Jon Cleary

Substantially thinner internal granular layer and reduced molecular layer surface in the cerebellar cortex of the Tc1 mouse model of down syndrome - a comprehensive morphometric analysis with active staining contrast-enhanced MRI

Da Ma, Manuel J Cardoso, Maria A Zuluaga, Marc Modat, Nick M Powell, Frances K Wiseman, Jon O Cleary, Benjamin Sinclair, Ian F Harrison, Bernard Siow, Karteek Popuri, Sieun Lee, Joanne A Matsubara, Marinko Sarunic, Mirza Faisal Beg, Victor LJ Tybulewicz, Elizabeth MC Fisher, Mark F Lythgoe, Sebastien Ourselin

Journal article  |  2020  |  NEUROIMAGE

Down Syndrome is a chromosomal disorder that affects the development of cerebellar cortical lobules. Impaired neurogenesis in the ..

Ultra-high-field MRI using composite RF (STEP) pulses

Roger Ordidge, Jon Cleary, Rebecca Glarin, Yasmin Blunck, Shawna Farquharson, Brad Moffat

Journal article  |  2020  |  NMR IN BIOMEDICINE

Ultra-high field MRI offers many opportunities to expand the applications of MRI. In order for this to be realized, the technical ..

An Experimental Investigation of White Matter Venous Hemodynamics: Basic Physiology and Disruption in Neuroinflammatory Disease

Scott C Kolbe, Sanuji I Gajamange, Jon O Cleary, Trevor J Kilpatrick

Journal article  |  2020  |  FRONTIERS IN NEUROLOGY

The white matter is highly vascularised by the cerebral venous system. In this paper, we describe a unique blood oxygen-level depe..

Microstructural correlates of 23Na relaxation in human brain at 7 Tesla.

Scott C Kolbe, Warda Syeda, Yasmin Blunck, Rebecca Glarin, Meng Law, Leigh A Johnston, Jon O Cleary

Journal article  |  2020  |  Neuroimage

23Na provides the second strongest MR-observable signal in biological tissue and exhibits bi-exponential T2∗ relaxation in micro-e..

Compressed sensing effects on quantitative analysis of undersampled human brain sodium MRI

Yasmin Blunck, Scott C Kolbe, Bradford A Moffat, Roger J Ordidge, Jon O Cleary, Leigh A Johnston

Journal article  |  2020  |  Magnetic Resonance in Medicine

Purpose The clinical application of sodium MRI is hampered due to relatively low image quality and associated long acquisition tim..

A continuum of T-2(*) components: Flexible fast fraction mapping in sodium MRI

Warda Syeda, Yasmin Blunck, Scott Kolbe, Jon O Cleary, Leigh A Johnston

Journal article  |  2019  |  MAGNETIC RESONANCE IN MEDICINE

PURPOSE: Parameter mapping in sodium MRI data is challenging due to inherently low SNR and spatial resolution, prompting the need ..

Zero-gradient-excitation ramped hybrid encoding (zG(RF)-RHE) sodium MRI

Yasmin Blunck, Bradford A Moffat, Scott C Kolbe, Roger J Ordidge, Jon O Cleary, Leigh A Johnston

Journal article  |  2019  |  MAGNETIC RESONANCE IN MEDICINE

PURPOSE: Fast bi-exponential transverse signal decay compounds sodium image quality. This work aims at enhancing image characteris..

Optimized partial-coverage functional analysis pipeline (OPFAP): a semi-automated pipeline for skull stripping and co-registration of partial-coverage, ultra-high-field functional images

Peter E Yoo, Jon O Cleary, Scott C Kolbe, Roger J Ordidge, Terence J O'Brien, Nicholas L Opie, Sam E John, Thomas J Oxley, Bradford A Moffat

Journal article  |  2018  |  MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE

OBJECTIVE: Ultra-high-field functional MRI (UHF-fMRI) allows for higher spatiotemporal resolution imaging. However, higher-resolut..

3D-multi-echo radial imaging of Na-23 (3D-MERINA) for time-efficient multi-parameter tissue compartment mapping

Yasmin Blunck, Sonal Josan, Syeda Warda Taqdees, Bradford A Moffat, Roger J Ordidge, Jon O Cleary, Leigh A Johnston

Journal article  |  2018  |  MAGNETIC RESONANCE IN MEDICINE

PURPOSE: This work demonstrates a 3D radial multi-echo acquisition scheme for time-efficient sodium (23 Na) MR-signal acquisition ..

7T-fMRI: Faster temporal resolution yields optimal BOLD sensitivity for functional network imaging specifically at high spatial resolution

Peter E Yoo, Sam E John, Shawna Farquharson, Jon O Cleary, Yan T Wong, Amanda Ng, Claire B Mulcahy, David B Grayden, Roger J Ordidge, Nicholas L Opie, Terence J O'Brien, Thomas J Oxley, Bradford A Moffat

Journal article  |  2018  |  NEUROIMAGE

Recent developments in accelerated imaging methods allow faster acquisition of high spatial resolution images. This could improve ..