Abdou Hachani

EirA Is a Novel Protein Essential for Intracellular Replication of Coxiella burnetii

Miku Kuba, Nitika Neha, Patrice Newton, Yi Wei Lee, Vicki Bennett-Wood, Abderrahman Hachani, David P De Souza, Brunda Nijagal, Saravanan Dayalan, Dedreia Tull, Malcolm J McConville, Fiona M Sansom, Hayley J Newton

Journal article  |  2020  |  Infection and Immunity

The zoonotic bacterial pathogen Coxiella burnetii is the causative agent of Q fever, a febrile illness which can cause a serious c..

Biogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3

Bhavna Padmanabhan, Laura F Fielden, Abderrahman Hachani, Patrice Newton, David R Thomas, Hyun-Jung Cho, Chen Ai Khoo, Diana Stojanovski, Craig R Roy, Nichollas E Scott, Hayley J Newton

Journal article  |  2020  |  Infection and Immunity

Coxiella burnetii is an obligate intracellular bacterial pathogen that replicates inside the lysosome-derived Coxiella-containing ..

The Campylobacter jejuni Type VI Secretion System Enhances the Oxidative Stress Response and Host Colonization

Janie Liaw, Geunhye Hong, Cadi Davies, Abdi Elmi, Filip Sima, Alexandros Stratakos, Lavinia Stef, Ioan Pet, Abderrahman Hachani, Nicolae Corcionivoschi, Brendan W Wren, Ozan Gundogdu, Nick Dorrell

Journal article  |  2019  |  Frontiers in Microbiology

The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology

Thomas E Wood, Sophie A Howard, Andreas Forster, Laura M Nolan, Eleni Manoli, Nathan P Bullen, Hamish CL Yau, Abderrahman Hachani, Richard D Hayward, John C Whitney, Waldemar Vollmer, Paul S Freemont, Alain Filloux

Journal article  |  2019  |  Cell Reports

Unstable chromosome rearrangements in Staphylococcus aureus cause phenotype switching associated with persistent infections

Romain Guerillot, Xenia Kostoulias, Liam Donovan, Lucy Li, Glen P Carter, Abderrahman Hachani, Koen Vandelannoote, Stefano Giulieri, Ian R Monk, Mayu Kunimoto, Lora Starrs, Gaetan Burgio, Torsten Seemann, Anton Y Peleg, Timothy P Stinear, Benjamin P Howden

Journal article  |  2019  |  Proceedings of the National Academy of Sciences

Type VI secretion and anti-host effectors

Abderrahman Hachani, Thomas E Wood, Alain Filloux

Journal article  |  2016  |  Current Opinion in Microbiology

Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network

Thibault G Sana, Christoph Baumann, Andreas Merdes, Chantal Soscia, Thomas Rattei, Abderrahman Hachani, Cerith Jones, Keiryn L Bennett, Alain Filloux, Giulio Superti-Furga, Rome Voulhoux, Sophie Bleves

Journal article  |  2015  |  mBio

Agrobacterium tumefaciens Deploys a Superfamily of Type VI Secretion DNase Effectors as Weapons for Interbacterial Competition In Planta

Lay-Sun Ma, Abderrahman Hachani, Jer-Sheng Lin, Alain Filloux, Erh-Min Lai

Journal article  |  2014  |  Cell Host & Microbe

The VgrG Proteins Are "a la Carte" Delivery Systems for Bacterial Type VI Effectors

Abderrahman Hachani, Luke P Allsopp, Yewande Oduko, Alain Filloux

Journal article  |  2014  |  Journal of Biological Chemistry

An rhs Gene Linked to the Second Type VI Secretion Cluster Is a Feature of the Pseudomonas aeruginosa Strain PA14

Cerith Jones, Abderrahman Hachani, Eleni Manoli, Alain Filloux

Journal article  |  2014  |  Journal of Bacteriology

Spa13 of Shigella flexneri has a dual role: chaperone escort and export gate-activator switch of the type III secretion system

Youness Cherradi, Abderrahman Hachani, Abdelmounaaim Allaoui

Journal article  |  2014  |  Microbiology

Erratum: The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock (Nature Immunology (2012) 13 (1045-1054))

E Aksoy, S Taboubi, D Torres, S Delbauve, A Hachani, MA Whitehead, WP Pearce, I Berenjeno-Martin, G Nock, A Filloux, R Beyaert, V Flamand, B Vanhaesebroeck

Journal article  |  2013  |  Nature Immunology

A Visual Assay to Monitor T6SS-mediated Bacterial Competition

Abderrahman Hachani, Nadine S Lossi, Alain Filloux

Journal article  |  2013  |  Journal of Visualized Experiments

The p110 delta isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock

Ezra Aksoy, Salma Taboubi, David Torres, Sandrine Delbauve, Abderrahman Hachani, Maria A Whitehead, Wayne P Pearce, Inma Berenjeno-Martin, Gemma Nock, Alain Filloux, Rudi Beyaert, Veronique Flamand, Bart Vanhaesebroeck

Journal article  |  2012  |  Nature Immunology

The Second Type VI Secretion System of Pseudomonas aeruginosa Strain PAO1 Is Regulated by Quorum Sensing and Fur and Modulates Internalization in Epithelial Cells

Thibault G Sana, Abderrahman Hachani, Iwona Bucior, Chantal Soscia, Steve Garvis, Elise Termine, Joanne Engel, Alain Filloux, Sophie Bleves

Journal article  |  2012  |  Journal of Biological Chemistry

Type VI Secretion System in Pseudomonas aeruginosa SECRETION AND MULTIMERIZATION OF VgrG PROTEINS

Abderrahman Hachani, Nadine S Lossi, Alexander Hamilton, Cerith Jones, Sophie Bleves, David Albesa-Jove, Alain Filloux

Journal article  |  2011  |  Journal of Biological Chemistry

High-level antibiotic resistance in Pseudomonas aeruginosa biofilm: the ndvB gene is involved in the production of highly glycerol-phosphorylated beta-(1 -> 3)-glucans, which bind aminoglycosides

Irina Sadovskaya, Evgeny Vinogradov, Jianjun Li, Abderrahman Hachani, Karolina Kowalska, Alain Filloux

Journal article  |  2010  |  Glycobiology

Regulatory RNAs and the HptB/RetS signalling pathways fine-tune Pseudomonas aeruginosa pathogenesis

Christophe Bordi, Marie-Cecile Lamy, Isabelle Ventre, Elise Termine, Abderrahman Hachani, Sandy Fillet, Beatrice Roche, Sophie Bleves, Vincent Mejean, Andree Lazdunski, Alain Filloux

Journal article  |  2010  |  Molecular Microbiology

Characterization of a new periplasmic single-domain rhodanese encoded by a sulfur-regulated gene in a hyperthermophilic bacterium Aquifex aeolicus

Marie-Cecile Giuliani, Cecile Jourlin-Castelli, Gisele Leroy, Aderrahman Hachani, Marie Therese Giudici-Orticoni

Journal article  |  2010  |  Biochimie

The bacterial type VI secretion machine: yet another player for protein transport across membranes

Alain Filloux, Abderrahman Hachani, Sophie Bleves

Journal article  |  2008  |  Microbiology

IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri

Abderrahman Hachani, Latefa Biskri, Giacomo Rossi, Allison Marty, Robert Menard, Philippe Sansonetti, Claude Parsot, Guy Tran Van Nhieu, Maria Lina Bernardini, Abdelmounaaim Allaoui

Journal article  |  2008  |  Microbes and Infection

Cross talk between type III secretion and flagellar assembly systems in Pseudomonas aeruginosa

Chantal Soscia, Abderrahman Hachani, Alain Bernadac, Alain Filloux, Sophie Bleves

Journal article  |  2007  |  Journal of Bacteriology

Transcriptional slippage controls production of type III secretion apparatus components in Shigella flexneri

Christophe Penno, Abderrahman Hachani, Latefa Biskri, Philippe Sansonetti, Abdelmounaim Allaoui, Claude Parsot

Journal article  |  2006  |  Molecular Microbiology

Spa32 regulates a switch in substrate specificity of the type III secreton of Shigella flexneri from needle components to Ipa proteins

J Magdalena, A Hachani, M Chamekh, N Jouihri, P Gounon, A Blocker, A Allaoui

Journal article  |  2002  |  Journal of Bacteriology