Pierre-Antoine Dugue

Does genetic predisposition modify the effect of lifestyle-related factors on DNA methylation?

Chenglong Yu, Allison M Hodge, Ee Ming Wong, Jihoon E Joo, Enes Makalic, Daniel F Schmidt, Daniel D Buchanan, Gianluca Severi, John L Hopper, Dallas R English, Graham G Giles, Roger L Milne, Melissa C Southey, Pierre-Antoine Dugue

Journal article  |  2022  |  EPIGENETICS

Lifestyle-related phenotypes have been shown to be heritable and associated with DNA methylation. We aimed to investigate whether ..

Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking

Dusan Petrovic, Barbara Bodinier, Sonia Dagnino, Matthew Whitaker, Maryam Karimi, Gianluca Campanella, Therese Haugdahl Nost, Silvia Polidoro, Domenico Palli, Vittorio Krogh, Rosario Tumino, Carlotta Sacerdote, Salvatore Panico, Eiliv Lund, Pierre-Antoine Dugue, Graham G Giles, Gianluca Severi, Melissa Southey, Paolo Vineis, Silvia Stringhini, et al.

Journal article  |  2022  |  EUROPEAN JOURNAL OF EPIDEMIOLOGY

Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to sm..

Improving breast cancer risk prediction with epigenetic risk factors

Melissa C Southey, Pierre-Antoine Dugue

Journal article  |  2022  |  NATURE REVIEWS CLINICAL ONCOLOGY

Weight is More Informative than Body Mass Index for Predicting Postmenopausal Breast Cancer Risk: Prospective Family Study Cohort (ProF-SC)

Zhoufeng Ye, Shuai Li, Gillian S Dite, Tuong L Nguyen, Robert J MacInnis, Irene L Andrulis, Saundra S Buys, Mary B Daly, Esther M John, Allison W Kurian, Jeanine M Genkinger, Wendy K Chung, Kelly-Anne Phillips, Heather Thorne, Ingrid M Winship, Roger L Milne, Pierre-Antoine Dugue, Melissa C Southey, Graham G Giles, Mary Beth Terry, et al.

Journal article  |  2022  |  CANCER PREVENTION RESEARCH

UNLABELLED: We considered whether weight is more informative than body mass index (BMI) = weight/height2 when predicting breast ca..

The Role of Epigenetic Clocks in Explaining Educational Inequalities in Mortality: A Multicohort Study and Meta-analysis

Giovanni Fiorito, Sara Pedron, Carolina Ochoa-Rosales, Cathal McCrory, Silvia Polidoro, Yan Zhang, Pierre-Antoine Dugue, Scott Ratliff, Wei N Zhao, Gareth J McKay, Giuseppe Costa, Maria Giuliana Solinas, Kathleen Mullan Harris, Rosario Tumino, Sara Grioni, Fulvio Ricceri, Salvatore Panico, Hermann Brenner, Lars Schwettmann, Melanie Waldenberger, et al.

Journal article  |  2022  |  JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Educational inequalities in all-cause mortality have been observed for decades. However, the underlying biological mechanisms are ..

Association of FOXO3 Blood DNA Methylation with Cancer Risk, Cancer Survival, and Mortality

Chenglong Yu, Allison M Hodge, Ee Ming Wong, Jihoon Eric Joo, Enes Makalic, Daniel Schmidt, Daniel D Buchanan, John L Hopper, Graham G Giles, Melissa C Southey, Pierre-Antoine Dugue

Journal article  |  2021  |  CELLS

Genetic variants in FOXO3 are associated with longevity. Here, we assessed whether blood DNA methylation at FOXO3 was associated w..

Repeatability of methylation measures using a QIAseq targeted methyl panel and comparison with the Illumina HumanMethylation450 assay

Chenglong Yu, Pierre-Antoine Dugue, James G Dowty, Fleur Hammet, JiHoon E Joo, Ee Ming Wong, Mahnaz Hosseinpour, Graham G Giles, John L Hopper, Nguyen-Dumont Tu, Robert J MacInnis, Melissa C Southey

Journal article  |  2021  |  BMC RESEARCH NOTES

OBJECTIVE: In previous studies using Illumina Infinium methylation arrays, we have identified DNA methylation marks associated wit..

Inflammation-Related Marker Profiling of Dietary Patterns and All-cause Mortality in the Melbourne Collaborative Cohort Study

Sherly X Li, Allison M Hodge, Robert J MacInnis, Julie K Bassett, Per M Ueland, Oivind Midttun, Arve Ulvik, Sabina Rinaldi, Klaus Meyer, Anne-Sophie Navionis, Nitin Shivappa, James R Hebert, Leon Flicker, Gianluca Severi, Harindra Jayasekara, Dallas R English, Paolo Vineis, Melissa C Southey, Roger L Milne, Graham G Giles, et al.

Journal article  |  2021  |  JOURNAL OF NUTRITION

BACKGROUND: Nutritional epidemiology research using self-reported dietary intake is prone to measurement error. Objective methods ..

Physical activity and sedentary behaviour over adulthood in relation to all-cause and cause-specific mortality: a systematic review of analytic strategies and study findings

Yi Yang, Suzanne C Dixon-Suen, Pierre-Antoine Dugue, Allison M Hodge, Brigid M Lynch, Dallas R English

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

BACKGROUND: Questions remain about the effect on mortality of physical activity and sedentary behaviour over time. We summarized t..

Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging

Pierre-Antoine Dugue, Allison M Hodge, Arve Ulvik, Per M Ueland, Oivind Midttun, Sabina Rinaldi, Robert J Macinnis, Sherly X Li, Klaus Meyer, Anne-Sophie Navionis, Leon Flicker, Gianluca Severi, Dallas R English, Paolo Vineis, Grethe S Tell, Melissa C Southey, Roger L Milne, Graham G Giles

Journal article  |  2021  |  JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

BACKGROUND: Inflammation is a key feature of aging. We aimed to (i) investigate the association of 34 blood markers potentially in..