Monther Alhamdoosh

Cellular Microenvironment Stiffness Regulates Eicosanoid Production and Signaling Pathways

Asres Berhan, Trudi Harris, Jade Jaffar, Fernando Jativa, Shenna Langenbach, Ingrid Loennstedt, Monther Alhamdoosh, Milica Ng, Peter Lee, Glen Westall, Nick Wilson, Michael Wilson, Alastair G Stewart

Journal article  |  2020  |  AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Pathological changes in the biomechanical environment are implicated in the progression of idiopathic pulmonary fibrosis (IPF). St..

Blockade of the G-CSF Receptor Is Protective in a Mouse Model of Renal Ischemia-Reperfusion Injury

Jennifer L McRae, Ingela B Vikstrom, Anjan K Bongoni, Evelyn J Salvaris, Nella Fisicaro, Milica Ng, Monther Alhamdoosh, Adriana Baz Morelli, Peter J Cowan, Martin J Pearse

Journal article  |  2020  |  JOURNAL OF IMMUNOLOGY

Ischemia-reperfusion injury (IRI) is a complex inflammatory process that detrimentally affects the function of transplanted organs..

A guide to creating design matrices for gene expression experiments.

Charity W Law, Kathleen Zeglinski, Xueyi Dong, Monther Alhamdoosh, Gordon K Smyth, Matthew E Ritchie

Journal article  |  2020  |  F1000Res

Differential expression analysis of genomic data types, such as RNA-sequencing experiments, use linear models to determine the siz..

Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model

Sandra Koernig, Ian K Campbell, Charley Mackenzie-Kludas, Alexander Schaub, Marius Loetscher, Wy Ching Ng, Roland Zehnder, Pawel Pelczar, Ildem Sanli, Monther Alhamdoosh, Milica Ng, Lorena E Brown, Fabian Kasermann, Cedric Vonarburg, Adrian W Zuercher

Journal article  |  2019  |  MUCOSAL IMMUNOLOGY

Recurrent and persistent airway infections remain prevalent in patients with primary immunodeficiency (PID), despite restoration o..

Machine learning applied to whole-blood RNA-sequencing data uncovers distinct subsets of patients with systemic lupus erythematosus

William A Figgett, Katherine Monaghan, Milica Ng, Monther Alhamdoosh, Eugene Maraskovsky, Nicholas J Wilson, Alberta Y Hoi, Eric F Morand, Fabienne Mackay

Journal article  |  2019  |  CLINICAL & TRANSLATIONAL IMMUNOLOGY

Objectives: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that is difficult to treat. There is currentl..