Axel Newton

Postnatal development in a marsupial model, the fat-tailed dunnart (Sminthopsis crassicaudata; Dasyuromorphia: Dasyuridae)

Laura E Cook, Axel H Newton, Christy A Hipsley, Andrew J Pask

Journal article  |  2021  |  COMMUNICATIONS BIOLOGY

Marsupials exhibit unique biological features that provide fascinating insights into many aspects of mammalian development. These ..

Regulation of vertebrate forelimb development and wing reduction in the flightless emu

Axel H Newton, Craig A Smith

Journal article  |  2021  |  DEVELOPMENTAL DYNAMICS

The vertebrate limb is a dynamic structure which has evolved into many diverse forms to facilitate complex behavioral adaptations...

Ontogenetic origins of cranial convergence between the extinct marsupial thylacine and placental gray wolf

Axel H Newton, Vera Weisbecker, Andrew J Pask, Christy A Hipsley

Journal article  |  2021  |  COMMUNICATIONS BIOLOGY

Phenotypic convergence, describing the independent evolution of similar characteristics, offers unique insights into how natural s..

Evolution and expansion of the RUNX2 QA repeat corresponds with the emergence of vertebrate complexity.

Axel H Newton, Andrew J Pask

Journal article  |  2020  |  Communications Biology

Runt-related transcription factor 2 (RUNX2) is critical for the development of the vertebrate bony skeleton. Unlike other RUNX fam..

CHD9 upregulates RUNX2 and has a potential role in skeletal evolution

Axel H Newton, Andrew J Pask

Journal article  |  2020  |  BMC MOLECULAR AND CELL BIOLOGY

BACKGROUND: Changes in gene regulation are widely recognized as an important driver of adaptive phenotypic evolution. However, the..

Widespread cis-regulatory convergence between the extinct Tasmanian tiger and gray wolf

Charles Y Feigin, Axel H Newton, Andrew J Pask

Journal article  |  2019  |  GENOME RESEARCH

The extinct marsupial Tasmanian tiger, or thylacine, and the eutherian gray wolf are among the most widely recognized examples of ..

Letting the 'cat' out of the bag: pouch young development of the extinct Tasmanian tiger revealed by X-ray computed tomography

Axel H Newton, Frantisek Spoutil, Jan Prochazka, Jay R Black, Kathryn Medlock, Robert N Paddle, Marketa Knitlova, Christy A Hipsley, Andrew J Pask

Journal article  |  2018  |  ROYAL SOCIETY OPEN SCIENCE

The Tasmanian tiger or thylacine (Thylacinus cynocephalus) was an iconic Australian marsupial predator that was hunted to extincti..

Investigating the loci that contribute to convergent craniofacial evolution between the thylacine and canids

Axel Newton

Thesis / Dissertation  |  2018

One of the most fundamental questions in evolutionary developmental biology is how phenotypic adaptations are controlled at the mo..

Genome of the Tasmanian tiger provides insights into the evolution and demography of an extinct marsupial carnivore

Charles Y Feigin, Axel H Newton, Liliya Doronina, Juergen Schmitz, Christy A Hipsley, Kieren J Mitchell, Graham Gower, Bastien Llamas, Julien Soubrier, Thomas N Heider, Brandon R Menzies, Alan Cooper, Rachel J O'Neill, Andrew J Pask

Journal article  |  2018  |  NATURE ECOLOGY & EVOLUTION

The Tasmanian tiger or thylacine (Thylacinus cynocephalus) was the largest carnivorous Australian marsupial to survive into the mo..

RUNX2 repeat variation does not drive craniofacial diversity in marsupials

Axel H Newton, Charles Y Feigin, Andrew J Pask

Journal article  |  2017  |  BMC EVOLUTIONARY BIOLOGY

BACKGROUND: Runt-related transcription factor 2 (RUNX2) is a transcription factor essential for skeletal development. Variation wi..