T Frazer, Neil M O'Brien-Simpson, Nada Slakeski, Katrina A Walsh, Paul D Veith, Chao Guang Chen, Ian G Barr, Eric C Reynolds

Journal article  |  2006  |  Vaccine

Resistance to anti-influenza drugs: adamantanes and neuraminidase inhibitors.

Aeron C Hurt, Hui-Ting Ho, Ian Barr

Journal article  |  2006  |  Expert Review of Anti-infective Therapy

Development of effective drugs for the treatment or prevention of epidemic and pandemic influenza is important in order to reduce ..

Outbreak of influenza amongst residential school students in Malaysia.

A Ayob, N Selviendran, AW Hampson, IG Barr, V Kumarasamy, KB Chua

Journal article  |  2006  |  Medical Journal of Malaysia

In the months of July and August 2003, an outbreak of acute respiratory illness caused by influenza A virus occurred among student..

Neuraminidase inhibitor-resistant and -sensitive influenza B viruses isolated from an untreated human patient

AC Hurt, P Iannello, K Jachno, N Komadina, AW Hampson, IG Barr, JL McKimm-Breschkin

Journal article  |  2006  |  Antimicrobial Agents and Chemotherapy

Reactogenicity and immunogenicity of an inactivated influenza vaccine administered by intramuscular or subcutaneous injection in elderly adults.

Ian F Cook, Ian Barr, Gunter Hartel, Dimity Pond, Alan W Hampson

Journal article  |  2006  |  Vaccine

In many countries there is no clear recommendation regarding the preferred route of administration of inactivated influenza vaccin..

Specific detection of H5N1 avian influenza A virus in field specimens by a one-step RT-PCR assay.

Lisa Fp Ng, Ian Barr, Tung Nguyen, Suriani Mohd Noor, Rosemary Sok-Pin Tan, Lora V Agathe, Sanjay Gupta, Hassuzana Khalil, Thanh Long To, Sharifah Syed Hassan, Ee-Chee Ren

Journal article  |  2006  |  BMC Infectious Diseases

BACKGROUND: Continuous outbreaks of the highly pathogenic H5N1 avian influenza A in Asia has resulted in an urgent effort to impro..

Circulation and antigenic drift in human influenza B viruses in SE Asia and Oceania since 2000.

Ian G Barr, Naomi Komadina, Chris Durrant, Helen Sjogren, Aeron C Hurt, Robert P Shaw

Journal article  |  2006  |  Communicable diseases intelligence

During annual influenza epidemics, influenza B viruses frequently co-circulate with influenza A viruses and in some years, such as..

An influenza A(H3) reassortant was epidemic in Australia and New Zealand in 2003

IG Barr, N Komadina, AC Hurt, P Iannello, C Tomasov, R Shaw, C Durrant, H Sjogren, AW Hampson

Journal article  |  2005  |  Journal of Medical Virology

Laboratory-based influenza surveillance in New Caledonia, 1999-2003.

Alain Berlioz-Arthaud, Ian G Barr

Journal article  |  2005  |  Transactions of the Royal Society of Tropical Medicine and Hygiene

We aimed to evaluate the annual incidence of influenza in New Caledonia and to identify the circulating viral types and subtypes i..

A comparison of a rapid test for influenza with laboratory-based diagnosis in a paediatric population.

R Alexander, AC Hurt, D Lamb, FY Wong, AW Hampson, IG Barr

Journal article  |  2005  |  Communicable diseases intelligence

In vitro generation and characterisation of an influenza B variant with reduced sensitivity to neuraminidase inhibitors

AL Cheam, IG Barr, AW Hampson, J Mosse, AC Hurt

Journal article  |  2004  |  Antiviral Research

Identification of a human influenza type B strain with reduced sensitivity to neuraminidase inhibitor drugs

AC Hurt, JL McKimm-Breschkin, M McDonald, IG Barr, N Komadina, AW Hampson

Conference Proceedings  |  2004  |  Virus Research

A novel means of identifying the neuraminidase type of currently circulating human A(H1) influenza viruses

AC Hurt, IG Barr, N Komadina, AW Hampson

Conference Proceedings  |  2004  |  Virus Research

Susceptibility of human influenza viruses from Australasia and South East Asia to the neuraminidase inhibitors zanamivir and oseltamivir

AC Hurt, IG Barr, G Hartel, AW Hampson

Journal article  |  2004  |  Antiviral Research

Characterization of two outer membrane protein antigens of Porphyromonas gingivalis that are protective in a murine lesion model

BC Ross, L Czajkowski, KL Vandenberg, S Camuglia, J Woods, C Agius, R Paolini, E Reynolds, IG Barr

Journal article  |  2004  |  Oral Microbiology and Immunology

Reassortants in recent human influenza A and B isolates from South East Asia and Oceania.

IG Barr, N Komadina, A Hurt, R Shaw, C Durrant, P Iannello, C Tomasov, H Sjogren, AW Hampson

Journal article  |  2003  |  Virus Research

From 2000 to 2002, human influenza A and B viruses that were genetic reassortants of contemporary circulating human strains, were ..

Surveillance for neuraminidase inhibitor resistance in human influenza viruses from Australia.

Aeron C Hurt, Ian G Barr, Christopher J Durrant, Robert P Shaw, Helen M Sjogren, Alan W Hampson

Journal article  |  2003  |  Communicable diseases intelligence

Two hundred and forty-five human influenza A and B viruses isolated in Australia between 1996 and 2003 were tested for their sensi..

Characterization and expression of a novel Porphyromonas gingivalis outer membrane protein, Omp28

N Slakeski, M Margetts, C Moore, L Czajkowski, IG Barr, EC Reynolds

Journal article  |  2002  |  ORAL MICROBIOLOGY AND IMMUNOLOGY

Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis

BC Ross, L Czajkowski, D Hocking, M Margetts, E Webb, L Rothel, M Patterson, C Agius, S Camuglia, E Reynolds, T Littlejohn, B Gaeta, A Ng, ES Kuczek, JS Mattick, D Gearing, IG Barr

Journal article  |  2001  |  Vaccine

Characterization of a novel outer membrane hemin-binding protein of Porphyromonas gingivalis

SG Dashper, A Hendtlass, N Slakeski, C Jackson, KJ Cross, L Brownfield, R Hamilton, I Barr, EC Reynolds

Journal article  |  2000  |  Journal of Bacteriology

Overexpression, purification, and refolding of a Porphyromonas gingivalis cysteine protease from Escherichia coli.

MB Margetts, IG Barr, EA Webb

Journal article  |  2000  |  Protein Expression and Purification

This paper describes the overexpression of the Rgp-1 (arginine) protease domain from Porphyromonas gingivalis. This protease and t..

Strategies for improving responses to DNA vaccines.

JS Boyle, IG Barr, AM Lew

Journal article  |  1999  |  Molecular Medicine

ISCOMs: an adjuvant with multiple functions.

A Sjölander, JC Cox, IG Barr

Journal article  |  1998  |  Journal of Leukocyte Biology

Aluminum salts are currently the only widely used adjuvant for human vaccines. Over the past 10-15 years, a large research effort ..

ISCOMs and other saponin based adjuvants

IG Barr, A Sjölander, JC Cox

Journal article  |  1998  |  Advanced Drug Delivery Reviews

DNA vaccines: Will they deliver?

JS Boyle, CT Agius, AM Lew, IG Barr

Journal article  |  1998  |  Australasian Biotechnology

ISCOMs (immunostimulating complexes): the first decade.

IG Barr, GF Mitchell

Journal article  |  1996  |  Immunology and Cell Biology

A little over a decade ago, novel immunostimulating complexes (ISCOMs) were described. This review examines the position and progr..